• Title/Summary/Keyword: $I_2$-convergence

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The Meaning of Study in the Convergence Role of Married Nursing Graduate Students: Focusing on Doctoral Students (기혼 간호대학원생의 융합적 역할 내 학업의 의미 : 박사과정생 중심으로)

  • Lim, Yunmi;Lee, Shinae;Song, Hyeyoung;Park, Hyojung
    • Journal of the Korea Convergence Society
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    • v.9 no.10
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    • pp.507-521
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    • 2018
  • Objectives: The purpose of this study is to explore in depth and deeply the nature and meaning of the academic experience that married nursing graduate students have experienced in their Convergence roles. Methods: Giorgi(2004) method was used the four-step data analysis procedure following the technological phenomena. Participants were four nursing doctoral students who were involved in work, child-care. and education. Data collection was conducted through two in-depth interviews with participants from October to November 2017. Results: Data analysis was structured into 12 concepts and 5 categories, centered on thinking, feelings, and changes in life for study before and after entering graduate school. The five categories are 'I enjoy flying more than anyone', 'I am different from them', 'A solitary journey toward a dream', 'Family is my strength' and 'I have a dream.' Conclusions: In order to help married nurses improve their professionalism, it is necessary to build a support system for the family, improvement of the organizational culture, and a socially practical support system.

Acceleration of Mesenchymal-to-Epithelial Transition (MET) during Direct Reprogramming Using Natural Compounds

  • Seo, Ji-Hye;Jang, Si Won;Jeon, Young-Joo;Eun, So Young;Hong, Yean Ju;Do, Jeong Tae;Chae, Jung-il;Choi, Hyun Woo
    • Journal of Microbiology and Biotechnology
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    • v.32 no.10
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    • pp.1245-1252
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    • 2022
  • Induced pluripotent stem cells (iPSCs) can be generated from somatic cells using Oct4, Sox2, Klf4, and c-Myc (OSKM). Small molecules can enhance reprogramming. Licochalcone D (LCD), a flavonoid compound present mainly in the roots of Glycyrrhiza inflata, acts on known signaling pathways involved in transcriptional activity and signal transduction, including the PGC1-α and MAPK families. In this study, we demonstrated that LCD improved reprogramming efficiency. LCD-treated iPSCs (LCD-iPSCs) expressed pluripotency-related genes Oct4, Sox2, Nanog, and Prdm14. Moreover, LCD-iPSCs differentiated into all three germ layers in vitro and formed chimeras. The mesenchymal-to-epithelial transition (MET) is critical for somatic cell reprogramming. We found that the expression levels of mesenchymal genes (Snail2 and Twist) decreased and those of epithelial genes (DSP, Cldn3, Crb3, and Ocln) dramatically increased in OR-MEF (OG2+/+/ROSA26+/+) cells treated with LCD for 3 days, indicating that MET effectively occurred in LCD-treated OR-MEF cells. Thus, LCD enhanced the generation of iPSCs from somatic cells by promoting MET at the early stages of reprogramming.

Electrical Properties of ZnO-Bi2O3-Co3O4 Varistor (ZnO-Bi2O3-Co3O4 바리스터의 전기적 특성)

  • Hong, Youn-Woo;Shin, Hyo-Soon;Yeo, Dong-Hun;Kim, Jin-Ho
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.24 no.11
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    • pp.882-889
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    • 2011
  • In this study, we have investigated the effects of Co doping on I-V curves, bulk trap levels and grain boundary characteristics of ZnO-$Bi_2O_3$ (ZB) varistor. From I-V characteristics the nonlinear coefficient (a) and the grain boundary resistivity (${\rho}_{gb}$) decreased as 32${\rightarrow}$22 and 18.4${\rightarrow}0.6{\times}10^9{\Omega}cm$ with sintering temperature (900~1,300$^{\circ}C$), respectively. Admittance spectra and dielectric functions show two bulk traps of zinc interstitial, $Zn_i^{{\cdot}{\cdot}}$(0.16~0.18 eV) and oxygen vacancy, $V_o^{{\cdot}}$ (0.28~0.33 eV). The barrier of grain boundaries in ZBCo (ZnO-$Bi_2O_3-Co_3O_4$) could be electrochemically single type. However, its thermal stability was slightly disturbed by ambient oxygen because the apparent activation energy of grain boundaries was changed from 0.93 eV at the 460~580 K to 1.13 eV at the 620~700 K. It is revealed that Co dopant in ZB reduced the heterogeneity of the barrier in grain boundaries and stabilized the barrier against the ambient temperature.

