• 제목/요약/키워드: $A_A_L$1

검색결과 42,490건 처리시간 0.067초

Metagonimus yokogawai 세르카리아의 감각유두에 관한 연구 (Study on Sensory Papillae of Metagonimus yokogawai Cercaria)

  • 김재진;민득영소진탁
    • Parasites, Hosts and Diseases
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    • 제22권1호
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    • pp.11-20
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    • 1984
  • A number of studies on the papillae of cercariae of trematodes reported that the papillar patterns (or chaetotaxy) of cercariae might be an excellent method to attain better understanding of the digenetic trematodes (Richard, 1971 ; Short and Cartrett, 1973; Bayssade-Dufour, 1979) . The present study was aimed to determine the number, distribution pattern and structure of the sensory papillae of Metagonimus yokogawai cercariae, and to elucidate the chaetotaxy of this digenetic trematode. M. yokogawai cercariae were pipetted from a vial in which infected snails (Semisulcospira libertina) had been kept for 3 hours. The snails were collected from an endemic area of M. yokogawai, Boseong river in west-southern part of Korea. Observations of papillae were based on light microscopy of those stained with silver nitrate, and on scanning electron microscopy The results are summarized as follows: 1, All papillae observed were uniciliated. 2. Cilia in anterior tip were shorter than the others in other portions. 3. The body papillae were arranged in essentially symmetrical patterns, Total number of the papillae was 126(63 pairs) in average; anterior tip 40(20 pairs), ventral 20(10 pairs), lateral 42(21 pairs), and caudal 8(4 pairs). 4. The chaetotany of M. yokogawai cercaria was: Ci cycle ($3+3C_{I}V,{\;}2+2C_{I}L,{\;}2+3C_{I}D),{\;}C_{II}{\;}cycle(2C_{II}V,{\;}1C_{II}L,{\;}2C_{II}D),{\;}C_{lll}{\;}cycle{\;}(1+lC_{III}V,{\;}1C_{IlI}L),{\;}C_{IV}{\;}cycle{\;}(1C_{IV}V,{\;}IC_{lV}L){\;}in{\;}cephalic{\;}region:{\;}A_I(1A_{IV}V,{\;}1+2A_{I}L,{\;}1A_{I}D),{\;}A_{II}(1A_{II}V,{\;}1+3A_{II}L,{\;}1A_{II}D),{\;}A_{III}(1A_{III}V,{\;}1+1A_{III}L,{\;}1A_{III}D){\;}and{\;}A_{IV}(1A_{IV}V,{\;}2A_{IV}L)$ in antacetabular region: $1M_{I}V{\;}and{\;}2M_{I}L$ in median: $1+1P_{I}L,{\;}1P_{II}L,{\;}1P_{II}D,{\;}1P_{III}L,{\;}1P_{IV}L{\;}and{\;}1P_{IV}D$ in postacetabular region: 2-2-2-2 in caudal region.

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AN ANALOGUE OF THE HILTON-MILNER THEOREM FOR WEAK COMPOSITIONS

  • Ku, Cheng Yeaw;Wong, Kok Bin
    • 대한수학회보
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    • 제52권3호
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    • pp.1007-1025
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    • 2015
  • Let $\mathbb{N}_0$ be the set of non-negative integers, and let P(n, l) denote the set of all weak compositions of n with l parts, i.e., $P(n,l)=\{(x_1,x_2,{\cdots},x_l){\in}\mathbb{N}^l_0\;:\;x_1+x_2+{\cdots}+x_l=n\}$. For any element $u=(u_1,u_2,{\cdots},u_l){\in}P(n,l)$, denote its ith-coordinate by u(i), i.e., $u(i)=u_i$. A family $A{\subseteq}P(n,l)$ is said to be t-intersecting if ${\mid}\{i:u(i)=v(i)\}{\mid}{\geq}t$ for all $u,v{\epsilon}A$. A family $A{\subseteq}P(n,l)$ is said to be trivially t-intersecting if there is a t-set T of $[l]=\{1,2,{\cdots},l\}$ and elements $y_s{\in}\mathbb{N}_0(s{\in}T)$ such that $A=\{u{\in}P(n,l):u(j)=yj\;for\;all\;j{\in}T\}$. We prove that given any positive integers l, t with $l{\geq}2t+3$, there exists a constant $n_0(l,t)$ depending only on l and t, such that for all $n{\geq}n_0(l,t)$, if $A{\subseteq}P(n,l)$ is non-trivially t-intersecting, then $${\mid}A{\mid}{\leq}(^{n+l-t-l}_{l-t-1})-(^{n-1}_{l-t-1})+t$$. Moreover, equality holds if and only if there is a t-set T of [l] such that $$A=\bigcup_{s{\in}[l]{\backslash}T}\;A_s{\cup}\{q_i:i{\in}T\}$$, where $$A_s=\{u{\in}P(n,l):u(j)=0\;for\;all\;j{\in}T\;and\;u(s)=0\}$$ and $$q_i{\in}P(n,l)\;with\;q_i(j)=0\;fo\;all\;j{\in}[l]{\backslash}\{i\}\;and\;q_i(i)=n$$.

