• Journal of applied mathematics & informatics
• /
• 제12권1_2호
• /
• pp.211-218
• /
• 2003

Let H be a Hilbert space, X be a real Banach space, A : H \longrightarrow X be an operator with D(A) dense in H, G： H \longrightarrow H be positive definite, $\chi$ $\in$ D(A) and b $\in$ H. Consider the quadratic programming problem: QP： Minimize $\frac{1}{2}$〈p, $\chi$〉 + 〈$\chi$, G$\chi$〉 subject to A$\chi$= b In this paper, we obtain an explicit solution to the above problem using generalized inverses.

• Animal cells and systems
• /
• 제3권3호
• /
• pp.295-301
• /
• 1999

The nucleotide sequence of a 447 base pair fragment in the mitochondrial cytochrome b gene and the complete sequence of the mitochondrial 12S ribosomal RNA gene, 938 bp, were analyzed to infer inter- and intraspecific genetic relationships of Hyla japonica and H. suweonensis from Korea and H, japonica from Japan. In the mitochondrial cytochrome b gene, genetic differentiation among H. japonica populations were 9.62% and 15.66% between H. japonica and H. suweonensis. Based on the Tamura-Nei distance, the level of sequence divergence ranged from 0.45% to 2.75% within Korean H. japonica, while 8.31%-8.87% between Korean and Japanese H. japonica and 11.51%-12.46% between H. japonica and H. suweonensis. In the neigh-bor-joining tree, Korean populations of H. japonica were clustered first at 2.22% and followed by Japanese H. japonica and H. suweonensis at 8.51% and 12.29%, respectively. In mitochondrial 12S rRNA gene, genetic differentiation between H. japonica and H. suweonensis nras 7.17% (68 bp) including 7 gaps. Based on Tamura-Nei distance, the level of sequence divergence ranged 3.53% between Korean and Japanese H. japonica and from 4.93% to 5.41% between H. japonica and H. suweonensis. Phenogram pattern of the 12S rRNA gene sequence corresponded with that of the mitochondrial cytochrome b gene.

• Journal of Magnetics
• /
• 제6권2호
• /
• pp.66-69
• /
• 2001

The actual magnetic induction waveform of cores in electrical machines is not sinusoidal i.e. higher harmonics are always included. Thus the core loss in actual electrical machines is different from the core loss which is measured by the standard method, because the waveform of magnetic induction should be sinusoidal in the standard testing method. Core loss analysis under higher harmonic induction is always important in electric machine design. In this works we measured the core loss when a hysteresis loop has only one period of an ac minor loop of higher harmonic frequency, depending on the position of the ac minor loop of relative to the fundamental harmonic frequency. From this experiment, the core loss P(B/sub 0/f/sub 0/, B/sub h/, nf/sub 0/)) under a higher harmonic magnetic induction B/sub h/ could be expressed by the linear combination the core loss at fundamental harmonic frequency P/sub c/(B/sub 0/, f/sub 0/), the core loss of ac minor loop at zero induction region of the major hysteresis loop P/sub cL/ (B/sub h/, nf/sub 0/), and the core loss of an ac minor loop in the high induction region of the major hysteresis loop P/sub cH/ (B/sub h/, nf/sub 0/) i.e., P/sub c/, (B/sub 0/, f/sub 0/, B/sub h/, nf/sub 0/)=P/sub c/ (B/sub 0/, f/sub 0/,)+(n-1)[k₁(B/sub 0/) P/sub cL/ (B/sub h/, nf/sub 0/)+(1-k₁(B/sub 0/)) P/sub cH/ (B/sub h/, nf/sub 0/)]. This will be useful formula for electrical machine designers and one of effective methods to predict core loss including higher harmonic induction.

