• Interaction and multiscale mechanics
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• 제1권2호
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• pp.191-209
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• 2008

In this paper, we model grain boundary evolution based on a multiple level set method. Grain boundary migration under a curvature-induced driving force is considered and the level set method is employed to deal with the resulting topological changes of grain structures. The complexity of using a level set method for modeling grain structure evolution is due to its N-phase nature and the associated geometry compatibility constraint. We employ a multiple level set method with a predictor-multicorrectors approach to reduce the gaps in the triple junctions down to the grid resolution level. A ghost cell approach for imposing periodic boundary conditions is introduced without solving a constrained problem with a Lagrange multiplier method or a penalty method. Numerical results for both uniform and random grain structures evolution are presented and the results are compared with the solutions based on a front tracking approach (Chen and Kotta et al. 2004b).

• Bulletin of the Korean Chemical Society
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• 제24권2호
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• pp.178-182
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• 2003

The stress and the heat-flux auto-correlation functions in the Green-Kubo formulas for shear viscosity and thermal conductivity have non-decaying long-time tails. This problem can be overcome by improving the statistical accuracy by N (number of particles) times, considering the stress and the heat-flux of the system as properties of each particle. The mean square stress and the heat-flux displacements in the Einstein formulas for shear viscosity and thermal conductivity are non linear functions of time since the quantities in the mean square stress and the heat-flux displacements are not continuous under periodic boundary conditions. An alternative to these quantities is to integrate the stress and the heat-flux with respect to time, but the resulting mean square stress and heat-flux displacements are still not linear versus time. This problem can be also overcome by improving the statistical accuracy. The results for transport coefficients of liquid argon obtained are discussed.

• Progress in Superconductivity
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• 제11권2호
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• pp.158-161
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• 2010

We measured the critical current of a Cooper pair transistor consisting of two Josephson junctions and a gate electrode. The Cooper pair transistors were fabricated by using electron-beam lithography and double-angle evaporation technique. The Gate voltage dependence of critical current was measured by observing voltage jumps at various gate voltages while sweeping bias current. The observed oscillation was 2e-periodic, which shows the Cooper pair transistor had low level of quasiparticle poisoning.

• 대한조선학회논문집
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• 제41권2호
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• pp.90-97
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• 2004

Flow mechanism of contractive and dilative motion is numerically investigated to obtain a propulsive force in highly viscous fluid. An axisymmetric code is developed with unstructured grid system based on cell-centered scheme. It is validated by comparing with the results of Stokes approximation for the problem of uniform flow past a sphere in low Reynolds number(R$_{n}$=1). The validated code is applied to the simulation of contractive and dilative periodic motion of body whose results are quantitatively compared with the two dimensional case. In order to investigate the grid dependency, two different grids are applied to the present computations. The present study provides key information for the development of an axisymmetric Micro-hydro-robot.t.

• 대한기계학회논문집A
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• 제31권2호
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• pp.237-244
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• 2007

In order to obtain mechanical properties of CNT/Polymer nano-composites, molecular dynamics simulation is performed. Overall system was modeled as a flexible unit cell in which carbon nanotubes are embedded into a polyethylene matrix for N $\sigma$ T ensemble simulation. COMPASS force field was chosen to describe inter and intra molecular potential and bulk effect was achieved via periodic boundary conditions. In CNT-polymer interface, only Lennard-Jones non-bond potential was considered. Using Parrinello-Rahman fluctuation method, mechanical properties of orthotropic nano-composites under various temperatures were successfully obtained. Also, we investigated thermal behavior of the short CNT reinforced nanocomposites system with predicting glass transition temperature.

