• 생물정신의학
• /
• 제21권2호
• /
• pp.65-73
• /
• 2014

Objectives This study aimed to identify the differences and the profiles of cognitive deficits in remitted patients with schizophrenia and first-degree relatives of schizophrenic probands. Methods A total of 26 remitted states of schizophrenia patients were included in the study and the same number of unaffected first-degree relatives of schizophrenic probands and healthy controls were matched for age, sex, years of education. Cognitive function of all participants was measured by using the Digit span test, the Continuous performance test, the Rey auditory & visual learning test, the Complex figure test, the Verbal fluency test, the Wisconsin card sorting test and the Finger tapping test. The effects of subsyndromal symptomatology and general intelligence score were controlled. Results Schizophrenia patients' group showed more significant impairment than other groups in verbal memory (learning, immediate recall, delayed recall), visual memory (copy, immediate recall, delayed recall) and cognitive flexibility domains. The family group and the patient group commonly performed significantly worse than healthy controls in working memory and verbal fluency (category) tests. There were no differences in sustained attention, psychomotor performance. Conclusions Our research shows that the deficit in working memory and verbal fluency could be strong candidates of endophenotypic marker in schizophrenia.

• 한국의료질향상학회지
• /
• 제5권1호
• /
• pp.120-127
• /
• 1998

Background : This study is to identify preoperative patient characteristics associated with a lack of improvement on one or more measures peri operatively, postoperative 3-4 months, and postoperative 12 months. Methods : For the assessment, prospective study was performed with 92 patients who had undergone either one eye or both eye cataract surgery by 3 ophthalmologists practicing at a university hospital. The criteria of improvement were (1) Snellen visual acuity, (2) a cataract-related symptom score(possible range: 0, 0 of 6 symptoms present or bothersome, to 18, all 6 symptoms very bothersome), and (3) VF-14 score - a measure of functional impairment in patient with cataract - (possible range: 0, inability to perform any of the applicable activities, to 100, no difficulty in performing any of the applicable activities). Results : Although 14 patients (15.2%) failed to improve on one or more of the outcome measures assessed, no one failed to improve on all three measures. Both eyes of surgery than one eye, preoperative cataract symptom score of 1-4, 5 or higher than 0 were associated independently with the increased likelihood of improvement (odds ratio 8.95, 7.16, 8.87 respectively). And the preoperative level of Snellen visual acuity was not associated with the likelihood of improvement Conclusion : We conclude that specific preoperative characteristics (both eyes, cataract symptom score) are independent predictors of patient outcome after cataract surgery.

• 한국정보통신학회:학술대회논문집
• /
• 한국정보통신학회 2017년도 추계학술대회
• /
• pp.391-394
• /
• 2017

저시력 장애인은 선천적 혹은 후천적인 안질환으로 인한 의학적 안광학적 방법으로 개선이 불가능한 시력 장애 및 시기능 장애를 말한다. 저시력 장애인은 전 세계에 2억 4000만 명에 해당할 만큼 많은 비율을 차지하고 있으며 잔존시력이 있음에도 불과하고 스마트 시대에 정보 취약 계층에 속하고 있다. 기존 스크린리더(TTS) 및 화면확대 기능을 통해 정보접근이 가능한 환경에서 저시력 장애인을 위한 모바일 웹 환경에서의 UI/UX에 대한 연구를 통해 저시력 장애인의 정보 접근성 향상 및 향후 연구 방안에 대해서 논하고자 한다.

