• Title/Summary/Keyword: vulnerable

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Identification of Molecular Markers for Population Diagnosis of Korean Fir (Abies koreana) Vulnerable to Climate Change

  • Kim, Dong Wook;Park, Da Young;Jeong, Dae Young;Park, Hyeong Cheol
    • Proceedings of the National Institute of Ecology of the Republic of Korea
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    • v.1 no.1
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    • pp.68-73
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    • 2020
  • Korean fir (Abies koreana) is an evergreen coniferous tree species that is unique to South Korea. A. koreana is found in a limited sub-alpine habitat and is considered particularly vulnerable to climate change. Identification of populations vulnerable to climate change is an important component of conservation programs. In this study, a heat stress-induced transcriptome RNA-seq dataset was used to identify a subset of six genes for assessment as candidate marker genes for ecologically vulnerable populations. Samples of A. koreana were isolated from ecologically stable and vulnerable regions of the Halla and Jiri mountains, and the expression levels of the six candidate markers were assessed using quantitative real-time polymerase chain reaction. All six of the candidate genes exhibited higher expression levels in samples from vulnerable regions compared with stable regions. These results confirm that the six high temperature-induced genes can be used as diagnostic markers for the identification of populations of A. koreana that are experiencing stress due to the effects of climate change.

An Ethical Consideration on the Standard Operating Procedure Operation Status and the Ethical Review of the Vulnerable Research Subjects of Institutional Review Board, a Medical Institution in Korea (우리나라 의료기관 Institutional Review Board의 취약한 연구 대상자 관련 표준운영지침서 운영 현황과 윤리적 고찰)

  • Eun Hwa Byun;Byung In Choe
    • The Journal of KAIRB
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    • v.5 no.1
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    • pp.21-32
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    • 2023
  • Purspose: The purpose of this study is to examine the meaning and definition of vulnerable subjects in clinical trials in light of domestic and international regulations and guidelines, to analyze the contents of standard operation procedures (SOPs) among advanced general hospitals in Korea that conduct clinical trials, and to examine deliberation procedures for operation plans. Methods: The study examined how vulnerable research subjects were defined and described in related regulations and the classification of vulnerable research subjects presented in the IRB/HRPP SOPs of 18 clinical trial institutions, including 11 AAHRPP-accreditated general hospitals in Korea, as well as the operation of the IRB deliberation. Results: Among all domestic and international regulations and guidelines, only the The Council for International Organization of Medical Sciences (CIOMS) guidelines explain why vulnerability is related to judgments on the severity of physical, psychological, and social harm, why individuals are vulnerable, and for what reasons. However, the classification of vulnerable subjects by institutions differed from the classification by the International Conference on Harmonization-Good Clinical Practice (ICH-GCP). A total of the 16 institutions classified children and minors as vulnerable research subjects. 14 institutions classified subjects who cannot consent freely were classified as vulnerable subjects. 15 institutions classified sujects who can be affected by the organizational hierarchy were classified as vulnerable subjects. Subjects in emergency situations were regarded as vulnerable research subjects in 8 of institutions, while people in wards, patients with incurable diseases, and the economically poor including the unemployed were categorized as vulnerable research subjects in 7, 4, and 4 of institutions, respectively. Additionally, some research subjects were not classified as vulnerable by ICH-GCP but were classified as vulnerable by domestic institutions 15 of the institutions classified pregnant women and fetuses as vulnerable, 11 classified the elderly as vulnerable, and 6 classified foreigners as vulnerable. Conclution: The regulations and institutional SOPs classify subjects differently, which may affect subject protection. There is a need to improve IRBs' classifications of vulnerable research subjects. It is also necessary to establish the standards according to the differences in deliberation processes. Further, it is recommended to maintain a consistent review of validity, assessment of risk/benefit, and a review using checklists and spokeperson. The review of IRB is to be carried out in a manner that respects human dignity by taking into account the physical, psychological, and social conditions of the subjects.

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Climate Change Vulnerability Assessment in Rural Areas - Case study in Seocheon - (농촌지역 기후변화 취약성 평가에 관한 연구 - 서천군을 대상으로 -)

