• The Korean Journal of Pain
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• v.29 no.2
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• pp.96-102
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• 2016

Background: It is widely accepted that cervical interlaminar steroid injection (CIESI) is more effective in treating radicular pain than axial neck pain, but without direct comparison. And the differences of effect after CIESI according to MRI findings are inconsistent. In this retrospective study, we evaluated the therapeutic response of CIESI according to pain sites, durations, MRI findings, and other predictive factors altogether, unlike previous studies, which evaluated them separately. Methods: The medical records of 128 patients who received fluoroscopy guided CIESI were analyzed. We evaluated the therapeutic response (more than a 50% reduction on the visual analog scale [VAS] by their second visit) after CIESI by (1) pain site; neck pain without radicular pain/radicular pain with or without neck pain, (2) pain duration; acute/chronic (more than 6 month), and (3) findings of MRI; herniated intervertebral disc (HIVD)/spinal stenosis, respectively and altogether. Results: Eighty-eight patients (68%) responded to CIESI, and there were no significant differences in demographic data, initial VAS score, or laboratory findings. And there were no significant differences in the response rate relating to pain site, pain duration, or MRI findings, respectively. In additional analysis, acute radicular pain with HIVD patients showed significantly better response than chronic neck pain with spinal stenosis (P = 0.04). Conclusions: We cannot find any sole predictive factor of therapeutic response to the CIESI. But the patients having acute radicular pain with HIVD showed the best response, and those having other chronic neck pain showed the worst response to CIESI.

• Journal of The Korean Society of Integrative Medicine
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• v.3 no.4
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• pp.11-21
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• 2015

Purpose : The purpose of this study was to provide the material about the treatment effect of hand function training and writing training being performed as a part of treatment to improve the function of the non-dominant hand of the patients whose dominant hand is damaged and thus need to improve their non-dominant hand's function. Method : During one month of November, 2013, this study randomly chose five study subjects for hand function training, five for writing training, and ten of control group from 20 normal male and female adults going to K Univ. in Busan. All study subjects fully understood all of the training course, agreed to take the test in this study, and volunteered to participate in the test. Each training was performed five times for two weeks, 30 minutes each time. For measurement, Purdue pegboard was used to look into the change of hand dexterity. To investigate an improvement in hand function through hand function training and writing training, this study conducted early evaluation before training, interim evaluation, and final evaluation. Result : First, according to the comparison of dominant hand dexterity by group and by method during a training period, the groups of hand function training and of writing training improved dominant hand dexterity more than the control group. Secondly, according to the comparison of non-dominant hand dexterity by group during a training period, the groups of hand function training and of writing training improved dexterity more than the control group. According to the comparison of non-dominant hand dexterity by method during a training period, there was no big difference in dexterity between the groups of hand function training and of writing training and the control group. But, the group of hand function training showed a further improvement. Thirdly, according to the comparison of both-hand dexterity by group and by method during a training period, the groups of hand function training and of writing training improved both-hand dexterity more than the control group. Fourthly, according to the comparison of both-hand handling ability by group and by method during a training period, the groups of hand function training and of writing training improved both-hand handling ability more than the control group. Conclusion : Given the study result, it is considered that hand function training and writing training help brain damaged patients improve their hand function for their daily activity. And it will be meaningful to research brain damaged patients' motor skills after their brain damage, and the patients who have low abilities of visual perception and cognition. In the future, it will be necessary to secure more study subjects and perform systematic training during a sufficient test period.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.36 no.4
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• pp.281-288
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• 2010

In this study, we investigated anti-oxidative effects of Duchesnea indica extracts by using Oxygen Radical Absorbance Capacity (ORAC). The extracts were prepared with 0 %, 30 %, 50 %, 70 % and 100 % aqueous ethanol respectively. The 30 % EtOH D. indica extract showed higher ORAC activity than the other extracts. Therefore, we performed in vitro studies on cytotoxicity of NIH-3T3 cells and MMP-8 collagenase inhibition using by the 30 % EtOH extract. The 30 % EtOH extract showed no cytotoxicity and significant inhibition on MMP-8 collagenase. And we performed clinical studies for the anti-wrinkle effect of the Di-Wrinkle Free Cream. The cream formula was prepared with 2 % arbutin and 1 % D. indica extract. Twenty one healthy women volunteers, ages of 35 and 50, applied the cream on their faces twice a day for 8 weeks. The skin was evaluated with PRIMOS (phaseshift rapid in vivo measuring of human skin) system and analyzed by the student's paired t-test. The wrinkles on the eye region were reduced by 13 % based on the PRIMOS system after 8 weeks. In the safety study of the Di-Wrinkle Free Cream, no symptoms were observed such as erythema, edema, scaling, itching, stinging, burning, tightness and prickling by visual observation and medical examination of volunteers for 8 weeks. Moreover, there was no noticeable skin disorder during experience period. These results suggested that D. indica extracts could be applied as cosmeceuticals effective for anti-wrinkle.

