• The Korea Journal of Herbology
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• v.33 no.5
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• pp.81-88
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• 2018

Objectives : The aim of this study was to investigate the protective effects of an aqueous extract from Taxillus chinensis (DC.) Danser (TCE) in Monosodium iodoacetate (MIA)-induced osteoarthritis (OA) rat model. Methods : Sprague Dawley male rats were divided into the following four groups (n=6 per group): Normal (saline control), MIA (MIA-induced OA with vehicle), TCE (MIA-induced with TCE treatment), and IM (MIA-induced with indomethacin treatment). Rats in which OA was induced by MIA were treated with TCE (200 mg/kg) or indomethacin (1 mg/kg) for 4 weeks. Weight-bearing on the hind legs and body weights were measured weekly. At the end of the experiment (3 weeks after MIA injection), serum aspartate aminotransferase and alanine aminotransferase levels were measured to assess the liver toxicity induced by TCE. Its effects on serum inflammatory cytokine levels and tissue histopathology were also evaluated. Results : TCE restored the hind limb weight-bearing distribution. Serum levels of Interleukin 6 (IL-6), Tumor necrosis factor alpha (TNF-${\alpha}$) and Leukotriene B4 (LTB4) were significantly higher in the MIA group than in the Normal group, but serum IL-6 levels were significantly lower in the TCE group. In the TCE group, the synovial membrane was protected in hematoxylin and eosin and Safranin-O staining, respectively. Conclusions : TCE recovered the hind paw weight bearing distribution, inhibited the production of inflammatory cytokine, and protected synovial tissue and cartilage in the OA rat model. Therefore, TCE appears to be an effective therapeutic agent for treating OA and OA-related symptoms.

• Korean Journal of Veterinary Service
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• v.46 no.2
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• pp.175-179
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• 2023

This study was conducted to find out the compensation strategy through kinetic gait analysis by comparing dog with congenital luxation of the shoulder joint and normal dog. Ground reaction forces were recorded for all limbs while normal poodle dog and poodle dog with shoulder joint luxation was allowed to walk on an instrumented platform. The dogs were evaluated for maximal vertical force (MVF), body load distribution (BLD), and symmetry index (SI). The MVF was increased in the contralateral forelimb of luxated shoulder joint. The SI was also increased in a dog with dislocated shoulder joints in the forelimbs. For BLD, the maximum load distribution increased centrally, but the total load distribution decreased in the ipsilateral forelimb paw. In contrast, total load distribution was increased in the contralateral forelimb paw. During forelimb lameness, changes in weight-bearing load showed compensatory load redistribution. These biomechanical changes may lead to changes in the musculoskeletal system in a dog with luxated shoulder.

• The Journal of Engineering Geology
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• v.19 no.4
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• pp.493-499
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• 2009

Recently, the construction of Concrete Faced Rockfill Dam (CFRD) is increasing because rock material resources are plenty in Korea. Bedding zone in the CFRD is necessary enough bearing capacity to support the concrete face slab uniformly and enough impermeability to prevent the loss of fine soils in case of leakage from the concrete slab face. Therefore, cut-off the water leakage in bedding zone securely is the key factor influencing the safety of CFRD. Tested materials satisfied with the specification of particle size distribution at the Bedding Zone area are chosen for conducting permeability tests, which are done to evaluate the property of cut off the materials. Based on the test results, the effects of cut off the materials are investigated by considering the coefficient of permeability, the soil particle distribution, and the dry unit weight. Especially, the relationships between coefficient of permeability with effective size(D10), dry unit weight, and weight passing percent the No.4 sieve are suggested, and also the variation of coefficient of permeability with time are proposed.