Optical and Electrical Properties of $Ti_xSi_{1-x}O_y$ Films

  • Lim, Jung-Wook;Yun, Sun-Jin;Kim, Je-Ha
    • ETRI Journal
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    • v.31 no.6
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    • pp.675-679
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    • 2009
  • $Ti_xSi_{1-x}O_y$ (TSO) thin films are fabricated using plasma-enhanced atomic layer deposition. The Ti content in the TSO films is controlled by adjusting the sub-cycle ratio of $TiO_2$ and $SiO_2$. The refractive indices of $SiO_2$ and $TiO_2$ are 1.4 and 2.4, respectively. Hence, tailoring of the refractivity indices from 1.4 to 2.4 is feasible. The controllability of the refractive index and film thickness enables application of an antireflection coating layer to TSO films for use as a thin film solar cell. The TSO coating layer on an Si wafer dramatically reduces reflectivity compared to a bare Si wafer. In the measurement of the current-voltage characteristics, a nonlinear coefficient of 13.6 is obtained in the TSO films.

Anti-tumor and Anti-inflammatory Effects of Ecklonia cava in CT26 Tumor-bearing BALB/cKorl Syngeneic Mice (CT26 고형암을 내포하는 BALB/cKorl Syngeneic 마우스에서 Ecklonia cava의 항암효과 및 항염증효과)

  • Yu Jeong Roh;Ji Eun Kim;You Jeong Jin;Ayun Seol;Hee Jin Song;Tae Ryeol Kim;Kyeong Seon Min;Eun Seo Park;Ki Ho Park;Dae Youn Hwang
    • Journal of Life Science
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    • v.33 no.11
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    • pp.887-896
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    • 2023
  • The inflammatory response have been considered as one of important targets for cancer treatment because they play a key role during all steps of tumor development including initiation, promotion, malignant conversion and progression. To investigate the anti-inflammatory response during anti-tumor activity of an aqueous extracts of Ecklonia cava (AEC), alterations on the distribution of mast cells and the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), nuclear factor (NF)-κB, inflammasome compositional protein and inflammatory cytokines were examined in CT26 colon tumor-bearing BALB/cKorl syngeneic mice after administrating AEC for five weeks. After treatment of AEC, total weight of tumor and necrotic region of tumor section were significantly decreased compared to vehicle treated group. The number of infiltered mast cells was higher in AEC treated group than vehicle treated group, while the expression levels of COX-2 and iNOS were decreased in AEC treated group. Also, similar decrease pattern were detected in the expression levels of NF-κB, NLR family pyrin domain containing 3 (NLRP3), apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC) and caspase-1 (Cas-1) after AEC treatment although the decrease rate was varied. Furthermore, the mRNA expressions of three inflammatory cytokines including tumor necrosis factor-α (TNF-α), interleukin-1α (IL-1α) and interleukin-6 (IL-6) were remarkably decreased in AEC treated group compared to vehicle treated group. These results suggest that inhibition of inflammatory response may be tightly associated with anti-tumor activity of AEC in CT26 colon tumor-bearing BALB/cKorl syngeneic mice.

A Study on the Performance of Mobile Communication System using Stratospheric Platform (성층권 비행선을 이용한 이동통신 시스템의 성능에 관한 연구)

  • Ko Bong Jin;Kim Hye Young;Cho Sung Eun
    • Journal of the Institute of Convergence Signal Processing
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    • v.1 no.2
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    • pp.115-121
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    • 2000
  • This paper presents the analytic results of outage probability, considering the effect of Rician fading, interference and interference-reduction techniques, when a mobile communication system was constructed by using Stratospheric platform, one of the next generation wireless communication infrastructure which provides high speed multimedia services. The results show that carrier to interference power ratio C/I and fading depth K have an effect on outage probability. That is, outage probability decreases as K value increases for constant C/I value and C/I value increases for constant K value.