The Role of L1 and L2 in an L3-speaking Class

  • Kim, Sun-Young
    • 비교문화연구
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    • 제24권
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    • pp.170-183
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    • 2011
  • This study explored how a Chinese college student who previously had not reached a threshold level of Korean proficiency used L1 (Chinese) and L2 (English) as a tool to socialize into Korean (L3) culture of learning over the course of study. From a perspective of language socialization, this study examined the cross-linguistic influence of L1 and L2 on the L3 acquisition process by tracing an approach to language learning and practices taken by the Chinese student as a case study. Data were collected through three methods; interview protocols, various types of written texts, and observations. The results showed that the student used English as a means to negotiate difficulties and expertise by empowering her L2 exposure during the classroom practices. Her ways of using L2 in oral practices could be characterized as the 'Inverse U-shape' pattern, under which she increased L2 exposure at the early stage of the study and shifted the intermediate language to L3 at the later stage of the study. When it comes to the language use in written practices, the sequence of "L2-L1-L3" use gradually changed to the "L2-L3" sequence over time, signifying the importance of interaction between L2 and L3. However, the use of her native language (L1) in a Korean-speaking classroom was limited to a certain aspect of literacy practices (i.e., vocabulary learning or translation). This study argues for L2 communication channel in cross-cultural classrooms as a key factor to determine sustainable learning growth.

Homology modeling of HSPA1L - METTL21A interaction

  • 이승진
    • EDISON SW 활용 경진대회 논문집
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    • 제5회(2016년)
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    • pp.90-95
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    • 2016
  • Heat Shock 70kDa Protein 1-Like(HSPA1L)는 Heat-shock protein70(HSP70) family에 속하는 chaperone protein으로 polypeptide folding, assembly, protein degradation 등 다양한 biological processes에 관여하고 있다. HSPA1L은 human methyltransferase-like protein 21A(METTL21A)에 의해 lysine residue에 methylation이 일어나게 되는데, 암세포에서 일반적인 HSPA1L은 주로 세포질에서 발견되는 반면 methylated HSPA1L의 경우 주로 핵에서 발견이 됨으로써 HSPA1L methylation이 암 세포 성장에 중요할 역할을 할 것이라 추측되며 anti-cancer drug target으로 주목 받고 있다. 하지만 현재 HSPA1L의 구조가 부분적으로만 밝혀져 있어 HSPA1L와 METTL21A가 어떤 residue들이 interaction 하여 binding을 하는지에 대해서 아직 밝혀 지지 않았다. 이로 인해 anti-cancer drug target으로서의 연구에 제한이 있다. 이번 연구에서는 homology modeling(Galaxy-TBM, Galaxy-refine)을 통해 HSPA1L 전체 구조를 밝혀 낸 후, HSPA1L 와 METTL21A를 protein-protein docking을 통해 binding pose 예측을 하였다. 이러한 binding pose를 protein interaction analysis하여 HSPA1L과 METTL21A binding에 관여하는 중요 residue들을 밝혀 냈다. 이러한 structural information은 methylated HSPA1L와 암 세포 성장간의 연관성, 더 나아가 anti-cancer drug 개발로 까지도 이어 질 수 있을 것이라 생각한다.

