• Applied Microscopy
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• v.34 no.1
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• pp.1-11
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• 2004

The wound healing is very complex biological processing including inflammatory, reepithelialization and matrix construction. According to the biological systematic category, the ability of the healing is very different. Generally healing ability of the lower animal group has been known more excellent compared to its higher group. Therefore, lower animals have been used as the experimental model to explore the mechanism of the wound healing or repair. To verify histochemical characteristics of the wound healing, we have used skin of the frog (Bombina orientalis) as known common amphibian. At day 1, 10, and 16, the mucous substance was very actively synthesized and strong positive by PAS and Alcian blue (pH 2.5). Day 10 after wounding, margin of the wound was gradually strong positive by PTAH staining for detection of collagen synthesis. At 3 to 6 hour and day 23 to 27, we have found the cell division was active through the MG-P staining, in which the concentration and division of DNA in nucleus was green to deep blue color.

• Korean Journal of Agricultural Science
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• v.4 no.1
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• pp.26-33
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• 1977

We have studied the responce of nitrogen on the newly bred varieties, Yusin and Milyang #23, and the effects of defoliation at maturing stage on the rate of ripened grains under different nitrogen levels. The results obtained are summarized as follows : 1. Milyang #23 as well as Tongil was found to be highly nitrogen responsive variety and showed good grain maturing percentage. The number of grain per unit area affected the total yield under the high levels of nitrogen application. The variety, Yusin, was less responsive to nitrogen and had also less leaf area than other varieties under the high level of nitrogen application. Yusin also seemed to have low maturing percentage due to unbalanced ratio between photosynthetic area and size of storage. 2. The low internodes and leaf blade of Yusin and Milyang #15 were grown too much under high levels of nitrogen and these caused more lodging and less light penetration in pant canopy. 3. The effects of defoliation at maturing stage on yield was high under the high levels of nitrogen application, especially when defoliation was done early stage of maturing. The effects of defoliation appeared to be greates in Tongil than in Milyang #15.

• Journal of the Korean Geographical Society
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• v.33 no.3
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• pp.395-409
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• 1998

The purpose of this paper is to determine the atmospheric conditions in whih urban areas affect the precipitation processes and to evaluate whether certain weather types show more apparent urban effect on precipitation modification over five cities in the southem United States. Each heavy rainstorm is classified into one of three synoptic weather types (frontal storm, airmass storm or tropical disturbance storm). Heavy rainstorm day is defined as day producing rainfall totals that equal o exceed 2 inches (50.08 mm). Houston, Dallass and San Antonio show possible urban effects on rainfall totals and frequencies of heavy rainstorms by airmass storm type while New Orleans and Memphis do not reveal any distinct precipitation enhancements through the synoptic analysis. The results of TSA (Trend Surface Analysis) show that frontal and tropical disturbance storm types have stronger climatic gradients than airmass types and the patterns of rainfall totals have stronger trends than those of rainfall frequencies for the five cities. The results suggest that airmass type events may well reveal possible precipitation enhancements due to urban effects since they are less influenced by a strong climate gradient and they provide favorable conditions for development of urban heat islands. Residual analysis confirms that rainfall totals and frequencies of heavy rainstorms by airmass storm type have positive residuals over the city or the major effect area.

• Applied Microscopy
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• v.29 no.1
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• pp.57-66
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• 1999

The nervous tissue in the cerebral ganglion of Korean planaria was observed using electron microscope. The obtained results are as follows: A cerebral ganglion is composed of the nerve cells, neurosecretory cells, neuroglial cells and neuropils. The nerve cells are round or ovoidal-shaped cells (diameter, $5{\mu}m$), which has a large ellipsoidal nucleus containing the evenly developed heterochromatin. Their cytoplasms were found to be relatively simple, because of their undeveloped cell organelles. The neurosecretory cells are long and ellipsoid or spindle-shaped cells, where there were found a large ellipsoidal nucleus and cytoplasm filled with secretory granules (diameter, 60 nm). The neuroglial cells were seldom observed. They are spindle-shaped cells (size, $6\times0.8{\mu}m$), which were observed mainly among the nerve fibers. The neuropils are formed by the nerve fibers and nerve endings which are filled with mitochondria, neurotubules and secretory granules of four kinds (high electron dense granules of sizes 75 nm, 50 nm and 37 nm, and electron lucent granule of size 30 nm etc.). These granular vesicles are divided into single vesicle type and compound vesicle type in the nerve terminals, and neuronal synapses were observed to be the axo-dendritic and dendro-dendritic synapse type.