• 대한추나의학회지
• /
• 제2권1호
• /
• pp.169-175
• /
• 2001

Objects : The purpose of this study is find out significant (clinical) effect of applying acupuncture on $zh{\grave{a}}h{\grave{a}}i$(K6, 照海) of ${\bar{U}m-kyo-maek$(陰?脈) and $sh{\bar{e}}nm{\grave{a}}i$(B62, 申?) of Yang-kyo-maek(陽?脈) to a patient of circadian sleep disorder. Methods : We apply acupuncture on $zh{\grave{a}}h{\grave{a}}i$(K6, 照海) and $sh{\bar{e}}nm{\grave{a}}i$(B62, 申?) to a patient of circadian sleep disorder during 2 weeks. We check sleeping time day and night during 14 days. Acupuncture on $zh{\grave{a}}h{\grave{a}}i$(K6, 照海) and $sh{\bar{e}}nm{\grave{a}}i$(B62, 申?) has significant effect to circadian sleep disorder patient. Results : Acupuncture on $zh{\grave{a}}h{\grave{a}}i$(K6, 照海) and $sh{\bar{e}}nm{\grave{a}}i$(B62, 申?) has significant effect to circadian sleep disorder patient. Conclusions : 1. The physio-pathologic phenomenon of sleeping is relative to ${\bar{U}m-kyo-maek$(陰?脈) and Yang-kyo-maek(陽?脈) 2. Acupuncture therapy on $zh{\grave{a}}h{\grave{a}}i$(K6, 照海) and $sh{\bar{e}}nm{\grave{a}}i$(B62, 申?) has significant effect to circadian sleep disorder.

• 한국초전도학회:학술대회논문집
• /
• 한국초전도학회 2008년도 High Temperature Superconductivity Vol.XVIII
• /
• pp.23-23
• /
• 2008

• Journal of Magnetics
• /
• 제18권2호
• /
• pp.155-158
• /
• 2013

FeCoB films were being prepared on a Ru underlayer by using the oblique incidence of sputtered and back-scattered particles which have a high in-plane magnetic anisotropy field $H_k$ above 400 Oe. It is suitable to attain such deposition condition when facing targets sputtering system. The in-plane X-ray diffraction analysis clarified that there is anisotropic residual stress which is the origin of the high in-plane magnetic anisotropy. The directional crystalline alignment and inclination of crystallite growth were also observed. Such anisotropic crystalline structures may affect the anisotropic residual stress in the films. The B content of 5.6 at.% was appropriate to induce such anisotropic residual stress and $H_k$ of 410 Oe in this experiment. The film with B content of 6 at.% possessed large saturation magnetization of 22 kG and high $H_k$ of 500 Oe. The film exhibited high ferromagnetic resonance frequency of 9.2 GHz.

• Biomolecules & Therapeutics
• /
• 제17권4호
• /
• pp.430-437
• /
• 2009

Metabolites of Soyasaponin I, a major constituent of soybean, by human intestinal microflora were investigated by LC-MS/MS analysis. We found four peaks, one parental constituent and three metabolites: m/z 941 [M-H]$^-$, m/z 795 [M-rha-H]$^-$, m/z 441 [aglycone-$H_2O$+H]$^+$, and m/z 633 [M-rha-gal-H]$^-$, which was an unknown metabolite, soyasapogenol B 3-$\beta$-D-glucuronide. When soyasaponin I was incubated with the human fecal microbial fraction from ten individuals for 48 h, soyasaponin I was metabolized to soyasapogenol B via soyasaponin III and soyasapogenol B 3-$\beta$-D-glucuronide or via soyasaponin III alone. Both soyasaponin I and its metabolite soyasapgenol B exhibited estrogenic activity. Soyasaponin I increased the proliferation, mRNA expression of c-fos and pS2, in MCF7 cells more potently than soyasapogenol B. However, soyasapogenol B showed potent cytotoxicity against A549, MCF7, HeLa and HepG2 cells, while soyasaponin I did not. The cytotoxicity of soyasapogenol B may prevent its estrogenic effect from increasing dose-dependently. These findings suggest that orally administered soyasaponin I may be metabolized to soyasapogenol B by intestinal microflora and that soyasapogenol B may express a cytotoxic effect rather than an estrogenic effect.

