• Communications for Statistical Applications and Methods
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• v.7 no.2
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• pp.541-548
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• 2000

Various statistical methods for assessment of equivalence in average bioavailabilities have been developed under the assumption that the intra-subject variabilities for the test and reference formulations are the same. Without the assumption, assessing the equivalence in average bioavailabilites does not imply that the two formulations are therapeutically equivalent and exchangeable. The most commonly used test procedure for equality of variabilites in 2$\times$2 crossover experiment is the so called Pitman-Morgan's adjusted F test based on the model without carryover effects (Chow and Liu(1992)). In this paper, a Bayesian method based on the Intrinsic Bayes Factor is proposed, which can be applied to the model with carryover effects.

• Natural Product Sciences
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• v.8 no.3
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• pp.94-96
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• 2002

Four hundred varieties of plant extracts were screened for inhibitory activity against the NFAT transcription factor which plays an important role in inducing immune response. Among them, the MeOH extract of Cnidium officinale showed potent activity, and the activity-guided separation yielded butylidenephthalide, senkyunolide A and falcarindiol as the active constituents. The $IC_{50}$ value of butylidenephthalide was $1.3{\times}10^{-4}\;M$ and was similar to that of senkyunolide A $(2.1{\times}10^{-4}\;M)$. Interestingly, falcarindiol showed higher activity $(IC_{50},\;2.6{\times}10^{-5}\;M)$ than the two phthalides.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2011.07a
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• pp.475-478
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• 2011

율-왜곡 최적화 기법을 통한 화면내 예측 모드 결정 방법은 부호화 효율이 높지만 복잡도가 크다. 본 논문에서는 H.264/AVC의 율-왜곡 값의 특성을 분석하여 율-왜곡 최적화 기법에 사용되는 예측 모드의 후보를 줄임으로써 보다 빠른 휘도 화면내 $4{\times}4$ 예측 모드 결정 방법을 제안한다. 제안된 방법은 균일한 차분 블록값을 가지는 예측 모드와 균일하지 않은 차분 블록값을 가지는 예측 모드의 통계적 분석을 통해 부호화 속도를 향상시킨다. H.264/AVC의 참조 소프트웨어 JM 14.2와 비교하여 0.04[dB]라는 무시할 수 있는 PSNR의 손실을 가지면서도 0.3[%]의 비트율 절약과 19.6[%]의 부호화 속도 향상을 가져왔다.

• Proceedings of the KSME Conference
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• 2000.11b
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• pp.118-123
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• 2000

This experimental study was conducted to figure out the characteristics of convective heat transfer in non boiling vertical downward flow with polymer additives. This experiment was studied in 26mm diameter, 800mm heating length and $1{\times}10^5W/m^2$ heat flux. The polymer concentration ranged from 0PPM to 500PPM with corresponding from Reynolds number $3.3{\times}10^4$ to $6.8{\times}10^4$ in non boiling vertical downward flow. Experimental results show that the characteristics of convective heat transfer was a strong function of polymer concentration and it has decreased with increasing the polymer concentration in non boiling vertical downward flow.

• Proceedings of the Earthquake Engineering Society of Korea Conference
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• 2005.03a
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• pp.345-352
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• 2005

The purpose of this study is to analyze the stress-strain behavior of confined concrete columns with rectangular section. Uniaxial concentric loading tests of nineteen concrete columns with rectangular section ($150{\times}100$, $250{\times}100$, $350{\times}100\;mm$) were conducted. The main variables are transverse reinforcement volumetric ratio and spacing, cross tie arrangement, cross-section aspect ratio, and concrete strength. From the present experiments, it was found that the increase of transverse reinforcement ratio increases the maximum stress and ductility ratio and the reduction of the spacing of transverse reinforcement also increases the ductility and effective confinement. The increase of the aspect ratio of the cross-section does not influence much the stress-strain behavior of rectangular columns within the aspect ratio range of 3.5. The effect of concrete strength on ductility is also discussed.

• Journal of the Korean Statistical Society
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• v.35 no.3
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• pp.239-250
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• 2006

A $2{\times}2$ crossover design including carryover effect is considered for assessment of population bioequivalence of two drug formulations in a Bayesian framework. In classical analysis, it is complex to deal with the carryover effect since the estimate of the drug effect is biased in the presence of a carryover effect. The proposed method in this article uses uninformative priors and vague proper priors for objectiveness of priors and the posterior probability distribution of the parameters of interest is derived with given priors. The posterior probabilities of the hypotheses for assessing population bioequivalence are evaluated based on a Markov chain Monte Carlo simulation method. An example with real data set is given for illustration.

