YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
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Ameliorating Effect of Herbal Extracts Mixtures of Laurus nobilis, Rosa roxburghii and Opuntia ficus indica on Ethanol Induced Psychomotor Alterations in Rats

흰쥐에서 월계수, 자리, 백년초 혼합물에 의한 숙취완화 효과

  • Kim, Hee Jin (Uimyung Research Institute for Neuroscience, Department of Pharmacy, Sahmyook University) ;
  • dela Pena, Irene Joy I. (Uimyung Research Institute for Neuroscience, Department of Pharmacy, Sahmyook University) ;
  • Yoon, Seo Young (Uimyung Research Institute for Neuroscience, Department of Pharmacy, Sahmyook University) ;
  • de la Pena, Jun Bryan (Uimyung Research Institute for Neuroscience, Department of Pharmacy, Sahmyook University) ;
  • Paek, Se Hee (Food R&D Center, CJ CHEILJEDANG) ;
  • Seo, Yong Ki (Food R&D Center, CJ CHEILJEDANG) ;
  • Park, Seok Jun (Food R&D Center, CJ CHEILJEDANG) ;
  • Moon, Byoung Seok (Food R&D Center, CJ CHEILJEDANG) ;
  • Cheong, Jae Hoon (Uimyung Research Institute for Neuroscience, Department of Pharmacy, Sahmyook University)
  • 김희진 (삼육대학교 약학대학 의명신경과학연구소) ;
  • ;
  • 윤서영 (삼육대학교 약학대학 의명신경과학연구소) ;
  • ;
  • 백세희 ((주)CJ 제일제당 식품연구소) ;
  • 서용기 ((주)CJ 제일제당 식품연구소) ;
  • 박석준 ((주)CJ 제일제당 식품연구소) ;
  • 문병석 ((주)CJ 제일제당 식품연구소) ;
  • 정재훈 (삼육대학교 약학대학 의명신경과학연구소)
  • Received : 2014.10.13
  • Accepted : 2014.12.15
  • Published : 2014.12.31
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Abstract

The aim of this study was to find optimal ratio of herbal extracts to ameliorate ethanol-induced psychomotor alterations. Four mixtures of Laurus nobilis (L. nobilis), Rosa roxburghii (R.R.) and Opuntia ficus indica (OFI) were pretreated 30 minutes before ethanol administration in rats. Behavioral activities were evaluated. Blood ethanol and acetaldehyde levels were also measured. These effects of mixture of R.R (50 mg/kg)+OFI (100 mg/kg)+L.nobilis (100 mg/kg) were better than those of other mixtures. This mixture could be used as an effective substance to develop a functional food.

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