• Bulletin of the Korean Chemical Society
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• 제35권3호
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• pp.783-792
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• 2014

The binding interaction between a hemolytic peptide ${\delta}$-lysin and a zwitterionic lipid bilayer POPC was investigated through a series of molecular dynamics (MD) simulations. ${\delta}$-Lysin is a 26-residue, amphipathic, ${\alpha}$-helical peptide toxin secreted by Staphylococcus aureus. Unlike typical antimicrobial peptides, ${\delta}$-lysin has no net charge and it is often found in aggregated forms in solution even at low concentration. Our study showed that only the monomer, not dimer, inserts into the bilayer interior. The monomer is preferentially attracted toward the membrane with its hydrophilic side facing the bilayer surface. However, peptide insertion requires the opposite orientation where the hydrophobic side of peptide points toward the membrane interior. Such orientation allows the charged residues, Lys and Asp, to have stable salt bridges with the lipid head-group while the hydrophobic residues are buried deeper in the hydrophobic lipid interior. Our simulations suggest that breaking these salt bridges is the key step for the monomer to be fully inserted into the center of lipid bilayer and, possibly, to translocate across the membrane.

• 한국정보과학회논문지:컴퓨팅의 실제 및 레터
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• 제10권3호
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• pp.251-258
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• 2004

XMT는 텍스트 형식의 MPEG-4 씬 기술 언어로 방송용 오디오/비디오 편집 및 사용자 중심의 미디어 컨텐츠 개발에 활용될 수 있다. 본 논문에서는 다양한 재생 환경에서 컨텐츠의 상호 교환을 지원하는 XMT 저작 시스템을 제안한다. XMT 저작 시스템은 XMT의 두 가지 파일 포맷인 XMT-$\alpha$와 XMT-$\Omega$를 생성한다. 두 파일 포맷은 같은 객체를 표현하는 방법이 다르므로, 추상화된 XMT-$\alpha$를 위한 저작 인터페이스와 XMT-$\Omega$를 위한 인터페이스를 제공한다. 또한, 두 개의 파일 포맷을 지원할 수 있는 내부 자료 구조를 정의하고, XMT-$\alpha$를 BIFS로 변환하는 기능과 XMT-$\Omega$를 SMIL, XMT-$\alpha$로 변환하는 기능을 제공하여 XMT의 특징인 다양한 환경에서 멀티미디어의 상호 교환성을 제공한다.

• 한국산학기술학회논문지
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• 제16권6호
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• pp.4291-4297
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• 2015

실내공간에서 인간의 쾌적감 및 불쾌적감 등의 감성을 측정하기 위하여 뇌파(EEG)측정을 많이 사용하고 있으나, 뇌파(EEG)측정은 접촉식으로써 실험에 제한적이다. 그러나 진동이미지기술은 웹캠 카메라를 이용하여 인간의 감성을 측정할 수 있는 비접촉식 방법으로써 실내공간에 적용하기에 적합하다고 판단된다. 따라서 인간의 감성을 측정할 수 있는 접촉식인 뇌파(EEG)와 비접촉식인 진동이미지기술의 상관변수를 도출하고자 한다. 본 연구에서는 소리크기 60[dB] 및 90[dB]과 로즈마리 및 쟈스민 향기에 대한 피험자의 뇌파(EEG)와 진동이미지기술의 상관분석을 하였다. 피험자는 건강상태를 점검하여 대학생 남자 3명으로 선별하여 10회 반복 실험하였고, 실험기간은 약 한 달간 진행되었으며, 측정실의 조건은 온도 25[$^{\circ}C$], 상대습도 50[%], 조도 1.000[lux] 및 기류속도 0.02[m/sec]로 하였다. 뇌파(EEG) 23가지 지표(절대${\theta}$, 상대${\theta}$, 절대$S{\alpha}$, 상대$S{\alpha}$, 절대${\alpha}$, 상대${\alpha}$, 절대${\beta}$, 상대${\beta}$, 절대$\gamma$, 상대$\gamma$, 절대$F{\alpha}$, 상대$F{\alpha}$, 절대SMR, 상대SMR, $SMR/{\theta}$, $SMR+M{\beta}/{\theta}$, 절대$H{\beta}$, 상대$H{\beta}$, $H{\beta}/{\alpha}$, 절대$M{\beta}$, 상대$M{\beta}$, SEF50, ASEF50)와 진동이미지기술 10가지 지표(긴장/불안, 억제, 신경과민증, 밸런스, 매력, 자신감, 의심, 스트레스, 공격성, 에너지)를 상관 분석한 결과 뇌파(EEG)의 상대${\gamma}$파와 진동이미지기술의 신경과민증 지표가 (${\pm}$).414와 (${\pm}$).424로 높은 정적상관관계로 분석되었다.