• 한국정보과학회논문지:시스템및이론
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• 제27권3호
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• pp.255-263
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• 2000

다단계 상호 연결망은 대규모 멀티컴퓨터의 대표적인 연결망 구조이다. 브로드캐스트와 멀티캐스트 통신은 캐쉬 관리, 리덕션, 베리어 동기화와 같은 협동 통신을 지원하기 위한 기반 기술이다. 본 논문은 대규모 멀티컴퓨터 시스템을 구성하기에 적합한 웜홀 스위칭하는 양방향 베니언 망에서 동작하는 멀티캐스트 기법을 제안한다. 제안하는 기법은 간단한 하드웨어하에서 교착상태를 일으키지 않고 두 번의 전송 단계를 거침으로써 멀티캐스트와 브로드캐스트를 수행한다. 또한, 원하는 목적 노드의 주소를 큐브로 병합하고, 헤더는 단일 큐브로 인코딩된다. 출력 링크에 경쟁이 발생하면 가장 상위 입력 링크로 부터 들어온 플릿에게 우선 순위를 줌으로써 교착상태를 방지한다. 제안하는 기법을 시뮬레이션을 통해서 통신지연 시간의 관점에서 다른 기법과 비교 평가함으로써 제안하는 멀티캐스트 기법의 성능이 우수함을 보였다. 또한, 제안하는 브로드캐스트 기법은 팬아웃이 $2^m({\geq} {\sqrt{N}}$ 인 최소의 정수, N 은 시스템 크기)인 멀티캐스트의 성능과 유사한 월등한 성능을 낸다는 것을 보였다.

• 수면정신생리
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• 제5권1호
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• pp.103-110
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• 1998

연구배경 : 사지운동증과 수면무호흡증은 공히 연령 증가에 따라 그 유병률이 증가한다. 흥미롭게도, 수면 무호흡증 환자에게 양압술을 시행하면 사지운동증이 증가 또는 유발된다는 보고들이 있다. 그러나 아직 일 관성 있는 결과가 나와있지는 않다. 저자들은 수면무호흡증환자에서 양압술 적용전후의 사지운동지수변화를 살펴보고 이러한 변화에 영향을 끼칠 수 있는 요인들을 밝혀내고자 하였다. 방법 : 야간 수면다원검사 결과 무호흡증으로 진단받았고 사지운동증외의 다른 수면장애가 병발되지 않았던 총 29명(남자 26명, 여자 3명)을 연구대상으로 하였다. 대상군의 평균연령은 $51.6{\pm}10.6$ 세이었다. 결과 : 기본측정일과 양압술 시행일의 사지운동지수는 각각 $5.7{\pm}9.5$회 (범위 0-35.4회), $12.0{\pm}9.2$ 회(범위 0-74.3회)로 양압술 시행일에서 유의하게 증가하였다(p<.05). 전체 대상군을 사지 운동 변화 여부에 따라 분류한 바 사지운동지수 증가군, 무변화군 및 감소군의 수는 각각 10명, 14명, 5명이었다. 사지운동지수 델타값과 연령, 비만 정도, 호흡 관련 변인, 수면구조 관련 변인 델타값 및 양압술 처방압력 과의 상관관계 분석 결과전체 대상군에서는 유의한 상관관계가 나타나지 않았다. 그러나 사지운동지수 증가군에서는 호흡장애지수와 사지운동지수 텔타값 간에 유의한 정상관관계를 보였다(p<.05). 동일군의 다른 변인들이나 다른 군의 제반 변인들에서는 유의한 소견이 나타나지 않았다. 결론 : 본 연구의 결과는 양압술 적용이 직접적으로 사지운동증을 유발하거나 증가시키기보다는 숨어 있거나 적게 판독되었던 사지 운동증을 무호흡의 해소와 함께 표출시킬 가능성을 제시한다.