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칩의 크기가 제한된 단일칩 프로세서를 위한 레벨 1 캐시구조 (A Level One Cache Organization for Chip-Size Limited Single Processor)

  • 주영관;김석일
    • 정보처리학회논문지A
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    • 제12A권2호
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    • pp.127-136
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    • 2005
  • 이 논문에서는 단일 칩 프로세서에서 제한된 공간의 레벨 1 캐시를 구성하고 있는 선인출 캐시 $L_P$와 요구인출 캐시 $L_1$의 합이 일정한 때, $L_1$$L_P$의 크기의 적정한 비율을 실험을 통하여 분석하였다. 실험 결과, $L_1$$L_P$의 합이 16KB일 경우에는 $L_1$을 12KB, $L_P$를 4KB로 구성하고 $L_P$의 선인출 기법과 캐시교체정책은 각각 OBL과 FEO을 적용시키는 레벨 1 캐시 구조가 가장 성능이 우수함을 보였다. 또한 이 분석은 $L_1$$L_P$의 합이 32KB 이상인 경우에는 $L_P$의 선인출 기법으로는 동적필터 기법을 사용하는 것이 유리함을 보였고 32KB의 공간이 가용한 경우에는 $L_1$을 28KB, $L_P$를 4KB로, 64KB가 가용한 경우에는 $L_1$을 48KB, $L_P$를 16KB로 레벨 1 캐시를 분할하는 것이 가장 좋은 성능을 발휘함을 보였다.

PREORDERINGS ON LOCAL GLOBAL RINGS

  • Shin, Kee-Young
    • 충청수학회지
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    • 제8권1호
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    • pp.105-110
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    • 1995
  • Suppose A is a local global ring (with many units) and $T{\subset}A$ is a preordering. Let $a_i{\in}A^*$, $i=1,2,{\cdots},n$ and $a{\in}({\sum}_{i=1}^{l-1}\;a_iT){\cap}A^*$. Then, for any integer l, 1 < l ${\leq}$ n, there exist $x{\in}({\sum}_{i=1}^{l-1}\;a_iT){\cap}A^*$ and $y{\in}({\sum}_{i=l}^n\;a_iT){\cap}A^*$ such that a=x+y.

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고추의 Tobamovirus 저항성 L 유전자좌와 연관된 대립유전자 특이적인 마커 세트 (A Set of Allele-specific Markers Linked to L Locus Resistant to Tobamovirus in Capsicum spp.)

  • 이준대;한정헌;윤재복
    • 원예과학기술지
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    • 제30권3호
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    • pp.286-293
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    • 2012
  • 고추에 있어서 Tobamovirus 저항성은 고추 염색체 11번 긴 팔 끝부분에 위치한 L 유전자좌의 다섯 개 대립유전자($L^0$, $L^1$, $L^2$, $L^3$, and $L^4$)에 의해 조절된다고 알려져 있다. 표현형 분석 없이 L 대립유전자를 구분할 수 있는 분자표지를 개발하기 위해서 다섯 개의 고추 판별 계통{Capsicum annuum Early California Wonder(ECW, $L^0L^0$), C. annuum Tisana($L^1L^1$), C. annuum Criollo de Morelos 334(CM334,$L^2L^2$), Capsicum chinense PI 159236($L^3L^3$), and Capsicum chacoense PI 260429($L^4L^4$)}을 식물재료로 사용하였다. 대립유전자 특이적 분자표지는 고추 판별 계통에 대해 $L^3$ 연관 분자표지(189D23M, A339, and 253A1R)와 BAC 염기서열(FJ597539 and FJ597541)의 PCR 증폭산물 염기서열을 비교 분석하여 개발되었다. 총 53개의 상용 고추 품종 중 48개에서 분자표지에 의한 추정 유전자형과 Tobamovirus{Tobacco mosaic virus(pathotype 0, $P_0$), Tomato mosaicvirus($P_1$), and Pepper mild mottle virus($P_{1,2}$)} 접종 표현형과 일치했다. 결과적으로 본 연구에서 개발된 분자표지는 고추 육종에 있어서 TMV 저항성 도입에 필요한 선발마커로 충분히 활용될 수 있을 것이다.

