• Journal of fish pathology
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• v.22 no.2
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• pp.125-135
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• 2009

The pharmacokinetic properties of oxolinic acid (OA) were studied after oral administration, intraperitoneal injection and dipping to cultured olive flounder, Paralichthys olivaceus (average 90 g, $23{\pm}1{^{\circ}C}$). Plasma samples were taken at 3, 5, 10, 15, 24, 30, 48, 96 and 144 h post-dose. In oral dosage at 15, 30 and 60 ㎎/㎏, the peak plasma concentrations of OA, which attained at 10~15 h post-dose, were 1.92, 2.45 and 3.72 $\mu{g}/m\ell$, respectively. In intraperitoneal injection with 10 and 20 ㎎/㎏, the peak plasma concentrations of OA, which attained at 10 h post-dose, were 4.1 and 4.8 $\mu{g}/m\ell$, respectively. In dipping in 30 and 50 ppm for 1 h, peak concentrations were observed at 5 h and 30 h post-dose, were 0.22 and 0.38 $\mu{g}/m\ell$, respectively. The kinetic profile of absorption, distribution and elimination of OA in plasma were analyzed fitting to a one-compartment model by WinNonlin program. Calculated parameters for a single oral dosage of 15, 30 and 60 ㎎/㎏, respectively, were: AUC (the area under the concentration-time curve)=70.93, 120.0 and 141.86 $\mu{g}$ $h/m\ell$ $T_{max}$ (time for maximum concentration)=16.22, 20.39 and 17.33 h; $C_{max}$ (maximum concentration)=���D1.61, 2.40 and 3.01 $\mu{g}/m\ell$. Following intraperitoneal injection of 10 and 20 ㎎/㎏, these parameters were AUC=184.7 and 315.92 $\mu{g}$ $h/m\ell$ $T_{max}$=5.91 and 6.26 h; $C_{max}$=4.19 and 4.45 $\mu{g}/m\ell$. Following dipping at 30 and 50 ppm, these parameters were AUC=17.58 and 21.69 $\mu{g}$ $h/m\ell$ $T_{max}$=19.08 and 31.43 h; $C_{max}$x=0.22 and 0.25 $\mu{g}/m\ell$.

• Journal of the Korean Applied Science and Technology
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• v.34 no.1
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• pp.132-141
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• 2017

The objective of this study was to determine the influence of dietary metabolic energy (ME) on blood parameters in duck under heat stress. A total of 240 meat ducks Cherry valley (Anas platyrhynchos) were assigned into four treatment groups with a randomized block design for 42 days. The four treatments were: ME 2900 kcal/kg, ME 3000 kcal/kg, ME 3100 kcal/kg, and ME 3200 kcal/kg. Blood lipid profiles was higher in ME 2900 but lower in ME 3100 and ME 3200 than that of ME 3000 (p < 0.05). Blood aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels were higher in ME 3100 and ME 3200 compared those in ME 3000 (p < 0.05). The blood red cell and platelet profiles were increased in ME 3100 and ME 3200, but reduced in ME 2900 compared to those in ME 3000 (p < 0.05). Among blood electrolytes, chloride ($Cl^-$) concentration was decreased in ME 2900 compared to that in ME 3000. Blood gas $PCO_2$ was reduced in ME 2900 compared to that in ME 3000 (p < 0.05). Blood immunoglobulin (IgG) level was reduced in ME 2900 compared to that in ME 3000 (p < 0.05). Level of stress hormone, corticosterone was increased in ME 2900, but decreased in ME 3100 and ME 3200 compared to that in ME 3000 (p < 0.05).

