• Analytical Science and Technology
• /
• v.31 no.6
• /
• pp.232-239
• /
• 2018

Human breast milk (HBM) provides neonates with indispensable nutrition. The present study evaluated the anti-cancer activity of diluted and pasteurized early HBM (< 6 weeks' lactation) on human breast cancer cell lines. The cell lines MCF7 and MDA-MB231 were exposed to 1 % HBM from the 1st, 3rd, and 6th weeks of lactation and exhibited reduced proliferation rates. As controls, breast cell lines (293T and MCF-10A), breast cancer cell lines (MCF-7 and MDA-MB-231), and $CD133^{hi}CXCR4^{hi}ALDH1^{hi}$ patient-derived human cancer stem-like cells (KU-CSLCs) were treated with prominent milk proteins ${\beta}$-casein, ${\kappa}$-casein, and lactoferrin at varying doses (10, 50, and $100{\mu}g$) for 24 or 48 hrs. The impact of these proteins on cell proliferation was investigated. Breast cancer cell lines treated with ${\kappa}$-casein and lactoferrin exhibited significantly reduced viability, in both a dose- and time-dependent manner. Interestingly, ${\kappa}$-casein selectively impacted only cancer (but not normal breast) cell lines, particularly the more malignant cell line. However, ${\beta}$-casein-exposed human breast cancer cell lines exhibited a significantly higher proliferation rate. Thus, ${\kappa}$-casein and lactoferrin appear to exert selective anti-cancer activities. Further studies are warranted to determine the mechanisms underlying ${\kappa}$-casein- and lactoferrin-mediated cancer cell-selective cytotoxic effects.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.21 no.7
• /
• pp.233-243
• /
• 2020

This study determined the relationship between organizational conflicts and job satisfaction of administrative staff members employed in university hospitals. The sample consisted of 232 hospital administrators working at four different college hospitals located in D city. The survey was conducted using a self-administered questionnaire during the period from January 10th 2019 to February 15th 2019. As a result of the study, the job satisfaction levels were significantly different according to age, education, BMI, subjective sleep evaluation, subjective health status, job position, monthly income, physical burden of work, sense of satisfaction at work, fit to the job and consideration to quit the job. The job satisfaction levels according to the organizational conflicts were significantly lower with higher organizational conflicts. Further, the job satisfaction level showed a significant negative correlation with organizational conflicts. The risk ratio of lower job satisfaction significantly increased for the group with higher organizational conflict scores than that of the group with lower organizational conflict scores. The results suggest that job satisfaction of administrative staff at university hospitals is significantly related with organizational conflicts. It is necessary to present specific measures to resolve conflicts within an organization in order to enhance job satisfaction for administrative staff at university hospitals.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.17 no.7
• /
• pp.103-111
• /
• 2016

To provide baseline data for interventions to improve nursing students' satisfaction with their major, this descriptive correlational study analyzed the relationships among emotional intelligence, critical thinking, and major satisfaction. To set up the research data, questionnaires were collected from 232 nursing students in 3 nursing colleges of cities K and B from May 15th, 2014 to June 15th, 2014. SPSS 21.0 was used to analyze the data for the descriptive statistics, t-test, ANOVA, Scheffe's test, and Pearson correlation coefficients. The results are as follows. First, the mean scores of emotional intelligence (4.93), critical thinking (3.43), and major satisfaction (3.76) were above the moderate level but showed significant differences according to gender, grades, and motivations for choosing the major and challenges in college life. Positive correlations were observed among emotional intelligence, critical thinking, and major satisfaction Therefore, when designing an intervention program to improve the major satisfaction, it is recommended to consider a plan that enables them to develop emotional intelligence and critical thinking.

• Journal of Digital Convergence
• /
• v.18 no.8
• /
• pp.361-370
• /
• 2020

The purpose of this study was to identify factors affecting nursing professionalism in students and develop educational programs. Data were collected from 169 students in G-do, from March 15th to April 30th, 2019. Analysis was done using IBM SPSS 21.0 for frequency, percentage, average, standard deviation, t-test, ANOVA, Pearson correlation coefficient, and Multiple regression. The subjects' moral self was 3.39, moral behavior was 3.72, self-control was 3.68, empathy was 3.53, interpersonal competence was 3.69, and nursing professionalism was 3.90. Nursing professionalism positively correlated with self-control, empathy, and interpersonal competence. The most important factor affecting nursing professionalism was major satisfaction - 'satisfied' (β=.232, p=.002), followed by empathy (β=.222, p=.003) and interpersonal competence (β=.178, p=.016). The explanatory power was 18.5% (F=13.69, p<.001). Therefore, a program promoting major satisfaction, empathy, and interpersonal competence and a customized program considering personality and department adaptation are needed for establishment and enhancement of nursing professionalism. Utilizing the results of this study as basic data for nursing professionalism enhancement program and study confirming enhancement is expected.

