• Journal of the Korean Society of Physical Medicine
• /
• v.9 no.1
• /
• pp.45-53
• /
• 2014

PURPOSE: In this study, we tried to find out what kind of exercise was more effective in sleep disorder by comparing melatonin in blood after applying low intensity with high intensity exercise to sleep disordered rats induced by experiment. METHODS: We used male Sprague-Dawley rats which were 8weeks old and weighted 300g. They were supplied with water and food without any restriction. We kept the room temperature at $25^{\circ}C$ and controld the length of day and night in 12 hours blocks, respectively. We divided the rats 60 into 2 groups. To one group we applied low intensity exercise, and to the other we applied high intensity exercise for 15minutes per day over a period of 4 weeks. We extracted the blood from abdominal aorta before, after exercise, moved into EDTA tube, performed centrifugation. We decanted the serum $200{\mu}l$ from the blood into microcentrifuge tube by samples and moved into polypropylene culture tubes with micro pipette. We split enzyme solution $50{\mu}l$ into the tubes with melatonin direct kits and make them react at $37^{\circ}C$ for 2 hours. We split assay buffer $50{\mu}l$ into each tube and mixed melatonin tracer $50{\mu}l$ and melatonin antiserum $50{\mu}l$, respectively. After we made them react in room temperature, we decanted the superficial layer with a centrifuge and measured the activity for 1 minute by competitive method with ${\gamma}$-counter equipment. We draw a standard curve through logit-log graph with CPM(counts per minute) and counted the melatonin by B/B0. We conducted independent t-test to examine the homogeneous of melatonin value of before low-intensity and high-intensity exercise. We performed paired t-test to compare before and after low-intensity and high-intensity exercise, respectively. We carried out independent t-test to compare melatonin value after low-intensity and high-intensity exercise. Significance level was .05. RESULTS: The results were as follows; firstly melatonin was more increased in the group who was exposed to high intensity exercise when we compared before to after high and low intensity exercise, respectively. Secondly, high intensity exercise was more effective than low intensity exercise when we compared the two. CONCLUSION: In conclusion, secretion of melatonin which is the material of sleep improvement could be promoted by high intensity exercise. Low intensity exercise acted as a stress rather than improving sleep and had a negative effect on the secretion of melatonin because the melatonin was affected by stress.

• Proceedings of the IEEK Conference
• /
• 2000.11b
• /
• pp.277-280
• /
• 2000

In this paper, we designed a turbo decoder using VHDL. To maximize effective free distance of the turbo code, we implemented pseudo random interleaver. A MAP(Maximum a posteriori) decoder is used as a primimary decoder. We avoided multiplication by using lookup tables(ROM). We expect that this small-sized turbo decoder is suitable for mobile communication. We simulated turbo decoder with Altera MAX+PLUS II.

• Korean Journal of Oriental Medicine
• /
• v.8 no.2 s.9
• /
• pp.47-65
• /
• 2002

This project is planned to grasp the present situation of traditional medicine part in our country and to study protection method about this by the intellectual property which is the international concerning point recently. Through this, we will be able to devise means to deal with protection method of traditional medicine being developed by WIPO now. Traditional medicine field In our country Is organized with specific condition separated into the part of institution and the part of non-institution. So, because of the closed peculiarity, we have experienced the difficulties to understand the real facts about traditional medicine. We cannot be indifferent to the matter anymore. Because the expectation of object people is high, we could expect the realization of research content. In 1 detail project, we investigated the situation of traditional medicine in our country through various collecting methods for excavation of oriental treatment technique and herb medicine which is worth protecting. With it, we sorted again into 56 kinds of 11 parts through analysis of validity in the way of oriental medicine. And we tried to link this up 2 detail project which is about legal and institutional guarantee concerning protection. furthermore, we tried to find approach ways for security of objectivity into 4 steps with the example of model disease. we could complete practical classification of traditional medicine in our country. In 2 detail project, we studied the protection method by the intellectual property through research result in 1 detail project. For this, we observed an outline of the intellectual property including a patent application analysis in folk traditional medicine part, and problems of traditional medicine protection and world trend by traditional knowledge protection tendency and the patent law In domestic traditional medicines, the aspects unprotectable with the patent law now were remained. So, we suggested supplementary plan. And we also suggested the freedom of utilization between traditional medicine possession countries (in-situ utilization) and the demand compensation payment for a third country (ex-situ utilization) in connection with international movement.