• Journal of the Korean Geotechnical Society
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• v.35 no.12
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• pp.69-89
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• 2019

Design chart solution and table solution were proposed by Choi et al. (2019a), which conducted a parametric numerical study for the bored PHC piles socketed into weathered rocks through sandy soil layers. Based on the Choi et al. (2019a), the new prediction formulae for mobilized capacity components such as total capacity, total skin friction and skin friction of sand at the settlement of 5% pile diameter were proposed in this study. The proposed prediction formulae (EQ-G1) considers pile diameter, relative embedment length and ${\bar{N}}$ (i.e, corrected N) value and their verification results are as follows. The SRF calculated from the new proposed design method was 71~94%, which are greatly improved compared with results by the existing design method. The design efficiency of bearing capacity was in the range of reasonable design except 4 cases, and the design efficiency of the PHC pile was evaluated as 85%. Therefore, it is possible that allowable compressive load (P_all) of PHC pile can be utilized in the resonable design by means of the new proposed method using EQ-G1 equations. And the other new proposed equations of EQ-G2-3 can be utilized approximately in calculation of axial compressive bearing capacity components for prebored PHC pile.

• Journal of Wetlands Research
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• v.13 no.3
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• pp.633-641
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• 2011

The Philippines is known for its abundant water resources such as the rainfall, where it has a mean annual rainfall range from 965 to 4,100mm. Due to the rapid urbanization of the country, the population in Metro Manila has been continuously increasing hence, the demand for a potable water supply also increases. To mitigate the scarcity of potable water supply, utilization of the water resources should be practiced. Rainwater harvesting is one way to utilize the rainfall runoff. This study analyzedthe potentiality of the rainwater harvesting on residential areas in Metro Manila. A water balance method based spreadsheet was used with input parameters including daily rainfall, catchment area, runoff coefficient, population and the water demand. The efficiency of the domestic water tank was analyzedusing the three different climatic conditions (i.e., minimum, median andmaximum annual rainfalls) and three different types of toilets (i.e., inefficient, conventional and dual-flush toilets). Furthermore, the overflow volume was used to determine which size of rainwater storage was more appropriate for the study area. The results of the study showed that for the three types of rainfall years, only the conventional and dual-flush toilets were suitable for the utilization of rainwater harvesting. The utilization of the $60m^3$ storage tank was sufficient for supplying the demandsof the 90 houses only for a small period of time, 3 months. Based from this study, to fully sustain the long-term water demand of the houses, the enlargement of the tank size having a capacity of 1,100 to $2,500m^3$ is ideal.

• Korean Journal of Materials Research
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• v.2 no.3
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• pp.180-190
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• 1992

Some solutions to several major problems in ZMR such as agglomeration of polysilicon, slips and local substrate melting are described. Experiments are performed with varying polysilicon thickness and capping oxide thickness. The aggmeration can be eliminated when nitrogen is introduced at the capping oxide layer-to-polysilicon interface and polysilicon-to-buried oxide layer interface by annealing the SOI samples at $1100^{\circ}$ in $NH_3$ ambient for three hours. The slips and local substrate melting are removed when the back surface of silicon substrate is sandblasted to produce the back surface roughness of about $20{\mu}m$. The subboundary spacing increases with increasing polysilicon thickness and the uniformity of recrystallized SOI film thickness improves with increasing capping oxide thickness, improving the quality of recrystallized SOI film. When the polysilicon thickness is about $1.0{\mu}m$ and the capping oxide thickness is $2.5{\mu}m$, the thickness variation of the recrystallized SOI film is about ${\pm}200{\AA}$ and the subboundary spacing is about $70-120{\mu}m$.

• Journal of Korea Water Resources Association
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• v.41 no.9
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• pp.863-872
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• 2008

In this study, a series of deposition tests have been conducted on saltwater condition(salinity 32 %o) using an annular flume, in order to estimate depositional properties of kaolinite sediments and to analyze the effect of the initial concentration on them. Total 37 deposition tests have been carried out in three different initial concentrations (1000, 5000, 15000 ppm) with varying the bed shear stress. From these test results, minimum shear stress (or critical shear stress for deposition; ${\tau}_{bmin}$) and the deposition rate parameters (${\sigma}_1,\;({\tau}^*_b-1)_{50},\;{\sigma}_2,\;t_{50}$) for kaolinite sediments have been quantified, and the effects of the initial concentration and salinity on depositional properties of cohesive sediments have been analyzed qualitatively. As the results, ${\tau}_{bmin},\;{\sigma}_1\;and\;({\tau}^*_b-1)_{50}$ are found to be 0.147, 0.74 and $0.65N/m^2$ respectively. Through comparing with results from previous studies, the performance of this study and tests results are shown to be good enough to verify.