• 한국어병학회지
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• 제20권3호
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• pp.307-313
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• 2007

In this study, a QCM biosensor was made to detect Edwardsiella tarda (E. tarda) using a specific antibody. A 9 MHz AT-cut piezoelectric wafer layered with two gold electrodes of 5mm diameter had a reproducibility of 0.1 Hz in frequency response and was used as the transducer of the QCM biosensor. Self assembled layer (SAM) was conformed on a quartz crystal by treating with 3-mer-captopropionic acid (MPA) and activated with N-ethyl-N'-(3-dimethyl-aminopropyl) carbodiimide (EDC) and N-hydroxysuccinimide (NHS). The resulting NHS group was further converted to hydrazide by the reaction with hydrazine. Aldehyde group was introduced into the carbohydrate moiety of anti-E. tarda antibody by the reaction with periodic acid and was used to immobilise the antibody through the reaction with hydrazide group on the electrode surface. A baseline was established in the presence of phosphate-buffered saline (PBS) and a resonant frequency (F1) was measured. Sample was added to the sensor surface and second resonant frequency (F2) was measured after unbound substances were washed out with PBS several times. Finally, the frequency shift (ΔF) representing the mass change was calculated by subtracting F2 from F1. After adding the oxidized anti-E. tarda antibody to the electrode surface containing hydrazide group, frequency shift of 288.811.4 Hz (mean S.E) was observed, thus proving that considerable amount of antibody was immobilized. In the immunoassay test, the frequency shift of 1877.75 Hz, 580.67 Hz, 221.39 Hz, 7.671.83 Hz (mean S.E) were observed at doses of 1000, 500, 100, 50 g of bacterial cells, respectively. It was also demonstrated that the prepared sensor chip was stable enough to withstand repeated surface regeneration with 0.2 M Tris-glycine and 1 % DMSO, pH 2.3 more than ten times.

• Molecules and Cells
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• 제21권3호
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• pp.337-342
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• 2006

Interstitial cells of Cajal (ICCs) are pacemaker cells that activate the periodic spontaneous depolarization (pacemaker potentials) responsible for the production of slow waves in gastrointestinal smooth muscle. The effects of vasoactive intestinal polypeptide (VIP) on the pacemaker potentials in cultured ICCs from murine small intestine were investigated by whole-cell patch-clamp techniques. Addition of VIP (50 nM-$1{\mu}M$) decreased the amplitude of pacemaker potentials and depolarized resting membrane potentials. To examine the type of receptors involved in ICC, we examined the effects of the $VIP_1$ agonist and found that it had no effect on pacemaker potentials. Pretreatment with $VIP_1$ antagonist ($1{\mu}M$) for 10 min also did not block the VIP (50 nM)-induced effects. On the other hand exposure to 1H-(1,2,4)oxadiazolo(4,3-A)quinoxalin-1-one (ODQ, $100{\mu}M$), an inhibitor of guanylate cyclase, prevented VIP inhibition of pacemaker potentials. Similarly KT-5823 ($1{\mu}M$) or RP-8-CPT-cGMPS ($10{\mu}M$), inhibitors of protein kinase G (PKG) blocked the effect of VIP (50 nM) on pacemaker potentials as did N-nitro-L-arginine (L-NA, $100{\mu}M$), a non-selective nitric oxide synthase (NOS) inhibitor. These results imply that the inhibition of pacemaker activity by VIP depends on the NO-cGMP-PKG pathway.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2016년도 제50회 동계 정기학술대회 초록집
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• pp.271-271
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• 2016

highly doped N-type 실리콘 기판 위에 극초단 펄스 레이저를 이용하여 LIPSS (Laser-Induced Periodic Surface Structure) 패턴을 형성하였다. 형성된 LIPSS 구조는 $15{\mu}m$와 500 nm 주기를 가지는 ripple로 형성이 되었고 이 구조를 형성하기 위해서 사용된 레이저는 Satsuma HP2, Amplitude syst?mes 이다. LIPSS 패턴을 가지는 기판 위에는 유기반도체 물질인 pentacene을 50 nm로 열 증착방법을 통해 박막을 형성하여 유기박막트랜지스터를 제작하였고, hole mobility를 측정하였다. LIPSS 패턴을 가지는 실리콘 기판과 pristine 실리콘 기판 위의 pentacene의 morphology를 AFM으로 관찰하고 유도된 구조를 연구하였다.