• Tuberculosis and Respiratory Diseases
• /
• 제49권3호
• /
• pp.332-342
• /
• 2000

연구배경 : 염증매개 사이토카인은 염증성 폐질환의 중요한 매개물질이다. 폐 상피세포는 염증세포에서 분비되는 사이토카인에 의해 interleukin, chemokines, colony stimulating factors와 growth factor등을 생산 및 분비함으로써 국소 염증 부위에서의 사이토카인 network에 중요한 역할을 한다. 따라서 폐 상피세포에서 염증매개 사이토카인의 발현 기전에 대한 이해는 염증성 폐질환의 기전규명과 이에 기초한 새로운 치료법의 개발에 생각된다. 대부분의 사이토카인은 NF-${\kappa}B$전사인자에 의해 발현되는데 폐 상피세포에서 염증매개 사이토키인의 발현과 NF-${\kappa}B/I{\kappa}B$ 경로와의 관련성에 관한 연구는 부족한 실정이다. 방법 : BEAS-2B, A549, NCI-H157, NCI-H719 세포에서 IL-1$\beta$와 TNF-$\alpha$ 자극에 의한 IL-8과 TNF-$\alpha$ mRNA의 발현 양상을 평가하였고 이들의 발현과 관찰하였고 NF-${\kappa}B/I{\kappa}B$ 경로와의 관련성을 평가하기 위하여 IL-l$\beta$와 TNF-$\alpha$ 자극에 의한 NF-${\kappa}B$의 활성화 및 $I{\kappa}B{\alpha}$와 $I{\kappa}B{\beta}$의 분해 양상을 관찰하였다. 폐 상피세포의 종류에 따른 NF-${\kappa}B/I{\kappa}B$ 경로 조절의 기전을 규명하고자 IL-1$\beta$와 TNF-$\alpha$ 자극에 의한 $I{\kappa}B{\alpha}$의 인산화와 기저상태에서 IKK$\alpha$의 발현을 평가하였다. 결과 : BEAS-2B, A549, NCI-H157 세포에서는 IL-1$\beta$와 TNF-$\alpha$ 자극으로 $I{\kappa}B{\alpha}$와 $I{\kappa}B{\beta}$가 분해되었고 NF-${\kappa}B$의 활성화가 관찰되었으며 IL-8과 TNF-$\alpha$mRNA의 발현이 유도되었다. NCI-H719 세포에서는 IL-1$\beta$와 TNF-$\alpha$ 자극으로 $I{\kappa}B$ 분해에 의한 NF-${\kappa}B$의 활성화 및 염증매개 사이토카인의 발현이 관찰되지 않았다. BEAS-2B, A549, NCI-H157 세포에서는 IL-1$\beta$와 TNF-$\alpha$ 자극으로 ${\kappa}B$의 인산화가 관찰되었지만 NCI-H719 세포에서는 관찰되지 않았다. 기저상태의 IKK$\alpha$ 발현은 세포간에 차이가 관찰되지 않았다. 결론 : 폐 상피세포에서 NF-${\kappa}B/I{\kappa}B$ 경로는 염증매개 사이토카인 발현에 매우 중요한 역할을 하고, 일부 세포에서는 NF-${\kappa}B/I{\kappa}B$ 경로 조절의 차이를 보이는데 이는 IKK보다 상위 단계의 세포내 신호전달체계의 이상에 기인한 것으로 생각된다.

• 자원리싸이클링
• /
• 제27권4호
• /
• pp.23-28
• /
• 2018

보론을 함유한 광석이나 2차자원으로부터 보론을 효과적으로 회수하기 위한 습식공정을 개발하기 위해서는 수용액에서 보론산의 농도분포 자료가 필요하다. 보론산은 pH 6 이하의 용액에서 $B(OH)_3$로, pH 12 이상의 용액에서는 $B(OH)_4{^-}$로 존재한다. 그러나 pH 6에서 11사이의 범위에서는 $B(OH)_3$와 $B(OH)_4{^-}$간의 중합체 형성반응이 일어난다. $B_3O_3(OH)_4{^-}$, $B_4O_5(OH){_4}^{2-}$와 같은 중합체의 몰분율은 보론산의 농도에 비례한다.

• 대한수학회보
• /
• 제26권2호
• /
• pp.151-158
• /
• 1989

Let (H, B, .nu.) be an abstract Wiener space where H is a separable Hilbert space with the inner product <.,.> and the norm vertical bar . vertical bar=.root.<.,.>, which is densely and continuously imbedded into a separable Banach space B with the norm ∥.∥ , and .nu. is a probability measure on the Borel .sigma.-algebra B(B) of B which satisfies (Fig.) where $B^{*}$ is the topological dual of B and (.,.) is the natural dual pairing between B and $B^{*}$. We will regard $B^{*}$.contnd.H.contnd.B in the natural way. Thus we have =(y, x) for all y in $B^{*}$ and x in H. Let $R^{n}$ and C denote the n-dimensional Euclidean space and the complex numbers respectively.ctively.