• Title/Summary/Keyword: ${\mu}-CT$

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A Study of Decrease Exposure Dose for the Radiotechnologist in PET/CT (PET-CT 검사에서 방사선 종사자 피폭선량 저감에 대한 방안 연구)

  • Kim, Bit-Na;Cho, Suk Won;Lee, Juyoung;Lyu, Kwang Yeul;Park, Hoon-Hee
    • Journal of radiological science and technology
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    • v.38 no.1
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    • pp.23-30
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    • 2015
  • Positron emission tomography scan has been growing diagnostic equipment in the development of medical imaging system. Compare to 99mTc emitting 140 keV, Positron emission radionuclide emits 511 keV gamma rays. Because of this high energy, it needs to reduce radioactive emitting from patients for radio technologist. We searched the external dose rates by changing distance from patients and measure the external dose rates when we used shielder investigate change external dose rates. In this study, the external dose distribution were analyzed in order to help managing radiation protection of radio technologists. Ten patients were searched (mean age: $47.7{\pm}6.6$, mean height: $165.5{\pm}3.8cm$, mean weight: $65.9{\pm}1.4kg$). Radiation was measured on the location of head, chest, abdomen, knees and toes at the distance of 10, 50, 100, 150, and 200 cm, respectively. Then, all the procedure was given with a portable radiation shielding on the location of head, chest, and abdomen at the distance of 100, 150, and 200 cm and transmittance was calculated. In 10 cm, head ($105.40{\mu}Sv/h$) was the highest and foot($15.85{\mu}Sv/h$) was the lowest. In 200 cm, head, chest, and abdomen showed similar. On head, the measured dose rates were $9.56{\mu}Sv/h$, $5.23{\mu}Sv/h$, and $3.40{\mu}Sv/h$ in 100, 150, and 200 cm, respectively. When using shielder, it shows $2.24{\mu}Sv/h$, $1.67{\mu}Sv/h$, and $1.27{\mu}Sv/h$ in 100, 150, and 200 cm on head. On chest, the measured dose rates were $8.54{\mu}Sv/h$, $4.90{\mu}Sv/h$, $3.44{\mu}Sv/h$ in 100, 150, and 200 cm, respectively. When using shielder, it shows $2.27{\mu}Sv/h$, $1.34{\mu}Sv/h$, and $1.13{\mu}Sv/h$ in 100, 150, and 200 cm on chest. On abdomen, the measured dose rates were $9.83{\mu}Sv/h$, $5.15{\mu}Sv/h$, and $3.18{\mu}Sv/h$ in 100, 150, and 200 cm, respectively. When using shielder, it shows $2.60{\mu}Sv/h$, $1.75{\mu}Sv/h$, and $1.23{\mu}Sv/h$ in 100, 150, and 200 cm on abdomen. Transmittance was increased as the distance was expanded. As the distance was further, the radiation dose were reduced. When using shielder, the dose were reduced as one-forth of without shielder. The Radio technologists are exposed of radioactivity and there were limitations on reducing the distance with Therefore, the proper shielding will be able to decrease radiation dose to the technologists.

The Anti-osteoporosis Effects of Cassia tora L. Seed Ethanol Extract in Ovariectomixed Rats (결명자 주정추출물의 난소적출 랫드에서 항골다공증 효과)

  • Lee, Mu-Jin;An, Byeong-Kwan;Jung, Ho-Kyung;Lee, Ki-Ho;Kim, A-Hyeon;Lee, Hyun-Joo;Jang, Ji-Hun;Sim, Mi-Ok;Kim, Tae-Muk;Kim, Min-Suk;Seong, Tea-Gyeong;Woo, Kyeong-Wan;Cho, Jung-Hee;Kim, Jong-Choon;Cho, Hyun-Woo
    • Korean Journal of Pharmacognosy
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    • v.47 no.4
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    • pp.333-342
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    • 2016
  • In our study, osteoporosis was induced by ovariectomized in female rats, and the prevention and treatment efficacy of the climacteric disease the postmenopausal type I pattern was examined by using the experimental substance Cassia tora (CT) ethanol extracts. Female rats were either sham-operated (sham; n=5) or surgically ovariectomized (OVX; five animals per group) and then administered to OVX control, raloxifene hydrochloride (RLX) 1 mg/kg/day, or CT (20 and 200 mg/kg/day) for 12 weeks. Serum osteocalcin and creatinine concentration were significantly lower in the CT 200 mg/kg/day group compared with the OVX control group. Serum progesterone concentration was significantly higher in the CT 200 mg/kg/day group compared with the OVX control group. Reduction grade of the trabecular bone decreased in the RLX 1 and CT 200 mg/kg/day group compared with that of the OVX control group. In conclusion, CT 200 mg/kg/day may have inhibitory effects on osteoporosis in OVX rats.