• Journal of applied mathematics & informatics
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• 제26권3_4호
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• pp.673-678
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• 2008

Let $W_{\alpha}$, be a recursively generated quadratically hyponormal weighted shift with a weight sequence ${\alpha}$ : 1, (1, $\sqrt{x}$, $\sqrt{y}$)$^{\wedge}$. In [4] Curto-Jung showed that R = {(x,y) : $W_{1,\;(1,\;{\sqrt{x}},\;{\sqrt{y}})^{\wedge}}$ is quadratically hyponormal} is a closed convex with nonempty interior, which guarantees that there are a lot of quadratically hyponormal weighted shifts with first two equal weights. They suggested a problem computing expressions of certain extremal points of R. In this note we obtain a partial answer of their extremal problem.

• 한국수학교육학회지시리즈B:순수및응용수학
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• 제29권1호
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• pp.93-102
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• 2022

The impact of programming languages in the research sector has helped lot of researchers to broaden their view and extend their work without any limitation. More importantly, even the complex problems can be solved in no matter of time while converting them into a programming language. This convenience provides upper hand for the researchers as it places them in a comfort zone where they can work without much stress. With this context, we have converted the research problems in Topology into programming language with the help of Python. In this paper, we have developed a Python program to find the weaker form of closed sets namely alpha closed set, semi closed set, pre closed set, beta closed set and regular closed set.

• 분석과학
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• 제5권2호
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• pp.191-197
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• 1992

익산군(益山郡) 용제리(龍提里)에서 출토(出土)된 기원전(紀元前)의 세형동검(細形銅劍)을 습식(濕式) 및 원자흡수분광법(原子吸收分光法)으로 조성(組成)을 정량(定量)하였으며, 시편(試片)을 연마(硏磨), 부식(腐蝕)시켜 광학현미경(光學顯微鏡)과 주사형(走査型) 전자현미경(電子顯微鏡)으로 미세구조(微細構造)를 관찰(觀察)하였다. 또한 질량분석계(質量分析計)를 써서 납동위원소비(同位元素比)를 측정(測定)하여 원료(原料)의 산지(産地)를 추정(推定)코자 하였다. 세형동검(細形銅劍)은 Cu-Sn-Pb계(系)로서 Sn이 17%, Pb가 6.8%로서 Sn이 10% 이상이고 Pb가 첨가(添加)된 것으로 보아 청동기(靑銅器) 중기(中期) 이후(以後)임을 알 수 있었다. 시료내부(試料內部)는 ${\alpha}$와 (${\alpha}+{\delta}$) 공정(共晶)으로 되어 있으며 편석(偏析)이 일어나 있었다. 원료(原料)는 중국(中國) 북부산(北部産)일 가능성(可能性)이 크다.

• Journal of Microbiology and Biotechnology
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• 제16권1호
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• pp.20-24
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• 2006

Plasmid DNA (pDNA) is a product of interest for many biopharmaceutical companies and research laboratories, because of increase in the number of gene therapy protocols that use nonviral vectors. This work was undertaken to study the effect of antibiotic and dissolved oxygen concentration (DOC) on the production of a ColE 1-type plasmid (pVAX1-LacZ) hosted in Escherichia coli $DH5\alpha$ and cultured in a batch fermentor with 0.751 of Terrific Broth. A decrease in the DOC from $60\%\;to\;5\%$ was shown to increase the specific pDNA concentration approximately 1.5-fold, due to the downregulation of growth. Additionally, this increase in the pDNA concentration led to a 2.2-fold increase in the purity of cell lysates obtained after cell lysis. However, the use of higher DOC led to 2.8-fold higher volumetric productivity as a consequence of a faster growth rate, reducing the fermentation time from 24 to 8 h. Interestingly, the specific pDNA concentration, and pDNA productivity and purity were always higher $(10-15\%)$ in the absence of antibiotic. Overall, the data indicate that nonselective conditions can be used without compromising yield, productivity, and purity of pDNA.

• 대한치과기공학회지
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• 제34권4호
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• pp.345-352
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• 2012

Purpose: The age-hardening mechanism of an Au-Ag-Cu-Pt-Zn alloy for crown and bridge fabrication was investigated by means of hardness test, X-ray diffraction study and field emission scanning electron microscopic observation. Methods: Before hardness testing, the specimens were solution treated and then were rapidly quenched into ice brine, and were subsequently aged isothermally at $400-450^{\circ}C$ for various periods of time in a molten salt bath and then quenched into ice brain. Hardness measurements were made using a Vickers microhardness tester. The specimens were examined at 15 kV using a field emission scanning electron microscope. Results: By the isothermal aging of the solution-treated specimen at $450^{\circ}C$, the hardness increased rapidly in the early stage of aging process and reached a maximum hardness value. After that, the hardness decreased slowly with prolonged aging. However, the relatively high hardness value was obtained even with 20,000 min aging. By aging the solution-treated specimen, the f.c.c. Au-Ag-rich ${\alpha}_0$ phase was transformed into the Au-Ag-rich ${\alpha}_1$ phase and the AuCu I ordered phase. Conclusion: The hardness increase in the early stage of aging process was attributed to the formation of lattice strains by the precipitation of the Cu-rich phase and then subsequent ordering into the AuCu I-type phase. The decrease in hardness in the later stage of aging process was due to the release of coherency strains by the coarsening of tweed structure in the grain interior and by the growth and coarsening of the lamellar structure in the grain boundary. The increase of inter-lamellar space contributed slightly to the softening compared to the growth of lamellar structure toward the grain interior.