• Journal of Conservation Science
• /
• v.34 no.6
• /
• pp.481-492
• /
• 2018

We conducted TL/OSL dating for the earthenware kilns in the Bongsan-ri archaeological site, Osong, which was occupied from the late nineteenth to the late twentieth century. With the SAR-TL/OSL method, paleodose was determined from the equivalent dose during the burial period($ED_{burial}$), the background dose($ED_{BG}$), the fading correction factor(f), and the overestimation correction factor(C). The annual dose rates and their provenance were evaluated from the measurement of natural radionuclides $^{238}U$, $^{232}Th$, and $^{40}K$. Because the comprehensive absolute age was provided by combining the resulting TL/OSL and radiocarbon data, we concluded that, for the absolute chronology of a modern archaeological site, TL/OSL dating and radiocarbon dating must be carried out together and summed. The construction and occupation of earthenware kilns in the Bongsan-ri site had changed from stage I (No.5, 6 kilns), to stage II (No.1, 2, 3 kilns), to stage III (No.4) in chronological order. When Bayesian statistics were applied, we found that the absolute ages of occupation for stages I, II, and III correspond to AD $1910{\pm}23$, AD $1970{\pm}10$, and AD $1987{\pm}4$. These results were in good agreement with the archaeological context or chronology.

• Journal of Internet of Things and Convergence
• /
• v.7 no.1
• /
• pp.79-89
• /
• 2021

This study attempted to identify the information gap about Internet of Things (IoT) devices and services in the era of digital transformation. To this end, we analyzed differences in perception of predicting future issues about IoT devices and services, and analyzed differences in the need for digital technology and help in life according to perceptions and experience of using IoT devices and services. Also, the level of education and demand for education were analyzed. A survey was conducted from February 15th to March 7th, 2021 for residents in Gwangju Metropolitan City and Jeollanam-do, and 232 respondents responded. Analysis was performed using SPSS 21.0, and all statistical values were presented as average values. The results of the study are as follows. First, the future issues of the intelligent information society according to the recognition of the intelligent information society, the help of life provided by artificial intelligence devices and services, and the need for intelligent information technology were presented. Second, the difference in Life help provided by artificial intelligence according to the recognition and use experience of artificial intelligence devices was presented. Third, the difference in life help provided by artificial intelligence according to the recognition and use experience of artificial intelligence service was presented. Fourth, the difference in necessity according to artificial intelligence technology recognition and use experience was presented. Fifth, the educational level and educational demand of the intelligent information society were investigated and presented. Through the results of this study, a suggestion for resolving the information gap in the era of digital transformation was suggested.

• Journal of Radiation Protection and Research
• /
• v.47 no.1
• /
• pp.16-21
• /
• 2022

Background: Epidemiological observations such as mental retardation, physical deformities, etc., in children besides different types of cancer in the adult population of the Malwa region have been reported. The present study is designed to get insight into the role of naturally occurring radioactive material (NORM) in causing detrimental health effects observed in the general population of this region. Materials and Methods: Deep soil samples were collected from different locations in the Malwa region. Their activity concentrations were determined using low-level background gammaray spectrometry. High efficiency and high purity germanium detector capped in a lead-shielded chamber having a resolution of 1.8 keV at 1,173 keV and 2.0 keV at the 1,332 keV line of ⁶⁰Co was used in the present work. Data were evaluated with Genie-2000 software. Results and Discussion: Mean activity concentrations of ²³⁸U, ²³²Th, and ⁴⁰K in deep soil were found to be 101.3 Bq/kg, 65.8 Bq/kg, and 688.6 Bq/kg, respectively. The mean activity concentration of ²³⁸U was found to be three and half times higher than the global average prescribed by the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR). It was further observed that the activity concentration of ²³²Th and ⁴⁰K has a magnitude that is nearly one and half times higher than the global average prescribed by UNSCEAR. In addition, the radioisotope ¹³⁷Cs which is likely to have its origin in radiation fallout was also observed. It is postulated that the NORM present in high quantity in deep soil somehow get mobilized into the water aquifers used by the general population and thereby causing harmful health problems. Conclusion: It can be stated that the present work has been able to demonstrate the use of low background gamma-ray spectrometry to understand the role of NORM in causing health-related effects in a general population of the Malwa region of Punjab, India.