• Journal of Korea Water Resources Association
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• v.33 no.3
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• pp.315-330
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• 2000

The GIUH (Geomorphologic Instantaneous Unit Hydrograph) is to be applied to the ungauged or insufficiently gauged basins. For tIris purpose, an accurate estimation of the charactenstlc velocity is one very important part, but any proper method for this has not been developed yet. In case that we have enough rainfall and runoff clata, the estimation of the characteristic velocity may be an easy job, but it is out of the purpose of the GIUH. Remindmg that the purpose of GIUH the characterisbc veloclty should be estimated based on the geomorpholog1c analysis and also be snnple for easy apphcation. In tIris research analysis cmd application of the GruH was given to several sub-basins in Wi-stream river basin, Gono, Donggok and Hyoryung. After deriving the characteristic velocity througn a optimizatlOn process with real data, it is compared w1th several velOCIties der1ved from geOlnoI1Jhoclimatic instantaneous unit hydrograph theory and several other concentration time formulae. The estimated charactenstic velocities using Kerby, Kim, KInematic Wave, and Brasby- Williams formulae found to g1ve the appropriate results. Hmvever, as the Kerby, and the Kinematic Wave require user's decision of the IvIanning's n value, the K1m and the Braby-Williams seem to be more applicable and recommended as characteristic velocity formula.

• Proceedings of the Korea Water Resources Association Conference
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• 2007.05a
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• pp.1194-1199
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• 2007

본 연구에서는 도시배수관망의 간략화 모의 시 지선을 단순 생략하는 것이 아니라 2차원 관망을 1차원으로 전환시키는 방법인 등가하천 개념을 도입하여 도시유역의 유출량 산정에 있어서 여러 지선들을 개별적으로 모의하지 않으면서도 실제 존재하는 지선들의 효과를 고려할 수 있는 방법을 개발하고자 하였다. 자연하천에 대해 개발된 등가하천 개념은 최근의 수문모형의 경향인 물리적 분포형 모형의 복잡성을 피하면서 전통적인 개념적 집중형 모형이 가지는 간편성을 살리고 그 것이 가지고 있는 선형가정의 한계를 극복하기 위한 방안으로서 제안된 방법이다. 등가하천 개념을 도입하여 개발된 모형은 종국적으로 강우-유출관계에 있어서 강우의 크기, 선형 및 비선형성, 유역면적 등이 미치는 영향을 분석하기위한 도구로 개발되었으며, 본 연구에서는 출구로부터 동일 거리 s에 위치한 지점에서의 배수관망의 공간적인 분포 및 집중패턴을 파악하는 폭함수(width function, n(s))와 면적함수(area function, M(s))를 이용하여 관망을 간략화 하였다. 등가관의 수리기하조건 결정은 유역이 정상상태에 도달했을 경우에 대해서 이루어지게 되며 정상상태 모의를 통해 개별 관망단면들에 대해 얻어진 유량(Q), 면적(A), 수심(y) 자료간의 상관관계를 유추하여 Q(A), A(y) 함수를 유도하게 되면 종국적으로 관로홍수추적에 이용되는 지배방정식의 매개변수인 파속계수(c) 및 확산계수(D)를 계산할 수 있게 된다. 본 연구에서는 대상 유역으로 군자 배수구역을 선정하여 유역의 특성과 관망 자료를 수집하고 간략화 기법을 적용한 결과를 분석 하였다.다. 21세기 문화산업에서 우리가 판단하게 될 디자인의 가치는 계몽의 원리에 대한 '역사성'과 '현재성'의 변증법에 달려있는 것이며, 새로운 철학, 새로운 문명, 새로운 세계를 열어가는 것이다.r$ (地理志)에는 추현리와 이미 외리를 언급하면서 상주의 자기제작의 위상을 짐작하는 기록이 언급되면서 전국의 상품의 절반을 담당하고 있었음을 알 수 있었다. $\ulcorner$경상도지리지$\lrcorner$(慶尙道地理志)에는 상주가 8곳으로 1/3의 자기 생산을 담당하고 있었다. $\ulcorner$경상도지리지$\lrcorner$(慶尙道地理志)에는 $\ulcorner$세종실록$\lrcorner$(世宗實錄) $\ulcorner$지리지$\lrcorner$(地理志)와 동년대에 동일한 목적으로 찬술되었음을 알 수 있다. $\ulcorner$경상도실록지리지$\lrcorner$(慶尙道實錄地理志)에는 $\ulcorner$세종실록$\lrcorner$(世宗實錄) $\ulcorner$지리지$\lrcorner$(地理志)와의 비교를 해보면 상 중 하품의 통합 9개소가 삭제되어 있고, $\ulcorner$동국여지승람$\lrcorner$(東國與地勝覽) 에서는 자기소와 도기소의 위치가 완전히 삭제되어 있다. 이러한 현상은 첫째, 15세기