• Journal of the Korean Geotechnical Society
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• v.26 no.12
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• pp.71-79
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• 2010

The reliable evaluation of the coefficient of variation (COV) of soil properties is required for the determination of adequate design values and the application of a probabilistic method for the design of geotechnical structures. In this paper, the applicability of methods for estimating the standard deviation, such as the. Three-Sigma Rule and a statistical method, is evaluated by using site investigation data of the Songdo area. It is found that the Three-Sigma Rule provides similar results to those of a statistical method when using $N_{\sigma}$=6 for the property with small variability and $N_{\sigma}$=4.2~5.3 for the property with large variability. It is also observed that, for the undrained shear strength that has an increasing trend with depth, a $N_{\sigma}$ value of 4 is adequate for the evaluation of the variability by the Three-Sigma Rule. The COVs of soil properties determined in this paper could be used in the estimation of the confidence interval and characteristic values of soil properties.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.2
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• pp.389-396
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• 2002

In the present work, we examined the mechanism of vasorelaxant effect of scopoletin, an active constituent of Artemisia capillaris on rat thoracic descending aortic rings. Scopoletin induced a concentration-dependent relaxation in rat thoracic descending aortic rings pre-contracted with phenylephrine (EC/sub 50/ = 238.94±37.4 μM), while it was less effective in rat thoracic descending aortic rings precontracted with high potassium solution (KCI 30 mM). Vasorelaxation by scopoletin was significantly inhibited after endothelial removal, but recovered at high concentration. Pretreatment of rat thoracic descending aortic rings with N/sup G/-nitro-L-arginine (100 μM), a nitric oxide synthase inhibitor, and atropine (1 μM), a muscarinic receptor antagonist, significantly inhibited scopoletin-induced relaxation of rat thoracic descending aortic rings. Neither indomethacin (3 μM), an inhibitor of cydooxygenase, nor propranolol (1 μM), a β -adrenoceptor antagonist, modified the effect of scopoletin. The combination of N/sup G/ -nitro-L-arginine (100 μ M) and miconazole (10 μ M), an inhibitor of cytochrome P 450, did not modify the effect of scopoletin, when compared with pretreatment with N/sup G/-nitro-L-arginine(100 μM) alone. Vasorelaxant effect of scopoletin was inverted by pretreatment with diltiazem (10 μM), a Ca/sup 2+/-channel blocker, at low concentration, while restored at high concentration. Apamin (K/sub ca/-channel blocker, 1 μM), 4-aminopyridine (4-AP, K/sub v/-channel blocker, 1 mM), and tetrodotoxin (TTX, Na/sup +/-channel blocker 1 μM) potentiated the vasorelaxant effect of scopoledn, but glibendamide (K/sub ATP/-channel blocker, 10 μM), tetraetylammonium(TEA, non-selective K-channel blocker, 10 mM) did not affect the relaxation of scopoletin. Free radical scavengers (TEMPO, catalase, mannitol) did not modify vascular tone. These results suggest that nitric oxide, Ca/sup 2+/ -channels play a role in endothelium-dependent relaxations to scopoletin in rat aortas, that apamin, 4-AP, TTX but not glibenclamide, TEA potentiated relaxation to scopoletin mediated by these channels, and that free radicals do not concern to the vasorelaxant effect of scopoletin.

• Journal of Periodontal and Implant Science
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• v.34 no.4
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• pp.819-836
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• 2004