• Journal of Environmental Impact Assessment
• /
• v.8 no.3
• /
• pp.49-59
• /
• 1999

In this study, we individualize the clauses to sort out the troubled ones, draw up a interrelation model in order to visually organize the relations, and finally, suggest the desirable application idea. The interrelation model suggested in this study has been made based on the matrix method. On this matrix, we arranged the environmental factors on horizontal and vertical axis, and when we describe the relation of each factors, we set the horizontal axis as the base and divided the content into three grades : Fine, Medium, and Poor. In addition to that, we expressed those three grades into numerical value like 3 points for Level Fine, 2 points for Level Medium, and 1 point for Level Poor and then, we converted this numerical values into index numbers. We could classify the index numbers such as AS, PS, Q-index, P-index. AS is an index numerically shows the degree of giving environmental effect, PS is an index numerically shows the degree of receiving environmental effect, Q-index is an index shows the aggravate degree, and P-index shows the relation degree. The Q/P-index with large numbers has considerable effect on the environmental system, while the small numbered Q/P-index barely effect on the environmental system. Moreover, we classified the environmental factors into 5 levels(I~V) according to the relations between the Q-index and P-index. Level I is less affected by the environment and has more giving effect, while Level V is more sensitively affected by the environment and has more receiving effect, which we considered important. Therefore, we could come up with the result that if we consider the each level of factors when we evaluate the EIA, the result would be far more accurate and reliable since it contains mutual relation aspect of EIA. The suggested interrelation model in this thesis is presentable as one of those scoping system. We highly believe the need of scoping system in EIA and suggest the interrelation model as the alternative idea for scoping system.

• The Journal of Internal Korean Medicine
• /
• v.34 no.2
• /
• pp.204-214
• /
• 2013

Objectives : This study was designed to investigate the cellular and molecular mechanisms of anti-inflammatory activity of the water extract of Polygala tenuifolia Willd. (Pt-WE). Methods : Using lipopolysaccharide (LPS)-stimulated murine RAW264.7 cells, we examined inflammatory mediators such as nitric oxide (NO), inducible NO synthase (iNOS), cyclooxygenase (COX)-2 and prostaglandin $E_2$ ($PGE_2$). Also, the inhibitory effect of Pt-WE on the activity of activator protein 1 (AP-1) and upstream signaling molecules was evaluated. To assess the protective effect of Pt-WE on hydrochloride/ethanol (HCl/EtOH)-induced gastric ulcer in mice, we compared Pt-WE (200 mg/kg) with ranitidine (50 mg/kg) treated mice's gastric mucosa, based on gross observations. Results : Pt-WE inhibited LPS-induced production of NO, $PGE_2$ in a dose-dependent manner, without causing cytotoxicity. Pt-WE suppressed AP-1 activation by reducing generations of both c-Jun and c-Fos. In addition, Pt-WE inhibited the p-MKK 4/7 (mitogen-activated protein kinase kinase 4/7) and p-JNK (c-Jun N-terminal kinase) 1 in LPS-stimulated RAW264.7 cells. HCl/EtOH-induced gastric ulcer lesions were inhibited by pre-treatment of Pt-WE based on gross observations. In addition, Pt-WE decreased the phosphorylation level of JNK. Conclusions : These results demonstrate that Pt-WE has anti-inflammatory and gastroprotective effects. Thus, Pt-WE may be used widely in treatment of not only neurodegenerative diseases but also inflammatory diseases.

• Proceedings of the Korean Vacuum Society Conference
• /
• 2014.02a
• /
• pp.247.1-247.1
• /
• 2014

The capacitive coupled plasma is used widely in the semiconductor industries. Especially, the uniformity of the industrial plasma is heavily related with defect ratio of devices. Therefore, the industries need the capacitive coupled plasma source which can generate the uniform plasma and control the plasma's uniformity. To achieving the uniformity of the large area plasma, we designed multi-powered electrodes. We controlled the uniformity by controlling the power of each electrode. After this work, we started to research another concept of the plasma device. We make the plasma chamber that has multi-ground electrodes imaginary (CST microwave studio) and simulate the electric field. The shape of the multi-ground electrodes is ring type, and it is same as the shape of the multi-power electrodes that we researched before. The diameter of the side electrode's edge is 300mm. We assumed that the plasma uniformity is related with the impedance of ground electrodes. Therefore we simulated the imaginary chamber in three cases. First, we connected L (inductor) and C (capacitor) at the center of multi-ground electrodes. Second, we changed electric conductivity of multi-ground electrode. Third, we changed the insulator's thickness between the center ground electrode and the side ground electrode. The driving frequency is 2, 13.56 and 100 MHz. We switched our multi-powered electrode system to multi-ground electrode system. After switching, we measured the plasma uniformity after installing a variable vacuum capacitor at the ground line. We investigate the effect of ground electrodes' impedance to plasma uniformity.