• Journal of Digital Convergence
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• v.11 no.3
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• pp.337-344
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• 2013

This research has been conducted to determine the effect that the visually handicapped's participation in an aerobic exercise program has on cardiorespiratory function and arterial pulse wave. The subjects of this research were 20 people who have a 1st degree visual impairment. They recognized the purpose of this research and agreed to take part in it. After receiving agreements from their guardians, we divided them into an exercise group of 10 and a comparison group of 10 at random. The exercise group conducted a 50-70%HRmax treadmill exercise for 60 minutes a day, five times a week, for 12 weeks, including warm up and warm down exercises. We then conducted a two-way repeated ANOVA, which regards the period of exercise and the two groups as independent variables. The follow-up verification for exercise periods according to each group was carried out with a paired t-test. The statistical significance level was p<.05. The following are the results of this research. First, the weight and body fat of the experiment group after exercise show a meaningful reduction compared to before the exercise program (p<.05).Second, the VO2max, HRmax, and VEmax of the experiment group after exercise show a meaningful increase compared to before the exercise program (p<.05). Third, the arterial pulse wave of the experiment group after exercise display a meaningful increase compared to before the exercise program (p<.05). Fourth, the systolic blood pressure of the experiment group after exercise does not show a meaningful reduction compared to before the exercise program (p>.05). These results prove that the visually handicapped's participation in an aerobic exercise program is effective in the improvement of their cardiorespiratory function, bloodstream circulation function and blood vessel function.

• Journal of the Korean Institute of Landscape Architecture
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• v.45 no.1
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• pp.82-93
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• 2017

The purpose of this study is analyze the impact on users' cognition of design concept, satisfaction of design concept, adapted park space, and effect of design concepts on park use satisfaction. The study sites are Central Mountain Park and Lake Park in Gwanggyo New Town, Suwon. We analyzed importance-satisfaction of park facilities in the park and preference-satisfaction of park. The results of this study are as follows. First, generally users visit the park as a family unit. Second, trails got high scores in importance-satisfaction of park facilities. Third, park users' satisfaction received a high score generally, but it doesn't show statistic significance with users' cognition of design concept. Fourth, cognition of the two parks' design concept and design strategy got a high score - over three points on average - based on the 5 - point Likert scale. However, upon analysis of users' cognition of design concept and satisfaction of design concept adapted park space, there is no statistic significance. Therefore, we noticed that the park's design concept had an effect on park users' satisfaction; rather, personal preference and satisfaction of users had more impact on satisfaction. On the other hand, this study was limited in that we didn't survey across all four seasons and had few target areas. But it has some significance in that we used a visual documentation, attaching existing photos including design concept, to increase users' understanding. Also, we directly asked about the parks' user design concept and strategy.

• Korean Journal of Weed Science
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• v.30 no.2
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• pp.143-152
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• 2010

Herbicidal characterisitcs of natural product chrysophanic acid were investigated in a greenhouse condition. At early- and middle-stage post-emergence treatments, several grasses and broadleaf weeds appeared to be very susceptible to chrysophanic acid. However, any significant herbicidal activity treated by pre-emergence did not occur at concentration ranges from 31.3 to 1,000 ug $mL^{-1}$. Herbicidal activity of chrysophanic acid estimated by visual injury for large crabgrass was much higher when applied at 7 to 14 days after seeding than at 21 and 28 days after seeding. By post-emergence treatment, chrysophanic acid caused very considerable phytotoxicity on several grasses and broadleaf crops. In herbicidal interaction experiments determined by Colby's method, the effect of chrysophanic acid and caryophyllene oxide tank-mixture showed very high synergistic activity. Although chrysophanic acid did not give any pre-emergence effect, herbicidal spectrum tended to be very wide and strong when treated by post-emergence. These results suggest that chrysophanic acid possesses a possible potential to develop as a natural herbicide.

