• Journal of Elementary Mathematics Education in Korea
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• v.17 no.3
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• pp.395-411
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• 2013

There are two concepts of division: measurement division and partitive or fair-sharing division. Students are expected to understand comprehensively division algorithm in both contexts. Contents of textbooks and teachers' guidebooks should be suitable for helping students develop comprehensive understanding of algorithm for whole-number division in both contexts. The results of the analysis of textbooks and teachers' guidebooks shows that they fail to connect two division contexts with division algorithm comprehensively. Their expedient and improper use of two division contexts would keep students from developing comprehensive understanding of algorithm for whole-number division. Based on the results of analysis, some ways of improving textbooks and teachers' guidebooks are suggested.

• Toxicological Research
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• v.26 no.3
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• pp.203-208
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• 2010

Bronchoalveolar lavage (BAL) is a useful tool in researches and in clinical medicine of lung diseases because the BAL fluid contains biochemical and cytological indicators of the cellular response to infection, drugs, or toxicants. However, the variability among laboratories regarding the technique and the processing of the BAL material limits clinical research. The aim of this study was to determine the suction frequency and lavage fraction number necessary to reduce the variability in lavage using male Sprague-Dawley rats. We compared the total cell number and protein level of each lavage fraction and concluded that more cells and protein can be obtained by repetitive lavage with a suction frequency of 2 or 3 than by lavage with a single suction. On the basis of total cell recovery, approximately 70% of cells were obtained from fractions 1~3. The first lavage fraction should be used for evaluation of protein concentration because fractions 2~5 of lavage fluid were diluted in manifolds. These observations were confirmed in bleomycin-induced inflamed lungs of rats. We further compared the BAL data from the whole lobes with data from the right lobes and concluded that BAL data of the right lobes represented data of the whole lobes. However, this conclusion can only be applied to general lung diseases. At the end, this study provides an insight into the technical or analytical problems of lavage study in vivo.

• School Mathematics
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• v.14 no.2
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• pp.191-212
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• 2012

In the field of arithmetic in mathematics education, there has been lack of fine-grained investigations addressing the relationship between students' construction of division knowledge with fractional quantities and their whole number division knowledge. This study, through the analysis of part of collected data from a year-long teaching experiment, presents a possible constructive itinerary as to how a student could modify her unit-segmenting scheme to deal with various fraction measurement division situations: 1) unit-segmenting scheme with a remainder, 2) fractional unit-segmenting scheme. Thus, this study provides a clue for curing a fragmentary approach to teaching whole number division and fraction division and preventing students' fragmentary understanding of the same arithmetical operation in different number systems.

• The Mathematical Education
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• v.47 no.1
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• pp.91-106
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• 2008

Interviews with 24 pupils in grade 1-2 were used to investigate awareness of the relation between situation and computation in simple quotitive and partitive division problems as informally experienced. Then it was suggested how to connect children's informal knowledge and formal knowledge of division. Most subjects counted cubes or made drawing, and related these methods to the situation described in the problems. In result, quotitive division was experienced as a dealing situation, where the number of items represented by the divisor was repeatedly taken from the whole number. And estimate-adjust was the most frequently displayed way of experiencing partitive division. Therefore, partitive division with its two measurement variables can be related to a measurement model. And children should be taught column algorithms for division with estimated-adjust which pupils used for partitive division problems.

• Journal of Society of Preventive Korean Medicine
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• v.21 no.3
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• pp.75-85
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• 2017

Objectives : The new health technology assessment (nHTA) involves evaluating the safety and efficacy of the new health technology under the Medical Services Act by the New Health Technology Assessment Project Division from 2007. The purpose of this study is to understand the status of applications and recent trends of the results, and suggest strategies for the development of new health technologies in Korean Medicine. Methods : We investigated and analyzed the results of evaluation of new health technology of whole conventional medical and the list of new health technologies in Korean Medicine provided by the New Health Technology Assessment Project Division from 2007 to 2016. Results : The number of applications for new health technology of Korean medicine was low as 41 items in the whole number of 2,013 items. The evaluation method of new health technologies in both, the whole medical and Korean medicine fields was the same, but the tendency in results was very different. Most of the new health technology items in Korean medicine were classified as existing technology (20 items), early stage technology (7 items), and Only 2 items were evaluated as research stage technology. Conclusions : In order to develop new health technology in the Korean medical field, we have made suggestions about the health technology assessment systems, R&D infrastructures, and corporation with conventional medicines.

• Reproductive and Developmental Biology
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• v.36 no.4
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• pp.255-260
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• 2012

The purpose of this study was to assess follicular viability and competence through in vitro culture of preantral follicles isolated from vitrified mouse whole ovaries. Mouse preantral follicles were enzymatically isolated from vitrified- warmed and fresh ovaries and cultured for 10 days followed by in vitro oocyte maturation. In vitro matured oocytes were fertilized and cultured to the blastocyst stage. Five minutes pre-exposure to vitrification solution of whole ovaries had significantly higher (p<0.05) oocyte survival and maturation rates than between 10 min exposure groups. Oocyte diameter was significantly smaller (p<0.05) in the 5 and 10 min exposure groups ($69.4{\pm}2.8$ and $67.8{\pm}3.1$) when compared to that of control group ($71.7{\pm}2.1$). There was no statistical significant difference in blastocyst development rates between vitrification group (8.6%) and the fresh control group (12.0%). The mean number of cells per blastocyst was significantly lower (p<0.05) in the vitrification group ($41.9{\pm}20.2$) than in the fresh control group ($55.1{\pm}22.5$). The results show that mouse oocytes within preantral follicles isolated from the vitrified whole ovaries can achieve full maturation, normal fertilization and embryo development.