• The Journal of Korean Society for School & Community Health Education
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• v.21 no.1
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• pp.1-14
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• 2020

Objectives: The purpose of this study is to analyze the relationship between dual smoking and mental health. Methods: This study was conducted on 5,879 Korean adults, and a logistic regression analysis was conducted to investigate the relationship between smoking type and mental health. Results: The types of smoking were surveyed as 'dual smoking' 6.1%, 'electronic cigarette' 1.7%, 'general smoking' 12.1%, and 'non-smoking' 80.1%.. The risk of diagnosing depression in the dual smoking group was 2.87 times higher than in the non-smoking group, the risk of depression was 1.66 times higher than in the non-smoking group, and the risk of stress was 1.62 times higher. Conclusion: Even in adulthood, health education such as smoking prevention education and smoking cessation education should be conducted.

• Journal of Broadcast Engineering
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• v.15 no.6
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• pp.815-829
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• 2010

In this paper, we propose a new $4{\times}4$ intra coding method by unidirectional prediction for improvement of intra-frame coding efficiency of H.264/AVC. There are $4{\times}4$, $8{\times}8$, and $16{\times}16$ intra prediction modes in the current H.264/AVC. For the $4{\times}4$ intra prediction, coding efficiency is achieved by accurate prediction with small block size in relatively complicated regions, and the $16{\times}16$ intra prediction method can predict more accurately compared to $4{\times}4$ intra prediction with only one directional information in relatively homogeneous regions. We propose a unidirectional $4{\times}4$ intra prediction method adopting a small-size prediction and one directional prediction approaches. In order to improve coding efficiency, the proposed method is conducted by $4{\times}4$ block and their prediction directions are all the same, resulting that we need to send only one directional information for each macroblock. For intra-frame coding setting, we achieve 10.47% and 1.57% coding efficiency in BD-bitrate for only $16{\times}16$ intra mode and $4{\times}4$, $16{\times}16$ intra mode, respectively.

• Transactions of the Korean hydrogen and new energy society
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• v.19 no.6
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• pp.529-536
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• 2008

Cyanobacteria Synechocystis PCC 6803 or the extracted thylakoid membrane from this strain was appled to photosynthetic bio-electrochemical fuel cell(PBEFC) for the production of hydrogen under the illumination of 48Klux using halogen lamp. PBEFC was composed of anode, cathode and membrane between them. Electrode material was carbon paper while electron mediator and receptor were added phenazine methosulfate(PMS) and potassium ferricyanide respectively. When water and 50 mM tricine buffer and $300{\mu}M$ PMS were added to the anode under the light condition, PBEFC produced the current density $4.4{\times}10^{-5}\;mA/cm^2$, $1.4{\times}10^{-4}\;mA/cm^2$ and $2.4{\times}10^{-4}\;mA/cm^2$, respectively. And the addition of the thylakoid membrane to the system increased current density to $1.3{\times}10^{-3}\;mA/cm^2$. Two times increase of the thylakoid membrane into the anode doubled the current density to $2.6{\times}10^{-3}\;mA/cm^2$. But the current density was not increased proportionally to the amount of thylakoid membrane increased. The system was unstable to measure the electricity output due to the foam production in the anode. Addition of triton X-100 and tween 80 stabilized the system to measure the electricity output but the current density was not increased higher than $8.4{\times}10^{-4}\;mA/cm^2$ and $2.3{\times}10^{-3}\;mA/cm^2$. When the thylakoid membrane was substituted to Synechocystis PCC 6803 cells of four-day culture which has chlorophyll contents $20.5{\mu}g/m{\ell}$, maximum current density was $1.3{\times}10^{-3}\;mA/cm^2$ with $1\;k{\Omega}$ resistance.

• Progress in Medical Physics
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• v.25 no.1
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• pp.15-22
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• 2014

The IMRT is proper implement to get high dose deliver to tumor as its shape and selective approach in radiation therapy. Since the IMRT is performed as modulated the radiation fluence by the MLC created the open shapes and its irradiation time, the dose of segment of radiation field effects on the cumulated portal dose. The accurate output factor of small and step shape of segment is important to improve the determination of deliver tumor dose as it is directly proportional to dose. This experiment performed with the 6 MV photon beam of Clinac Ex(Varian) from $3{\times}3cm^2$ to $0.5{\times}0.5cm^2$ small field size for collimator jaw in MLC free and/or for MLC open field in fixed collimator jaw $10{\times}10cm^2$ using the CC01 ion chamber, SFD diode, diamond detector and X-Omat film dosimetry. As results of normalized to the reference field of $10{\times}10cm^2$ of MLC, the output factor of $3{\times}3cm^2$ showed $0.899{\pm}0.0106$, $0.855{\pm}0.0106$ for $2{\times}2cm^2$, $0.764{\pm}0.0082$ for $1{\times}1cm^2$ and $0.602{\pm}0.0399$ for $0.5{\times}0.5cm^2$. The output factor of MLC open field has shown a maximum 3.8% higher than that of the collimator jaw open field.