• Journal of the Ergonomics Society of Korea
• /
• v.30 no.2
• /
• pp.303-310
• /
• 2011

In this study, we employ CPM-GOMS analysis for explaining physical and cognitive processes and for quantitatively predicting when users are typing Korean text messages on mobile phones using both hands. First, we observe the behaviors of 10 subjects, when the subjects enter keypads with both hands. Then, basing upon MHP, we categorize the behaviors into perceptual, cognitive, motor operators, and then we analyze those operators. After that, we use the critical paths to model two task sentences. Also, we used Fitts' law method which was applied many times to predict text entering time on mobile phone to compare with the results of our CPM-GOMS model. We followed Lee's (2008) method that is well suited for text entry task using both hands and calculate total task time for each task sentences. For the sake of comparison between the actual data and the results predicted from our CPM-GOMS model, we empirically tested 10 subjects and concluded that there were no significant differences between the predicted values and the actual data. With the CPM-GOMS model, we can observe the human information processes composed on the physical and cognitive processes. Also we verified that the CPM-GOMS model can be well applied to predict the users' performance when they input text messages on mobile phones using both hands by comparing the predicted total task time with the real execution time.

• The Mathematical Education
• /
• v.49 no.1
• /
• pp.15-37
• /
• 2010

In this study, we investigated the application of oriental history of mathematics in school mathematics teaching. We set up three study problems to achieve this purpose. First, we analyze the middle and high school mathematics textbooks and auxiliary books. Second, we survey the mathematics teacher's knowledge and degree of application on history of mathematics. Third, we develop the teaching and learning materials on oriental history of mathematics. We performed three study-methods to settle above study problem. First, we analyzed 24 textbooks and auxiliary books for study problem 1. There were 6 middle school mathematics textbooks and 6 auxiliary books and also 6 high school mathematics textbooks and 6 auxiliary books. We categorized the contents into "anecdote", "systematization", "application of problem", "expansibility of thought", and "comparative of the contents". Second, we surveyed the 78 mathematics teachers's knowledge and degree of application using questionnaire about knowledge and application on history of mathematics. The questionnaire was made up of four types of question; the effect of material about history of mathematics, the understanding of western history of mathematics, the understanding of oriental history of mathematics; the direction of development of teaching material. Third, we exemplified the teaching and learning materials about three categories: "anecdote", "comparative of the contents".

• Proceedings of the KOSOMBE Conference
• /
• v.1997 no.11
• /
• pp.583-586
• /
• 1997

In this study, we proposed an application of wavelet transform or analysis of ultrasound echo signals to improve troubles of convenianced methods such as SDM, SSM. We examined method using wavelet transform to prove again our proposal which we have proposed prior time. At first, we made phantoms by adding 0.01, 0.015, 0.02, 0.025, 0.03, 0.035, 0.04, 0.045, 0.05($g/cm^3$) on constant quantity of distilled water and agar, and collected echo signals. We used SDM(spectral difference method) and WTM(wavelet transform method) as signal processing method. To compare with WTM, SDM was used. In WTM, we selected detail signals of level 3 of Daubechies 16, and got derivative, calculated area of it. Next, we calculated slopes. In SDM, it was 0.0308 and in WTM, it was 0.5248. As a result, we knew that we could know that the values using WTM showed more detailed than those using SDM. So we could concluded wavelet transform is very useful and powerful in ultrasound tissue characterization.

• International Journal of Aeronautical and Space Sciences
• /
• v.5 no.2
• /
• pp.1-8
• /
• 2004

Real-Time Kinematic GPS positioning is widely used for many applications.Resolving ambiguities is the key to precise positioning. Integer ambiguity resolution isthe process of resolving the unknown cycle ambiguities of double difference carrierphase data as integers. Two important issues of resolving are efficiency andreliability. In the conventional search techniques, we generally used chi-squarerandom variables for decision variables. Mathematically, a chi-square random variableis the sum of mutually independent, squared zero-mean unit-variance normal(Gaussian) random variables. With this base knowledge, we can separate decisionvariables to several normal random variables. We showed it with related equationsand conceptual diagrams. With this separation, we can improve the computationalefficiency of the process without losing the needed performance. If we averageseparated normal random variables sequentially, averaged values are also normalrandom variables. So we can use them as decision variables, which prevent from asudden increase of some decision variable. With the method using averaged decisionvalues, we can get the solution more quicklv and more reliably.To verify the performance of our proposed algorithm, we conducted simulations.We used some visual diagrams that are useful for intuitional approach. We analyzedthe performance of the proposed algorithm and compared it to the conventionalmethods.