Quantitative Analysis of Tooth Mineral Content by High Resolution Micro-computed Tomography

  • Song, Dae-Sung;Kim, Jung-Woo;Hwang, Hee-Su;Oh, Sin-Hye;Song, Ju Han;Kim, Il-Shin;Hwang, Yun-Chan;Koh, Jeong-Tae
    • International Journal of Oral Biology
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    • v.42 no.4
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    • pp.155-161
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    • 2017
  • Teeth and bones are highly mineralized tissues containing inorganic minerals such as calcium phosphate, and a growing number of evidences show that their mineral content is associated with many diseases. Although the quantification of mineral contents by micro-computed tomography(micro- CT) has been used in diagnosis and evaluation for treating bone diseases, its application for teeth diseases has not been well established. In this study, we attempted to estimate a usefulness of a high-resolution micro-CT in analysis of human teeth. The teeth were scanned by using the Skyscan 1172 micro-CT. In order to measure tooth mineral content, beam hardening effect of the machine was corrected with a radiopaque iodine-containing substance, iodoacetamide. Under the maximum resolution of $6.6{\mu}m$, X-ray densities in teeth and hydroxyapatite standards were obtained with Hounsfield unit (HU), and they were then converted to an absolute mineral concentration by a CT Analyzer software. In enamel layer of cusp area, the mean mineral concentration was about $2.14mg/mm^3$ and there was a constant mineral concentration gradient from the enamel surface to the dentinoenamel junction. In the dentin of middle 1/3 of tooth, the mean mineral concentration was approximately $1.27mg/mm^3$ and there was a constant mineral concentration gradient from the outer of root to the pulp side, ranging from 1.3 to $1.06mg/mm^3$. In decay region of dentin, the mineral content was gradually decreased from the intact inner side to the decayed surface. These results suggest that high-resolution micro-CT can be as a useful tool for non-invasive measurement of mineral concentration in teeth.

Patient radiation dose and protection from cone-beam computed tomography

  • Li, Gang
    • Imaging Science in Dentistry
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    • v.43 no.2
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    • pp.63-69
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    • 2013
  • After over one decade development, cone beam computed tomography (CBCT) has been widely accepted for clinical application in almost every field of dentistry. Meanwhile, the radiation dose of CBCT to patient has also caused broad concern. According to the literature, the effective radiation doses of CBCTs in nowadays market fall into a considerably wide range that is from $19{\mu}Sv$ to $1073{\mu}Sv$ and closely related to the imaging detector, field of view, and voxel sizes used for scanning. To deeply understand the potential risk from CBCT, this report also reviewed the effective doses from literatures on intra-oral radiograph, panoramic radiograph, lateral and posteroanterior cephalometric radiograph, multi-slice CT, and so on. The protection effect of thyroid collar and leaded glasses were also reviewed.

