• Journal of Microbiology and Biotechnology
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• 제10권2호
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• pp.272-274
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• 2000

Temperate bacteriophage P2 has a nonessential gene called old(overcoming lysoginization defection). In the presence of old, the growth of the host (Escherichia coli) with recBC- genotype is ingibited, and another bacteriophage, lambda, cannot superinfect. The Old protein has been shown to possess an exonuclease actibity. Three mutant P2s(old 1, old 17, old 49) which did gene was coned into expression vectors to produce hexahistidine-tagged proteins. The proteins were affinity-purified and shown to lose its exonuclease activity on both double-stranded and single-stranded DNA substrates. Thus, it was concluded that the lambda exclusion was related to Old's exonuclease activity.

• 한국지역사회생활과학회지
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• 제15권2호
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• pp.55-64
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• 2004

The purpose of this study was to examine the differences in skin temperature and thermal comfort of participants in a $19^\circ{C}$ room (the recommended room temperature in the winter) depending on age, sex and clothing weight. Subjects were divided into four groups (6 young males, 5 young females, 6 old males, 6 old females) and experimental trials consisted of three conditions: wearing underwear in a $19^\circ{C}$ room (19CUW), without underwear in a $19^\circ{C}$ room (19C), and without underwear in a $24^\circ{C}$ room (24C). The results indicated the following: 1) There were no significant differences in mean skin temperature based on age or sex, and the mean skin temperatures of the four groups were in the range of 32.4∼$34.0^\circ{C}$. 2) In the 19C condition, the skin temperatures of the hands and feet of old females were higher than those of the other three groups. 3) In terms of perceived thermal comfort, young females showed a tendency to feel the most uncomfortable. Both old and young groups agreed that the 24C condition was the most comfortable. 4) Relational coefficients between thermal comfort and skin temperatures were higher in the young group than in the old group. Furthermore, the perceived thermal comfort had a stronger relationship with mean skin temperatures than with local skin temperatures. 5) The mean skin temperatures of subjects who indicated they were 'comfortable' were in the range of 31∼$36^\circ{C}$ regardless of age or sex.

• 대한화장품학회지
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• 제30권1호
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• pp.135-140
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• 2004

피부 노화를 예방할 수 있는 기능성 화장품은 지질과산화를 초래하는 활성산소종(ROS)의 생성 억제와 제거 또는 collagen과 elastin의 사슬 절단 및 교차결합의 변형을 억제하는 효능이 있어야 한다. 본 연구에서는 피부 조직 중 malonedialdehydt (MDA)와 collagen이 항노화 작용이 있는 기능성 화장품의 검색 지표로서의 사용 가능성을 알아보고자 10, 25 주령 랫드의 정상 피부와 창상을 유도한 피부를 7일간 관찰하였다. 육안적인 관찰에서는 10 주령군의 11마리 랫드 중 10마리에서, 노령 랫드군의 11마리 중 8마리에서 창상이 폐쇄되었다. 10 주령 랫드와 비교했을 때 노령 랫드에서 흉터의 길이는 긴 반면에 외피의 폐쇄, collagen 밀도, 외피의 두께, 총 hydroxyproline (hyp)과 MDA 농도가 유의적으로 낮게 나타났다( p〈0.05 ∼ p 〈 0.005). 10 주령에서 진피의 규칙적으로 배열된 collagen 섬유다발과 많은 섬유아세포의 관찰과는 반대로 25 주령 이상 랫드에서는 collagen 섬유다발 사이에 많은 낭포, 소와 및 섬유아세포 수의 감소, 느슨한 외피와 진피의 결합과 얇은 외피가 관찰됨으로서 25 주령 이상의 랫드에서 감소된 hyp 양은 감소된 collagen 밀도 및 형태학적 변화와 일치하였다. 따라서 collagen 합성과 축적의 지표인 hyp의 측정은 항 피부노화 예방 및 개선제의 모니터링 연구에서 매우 유용하며 또한 피부 노화의 검객 지표로 사용이 가능하다고 사료된다.