• Special Issue of the Society of Naval Architects of Korea
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• 2005.06a
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• pp.138-143
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• 2005

Recently, it is much more required to approach the accurate shaft alignment analysis according to the tendency of active showing in large container vessel and that of the heavy weight of propeller in connection with it. Shaft alignment calculation lies upon how the pressure apply on bearings properly in operation of main engine and how the stress of shaft puts within that of limit of bearing material and how the movement of shaft is prospected owing to propeller forces and moments. Therefore, we have conducted the shaft alignment calculation of very large container vessel considering the deformation of hull structure and the propeller forces and moments and the static and dynamic condition of shaft. The calculation results show the pressure distribution of aft bush and the movement of shaft in bearing. The shaft alignment calculation helps the stable application of shaft alignment, which was proved in sea trial.

• Journal of The Korean Society of Integrative Medicine
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• v.1 no.2
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• pp.37-46
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• 2013

Purpose : The purpose of the research was to analyze foot pressure, foot temperature, and correlation between foot pressure and foot temperature to grasp impact on foot pressure and body temperature distribution chart depending on functional difference of leg length. Method : After measuring leg length, put 15 students whose functional difference of leg length was over 10mm to difference group and 15 students whose functional difference of leg length was under 5mm to normal group and categorize soles of foot into 6 sections of hallux head, 1st metatarsal head, 2-4 metatarsal head, 5 metatarsal head, lateral heel, and then measure by foot pressure analyzer to analyze characteristic of pressure distribution and classify into front of the lower leg, back of the lower leg, soles of foot and measure by body temperature analyzer to analyze by checking body temperature. Result : Weight difference depending on foot pressure and body temperature was bigger when functional difference of leg length was bigger, and it could be confirmed that foot pressure and body temperature of short leg side were higher than those of short leg side. Thus, if difference exists in leg length, weight load on short leg side increases which results in higher foot pressure and body temperature, therefore enabling an assumption that mechanical problem will occur in short leg. Conclusion : When functional leg length inequality, weight bearing and pressure was getting high as a result, temperature was getting high in short leg.

• Journal of Yeungnam Medical Science
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• v.11 no.2
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• pp.284-292
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• 1994

In transtrochanteric rotational osteotomy to treat osteonecrosis of the femoral head, the necrotic superior anterior femoral head is rotated anteriorly around the longitudinal neck axis so that the weight bearing force is transferred to the intact posterior surface. The ratio of transposed intact articular surface of the femoral head to the weight-bearing surface of the acetabulum on postoperative anteroposterior view of the hip roentgenograph is the most important indicator of the prognosis. During the period from December 1992 to June 1994, we treated 31 hips in 28 patients who were indicated for the anterior rotational osteotomy among the patients of osteoncrosis of the femoral head. Among the patients, male were 27 and female was one. Age distribution was from 13 to 62 years old and mean age was 44.3. According to the Ficat and Arlet classification, II A was most in number as 16 II B was 7 and III was 8. As their etiolgic factors, alcohol was most in number as 18, steroid was 3, idiopathic was 5 and trauma was 2. The mean rate of the intact area of the posterior part of the femoral head to the total articular surface on the preoperative lateral view of the hip roentgenograph was 41.8%, The mean ratio of transposed intact articular surface of the femoral head to the weight bearing surface of the acetabulum was 53.8%, Fixation devices were screws or dynamic hip screw.

• Tribology and Lubricants
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• v.39 no.4
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• pp.139-147
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• 2023

Cavitation phenomena observed during the operation of a submerged plain journal bearing (PJB) can affect bearing performance parameters such as dynamic coefficients, whirl frequency ratio, and critical mass. This study presents numerical solutions of the Reynolds equation for steadily and dynamically loaded submerged PJBs with half-Sommerfeld (HS), Reynolds, and Jakobsson-Floberg-Olsson (JFO) cavitation models when the supply pressure is larger or equal to the cavitation pressure. The loads at various eccentricity ratios are identical; however, the attitude angle is approximately 6% smaller when the eccentricity ratio is between 0.2 and 0.7 and the JFO model is used, compared to that when the Reynolds model is used. Dynamic coefficients obtained with the HS and Reynolds model show good agreement with each other, except for k_xz, which is sensitive to changes in the force normal to the rotor weight, and is attributed to the difference in the attitude angle obtained with each cavitation model. Stiffness coefficients are determined using the pressure distribution in the film, and therefore, when the JFO model is used, the direct stiffness coefficients are affected and show opposite signs for most eccentricity ratios. The mass-conservative JFO model can predict at least a 30% smaller critical mass compared to that using the HS and Reynolds models. Thus, the instability analysis results can change based on the cavitation model used in a submerged PJB. The results of this research indicate that the JFO model should be used when designing a rotor system supported by submerged PJBs.