A Study on the Establishment of Merging Unit Communication Test System using RTDS based on IEC61850 (RTDS를 이용한 IEC61850 기반 Merging Unit통신 테스트 시스템 구축에 관한 연구)

  • Hong, Jun-Ho;Choi, Myeon-Song;Lee, Seung-Jae;Rim, Seong-Jeong;Park, Dong-Ho
    • Proceedings of the KIEE Conference
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    • 2008.11a
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    • pp.253-255
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    • 2008
  • 병합장치(merging unit: MU)는 변류기(CT)와 변성기(VT)로부터 계측된 전류와 전압을 이더넷을 통해 샘플값(sampled value: SV) 메시지를 전송하는 IED이다. 본 논문에서는 병합장치(MU)의 통신 성능 테스트하기 위한 시스템을 구축하는 방법을 제시하였다. RTDS를 이용하여 계통을 모의하고 샘플값 메시지를 지원하는 과전류계전(OCR) IED를 구축 한 후 계통에 모의 고장을 통해 CB를 동작시킴으로서 성능을 확인하였다. 또한 상용 IED를 연결하여 CB 동작 테스트를 통해 구축한 통신 테스트 시스템의 상호운용성을 확인하였다.

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Traceable AC Voltage and Current Measurements Using Digital Sampling Technique (디지털 샘플링 방법을 사용한 교류전압과 전류의)

  • Wijesinghe, W.M.S.;Park, Young-Tae
    • Proceedings of the KIEE Conference
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    • 2009.07a
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    • pp.686_687
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    • 2009
  • The traceability maintenance system for the AC voltage and current has been developed at the frequency range of 20 Hz to 100 Hz without using any compensation technique which is used at thermal converter (TC) ac-dc transfer system at low frequencies. The system uses a digital voltmeter (DVM) as a data acquisition system of the input waveform and stored data in memory. The developed algorithm acquires and processes the sampling data to calculate the root mean square (rms) value of the input voltage of DVM which operates at DC 10 V range for better accuracy. The best uncertainty of the AC voltage measurements is $3 {\mu}V/V$ within the frequency range. The best uncertainty of the AC current measurements is better than the $5 {\mu}A/A$ and mainly depend on the current to voltage converter, ac-dc current shunt or Current Transformer (CT), used for the measurement

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Effects of Trichosanthes kirilowii Extract against Angiogenesis and Various Tumor Cells' Growth (천화분 추출물이 혈관신생 및 암세포성장에 미치는 영향)

  • Kim, Dong-Woo;Lee, Jong-Hoon;Yoo, Hwa-Seung;Cho, Jung-Hyo;Lee, Yeon-Weol;Son, Chang-Gue;Cho, Chong-Kwan
    • The Journal of Internal Korean Medicine
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    • v.29 no.2
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    • pp.490-499
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    • 2008
  • Objectives : This study was aimed to elucidate the effects of Trichosanthes kirilowii extract (TKE) on the angiogenesis and growth of tumor cells. Methods : Tube formation assay was performed by using human umbilical vein endothelial cells (HUVEC), and anchorage dependent colony assay was performed by using B16-F10 melanoma, Hep G2 and HT1080, CT-26 and SNU-1 cells. Results : For HUVEC, TKE at a level of more than 100 ${\mu}g/m{\ell}$ suppresses cell growth. For HUVEC at 100 ${\mu}g/m{\ell}$ and greater TKE density, the formation of tubes was suppressed in a dose-dependant manner. TKE controls the colony formations of B16-F10 melanoma cells, CT 26 cells, and Hep G2 cells, and its effect is proportional to density. In HT1080 cells and SNU-1 cells, formation is suppressed regardless of density. Conclusions : From these results, it could be concluded that TKE has significant properties on anti-angiogenesis and growth inhibiting of tumor cells. It is suggested that TKE will be a good candidate for new drugs or therapeutics for anti-angiogenesis.

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High Resolution Computerized Tomography System Using the Microfocus X-Ray for Inspection of Small Specimens (소형 물체의 검사를 위한 고해상도 미세 초점 X선 단층 촬영 시스템)

  • Kim, Young-Joo;Koo, Ja-Yong;Lee, Seung-S.;Kim, Whan-W.
    • Journal of the Korean Society for Nondestructive Testing
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    • v.18 no.3
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    • pp.181-190
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    • 1998
  • A computerized tomography system was developed using the X-ray source that has diameter of 5 micrometer. The system is used for the nondestructive testing of specimens with diameter below 20 mm. The convolution back projection algorithm was adopted for the reconstruction of cross sectional image, and the shape of the X-ray beam was let parallel beam or fan beam to compare each resultant image. Our CT system was constructed to operate based on the personal computer. The sectional images of the fabricated specimens were reconstructed and analyzed. The reconstructed images well coincided with real images taken with optical microscope and gave us enough reports on the defects in the ceramic specimen. The resolution of the system regarded as about $20{\sim}30$ micrometers.

