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Development of the Experimental Apparatus to Measure a Pore Size of Micro-pore Fabrics Used for a Bedding to Block the House Dust Mite Allergen

집먼지 진드기 알레르겐 차단 침구에 사용되는 극세 공극 직물의 공극 측정을 위한 입자 투과 실험 장치의 개발

  • Kim, Donhue (Department of Biochemical Engineering, Dongyang Mirae University)
  • 김동회 (동양미래대학교 생명화학공학과)
  • Received : 2022.07.01
  • Accepted : 2022.07.06
  • Published : 2022.11.01

Abstract

In order to measure the allergen penetration of micropore fabrics, it is necessary to develop a convenient and appropriate experimental method for measuring a pore size of micropore fabrics. In this study, a simple and economical experimental apparatus was developed for the analysis of the pore size of micropore fabrics by measuring the weight reduction rate. In addition, the allergen blocking properties was evaluated by measuring the pore sizes of various fabrics. According to this study, the size of the pores of the microporous fabric could be obtained by measuring the weight reduction rates. In addition, higher weight reduction rate was obtained as the suction pressure passing through the particle permeation device decreased and the suction time was increased. It is expected that the developed experimental method and apparatus can be utilized as an experimental standard for quality control methods to verify the effectiveness of micropore fabrics used for house dust mite blocking bedding.

극세 공극 직물의 알레르겐 투과율을 측정하기 위해서는 극세 공극 직물의 공극을 측정하는 편리하고 적절한 실험 장치의 연구 개발이 필요하다. 본 연구에서는 중량 감소율을 측정하여 극세 공극 직물의 공극 크기를 측정하기 위한 간단하고 경제적인 실험 방범을 개발하였다. 또한, 개발된 미세 입자 투과 장치를 사용하여 다양한 직물의 공극 크기를 측정하여 알레르겐 차단 성능을 평가하였다. 본 연구에 의하면 극세 공극 직물의 공극의 크기는 중량 감소 비율을 측정함으로써 구할 수 있었다. 또한 중량 감소 비율의 값은 입자 투과 장치를 통과하는 흡입 압력이 작을수록, 흡입 시간이 길수록 큰 값을 나타났으며, 이 값으로부터 직선 삽입 방법을 통하여 실험 직물의 공극 크기를 측정 할 수 있었다. 개발된 실험 장치 및 방법은 집먼지 진드기 차단 침구에 사용되는 극세 공극 직물에 대하여 그 효과를 검증하는 품질 관리 방법의 실험 기준으로 사용될 수 있을 것으로 기대된다.

Keywords

Acknowledgement

본 연구는 동양미래대학교의 학술 연구 지원으로 수행되었습니다.

References

  1. Voorhost, R., Spieksma, F. T. M., Varekamp, H., Leupen, M. J. and Lyklema, A. W., "The House Dust Mite (Dermatophagoides Pteronyssinus) and the Allergen Produces, Identify with the House-Dust Allergen," J. Allergy, 39, 325-339(1967). https://doi.org/10.1016/0021-8707(67)90045-7
  2. Dowse, G. K., Tuner, K. J., Stewart, G. A., Alpers, M. P. and Woolcock, A. J., "The Association between Dermatophagoides Mite and the Increasing Prevalence of Asthma in Village Communities Within the Papua New Guinea highland," J. Allergy Clin Immunol., 75, 75-83(1985). https://doi.org/10.1016/0091-6749(85)90016-8
  3. Voorhost, R., Spieksma-Boezeman, M. I. A. and Spiekma, F. T. M., "Is a Mite (Dermatophagoides sp.) the Producer of the House Dust Allegen," Allergy Asthma, 10, 329-334(1964).
  4. Platts-Mills, T. A. E. and de Week, A. L., "Dust Mite Allergens and Asthma- a Worldwide Problem," J. Allergy Clin Immunol., 83, 416-427(1989). https://doi.org/10.1016/0091-6749(89)90128-0
  5. Heyman, P. W., Chapman, M. D. and Platts-Mills, T. A. E., "Antigen Der f 1 from the Dust Mite Dermatophagoides farinae; Structural Comparision with Der p 1 from Dermatophagoides pteronyssius and Epitope Specificity of Murine IgG and Human IgG Antibodies," J. Immunol., 137, 2841-2847(1986). https://doi.org/10.4049/jimmunol.137.9.2841
  6. Biloitti, G., Passaleva, A., Romagnani, S. and Ricci, M., "The Environmental Influence on Childhood Asthma," Clin Allergy, 2, 109-113(1972). https://doi.org/10.1111/j.1365-2222.1972.tb01275.x
  7. Min, K. Y., Kim, Y. Y. and Kang, S. Y., "An Epidemiologic Study on Inhalant Allergens in Perennial Allergic Rhintis," J. Asthma Allergy Clin Immnol., 2, 78-85(1983).
  8. Buchana, D. J. and Jones, I. G., "Allergy to House Dust Mites in the Tropics," Brit. Med. J., 3, 764(1972).
  9. Tovey, E. and Marks, G., "Methods and Effectiveness of Environmental Control," J. Allergy Clin Immnol., 103, 179-191(1999). https://doi.org/10.1016/S0091-6749(99)70488-4
  10. Brantley, J. and Martin, J. "Integrity Testing of Sterilizing-Grade Filters," Genet. Eng. News, 17, 24(1997).
  11. Emory, S. F., "Principles of Integrity-Testing Hydrophilic Microporous Menbrane Filters," Part I. Pharm. Technol., 13, 68-77(1989).
  12. Hofmann, F., "Integrity Testing of Microfiltration Membranes," J. Parenteral Sci. Technol., 38, 148-158(1984).
  13. Schroeder, H. G. and DeLuca, P. P., "Theoretical Aspects of Sterile Filtration and Integrity Testing," Pharm. Technol., 4, 80-85(1980).
  14. Olson, W. P., Martinez, E. D. and Kern, C. R., "Diffusion and Bubble-Point Testing of Microporous Cartridge Filters: Preliminary Results at Production Facilities," J. Parenteral Sci. Technol., 35, 215-222(1981).
  15. Johnston, P. R., Lukaszwicz, R. C. and Meltzer, T. H., "Certain Imprecisions in the Bubble-Point Measurement," J. Parenteral Sci. Technol., 35, 36-39(1981).
  16. Kim, D., "A Study for the Effects of Fine Gap Fabric Bedding on the Levels of Dust and House Dust Mite Allergens," Korean Chem. Eng. Res., 43, 136-139(2005).
  17. Beltrani, V. S., "The Role of House Dust Mites and Other Aeroallergens in Atopic Dermatitis," Clin Dermatol., 21, 177-182(2003). https://doi.org/10.1016/S0738-081X(02)00366-8
  18. Hewitt, N., Barrow, G. L., Miller, F., Turk, F. and Turk, S., "Mites in the Personal Environment and Their Role in Skin Disorders," Brit. J. Derm., 89, 401-409(1973). https://doi.org/10.1111/j.1365-2133.1973.tb02995.x
  19. Helson, G. A. H., "House-dust Mites and Possible Connection with Sudden Infant Death Syndrome," N Z Med. J., 74, 209(1971).
  20. Kim, D., "A Study on the Thermo-pressing Sewing Method for Prevention of Allergen Penetration Through Micropore Fabric," Korean J. Chem. Eng., 35, 1680-1686(2018). https://doi.org/10.1007/s11814-018-0065-1