Mechanism of Relaxation of Rat Aorta by Scopoletin; an Active Constituent of Artemisia Capillaris |
Kwon Eui Kwang
(Professional Graduate School of Oriental Medicine, Wonkwang University)
Jin Sang Sik (Professional Graduate School of Oriental Medicine, Wonkwang University) oChoi Min H (Professional Graduate School of Oriental Medicine, Wonkwang University) Hwang Kyung Taek (Professional Graduate School of Oriental Medicine, Wonkwang University) Shim Jin Chan (Professional Graduate School of Oriental Medicine, Wonkwang University) Hwang Il Taek (Professional Graduate School of Oriental Medicine, Wonkwang University) Han Jong Hyun (Professional Graduate School of Oriental Medicine, Wonkwang University) |
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Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator.
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Ca<TEX>$^{2+}$</TEX>-stimulated mitochondrial reactive oxygen species generation and permeability transition are inhibited by dibucaine or Mg<TEX>$^{2+}$</TEX>.
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A stable nonfluorescent derivative of resorufin for the fluorometric determination of trace hydrogen peroxide: Applications in detecting the activity of phagocyte NADPH oxidase and other oxidases.
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NADPH oxidation catalyzed by the peroxidase/<TEX>$H_{2}O_{2}$</TEX> system: Guaiacol-mediated and scopoletin-mediated oxidation of NADPH to NADP+.
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Primary endothelial dysfunction: Atherosclerosis.
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Calcium-dependent and -independent activation of the endothelial NO synthase.
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NO: the primary EDRF.
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The alternative: EDHF
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Hydroxyl radical - a mediator of acetylcholine- induced vascular relaxtion.
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Time course of changes in endothelium -dependent and -independent relaxation of chronically diabetic aorta: role of reactive oxygen species.
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U. Nitric oxide in the pathogenesis of vascular disease.
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Studies on choleretic constituent in Artemisia capillaris THUNB.
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In eNOS knockout mice skeletal muscle arteriolar dilation to acetylchorine is mediated by EDHF.
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Mechanism of the hypotensive effect of scopoletin isolated from the fruit of Tetrapleura tetraptera.
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Cardiovascular and neuromuscular action of scopoletin from the fruit of Tetrapleura tetraptera.
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Transient and steady-state kinetics of the oxidation of scopoletin by horseradish peroxidase compounds Ⅰ, Ⅱ and Ⅲ in the presence of NADH.
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Components of acetylcholine-induced dilation in isolated rat arterioles.
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Endothelium-derived nitric oxide: action and properties.
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Endothelium -dependent relaxation resistant to NG-nitro-L-arginine in rat aorta.
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A major role for prostacyclin in nitric oxide-induced occular vasorelaxation in the piglet.
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Endothelium-derived hyperpolarizing factor - fact or fiction?
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Scopoletin: an inducible nitric oxide synthesis inhibitory active constituent from Artemisia feddei.
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In vitro inducible nitric oxide synthesis inhibitory active constituents from Fraxinus rhynchophylla.
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Choleretic effect of Artemisia capllaris extract in rats.
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Production of holeretic substances in the capitulum, leaf and stem of Artemisia capillaris during the plant growth cycle.
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Hepatoprotective activity of scopoletin, a constituent of Solarum lyratum.
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Antihepatotoxic principles of Artemisia capillaris buds.
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Agonist -dependent difference in the relationship between cytosolic Ca<TEX>$^{2+}$</TEX> level and release of vascular relaxing factor in the endothelium of rabbit aortic valve.
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Hydrogen peroxide release from human eosinophils on fibronectin: scopoletin enhances eosinophil activation.
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Etomidate and thiopental inhibit the release of endothelium-derived hyperpolarizing factor in the human renal artery.
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Calcium-dependent nitric oxide synthesis in endothelial cytosol is mediated by calmodulin.
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