• Journal of Gastric Cancer
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• 제2권4호
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• pp.200-204
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• 2002

Purpose: The aim of this study was to compare the clinicopathological characteristics and postoperative prognosis of two age groups with gastric cancer in order to establish the proper treatment strategy in these groups of patients. Materials and Methods: Among patients with gastric cancer who underwent a gastrectomy between 1990 and 1996 at the Department of Surgery, Kyungpook National University, the clinicopathological characteristics, including the postoperative survival, of patients younger than 40-years old were compared with those of patients over 69-years old. Results: During that period 1,125 gastric cancer patients underwent a gastrectomy. Among them, 111 patients ($9.9\%$) were less than 40-years old, and 96 patients ($8.5\%$) were over 69-years old. In the young group, 79 patients ($71.2\%$) had a poorly differentiated adenocarcinoma, and 59 patients from the elderly group ($61.5\%$) had a well- or moderately differentiated adenocarcinoma (P<0.05). Curative surgery was performed for 88 ($79.3\%$) patients in the young group and 78 ($81.3\%$) patients in the elderly group. This difference was not statistically significant. There was no statistically significant difference in the 5-year survival rates between the young and the elderly ($66.3\%\;vs.\;47.2\%$) groups, but the 5-year survival rate of the young group was significantly higher than that of the elderly group after a curative resection ($83.2\%\;vs.\;53.3\%$; P<0.05). Also the 5-year survival rate of the elderly group was significantly higher than that of the young group after a non-curative resection ($20.4\%\;vs.\;4.6\%$; P<0.05). Conclusions: For young patients, more efforts are needed to detect gastric cancer in its early stages so that a curative surgery can be performed. However, for the elderly, surgical treatment is recommended at any stage because of the relatively high survival rate, even after non-curative surgery.

• The Journal of Korean Physical Therapy
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• 제10권1호
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• pp.105-125
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• 1998

We are confronted by increase in old people due to the improvement in medical science, public hygiene and socioeconimic status in 20th century. But our medical security system for old people dees not meet the need for medical service of old people. Current medical insurance system restricts term and extent in allowance although the characteristics of the disease of the aged people need medical care of Bong duration and high cost. And in the medicaid system the speciality of the aged people is not recognized and the budget of the government is scanty. In addition many old people to our country are in economic distress due to low income. But the government authority does not give sufficient consideration for eld people in law, policy and budget. To improve social security system for old people it is necessary to increase the budget for the security of old people, to enhance the traditional respect for the aged, to improve medical security system by improving the accessibility to medical service and by expanding the allowance of medical insurance, and to expand the public welfare institutions. And these are roles for all the family. the society and the nation as well as the aged people themselves.

• 한국전문물리치료학회지
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• 제12권2호
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• pp.98-104
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• 2005

This study was done to research the general information, causes of stroke, risk factors, complications during admission of geriatric CVA inpatients. We retrospectively studied 208 above 65 years old geriatric CVA inpatients treated in Ajou university hospital from 1994 to 2003 by medical record. These were divided into two groups by following years. We were gathered information about sex, onset age, cause of stroke, number of stroke, complications, housing, family, insurance, smoking, alcohol. Most of incidence of the stroke was noted in the group of young old age (65~74 years old) and old age (75~84 years old). The occurrence rate of male stroke (38.5%) was less than of female stroke (61.5%) and the ratio of male to female was 1:1.6. The occurrence rate of ischemic stroke (72.6%) was higher than of hemorrhagic stroke. The occurrence rate of ischemic stroke increased more and more at the late stage. The most common risk factors for stroke was hypertension and complications during hospitalization were neurogenic bowl and bladder. These results of epidemiologic study may help above 65 years old geriatric CVA early treatment and prevention, rehabilitation and use basic data for multiple prospective study using stroke registry.