• Korean Journal of Heritage: History & Science
• /
• v.51 no.2
• /
• pp.170-203
• /
• 2018

From the period of Japanese colonialism up to the present, the researchers of archaeology and ancient history in Korea and Japan have paid much attention to the Honam area. Recently the ruins and relics of Wae lineage are often discovered at archaeological excavation sites in this region. In particular, at least 17 keyhole-shaped mounds were confirmed. The fact that three mounds were built on one site was newly revealed. Haniwa, a representative earthenware object of the Kofun period in Japan, was discovered as well. Therefore, the study of a historical meaning of archaeological materials about Wae lineage in the Honam area thus far must be reexamined. The ruins and relics of Wae lineage in the Honam area have been studied by selecting only specific cases. I identified all the ruins and relics of Wae lineage in the Honam area and analyzed the process of their change in this paper. I reviewed the relationship between Wae and Mahan, and the purpose of their negotiation based on archaeological characteristics, changing processes, and historical records on a quarterly basis. The ruins and relics of Wae lineage have increased and widely spread since the early period of the 5th century in the Honam area. This tendency continued until the late period of the 6th century. Weapons of Wae lineage were introduced and tombs in the style of Wae were built from the late 4th century to the early period of the 5th century (TG232~TK216 period). Sueki was introduced from the middle to late period of the 5th century (TK208~TK23 period). Keyhole-shaped mounds and tombs in the style of Wae were built from the late period of the 5th century to the early period of the 6th century (TK47~MT15 period). Japanese weapons were introduced from the middle to late period of the 6th century (TK10~TK209 period). In other words, the archaeological appearance is different in each quarterly period. There was an intensive diplomatic relationship between Baekje and Wae in the TG232~TK216 period. The military might be included in a mission of Wae. The materials of Wae lineage of this period are likely to be related to this. Sueki spread to the inland part of the Honam area in the TK208~TK23 period. This Sueki tends to be excavated on advantageous sites for the accumulation and distribution of supplies. The main characters of the keyhole-shaped mounds are presumed to be a group of traders which were under the control of a certain influence in the north of Kyushu. The keyhole-shaped mounds were abruptly built at some distance from mounds of the leaders in the Honam area. Additionally, there was no special influence base to which the characters of the keyhole-shaped mounds belonged in the surroundings. However, it might have been impossible for the group of traders to build the keyhole-shaped mounds without the support from the residents at all because there was a big difference in the building technology of the keyhole-shaped mounds between Japan and the Honam area. The time of building some keyhole-shaped mounds is the same or almost the same with that of the mounds built for the regional leaders. This proves a close relationship with the residents as well. What do the archaeological materials of Wae lineage which have been used and buried mean over 200 years in the Honam area? Geumgwan Gaya, which had exported iron resources to Japan, perished in the early period of the 5th century. Instead of Gaya, the Honam area might have played an important role to supply the necessary resources to Japan. We assume that the Japanese (Wae) actively worked to acquire various resources focusing on the underground resources in the Honam area.

• Journal of the Mineralogical Society of Korea
• /
• v.23 no.4
• /
• pp.347-356
• /
• 2010

Bauxite is a main raw material for the production of alumina and aluminum hydroxide in the processing plant of KC company. It is a NORM (Naturally Occurring Radioactive Materials), and its waste, red mud, is a TENORM (Technologically Enhanced Naturally Occurring Radioactive Materials). The purpose of the geochemical and mineralogical investigations of the bedrock and soils in and around the plant, a large NORM source, was to provide basic data for measuring the radiation dose and protecting from radioactive hazards. Soils were mixtures of minerals derived from the country rock (quartz, feldspar, mica, kaolin, gibbsite, and sepiolite) and bauxite (hematite, boehmite, and calcite) of open-air storage. Average U and Th contents of the soil samples were 4.7 ppm and 23 ppm, respectively, indicating somewhat Th anomaly. The average concentrations of radionuclides are $^{40}K$ 100~1,433 Bq/kg, $^{226}Ra$ anomaly in the red mud open-air storage. Soil external hazard indices range from 0.10 to 1.66 with an average of 0.63. Although most of the indices are below 1.0 that is a regulation value, those of 4 samples of total 41 soil samples exceed 1.0, requiring further detailed investigation.

• Food Science and Preservation
• /
• v.6 no.2
• /
• pp.228-232
• /
• 1999

Total acidities were incereased gradually during fermentation. Total acidities of vinegars which fermented from sweet and astringent persimmon were 5.95 and 5.81% at 8th day of acetic acid fermentation, respectively. Hunter's color values were not significant difference during alcohol fermentation and acetic acid fermentation. Browning incereased continuously during alcohol fermentation whereas browning and turbidity decreased continuously during acetic acid fermentation. The browning and turbidity of vinegar which fermented from sweet persimmon was higher than those of vinegar which fermented from astringent persimmon. The contents of total tannin were 2.40 and 6.44mg/ml at the initial fermentation of sweet and astringent persimmon respectively. But in contents decreased continuously during fermentation. Reducing and total sugar contents decreased continuously during fermentation. At 5th day of acetic acid fermentation, contents of reducing and total sugar were 5.0 and 8.5mg/ml in sweet persimmon and 2.8 and 2.9mg/ml in astringent persimmon respectively.