• 한국컴퓨터정보학회논문지
• /
• 제26권11호
• /
• pp.191-199
• /
• 2021

본 연구는 노인운전자의 운전 면허를 갱신 할 때 필요한 추가 검사를 제안할 목적으로 실시되었다. 우리나라에서는 고령 인구가 빠르게 증가하면서 고령 운전자의 비율이 높아지고 있다. 전반적으로 교통사고율이 감소하고 있지만, 고령 운전자에서는 교통사고율과 교통사고로 인한 사망률이 증가하고 있다. 본 연구에서는 우리나라에서 실시하고 있는 고령 운전자의 운전면허 갱신 시 실시하고 있는 검사와 교육을 알아보고 외국의 현황과 비교하여 필요한 검사를 알아보기 위해 시행했다. 운전능력과 관련된 신체기능은 크게 시각, 인지, 운동 및 체성감각의 세 영역에 대해 평가하는 것이 적절하지만, 현재 우리나라에서는 시각 중 시력만을 평가하고 있고, 인지 영역에서는 경증 인지 손상은 알아볼 수 없는 MMSE-K와 시계 그리기 검사만을 진행하고 있다. 운전을 수행하는 운동능력에 대해서는 전혀 평가하고 있지 않다. 따라서 고령 운전자의 안전운전을 위해서는 운전면허 갱신 시 실시하는 검사에 시각에서는 시야와 대조대비력 검사, 인지 기능에서는 경증 인지장애를 구별할 수 있는 검사, 운동기능을 평가하기 위한 검사를 보완해야 할 것이다.

• 대한의생명과학회지
• /
• 제24권4호
• /
• pp.418-425
• /
• 2018

Amyloid brain positron emission tomography (PET) images are visually and subjectively analyzed by the physician with a lot of time and effort to determine the ${\beta}$-Amyloid ($A{\beta}$) deposition. We designed a convolutional neural network (CNN) model that predicts the $A{\beta}$-positive and $A{\beta}$-negative status. We performed 18F-florbetaben (FBB) brain PET on controls and patients (n=176) with mild cognitive impairment and Alzheimer's Disease (AD). We classified brain PET images visually as per the on the brain amyloid plaque load score. We designed the visual geometry group (VGG16) model for the visual assessment of slice-based samples. To evaluate only the gray matter and not the white matter, gray matter masking (GMM) was applied to the slice-based standard samples. All the performance metrics were higher with GMM than without GMM (accuracy 92.39 vs. 89.60, sensitivity 87.93 vs. 85.76, and specificity 98.94 vs. 95.32). For the patient-based standard, all the performance metrics were almost the same (accuracy 89.78 vs. 89.21), lower (sensitivity 93.97 vs. 99.14), and higher (specificity 81.67 vs. 70.00). The area under curve with the VGG16 model that observed the gray matter region only was slightly higher than the model that observed the whole brain for both slice-based and patient-based decision processes. Amyloid brain PET images can be appropriately analyzed using the CNN model for predicting the $A{\beta}$-positive and $A{\beta}$-negative status.

• 감성과학
• /
• 제23권4호
• /
• pp.73-92
• /
• 2020

본 논문은 시각장애인의 문화향유권 확대를 위하여 현재 비중 있게 다루어지지 않고 있는 감각인 후각을 사용한 새로운 미술작품 감상법 개발의 가능성에 대하여 다루고 있다. 인간의 후각은 현대사회에서는 크게 중요시되지 않는 감각이지만 이는 문화적인 요인에 의한 것이며, 생물학적인 관점에서 후각은 실용적 활용 가능성을 충분히 지닌 감각이다. 본 연구에서는 여러 종류의 향이 후각을 통하여 인지될 때 각각 고유의 색상 및 개념과 무의식적인 연관 관계를 지니고 있음을 가정하였고, 이를 향의 색 지향성과 개념 지향성이라는 용어로 나타내었다. 연구자들은 실험을 통하여 특정한 일부 향에 색 지향성과 개념 지향성이 존재함을 확인하였고 이러한 향을 활용하여 시각장애인들에게 미술작품에 사용된 색상에 대한 정보를 전달하는데 성공하였다. 본 연구를 기반으로 색채가 지닌 명도와 채도 및 더 다양한 색상을 전달할 수 있는 색-개념 지향성 향의 활용에 관한 연구를 지속할 수 있기를 희망한다.