• 대한건축학회논문집:계획계
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• 제34권9호
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• pp.55-66
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• 2018

This study aims to propose color affective model of indoor space by evaluating subjects' physiological responses according to the types of behavioral and affective system. 99 subjects(44 females, 55 males) in their 20s, who had no disorders in visual perception, participated in the experiment. To categorize the subjects based on behavioral and affective system, BAS/BIS scale and Affective scale were used. Color stimuli were composed of five basic colors and three tones: vivid, pale and dull tone of R, Y, G, B, P. For physiological experiment, right and left prefrontal alpha activity was measured to analyze prefrontal EEG asymmetry. Participants were exposed to fifteen color stimuli for 20 seconds each other under the positive and negative emotional condition in a research room with the natural light blocked. The results and conclusion of this study are as follows. Along with factors of behavioral and affective system, cluster analysis was carried out and four types were classified. Type A had high BAS sensitivity, especially high 'drive' trait, and showed high levels of 'anxiety' and 'anger'. Type B had low BAS sensitivity, especially low 'fun seeking' and low 'drive' trait, and showed low levels of 'anxiety' as well as low levels of 'happiness'. Type C had low BIS sensitivity and showed high levels of 'happiness' and low levels of 'sadness'. Type D had high BIS sensitivity and showed high levels of 'lethargy' and 'sadness'. As a result of EEG signal analysis of color stimuli, Type B, Type C, and Type D showed significant differences in prefrontal alpha asymmetry under the negative emotional stimuli. Type B showed more left prefrontal activation in the spaces with pale R and dull G. Type C showed more left prefrontal activation in the spaces with vivid Y and B, pale R, and dull R, G, P. Type D showed more left prefrontal activation in the spaces with vivid Y and P, pale R, Y, P, and dull R, Y, G, B, P. The group of high BAS sensitivity was not influenced by color stimuli under the emotional conditions, whereas the group of high BIS sensitivity was affected by color stimuli under the negative emotional conditions. They showed left prefrontal activation when they were exposed the spaces with vivid, pale, dull tones of Y and P wall.

• 한국실내디자인학회논문집
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• 제23권4호
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• pp.23-31
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• 2014

In this study, in order to analyze customers' space satisfaction, ten modern high-class Korean restaurants, five in New York and another five in Seoul, that were opened or remodeled after 2008 were selected and satisfaction characteristics survey of 197 customers who use these Korean restaurants was conducted by using Likert 5-point scale. The study results(a high reliability was obtained showing the Cronbach's alpha coefficient of average 0.895 for all questions) were analyzed for the frequency, percentage, mean, etc. and the mean between groups were comparatively analyzed by conducting the t-test, Duncan's test by using the SPSS 18.0 statistical program. The results are as follows. First, the results of customers general characteristic comparative analysis, all the Seoul and New York customers have comparatively high academic ability, high income and eating-out expenses. The main customers in Seoul were the women in their thirties and forties while those in New York were mainly in their forties and fifties both men and women at similar rate. Second, as to the satisfaction with the interior, the satisfaction with finishing materials was little higher in New York as Seoul (3.30 points) and New York (3.86 points). The satisfaction with color was relatively higher in Seoul (3.66 points) and relatively lower in New York (3.18 points). As the satisfaction with furniture and decorating accessories was relatively lower in both Seoul (3.10 points) and New York (3.48 points). The satisfaction with space size in Seoul (the total space size: 3.99 points, private space size; 3.90 points) was relatively higher than that in New York (the total space size: 3.46 points, private space size; 3.28 points). The satisfaction with interior and exterior in both Seoul (exterior: 3.63 points, interior: 3.40 points) and New York (exterior: 3.28 points, interior: 3.39 points) were average. For the satisfaction of environment, Seoul (3.42 points) was slightly lower than that of New York (3.56 points). Third, the result of customers' satisfaction in Seoul and New York showed no commonality. Therefore in order to be renewed as the Korean restaurants with high customer satisfaction, it is expected that the Korean restaurants located in Seoul and New York need to plan the space by considering their customers' characteristics and satisfactions.