• Journal of Preventive Medicine and Public Health
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• v.38 no.3
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• pp.291-297
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• 2005

Objectives : The effects of exercise on bone density have been found to be inconsistent in previous studies. We conducted a cross-sectional study in premenarcheal girls to test two hypotheses to explain these inconsistencies. Firstly,'the intensity of mechanical strain, in terms of the ground reaction force(GRF), has more important effects on the bone mass at a weight-bearing site', and secondly, 'calcium intake modifies the bone response to exercise'. Methods : The areal bone mineral density was measured at the Os calcis, using peripheral dual energy X-ray absorptiometry, in 91 premenarcheal girls aged between 9 and 12 years. The intensity of mechanical strain of exercise was assessed by a self-report questionnaire and scored by the GRF as multiples of body weight, irrespective of the frequency and duration of exercise. The energy and calcium intake were calculated from the 24-hour dietary recall. An analysis of covariance(ANCOVA) was used to determine the interaction and main effects of exercise and calcium on the bone density, after adjusting for age, weight, height and energy intake. Results : The difference in the bone density between moderate and low impact exercise was more pronounced in the high than low calcium intake group. The bone density for moderate impact exercise and high calcium intake was significantly higher than that for low impact exercise (p=0.046) and low calcium intake, after adjusting for age, weight, height and energy intake. Conclusions : Our study suggests that the bone density at a weight-bearing site is positively related to the intensity of mechanical loading exercise, and the calcium intake may modify the bone response to exercise at the loaded site in premenarcheal girls.

• Journal of the Korean Geotechnical Society
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• v.24 no.1
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• pp.119-130
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• 2008

Uncertainties in physical and engineering parameters for the design of shallow foundations arise from various aspects such as inherent variability and measurement error. This paper aims at investigating and reducing uncertainty from deterministic method by using the reliability-based design of shallow foundations accounting for the variation of various design parameters. A probability distribution type and statistics of random variables such as unit weight, cohesion, infernal friction angle and Young's modulus in geotechnical engineering are suggested to calculate the ultimate bearing capacities and immediate settlements of foundations. Reliability index and probability of failure are estimated based on the distribution types of random variables. Widths of foundation are calculated at target reliability index and probability of failure. It is found that application and analysis of the best-fit distribution type for each random variables are more effective than adoption of the normal distribution type in optimizing the reliability-based design of shallow foundations.

• Journal of Korean Physical Therapy Science
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• v.11 no.4
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• pp.29-37
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• 2004

Measurements of plantar pressure provide an indication of foot and ankle function during gait and other functional activities because the foot and ankle provide necessary support and flexibility for weight bearing and weight shifting while people are performing these activities. Plantar pressure is being increasingly used in both research and clinical practice to measure the effects of various footwear and physical therapy intervention. The influence of walking speed and ground inclination on plantar pressure parameters However has not been evaluated in detail. So, in this study to determine the effect of changes in walking speed and ground inclination on plantar pressure treadmills with different walking speeds and inclination were used. Plantar pressure parameters were measured with the Parotec system using the walking and running in 20 healthy participants(10 male, 10 female) aged $20{\sim}28$(mean 22.22, S.D.2.26 years) when slow walking and running. The result of this study with increased die walking speed, the peak pressure of 1st, 5th metatarsal head and total contact time and impulse total at the forefoot was affected by walking speed; however, die peak pressure, contact time and impulse total at the forefoot was not affected by ground inclination.