• International Journal of Oral Biology
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• v.32 no.4
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• pp.143-151
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• 2007

This study was conducted to investigate the preventing effects of OPB (Rehmannia glutinosa Libosch and Eleutherococcus senticosus Max extracts) and combined OPB/Calcium therapy on bone loss in ovariectomized rats. Sixty Sprague Dawley rats of 12-week-old were divided into eight groups: OVX (ovariectomized), OPBL (OPB 50 mg/kg), OPBM (OPB100 mg/kg), OPBH (OPB 200 mg/kg), OPBL/CAL(OPBL+CAL), OPBM/CAL (OPBM+CAL), OPBH/CAL (OPBH+CAL) and CAL (Calcium citrate 88.33 mg/kg+1$\alpha$, 25-dihydroxy-vitamin $D_3$ 33.33 IU/kg). Bone mineral density (BMD), bone mineral content (BMC), bone strength indices and cortical thickness were analyzed by peripheral quantitative computerized tomography (pQCT). pQCT scanning showed that OVX induced a significant decrease in trabecular bone mineral density and bone mineral content in the proximal tibia $(-36.4\pm2.4%,\;-21.8\pm12.7%)$. These decreases were significantly prevented by the administration of OPBM and OPBM/CAL. Cortical BMD and BMC of tibia were slightly enhanced by OPB and OPB/CAL. However there was no significant difference between OVX and OPB, OPB/CAL treated group. Bone strength indices and cortical thickness were not significantly different. Our results suggest that OPB and combined OPB/Calcium therapy are effective in preventing the development of bone loss induced by ovariectomy in rats.

• Korean Institute of Interior Design Journal
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• v.26 no.6
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• pp.13-23
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• 2017

The purpose of this study is to analyze the expression method according to the planning of townhouse and the healing method that affects residents for communicating with natural environment, in order to propose resident-focused communication with nature for healing. The results are as follows. First, the expression of nature elements can be divided into 'direct' and 'indirect' and healing effects through nature can be divided into 'body' and 'psychology'. The healing method of residents through nature was classified into physical and psychological healing through openness, familiarity, comfort, and stability. Second, as an expression method according to townhouse planning, the arrangement plan induced active communication with nature through the arrangement according to topography and a common garden. In terms of construction plan, a bigger window or door than that of other residential spaces was installed on a wall, ceiling or opening to directly bring the nature of outside visually for more communication. Third, with regard to healing methods of townhouse, 'openness' which reduces depression and increases self-esteem, expands the view of residents. 'Familiarity', the healing method that can relieve the fatigue of eyes and bring psychological warmth and comfort, makes us feel familiar through the pattern and texture of woods and stones that are natural materials. 'Comfort' which heals residents by creating an outside space and bringing the nature elements through a huge window can provide psychological healing such as eased tension in daily life as well as physical healing such as vitamin D synthesis and the recovery of physiological function. Also, 'Stability' gives a comfortable feeling by applying the colors of finishing materials inside or seeing the colors of surrounding nature as it is through big windows. Finally, in order to support the results of this study more objectively, a follow-up study conducting a survey on the residents of townhouse is needed.

• Journal of the Korean Dietetic Association
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• v.23 no.3
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• pp.223-239
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• 2017

This study was conducted to investigate the anthropometric data, serum profiles, nutrient intakes and diet quality of men in their 30s. The subjects were divided into a married group and an unmarried group. For the study, we obtained data for analysis from the combined 2008~2015 Korean National Health and Nutrition Examination Survey (KNHANES). Mean height and weight of study population were 173.5 cm, and 74.0 kg in the married group and 173.1 cm, and 73.6 kg in the unmarried group, respectively. Systolic blood pressure in the unmarried group was significantly higher than that of the married group (P<0.001), while circulating vitamin D levels in the married group were significantly higher than those of the unmarried group (P<0.001). The proportion of obesity in the two groups was 42.41% and 38.40%, respectively. In the unmarried group, prevalence of depression was significantly higher than that those of the married group. Intakes of energy, water, protein, fat, carbohydrate and calcium in the married group were significantly higher than those of the unmarried group. In both groups, water and fiber intakes were low and sodium intakes were extremely high based on the KDRIs (Dietary Reference Intakes for Koreans). The mean adequacy ratio (MAR) of the married group was higher than that of the unmarried group. The index of nutritional quality (INQ) in the married group was also higher than that of the unmarried group. Therefore, we propose development of dietary guidelines and education programs for improvement of food and nutrient intakes, nutrition balance and dietary quality of unmarried men in their 30s.