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Convergence Studies of NO Homeostasis in Cellular Signalling (세포의 신호전달 과정에서 NO 항상성에 관한 융복합 연구)

  • Oh, Hee-Kyun;Do, Eun-Young;Park, Hae-Ryoung
    • Journal of Digital Convergence
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    • v.13 no.12
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    • pp.461-467
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    • 2015
  • Saussurea lappa is known for a variety of physiological activities as a component but has not known to show the effect of the cellular signaling pathway. We investigated the anti-inflammatory effects by Saussurea lappa ethanol extract on the LPS(lipopolysaccharide) induced nitric oxide (NO) production by RAW 264.7 cell line. It shows the expressions of iNOS and COX-2 at the transcriptional level (RT-PCR). The Saussurea lappa ethanol extract showed transcriptional expression levels of pro-inflammatory cytokine TNF- and IL-$1{\beta}$ induced by LPS(lipolysaccharide) in RAW264.7 cell line. Saussurea lappa ethanol extract reduced the LPS-induced expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) at the RNA levels in a concentration-dependent manner. The finding that ethanol extract of Saussurea lappa has an influence on NO (nitric oxide) homeostasis in the study of the action mechanism on the macrophage-mediated inflammatory reaction was considered in terms of convergence. And it is to provide an important basis for the prevention and treatment of inflammatory diseases in the future.

Antecedent Factors Influencing the Continued Use of Smart Banking by Different Mobile Platforms: Android OS vs. iOS (모바일 플랫폼에 따른 스마트 뱅킹의 지속사용에 영향을 미치는 선행요인: Android OS vs. iOS)

  • Kim, Do-Hyung;Ha, Sung-Ho;Park, KyungBae
    • The Journal of Information Systems
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    • v.24 no.2
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    • pp.209-240
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    • 2015
  • Purpose This study investigates the relationships between various attributes of smart banking (convenience, security, convergence, and economy), user features (familiarity and innovativeness), perceived usefulness, trust, satisfaction, and continuance intentions and provides a comparison of Google's Android OS and Apple's iOS. Design/methodology/approach We considered a sample of 245 respondents and used structural equation modeling to analyze the data. Findings The results indicate that convergence and familiarity significantly affected perceived usefulness and that security and economy significantly affected perceived trust in smart banking services. The relationships of security, economy, and innovativeness to perceived usefulness and those of convenience and familiarity to perceived trust were stronger for the Android OS than for iOS. The study contributes by proposing an integrated framework and providing a comparison between the Android OS and iOS in the context of smart banking.

Interpretation bias modification for social anxiety disorder: Development of computer based cognitive modification program (사회불안장애의 해석편향 연구: 컴퓨터 기반 해석편향 프로그램 개발 및 효과검증)

  • Yoon, Hyae-Young
    • Journal of the Korea Convergence Society
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    • v.8 no.4
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    • pp.111-122
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    • 2017
  • The purpose of this study was to develop a computer-based cognitive bias modification program (CBM-I) and to test the efficacy of CBM-I for college students with social anxiety. Forty socially anxious individuals were randomly assigned to the CBM-I(n=21) or a waiting list condition(n=19). Both groups were assessed at the beginning and the end of the program with interpretation bias and social anxiety symptoms(e.g. B=FNE=Brief-Fear of Negative Evaluation Scale, LSAS=Liebowitz Social Anxiety Scale). The CBM-I modified interpretation by providing positive feedback when participants made benign interpretations and negative feedback in response to threat interpretations. Participants in CBM-I completed three computer sessions over three weeks. The CBM-I successfully decreased social anxiety symptoms compared to the control condition(t=2.35, p<.05; t=4.70, p<.001). This result suggests that interpretation modification may have clinical utility when applied as a multi-session intervention.

PRECONDITIONED GAUSS-SEIDEL ITERATIVE METHOD FOR Z-MATRICES LINEAR SYSTEMS

  • Shen, Hailong;Shao, Xinhui;Huang, Zhenxing;Li, Chunji
    • Bulletin of the Korean Mathematical Society
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    • v.48 no.2
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    • pp.303-314
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    • 2011
  • For Ax = b, it has recently been reported that the convergence of the preconditioned Gauss-Seidel iterative method which uses a matrix of the type P = I + S (${\alpha}$) to perform certain elementary row operations on is faster than the basic Gauss-Seidel method. In this paper, we discuss the adaptive Gauss-Seidel iterative method which uses P = I + S (${\alpha}$) + $\bar{K}({\beta})$ as a preconditioner. We present some comparison theorems, which show the rate of convergence of the new method is faster than the basic method and the method in [7] theoretically. Numerical examples show the effectiveness of our algorithm.