Nowdays, the awareness of implant treatment has grown rapidly among dentists and patients alike in Korea, as it becomes a widely accepted treatment. The reason is that unlike crown and bridge or denture treatment, implant treatment helps preserve existing bone and improve masticatory functions. So, It is needed understanding about the type, distribution of implant patient. The following results on patient type and implant distribution were compiled from 4433 implant cases of 1596 patients treated at the periodontal dept. of Y University Hospital during 1992 to 2004. 1. There are no dissimilarities between men and women, with patients in their 40, 50s accounting for 52.5% of patients and 57.5% of implant treatments; the largest share of patients and implant treatments. 2. Mn. posterior area accounted for 54.9% of implant treatments followed by Mx. posterior area(27.6%), Mx anterior area(11.9%) and Mn anterior area(5.6%). 3. Partial edentulous patients treated by single crown and bridge-type prosthesis accounted for 97.5% and fully edentulous patient accounted for the remaining 2.5%. 4. The major cause of tooth loss is periodontal disease, followed by dental caries, trauma and congenital missing. Also, older people are more likely to suffer from tooth loss due to periodontal disease rather than dental caries. 5. In the distribution of bone quality for maxillae, type III was most, followed by type II, r type IV and r type I. As for mandible, type II was most, followed by type III, type IV and for type I. 6. In the distribution of bone quantity for maxillae, type C was most, followed by type B, type D, type A, and for type E. As for mandible, type B was 52% most, followed by type C, type D, type A and type E. 7. The majority of implants were those of 1O-14mm in length (85.2%) and regular diameter in width (64%). The results provided us with basic data on patient type, implant distribution, bone condition, etc. We wish that our results coupled with other research data helps assist in the further study for better implant success/survival rates, etc.

• BMB Reports
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• v.45 no.12
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• pp.742-747
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• 2012

Granulocyte colony-stimulating factor (G-CSF) is used for heart failure therapy and promotes myocardial regeneration by inducing mobilization of bone marrow stem cells to the injured heart after myocardial infarction; however, this treatment has one weakness in that its biological effect is transient. In our previous report, we generated 5 mutants harboring N-linked glycosylation to improve its antiapoptotic activities. Among them, one mutant (Phe140Asn) had higher cell viability than wild-type hG-CSF in rat cardiomyocytes, even after treatment with an apoptotic agent ($H_2O_2$). Cells treated with this mutant significantly upregulated the antiapoptotic proteins, and experienced reductions in caspase 3 activity and PARP cleavage. Moreover, the total number of apoptotic cells was dramatically lower in cultures treated with mutant hG-CSF. Taken together, these results suggest that the addition of an N-linked glycosylation was successful in improving the antiapoptotic activity of hG-CSF, and that this mutated product will be a feasible therapy for patients who have experienced heart failure.

• Journal of the Korean Society of Radiology
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• v.11 no.2
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• pp.87-94
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• 2017

Monte Carlo simulations were used to assess dose enhancement effects for 60-, 90-, 120-, and 150-kV X-rays, and for 6- and 15-MV X-rays. The MCNPX code was used for a computer simulation of the ICRU slab phantom, and gold, gadolinium, and iron oxide (Fe2O3) were employed as dose enhancement agents. In consideration of the buildup region of the incident energy, agent concentrations of 5, 10, 15, and 20 mg/g were inserted on the surface of the phantom at a depth of 5 cm. Based on baseline values obtained in the absence of dose enhancement agents, a quantitative analysis was performed by evaluating depth-dependent changes in the absorbed energy and the dose enhancement factor (DEF). A higher concentration of dose enhancement agents led to a greater dose enhancement effect with iron oxide, gadolinium, and gold in descending order. For kilovoltage (kV) X-rays, as the incident energy was decreased and as the energy became closer to the ionization potential of the atoms in the enhancement agent, the dose enhancement effect increased. In the megavoltage (MV) X-ray range, dose enhancement was higher at 6 MV compared with 15 MV. However, the overall dose enhancements were significantly lower compared to the results obtained with kV X-rays.

• Fire Science and Engineering
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• v.24 no.3
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• pp.131-138
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• 2010

Experimental and numerical studies were conducted to investigate the thermal and chemical characteristics of heptane fires in a full-scale ISO 9705 room. Representative fire conditions were considered for over-ventilated fire (OVF) and under-ventilated fire (UVF). Fuel flow rate and doorway width were changed to create OVF and UVF conditions. Detailed comparisons of temperature and species concentrations between experimental and numerical data were presented in order to validate the predictive performance of FDS (Fire Dynamic Simulator). The OVF and UVF were explicitly characterized with distributions of temperature and product formation measured in the upper layer, as well as combustion efficiency and global equivalence ratio. It was shown that the numerical results provided a quantitatively realistic prediction of the experimental results observed in the OVF conditions. For the UVF, the numerically predicted temperature showed reasonable agreement with the measured temperature. The predicted steady-state volume fractions of $O_2$, $CO_2$, CO and THC also agreed quantitatively with the experimental data. Although there were some limitations to predict accurately the transient behavior in terms of CO production/consumption in the UVF condition, it was concluded that the current FDS was very useful tool to predict the fire characteristics inside the compartment for the OVF and UVF.