• Journal of the Korean Dietetic Association
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• v.24 no.1
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• pp.48-61
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• 2018

This study was conducted to investigate the anthropometric data, serum profiles, food intakes frequency, and nutrient intakes of women aged 30-49 years. The subjects were divided into two groups: drinking group and non-drinking group. For the study, we obtained data for analysis from the combined 2008-2015 Korean National Health and Nutrition Examination Survey (KNHANES). Height and weight were 159.2 cm and 58.1 kg in the drinking group as well as 158.1 cm and 57.7 kg in the non-drinking group, respectively. Obesity percentage in the two groups were 22.5% and 24.8%, respectively. HDL-cholesterol (P<0.001) and Vitamin D (P=0.0248) levels in the drinking group were significantly higher than those of the non-drinking group. In the drinking group, rates of hypertension, myocardial infarction, and diabetes were significantly lower than those of the non-drinking group. Food and nutrient intakes, including energy, water, protein, fat, retinol, thiamin, riboflavin, and niacin, in the drinking group were significantly higher than those of the non-drinking group. In the two groups, energy, water, fiber, calcium, and potassium intakes were low while Na intakes were extremely high considering KDRIs (Dietary Reference Intakes for Koreans). The mean adequacy ratio (MAR) in the two groups was not significant.

• Korean Journal of Plant Resources
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• v.25 no.5
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• pp.507-516
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• 2012

Kidney stones occur in approximately 1% of the population during their lifetime. Although the development of extracorporeal shock wave lithotripsy (SWL) has revolutionized the theraphy of urolithiasis, the rate of recurrence of urothiasis, the rate of recurrenece of stones after SWL is about 50% within 10 years, which still represents serious problems for patienes. So to clarify the mechanism of Urocalum, and QS (Quercus salicina Blume) extract in the treatment of urolithiasis. Rat calcium oxalate urolithiasis was induced by oral administration of ethylene glycol and the vitamin D3 analog alfacalcidol for 14 days and QS extract was given to rats. After the last administration, we measured in urine, serum and renal oxidative stress marker. Ethylene glycol and alfacalcidol treatment increased BUN, creatinine, uric acid and XO. This increase was significantly suppressed by the administration of QS extract. These finding suggest that the QS extract plays a role in the prevention of stone formation and recureence in urolithiasis.

• KSBB Journal
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• v.26 no.5
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• pp.393-399
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• 2011

Bacillus subtilis natto producing high level of a fibrinolytic enzyme was selected and Ultra Nattokinase$^{(R)}$ was manufactured by fermentation and purification. It was performed the evaluation of the antithrombotic effect of Ultra Nattokinase$^{(R)}$ (20,000 FU/g) with rat blood plasma. The maximum aggregation (inhibition ratio) was 71% (0%), 69% (2.8%), 62% (12.7%), 16% (77.5%) and 9% (87.3%), respectively, in the order of 0, 5, 10, 50 and 100 mg/mL of Ultra Nattokinase$^{(R)}$ solutions. Ultra Nattokinase$^{(R)}$ had antithrombotic effect, which was associated with the suppression of collagen-induced platelet aggregation. Ultra Nattokinase$^{(R)}$ in the topic of the FDP (fibrinogen degradation products) in blood coagulation tests showed a significant increasing trend. And based on the daily record of meal 39 people of ITT (what ?) group consisted with 19 people of NP (what ?) group and 20 people of PN (what ?) group except four people, two people who took vitamin K affecting the experiment and two people who took alcohol, finding to be taken Ultra Nattokinase$^{(R)}$ showed an increase in the FDP value after four weeks. In addition, FDP value of 41 people of ITT group except two people having metabolic syndrome was increased by Ultra Nattokinase$^{(R)}$.

• Journal of Dairy Science and Biotechnology
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• v.34 no.3
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• pp.145-155
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• 2016

Cow's milk and dairy products are elements of the human diet that could play an important role in improving human health. The macronutrients and micronutrients found in milk could supply the nutrients required to maintain human health. Among them, milk-derived bioactive peptides have been identified as potential ingredients found in health promoting functional foods. These bioactive peptides target diet-related chronic diseases, particularly non-communicable ones such as cardiovascular disease, diabetes and obesity. Additionally probiotics such as lactic acid bacteria (LAB) are can be considered live microorganisms that confer health benefits for the host-, when administered in adequate amounts. Further, the calcium, vitamin D, and protein content of milk and dairy products could play a role in proving bone health. The effect of milk and calcium on bone mineral density could prevent against fracture, osteoporosis and rickets. Furthermore, milk and dairy products also contain which factors that, which protect against dental caries (anti-cariogenic properties). This paper reviews the various nutritional functions of milk and dairy products in improving human health.