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Quantification of the tug-back by measuring the pulling force and micro computed tomographic evaluation

  • Jeon, Su-Jin;Moon, Young-Mi;Seo, Min-Seock
    • Restorative Dentistry and Endodontics
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    • v.42 no.4
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    • pp.273-281
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    • 2017
  • Objectives: The aims of this study were to quantify tug-back by measuring the pulling force and investigate the correlation of clinical tug-back pulling force with in vitro gutta-percha (GP) cone adaptation score using micro-computed tomography (${\mu}CT$). Materials and Methods: Twenty-eight roots from human single-rooted teeth were divided into 2 groups. In the ProTaper Next (PTN) group, root canals were prepared with PTN, and in the ProFile (PF) group, root canals were prepared using PF (n = 14). The degree of tug-back was scored after selecting taper-matched GP cones. A novel method using a spring balance was designed to quantify the tug-back by measuring the pulling force. The correlation between tug-back scores, pulling force, and percentage of the gutta-percha occupied area (pGPOA) within apical 3 mm was investigated using ${\mu}CT$. The data were analyzed using Pearson's correlation analysis, one-way analysis of variance (ANOVA) and Tukey's test. Results: Specimens with a strong tug-back had a mean pulling force of 1.24 N (range, 0.15-1.70 N). This study showed a positive correlation between tug-back score, pulling force, and pGPOA. However, there was no significant difference in these factors between the PTN and PF groups. Regardless of the groups, pGPOA and pulling force were significantly higher in the specimens with a higher tug-back score (p < 0.05). Conclusions: The degree of subjective tug-back was a definitive determinant for master cone adaptation in the root canal. The use of the tug-back scoring system and pulling force allows the interpretation of subjective tug-back in a more objective and quantitative manner.

Removal efficacy and cytotoxicity of a calcium hydroxide paste using N-2-methyl-pyrrolidone as a vehicle

  • Lim, Myung-Jin;Jang, Hyun-Jin;Yu, Mi-Kyung;Lee, Kwang-Won;Min, Kyung-San
    • Restorative Dentistry and Endodontics
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    • v.42 no.4
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    • pp.290-300
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    • 2017
  • Objectives: This study investigated the removal efficacy and cytotoxicity of a newly developed calcium hydroxide paste (cleaniCal, Maruchi) using N-2-methyl-pyrrolidone (NMP) as a vehicle in comparison with ApexCal (Ivoclar Vivadent) and Calcipex II (Nishika), which use different vehicles such as polyethylene glycol and propylene glycol, respectively. Materials and Methods: Thirty maxillary premolars with oval-shaped canals were divided into 3 groups and the teeth were filled with one of the pastes. After removal of the paste, micro-computed tomographic (${\mu}$-CT) imaging was obtained to assess the volume of residual paste in the root canal of each tooth. The teeth were then split longitudinally and the area of the paste-coated surface was evaluated by stereomicroscopy. The cytotoxicity of each product was assessed using an agar overlay assay. The effect of each vehicle on cell viability was evaluated using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The data were analyzed using one-way analysis of variance and Tukey's tests to detect any significance (p < 0.05). Results: In the ${\mu}$-CT and stereomicroscopic analysis, cleaniCal exhibited less remnants of medicament than ApexCal and Calcipex. cleaniCal showed a higher cytotoxicity than the other pastes in the agar overlay assay. Furthermore, NMP exhibited lower cell viability compared to the other vehicles. Conclusions: cleaniCal showed better removal efficacy compared to the other products. However, clinicians should be aware of the higher cytotoxicity of the NMP-based material and consider its possible adverse effects on periradicular tissue when it is overfilled.