Pro-apoptotic Effects of S100A8 and S100A9 on human FIP1L1-PDGFRα+ Eosinophilic Leukemia Cells

  • Lee, Ji-Sook
    • 대한의생명과학회지
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    • 제27권2호
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    • pp.95-98
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    • 2021
  • The S100 family proteins act as inducers of cancer cell apoptosis and inflammatory mediators. This study examined the pro-apoptotic mechanism caused by S100A8 and S100A9 in human FIP1L1-PDGFRα-positive eosinophilic leukemia cells. S100A8 and S100A9 elicited the death of EoL-1 cells in a time and dose-dependent manner. The activation of PDGFRα was suppressed by a decrease in PDGFRα after treatment with S100A8 and S100A9. Cycloheximide, a translation inhibitor, suppressed PDGFRα expression from 1 h to 5 h, and a co-treatment with S100A8 and S100A9 boosted the decrease in expression. The phosphorylation and expression of STAT5 decreased after treatment with S100A8 and S100A9 in EoL-1 and imatinib-resistant (EoL-1-IR) cells. S100A8 and S100A9 induced the chemotaxis of EoL-1 cells but did not affect the chemoattraction of EoL-1-IR. These findings indicate the cell death mechanism due to S100 family proteins and the development of leukemia therapy using S100A8 and S100A9.

고추 자엽에서 식물체 재분화의 품종간 차이 (Varietal Difference in Plant Regeneration from Cotyledon Culture of Capsicum annuum L.)

  • 오명규;이영만;박문수
    • 식물조직배양학회지
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    • 제25권5호
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    • pp.301-304
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    • 1998
  • 자엽으로 부터 신초 유기율은 MS기본배지와 MS기본배지에 IAA 0.25mg/L 또는 0.50mg/L과 zeatin 2.0mg/L 또는 4.0mg/L를 단독 및 조합 처리한 배지중에서 M배지에 IAA 0.25mg/L + zeatin 2.0mg/L 첨가된 배지가 63%로 가장 양호하였다. 신초 유기시기는 품종 및 배지에 따라 치상후 9~25일의 차이가 있었는데 MS배지 + zeatin 2.0mg/L + IAA 0.25 mg/L배지에서 영양재래, 풋고추, 342, Kakovskij-A-35, Gris I-A-1가 빠르게 유기 되었으며, MS배지 + BA 2.0mg/L + IAA 1.0mg/L 배지에서 COO485 Long Hot P5-3, Gris I-A-1에서 유기가 빨았다. 신초 유기율도 품종 및 배지에 따라 달랐는데 MS 배지 + zeatin 2.0mg/L + IAA 0.25mg/L 배지에서는 621, 영양재래, Nikko(일광), 적색물고추, Ch-6Num-216, 풋고추, Kakovskij-A-35가, MS배지 + BA 2.0mg/L + IAA 1.0mg/L 배지에서는 Fresno Chile, PI 169126, 적색물고추, PI 297438가 90%이상으로 높았다.

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Two Dimensional Slow Feature Discriminant Analysis via L2,1 Norm Minimization for Feature Extraction

  • Gu, Xingjian;Shu, Xiangbo;Ren, Shougang;Xu, Huanliang
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제12권7호
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    • pp.3194-3216
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    • 2018
  • Slow Feature Discriminant Analysis (SFDA) is a supervised feature extraction method inspired by biological mechanism. In this paper, a novel method called Two Dimensional Slow Feature Discriminant Analysis via $L_{2,1}$ norm minimization ($2DSFDA-L_{2,1}$) is proposed. $2DSFDA-L_{2,1}$ integrates $L_{2,1}$ norm regularization and 2D statically uncorrelated constraint to extract discriminant feature. First, $L_{2,1}$ norm regularization can promote the projection matrix row-sparsity, which makes the feature selection and subspace learning simultaneously. Second, uncorrelated features of minimum redundancy are effective for classification. We define 2D statistically uncorrelated model that each row (or column) are independent. Third, we provide a feasible solution by transforming the proposed $L_{2,1}$ nonlinear model into a linear regression type. Additionally, $2DSFDA-L_{2,1}$ is extended to a bilateral projection version called $BSFDA-L_{2,1}$. The advantage of $BSFDA-L_{2,1}$ is that an image can be represented with much less coefficients. Experimental results on three face databases demonstrate that the proposed $2DSFDA-L_{2,1}/BSFDA-L_{2,1}$ can obtain competitive performance.