Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Effects of Raspberry Wine on Testosterone Level of Sprague-Dawley Rats

복분자 술이 흰쥐의 testosterone분비에 미치는 영향

  • Baek Byeong Kirl (Biosafety Research Institute, Chonbuk National University) ;
  • Lim Chae Woong (Biosafety Research Institute, Chonbuk National University) ;
  • Lee Eun Yong (Biosafety Research Institute, Chonbuk National University) ;
  • Whang In Soo (Biosafety Research Institute, Chonbuk National University) ;
  • Kwon Hyuk Nyun (Biosafety Research Institute, Chonbuk National University) ;
  • Lee Hee Kwon (Korean Raspberry Experiment Station, Gochanggun Agriculture Development & Technology Center) ;
  • Lee Sung Ill (Toyama Medical and Pharmaceutical University) ;
  • Lee Hyoung Ja (Korea Advanced Food Research Institute) ;
  • Jeon Byung Hun (College of Oriental Medicine, Wonkwang University)
  • 백병걸 (전북대학교 생체안전성연구소) ;
  • 임채웅 (전북대학교 생체안전성연구소) ;
  • 이은영 (전북대학교 생체안전성연구소) ;
  • 황인수 (전북대학교 생체안전성연구소) ;
  • 권혁년 (전북대학교 생체안전성연구소) ;
  • 이희곤 (고창군 복분자 연구소) ;
  • 이성일 ;
  • 이형자 (한국식품공업협회 부설 한국식품연구소) ;
  • 전병훈 (원광대학교 한의과대학)
  • Published : 2004.08.01
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Abstract

The study was conducted to investigate per oral (PO) effects of Raspberry wine on testosterone levels in Sprague-Dawley rats. Raspberry wine of 13% alcohol concentration, was prepared from ripen fruits of Rubus coreanus fermented with Saccharomyces cervisiae. PO administration of Raspberry wine for 15 week (group A) produced dramatic increases of serum testosterone levels. Increase in the testosterone level was observed, using gamma counter with 1251 testosterone, starting from 1 week post administration. Maximum increase in testosterone level was observed at 5 week post administration, 7.486±6.482ng/mL, which was 14.6 times higher than normal and at 15 weeks post administration it was recorded as 1.84±3.516ng/mL. However, PO administration of Saccharomyces cervisiae broth (Group B) and 13% brewed alcohol (group C) for 15 weeks resulted slight increase in testosterone levels, indicating Raspberry wine as an effective phyto-testosogenic beverage of the future.

Keywords

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