• Journal of the Korea Concrete Institute
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• v.23 no.1
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• pp.77-86
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• 2011

The concrete creep deformation of a hybrid composite section can cause additional deformation of the composite section and the stress relaxation of pre-compressive stress on the concrete section due to partial restraint of the deformation. In this study, the stress relaxation coefficient method (SRCM) is derived for simple analysis of complicate hybrid or composite sections for engineering purpose. Also, an equation of the stress relaxation coefficient (SRC) required for the SRCM is proposed. The SRCM is derived with the parameters of a creep coefficient, section and loading properties using the same method as the constant-creep step-by-step method (CC-SSM). The errors of the SRCM is improved by using the proposed SRC equation than the average SRC's which were estimated from the CC-SSM. The root mean square error (RMSE) of the SRCM with the proposed SRC equation for concrete with creep coefficient less than 3 was less than 1.2% to the creep deformation at the free condition and was 3.3% for the 99% reliability. The proposed SRC equation reflects the internal restraint of composite sections, and the effective modulus of elasticity computed with the proposed SRC can be used effectively to estimate the rigidity of a composite section in a numerical analysis which can be applied in analysis of the external restrain effect of boundary conditions.

• Journal of Korea Water Resources Association
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• v.41 no.5
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• pp.473-482
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• 2008

The purpose of this study is to quantitatively estimate the erosional properties for cohesive sediment from Saemankeum artificial lake. A series of erosion tests were conducted with Chonbuk annular flume, which is the first one constructed in this country and verified with validities. Each erosion tests were conducted under a uniform bed condition but a different bed density respectively, and its critical shear stress for erosion(${\tau}_{ce}$) as well as the erosion rate coefficient (${\varepsilon}_M$) were determined quantitatively. Since the erosional properties of the cohesive sediments vary largely depending in the physico-chemical properties, such properties of Saemankeum sediments were also estimated and their effects on the erosional properties were analyzed. For Saemankeum sediments, it can be seen that ${\tau}_{ce}$ increases from $0.26N/m^2$ to $0.52N/m^2$ and ${\varepsilon}_M$ decreases exponentially from $14.28mg/cm^2\;hr$ to $6.02mg/cm^2\;hr$, as the bed density varies from $1.17g/cm^3$ to $1.34g/cm^3$. The erosional parameters of Saemankeum sediments are found to be remarkably different in quantity as compared with those for cohesive sediments from other sites. Particularly, ${\tau}_{ce}$ for Saemankeum sediments is known to be larger than that of Kunsan sediments but similar with that of Shihwa sediments, while ${\varepsilon}_M$ for Saemankeum sediments is shown to be smaller than that for Kunsan sediments.