  • Lee, Gyeongjin;Cha, Jungwoo
    • Journal of Korean Society of Rural Planning
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    • v.20 no.4
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    • pp.145-155
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    • 2014
  • Since greenhouse gas emissions increase continuously, the authorities have needed climate change countermeasure for adapting the acceleration of climate change damages. According to "Framework Act on Low Carbon, Green Growth", Korean local governments should have established the implementation plan of climate change adaptation. These guidelines which is the implementation plan of climate change adaptation should be established countermeasure in 7 fields such as Health, Digester/Catastrophe, Agriculture, Forest, Ecosystem, Water Management and Marine/Fisheries. Basically the Korean local governments expose vulnerable financial condition, therefore the authorities might be assessed the vulnerability by local regions and fields, in order to establish an efficient implementation plan of climate change adaptation. Based on this concepts, this research used 3 methods which are LCCGIS, questionnaire survey analysis and analysis of existing data for the multiphasic vulnerable assessment. This study was verified the correlation among 7 elements of climate change vulnerability by 3 analysis methods, in order to respond climate change vulnerability in rural areas, Seocheon-gun. If the regions were evaluated as a vulnerable area by two or more evaluation methods in the results of 3 methods' comparison and evaluation, those areas were selected by vulnerable area. As a result, the vulnerable area of heavy rain and flood was Janghang-eup and Maseo-myeon, the vulnerable area of typhoon was Janghang-eup, Masan-myeon and Seo-myeon. 3 regions (i.e. Janghang-eup, Biin-myeon, Seo-myeon) were vulnerable to coastal flooding, moreover Masan-myeon, Pangyo-myeon and Biin-myeon exposed to vulnerability of landslide. In addition, Pangyo-myeon, Biin-myeon and Masan-myeon was evaluated vulnerable to forest fire, as well as the 3 sites; Masan-myeon, Masan-myeon and Pangyo-myeon was identified vulnerable to ecosystem. Lastly, 3 regions (i.e. Janghang-eup, Masan-myeon and Masan-myeon) showed vulnerable to flood control, additionally Janghang-eup and Seo-myeon was vulnerable to water supply. However, all region was evaluated vulnerable to water quality separately. In a nutshell this paper aims at deriving regions which expose climate change vulnerabilities by multiphasic vulnerable assessment of climate change, and comparing-evaluating the assessments.

An Analysis of the Vulnerable-Pedestrian Crossing Time in Test Crosswalk (설험용 횡단보도에서 교통약자 가로횡단시간 분석)

  • Kim, Tae-Ho;Hu, Uk;Hwang, Eu-Pyo;Won, Jai-Mu
    • Journal of the Korean Society of Safety
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    • v.23 no.4
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    • pp.90-98
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    • 2008
  • Presently, pedestrian's signal time models in korea are not considering Vulnerable-Pedestrian. So, the safety of Vulnerable-Pedestrian is being threatener and the number of accidents is increasing. Besides, the existing operational system for pedestrians can't offer the cross signal time in road corresponded the changing environment when the school zone is revitalized and the Silver zone is introduced for Vulnerable-Pedestrian. Conclusively, Vulnerable-Pedestrian's signal time models which are able to consider classified Vulnerable-Pedestrian speed, Vulnerable-Pedestrian perception-reaction time, Vulnerable-Pedestrian Spare(congestion-delay) time are suggested by the result of experiment in virtual crosswalk. the application of suggested models in this study to the site. It is possible to use as a basic stuff on study of pedestrian's signal time and expected to contribute the safety and mobility in future.

A Research on the Health Care and the Demand for Visiting Health Care Services for Vulnerable Children in Comparison with Non-vulnerable Children in a Region (취약계층과 일반군 영유아의 건강관리 현황 및 방문건강관리사업 요구도 비교조사)

  • Nam, Hye Kyung
    • Journal of Korean Public Health Nursing
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    • v.30 no.3
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    • pp.556-569
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    • 2016
  • Purpose: This study aimed to provide baseline data on the health care of children and the demand for visiting health care services in one region in efforts to support the implementation of visiting health care services for vulnerable children. Methods: Seventy-three children and their caregivers from the vulnerable social group and 82 children and their caregivers from the general group were selected as research participants. The data were collected through home visiting survey by professional nurses. Results: Children from the vulnerable social group were at higher risk of poor health care than the general group. Regarding home safety, vulnerable children were more likely to be exposed to unsafe conditions. With respect to nutrition, developmental play, developmental screening test, and home safety, visiting health care services were in demand for caretakers. Conclusion: These results indicate that to promote health care and safety conditions for vulnerable children, it is necessary to implement visiting health care programs that include the management of vaccination, medical check-up, growth and development, home safety, and nutrition. These findings can be used as the baseline data for the development of visiting health care programs for vulnerable children.

Survey on Health Care and Household Safety Management for Vulnerable Children (취약계층 영유아의 건강과 안전관리 실태조사)

  • Nam, Hye Kyung
    • Journal of muscle and joint health
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    • v.21 no.3
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    • pp.246-254
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    • 2014
  • Purpose: This study aims to provide baseline data on children's health care and household safety management in one region and to support implementation of customized visiting health care services for children. Methods: 51 children and their caregivers from socially vulnerable group and 69 children and their caregivers from general group are selected as research participants. Data were collected through home visiting survey by 10 professional nurses. Results: Children from socially vulnerable group are at higher risks of poor health care and safety accidents in households than general group. Rates of taking developmental screening tests, medical check-up remain considerably low in vulnerable social group. Regarding home safety, vulnerable children are more likely to be exposed to unsafe conditions. Conclusion: These results indicate that in order to promote health care and safety conditions for vulnerable children, it is necessary to implement customized visiting health care programs which actually can reach vulnerable households and meet their demands. These findings can be used as baseline data to develop customized visiting health care programs for children.

