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http://dx.doi.org/10.17480/psk.2014.58.6.364

Ameliorating Effect of Herbal Extracts Mixtures of Laurus nobilis, Rosa roxburghii and Opuntia ficus indica on Ethanol Induced Psychomotor Alterations in Rats  

Kim, Hee Jin (Uimyung Research Institute for Neuroscience, Department of Pharmacy, Sahmyook University)
dela Pena, Irene Joy I. (Uimyung Research Institute for Neuroscience, Department of Pharmacy, Sahmyook University)
Yoon, Seo Young (Uimyung Research Institute for Neuroscience, Department of Pharmacy, Sahmyook University)
de la Pena, Jun Bryan (Uimyung Research Institute for Neuroscience, Department of Pharmacy, Sahmyook University)
Paek, Se Hee (Food R&D Center, CJ CHEILJEDANG)
Seo, Yong Ki (Food R&D Center, CJ CHEILJEDANG)
Park, Seok Jun (Food R&D Center, CJ CHEILJEDANG)
Moon, Byoung Seok (Food R&D Center, CJ CHEILJEDANG)
Cheong, Jae Hoon (Uimyung Research Institute for Neuroscience, Department of Pharmacy, Sahmyook University)
Publication Information
YAKHAK HOEJI / v.58, no.6, 2014 , pp. 364-370 More about this Journal
Abstract
The aim of this study was to find optimal ratio of herbal extracts to ameliorate ethanol-induced psychomotor alterations. Four mixtures of Laurus nobilis (L. nobilis), Rosa roxburghii (R.R.) and Opuntia ficus indica (OFI) were pretreated 30 minutes before ethanol administration in rats. Behavioral activities were evaluated. Blood ethanol and acetaldehyde levels were also measured. These effects of mixture of R.R (50 mg/kg)+OFI (100 mg/kg)+L.nobilis (100 mg/kg) were better than those of other mixtures. This mixture could be used as an effective substance to develop a functional food.
Keywords
Laurus nobilis; Rosa roxburghii; Opuntia ficus indica; ethanol; behavioral; psychomotor;
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