• 한국의류산업학회지
• /
• 제24권5호
• /
• pp.647-654
• /
• 2022

Wearable devices come in a variety of shapes and sizes in numerous fields in numerous fields and are available in various forms. They can be integrated into clothing, gloves, hats, glasses, and bags and used in healthcare, the medical field, and machine interfaces. These devices keep track individuals' biological and behavioral data to help with health communication and are often used for injury prevention. Those with hearing loss or impaired vision find it more difficult to recognize an approaching person or object; these sensing devices are particularly useful for such individuals, as they assist them with injury prevention by alerting them to the presence of people or objects in their immediate vicinity. Despite these obvious preventive benefits to developing Internet of Things based devices for the disabled, the development of these devices has been sluggish thus far. In particular, when compared with people without disabilities, people with hearing impairment have a much higher probability of averting danger when they are able to notice it in advance. However, research and development remain severely underfunded. In this study, we incorporated a wearable detection system, which uses an infrared proximity sensor, into a backpack. This system helps its users recognize when someone is approaching from behind through visual and tactile notification, even if they have difficulty hearing or seeing the objects in their surroundings. Furthermore, this backpack could help prevent accidents for all users, particularly those with visual or hearing impairments.

• 재활복지공학회논문지
• /
• 제9권3호
• /
• pp.185-193
• /
• 2015

본 연구의 목적은 임상에서 사용하고 있는 뇌 자극 훈련인 N-BACK 프로그램을 뇌졸중 환자들에게 적용하여 인지, 시지각, 우울, 불안과 일상생활활동에 미치는 임상적 효과를 증명하고자 하는 것이다. 이를 증명하기 위해 뇌졸중으로 진단받고 유병기간이 6개월 이상인자로 한국판 정신상태판별검사(MMSE-K)에서 18~23점으로 인지기능 손상이 의심되는 자로써 무작위로 실험군과 대조군 각각 10명씩 선정하였다. 연구자 1인의 진행 하에 임상경력 5년 이상의 숙련된 치료사 8명에 의해 연구가 진행되었으며, 4주간 주 5회 1일 30분, 총 20회를 실시하였다. 그 결과 뇌졸중 환자에게 뇌 자극 훈련인 N-BACK 프로그램을 적용한 실험군이 대조군보다 인지, 시지각, 우울, 불안과 일상생활활동 기능 향상에 긍정적인 결과를 보였다. 이 연구로부터 얻은 결과들은 뇌졸중 환자의 인지, 시지각, 우울 및 불안의 향상을 위해 N-BACK 프로그램을 적용하면 환자의 재활에 긍정적인 효과가 있음을 기대할 수 있고, 그로 인해 일상생활 활동이 보다 독립적으로 향상될 것으로 기대할 수 있다.

• Parasites, Hosts and Diseases
• /
• 제38권4호
• /
• pp.267-273
• /
• 2000

We report 5 cases of ocular toxocariasis in Korean adults complaining of visual impairment along with floating or bubbling sensation. Fundoscopic examination revealed a retinal detachment along with exudate in 4 cases. They all showed typical reaction by ELISA and immunoblot against Toxocra excretory-secretory antigen. One case showed high level of anti-Toxocara IgE antibodies (34.000 Toxocara units/L) as well as increased level of serum total IgE antibodies and the specific IgE antibodies for 3 inhalant antigens, suggesting that high level of anti-Toxocara IgE antibodies was associated with an atopic status. Clinical manifestations were improved after the sequential use of steroids then mebendazole. We also suggest that ocular toxocariasis should be thoroughly investigated even when an evocative uniocular inflammatory lesion is encountered in peripheral retina without a systematic disease.

• 근관절건강학회지
• /
• 제24권2호
• /
• pp.67-76
• /
• 2017

Purpose: The purpose of this study was to evaluate preoperative nutritional status in elderly patients with orthopedic surgery and identify related factors for malnutrition risk. Methods: This study enrolled 337 patient's medical record who underwent orthopedic surgery in hospital between January and December 2015. Data was collected retrospectively. Nutritional status was evaluated by using the Nutritional Risk Screening 2002. Multivariable logistic regression analysis was used to identify independent related factors for malnutrition risk. Results: Malnutrition risk developed in 58 patients (17.2%). Logistic regression analysis identified low physical activity, visual impairment, depression, sleep disorder, low serum calcium level, and low serum albumin level as related factors. Conclusion: Orthopedic surgery in elderly patients was associated with high risk of preoperative malnutrition. The results of this study suggest that evaluating the nutritional status and related factors should be done with preoperative status of elderly patients. At the same time, interventions for nutritional care should be adjusted to meet the nutritional needs of individuals and decrease the risk of malnutrition.