• Journal of Veterinary Science
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• v.22 no.2
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• pp.24.1-24.16
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• 2021

Background: Bovine tuberculosis (TB) is caused by Mycobacterium bovis, a well-known cause of zoonotic tuberculosis in cattle and deer, and has been investigated in many physiological and molecular studies. However, detailed genome-level studies of M. bovis have not been performed in Korea. Objectives: To survey whole genome-wide single-nucleotide polymorphism (SNP) variants in Korean M. bovis field isolates and to define M. bovis groups in Korea by comparing SNP typing with spoligotyping and variable number tandem repeat typing. Methods: A total of 46 M. bovis field isolates, isolated from laryngopharyngeal lymph nodes and lungs of Korean cattle, wild boar, and Korean water deer, were used to identify SNPs by performing whole-genome sequencing. SNP sites were confirmed via polymerase chain reaction using 87 primer pairs. Results: We identified 34 SNP sites with different frequencies across M. bovis isolates, and performed SNP typing and epidemiological analysis, which divided the 46 field isolates into 16 subtypes. Conclusions: Through SNP analysis, detailed differences in samples with identical spoligotypes could be detected. SNP analysis is, therefore, a useful epidemiological tracing tool that could enable better management of bovine TB, thus preventing further outbreaks and reducing the impact of this disease.

• Tuberculosis and Respiratory Diseases
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• v.81 no.3
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• pp.216-221
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• 2018

Background: The number of immigrants with tuberculosis (TB) increases each year in South Korea. Determining the transmission dynamics based on whole genome sequencing (WGS) to cluster the strains has been challenging. Methods: WGS, annotation refinement, and orthology assignment for the GenBank accession number acquisition were performed on two clinical isolates from Chinese immigrants. In addition, the genomes of the two isolates were compared with the genomes of Mycobacterium tuberculosis isolates, from two native Korean and five native Chinese individuals using a phylogenetic topology tree based on the Multiple Alignment of Conserved Genomic Sequence with Rearrangements (Mauve) package. Results: The newly assigned accession numbers for two clinical isolates were CP020381.2 (a Korean-Chinese from Yanbian Province) and CP022014.1 (a Chinese from Shandong Province), respectively. Mauve alignment classified all nine TB isolates into a discriminative collinear set with matched regions. The phylogenetic analysis revealed a rooted phylogenetic tree grouping the nine strains into two lineages: strains from Chinese individuals and strains from Korean individuals. Conclusion: Phylogenetic trees based on the Mauve alignments were supposed to be useful in revealing the dynamics of TB transmission from immigrants in South Korea, which can provide valuable information for scaling up the TB screening policy for immigrants.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.46 no.4
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• pp.324-334
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• 2010

This investigation was carried out to research on the actual states for bycatch and discards of catches caught by funnel net from December, 2007 to June, 2010. Fishing grounds were Manheung-dong and Ocheon-dong in the coastal waters of Yeosu. The number of the investigation was 21 in Manheung-dong and 7 in Ocheon-dong fishing ground. In Manheung-dong, the species of catches were 26 of fish, 6 of cephalopod and 5 of crustacean. In Ocheon-dong, the species of catches were 25 of fish, 6 of cephalopod and 4 of crustacean. In the two all fishing grounds, the largest amount of species was revealed as gray mullet. Among these catches, the number of non marketable species that were classified and discarded ones, were 9 in Manheung-dong and 7 in Ocheon-dong. Also, among the marketable species which were small entity or too tiny catches to commercialize and not fresh ones were discarded. The proportion that they dominate in the whole catches was 37.1% in the number of catches and 5.4% in the weight of catches in Manheung-dong, and 6.9% in the number of catches and 0.3% in the weight of catches in Ocheon-dong. In case of Manheung-dong, the monthly discarding proportion was the highest with 59.4% in the number of catches in may and 17.6% in the weight of catches in November, and in case of Ocheon-dong, the both of them were the highest in February, with 28.0% in the number of catches and 5.1% in the weight of catches.

• East Asian mathematical journal
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• v.34 no.2
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• pp.203-217
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• 2018

This study examined preservice elementary teachers' patterns and tendencies in thinking of drawn models of multiplication with fractions. In particular, it investigated preservice elementary teachers' work in a context where they were asked to select among drawn models for symbolic expressions illustrating multiplication with non-whole number fractions including a mixed number. Preservice teachers' interpretations of fraction multiplication used in interpreting different types of drawn models were analysed-both quantitatively and qualitatively. Findings and implications are discussed and further research is suggested.