Influencing Factors of the Metabolic Index and Cardiovascular Risk Factors on Depressive and Non-depressive Groups in the Vulnerable Diabetic Elderly Women (취약계층 당뇨병 여성노인의 대사증후군지표와 심혈관 위험정도가 우울증상 여부에 미치는 요인)

  • Sung, Kiwol
    • Journal of Korean Biological Nursing Science
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    • v.21 no.2
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    • pp.123-132
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    • 2019
  • Purpose: The purpose of this study was to identify influencing factors of metabolic index and cardiovascular risk factors, on depressive and non-depressive groups, in vulnerable diabetic elderly women. Methods: Participants were 137 vulnerable diabetic elderly women, using health centers in D city. Data were collected through interviews September though December 2017. The metabolic index was measured using National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III), and cardiovascular risk factors were measured using Framingham Risk Score (FRS). Depressive and non-depressive groups were divided by the score of Geriartric Depress Scale Short Korea Version (GDSSF). Collected data were analyzed using a x2 test, independent t-test, and binary logistic regression, with the SPSS/WIN 25.0 program. Results: Vulnerable diabetic elderly women, did not exercise in the depressive groups, and had higher triglyceride (TG), total cholesterol (TC) and larger waists, than in the non-depressive group. Results show that lack of exercise (OR= 6.30), is the highest risk factor, influencing the depressive symptom in vulnerable diabetic elderly women. Conclusion: These results suggest that to reduce depressive symptom levels among vulnerable diabetic elderly women, nursing interventions are needed to increase exercise and decrease TG, TC, and waist size, particularly in improving exercise of vulnerable diabetic elderly women.

Barriers and Solutions of Immunization Programs for Children among Vulnerable Classes in Community Health Centers (취약계층 아동을 위한 보건소 예방접종사업의 장애요인과 해결방안)

  • Han, Young-Ran;Park, Hye-Sook
    • Journal of Korean Public Health Nursing
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    • v.23 no.1
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    • pp.113-128
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    • 2009
  • Purpose: To explore the barriers and solutions of immunization programs for children among vulnerable classes in the position of service providers in Community health centers. Method: Data were collected through focus group interviews with 3 groups (17 providers), and were analyzed according to the analytic method of Morgan (1998) and Krueger (1998). Results: The following five categories were identified: difficulties in obtaining a list of children among vulnerable classes, difficulties in first contact with them, difficulties in up-to-date immunization, various difficulties according to the types of vulnerable family and suggestions of solution. These results indicated that there are many difficulties in providing expanded immunization service for children among vulnerable classes in terms of manpower, cooperation of departments in public health centers and linkages between health and welfare. Finally, the characteristics of the types of vulnerable family need to be elucidated. Conclusion: To increase immunization rates among children of vulnerable classes, policies need to be prepared at the public health organization itself and the linkages between health and welfare and need for hiring additional personnel.

Implementation of a function translator converting vulnerable functions for preventing buffer overflow attacks (버퍼 오버플로우 공격 방지를 위한 취약 함수 변환기 구현)

  • Kim, Ik Su;Cho, Yong Yun
    • Journal of Korea Society of Digital Industry and Information Management
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    • v.6 no.1
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    • pp.105-114
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    • 2010
  • C language is frequently used to develop application and system programs. However, programs using C language are vulnerable to buffer overflow attacks. To prevent buffer overflow, programmers have to check boundaries of buffer areas when they develop programs. But vulnerable programs frequently result from improper programming habits and mistakes of programmers. Existing researches for preventing buffer overflow attacks only inform programmers of warnings about vulnerabilities and not remove vulnerabilities in advance so that the programs still include vulnerabilities. In this paper, we propose a function translator which prevents creating programs including buffer overflow vulnerabilities. To prevent creating binary from source including vulnerabilities, the proposed translator searches vulnerable functions which cause buffer overflows, and converts them into secure functions. Accordingly, developing vulnerable programs by programmers which lack in knowledge on security can be prevented.

Prioritization of Control Areas using Vulnerable Areas by Non-point Source Pollution (비점오염 취약지역을 고려한 관리우선순위 설정)

  • Kim, Hong Tae;Shin, Dong Seok;Kim, Yong Seok
    • Journal of The Korean Society of Agricultural Engineers
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    • v.56 no.6
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    • pp.11-18
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    • 2014
  • Vulnerable areas by non-point source pollution and prioritizing control areas were researched using hydrological and geomorphological data, non-point source loads, and water quality data. Using overlay analysis, vulnerable areas were graded with various scenarios. Vulnerable areas were selected near the metro city with impermeable landuse because non-point source loads and water quality data had influence on overlay analysis to rank vulnerable area. Analysis scenarios and weighted values can be changed under regional characteristics and given conditions.