• Journal of Bio-Environment Control
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• v.9 no.2
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• pp.79-84
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• 2000

The growth and quality differences between common thyme(Thymus vulgaris L.) and lemon thym (Thymus$\times$citriodorus) were investigated. They were grown in a hydroponics culture system (DFT) with a nutrient solution developed by the European Vegetable R&D Center in Belgium. Nutrient solution ionic strength used were 1.2, 2.4, 4.8 and 7.2 mS.cm-1. The dry matter of two thymes were increased with increasing ionic strength, while shoot length, root length and fresh weight were decreased. Chlorophyll content was higher in lemon thyme, while vitamin C content and essential oil content were higher in common thyme. The essential oil content showed a similar trend as those of growth. The main compostion of essential oil were thymol and carvacrol in common thyme, and geraniol and $\alpha$-citral in lemon thyme. The highest content of these compounds was obtained in 1.2mS.cm-1 treatment. Consequently, the ionic strength of 1.2mS.cm-1 was suitable for the production of quality thymes.

• Nutrition Research and Practice
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• v.14 no.1
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• pp.55-61
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• 2020

BACKGROUND/OBJECTIVES: Osteoporosis is characterized by low bone mass and results in vulnerability to fracture. Calcium and vitamin D are known to play an important role in bone health. Recently, potassium has been identified as another important factor in skeletal health. We examined the link between potassium intake and bone health among the Korean older adult population. SUBJECTS/METHODS: This retrospective, cross-sectional study included 8,732 men and postmenopausal women over 50 years old who completed the Korean National Health and Nutrition Survey (KNHANES) between 2008 and 2011. Potassium consumption was evaluated using a 24-hour recall method. Bone mineral density (BMD) was measured at three sites (total hip, femur neck, and lumbar spine) by dual-energy X-ray absorptiometry (DEXA). Multinomial logistic regression was used to examine the link between potassium intake and prevalence of osteoporosis and osteopenia, after controlling for potential confounding variables. RESULTS: The BMD of the total femur and Ward's triangle were significantly different according to the potassium intake among men (P = 0.031 and P = 0.010, respectively). Women in the top tertile for potassium intake showed higher BMD than those in the bottom tertile at all measurement sites (all P < 0.05). Daily potassium intake was significantly related to a decreased risk of osteoporosis at the lumbar spine in postmenopausal women (odds ratios: 0.68, 95% confidence interval: 0.48-0.96, P trend = 0.031). However, the dietary potassium level was not related to the risk of osteoporosis in men. CONCLUSION: Current findings indicate that higher dietary potassium levels have a favorable effect on bone health and preventing osteoporosis in older Korean women.

• Korean Journal of Community Nutrition
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• v.3 no.4
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• pp.622-629
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• 1998

This study was performed to investigate the effect of dietary intakes and nutritional status for fatty liver male patients with fatty livers. General characteristics, nutritional knowledge, and dietary intakes were obtained from fatty liver male patients aged 20-60yr living in Seoul and Kyunggi province by individual interview and blood samples. The Results were as follows : the mean age of the subjects was 39yrs. Old and over half the subjects were overweight. Although nutritional knowledge, recognition, and accuracy scores were good, these did not affect the subject's health. The average alcohol intake of subjects was 79.8g/day and the drinking duration was 5-40yrs(average : 17yrs). The subjects drank alcohol over 4tiles/week and preferred Soju. Most side dishes taken with alcohol drinking by the subjects were foods from animal sources. Half of the subjects also drank alcohol the next day for breakfast as a hangover-chaser. The reasons for drinking were due to social relationships and by habit. Vitamin D and folate were lower than the RDA for Koreans, and other nutrient amounts were higher than the RDA. The amounts of aspartate amino-transferase(AST), Alanine amino-transferase(ALT), ${\gamma}$-glutamyl transpeptidase(${\gamma}$-GTP), Triglyceride(TG) for the subjects were higher. In conclusion, fatty liver patients drank excessively and frequently. It seems that heavy alcohol drinking is more prone to overweight or obese people and contributes to fatty livers. Therefore, the subjects need to be taken effectively educated about alcohol-induced liver damage and the importance of a balanced diet for on healthy liver.