• 대한가정학회지
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• 제42권7호
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• pp.145-164
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• 2004

The purpose of this study is to understand how late middle-aged women in our society view and adapt to “aging”. This is a crucial step forward linking two stages, the growing young age and the declining old age, which eventually improves the qualify of life in old a9e. This qualitative study used Personal narratives extracted from tape-recorded interviews of 20 late middle-aged women in their fifties and analyzed key experiences of late middle-aged women in their transition to old age. Participants were observed to perceive not only many limitations but also alternative potentialities. First, the major challenges due to the closing young era were ‘physical declines’, including health problems and wrinkles, and ‘leaving children’. Second, the potentialities to start a new era also could be found. Many participants found themselves to be generous enough to assist others in need. In addition, they looked to adapt to new challenges. It was likely that the many adversities that they had faced made them resilient. These results show that late middle-aged women were actively negotiating with themselves and their surroundings in order to overcome their losses, maintain their potentialities, and, in the process, acknowledge their impending old age for better preparation.

• 가족자원경영과 정책
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• 제24권2호
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• pp.89-108
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• 2020

The purpose of this study was to analyze the factors influencing life satisfaction in widowhood among older females. Using the sixth Korean Retirement and Income Study (KReIS) supplementary survey data, a total sample of 1,471 women aged 65 or older whose spouse had died were selected, divided into 508 young-old (65-74), 745 middle-old (75-84), and 218 oldest-old (85+). Then, factors influencing the life satisfaction of these three groups were analyzed, based on a combination of perceived health and interpersonal satisfaction levels. It was found that among the young-old group, a higher level of subjective health perception indicated by monthly income and material support and interpersonal satisfaction linked to more frequent participation in community gathering combined for an overall higher level of life satisfaction. For the middle-old group, higher life satisfaction was provided by monthly income, informational support, and material support for subjective health perception and no diseases for interpersonal satisfaction. The oldest-old group with higher life satisfaction referred to monthly income for subjective health perception and no experience in donation activities for interpersonal satisfaction. Based on these findings, this study provides implications for policy and practice to improve the life satisfaction of elderly women who have experienced their spouse's death.

• Osong Public Health and Research Perspectives
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• 제8권5호
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• pp.308-317
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• 2017

Objectives: We aimed to examine the effects of various leisure activities on cognitive impairment in young-old (aged 65-74 years) and old-old (aged ${\geq}75$ years) adults. Methods: In total, 10,279 elderly Korean individuals from the 2014 Korean National Survey on Older Adults' cohort were enrolled in our study. Cognitive impairment was assessed using the standardized score of the Mini-Mental State Examination for Dementia Screening, whereas leisure activities were recorded via self-reporting of the extent and type of leisure activity the subjects involved in over the past year. Multivariate logistic regression was used to assess the effect of leisure activities on cognitive impairment, while controlling for potential covariates. Results: The subjects were more likely to participate in cognitive activities than in non-exercise physical activities. After controlling for selected covariates, involvement in cognitive activities was found to be a significant predictor of cognitive impairment in both the groups, whereas involvement in non-exercise physical activities was not a predictor of cognitive impairment in individuals aged ${\geq}75$ years. Moreover, depressive symptoms, rural residence, and hearing difficulties were common predictors of cognitive impairment among elderly-Korean-individuals. Conclusion: Leisure activity involvement may help delay cognitive impairment, which is often concomitant with aging. Hence, an early intervention service may significantly benefit both young-old and old-old individuals.

• 한국멀티미디어학회논문지
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• 제25권10호
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• pp.1448-1456
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• 2022

This paper studies a model to diagnose efficiency reduction of inverter using Multilayer Perceptron(MLP). In this study, two inverter data which started operation at different day was used. A Multilayer Perceptron model was made to predict photovoltaic power data of the latest inverter. As a result of the model's performance test, the Mean Absolute Percentage Error(MAPE) was 4.1034. The verified model was applied to one-year-old and two-year-old data after old inverter starting operation. The predictive power of one-year-old inverter was larger than the observed power by 724.9243 on average. And two-year-old inverter's predictive value was larger than the observed power by 836.4616 on average. The prediction error of two-year-old inverter rose 111.5572 on a year. This error is 0.4% of the total capacity. It was proved that the error is meaningful difference by t-test. The error is predicted value minus actual value. Which means that PV system actually generated less than prediction. Therefore, increasing error is decreasing conversion efficiency of inverter. Finally, conversion efficiency of the inverter decreased by 0.4% over a year using this model.