• Journal of Korean Ophthalmic Optics Society
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• v.19 no.4
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• pp.505-511
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• 2014

Purpose: This study was to investigate the effect of breath alcohol concentration (BrAC) increase with drinking alcohol on contrast sensitivity in the conditions of restricted BrAC. Methods: 23 males in 20s (average age $21.17{\pm}2.19$ years, body mass index (BMI) $22.09{\pm}2.16$) were selected and administered the amount of alcohol to reach 0.05% and 0.08% BrAC calculated by BAC (blood alcohol concentration) Dosing Software program, which was developed as basis of Watson's formula. Then, the contrast sensitivity in various luminance conditions (photopic, mesopic, and mesopic with glare) was measured and compared between these conditions. Results: The contrast sensitivity in all spatial frequency was decreased with BrAC increase. Although BrAC was increased, the peak of contrast sensitivity didn't change as 6 cycle per degree (cpd) in the photopic condition and 3 cpd in the mesopic condition, respectively. But, in the mesopic condition with glare, the peak of contrast sensitivity was shifted from 6 cpd at 0% and 0.05% BrAC to 3 cpd at 0.08% BrAC with increase of alcohol concentration. Conclusions: The increase of BrAC by drinking alcohol induces the decrease of contrast sensitivity in all spatial frequency and the shift of peak of contrast sensitivity, which can cause safety accidents, and may have an effect on various visual tasks.

• The Korean Journal of Pain
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• v.22 no.2
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• pp.130-134
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• 2009

Background: The advances in surgical technology, anesthesia and perioperative care have made it possible to perform laparoscopic cholecystectomy on an outpatient basis. This study was conducted to assess the analgesic effect and the adverse events of different dosing methods when using transdermal fentanyl patches (TDFPs) after laparoscopic cholecystectomy. Methods: Sixty patients who were to undergo laparoscopic cholecystectomy under general anesthesia were divided into two groups. Group 1: 2 TDFPs that released $12{\mu}g/h$ were applied after the induction of anesthesia and these 2 patches were removed after 24 hours. Group 2: 2 TDFPs that released $12{\mu}g/h$ were applied after the induction of anesthesia and one patch was removed after 7 hours and the other patch was removed after 24 hours. The intensity of the postoperative pain was assessed by using a visual analogue scale (VAS) and assessing the adverse events, including dizziness, pruritus and nausea/vomiting, were recorded for 48 hours postoperatively. Results: The VAS score of postoperative pain was not significantly different between the two groups at all times. The incidence of dizziness in groups I and II was 10 and 3, respectively, and the incidence of nausea/vomiting in group I and II was 4 and 0, respectively. The incidences of dizziness and nausea/vomiting in group II were significantly lower than those of group I (P<0.05). Conclusions: A dosing method that removes half of the TDFPs ($24{\mu}g/h$) after 7 hours of application caused a lower incidence of dizziness and nausea/vomiting without any significant difference of postoperative analgesic efficacy, as compared to leaving on both the TDFPs (24$\mu$g/h) for 24 hours after laparoscopic cholecystectomy.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.33 no.2
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• pp.79-86
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• 2007

The aim of this study was to investigate the inhibitory effects of Forsythia suspensa fruit extracts (FSfE) ($0.1{\sim}1.0%$) and their active component on melanogenesis. FSfE dose-dependently inhibited melanin synthesis (up to $63.1{\pm}3.1%$ at the concentration of 1.0%) without cell cytotoxicity. We purifed one active compound from FSfE and identified its structure. It was identified as 4-[(3,4-Dimethoxyphenyl)methyl)]dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone (arctigenin) by $^1H-NMR,\;^{13}C-NMR$, and Mass analysis. Arctigenin also inhibited melanin synthesis in a dose dependent manner (up to $52.7{\pm}3.1%$ at the concentration of $3.0{\mu}g/mL$). In order to verify the whitening activity of the cream containing 3% FSfE, we performed the clinical test with twenty five female volunteers for 8 weeks. Bioengineering analyses and visual assessment by doctors at the initial time point and 8 weeks after applications showed that cream containing FSfE have significant whiteining effect (paired t-test). From the results, we conclude that the FSfE can be used as a useful whitening agent.

• Journal of Acupuncture Research
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• v.23 no.5
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• pp.219-228
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• 2006

Objectives : To observe the effect of acupuncture treatment on Digital Infrared Thermographic Imaging(DITI) in frozen shoulder patients. Methods : 17 voluntary patients received acupuncture treatment on LI15, TE14, GB21 and Master Dong's acupuncture points, Shin-gwan and Gyun-joong, twice a week for 4 weeks. The patients were instructed to practice self exercise during their daily lives. Evaluations were made before treatment, after 1 week of treatment, after 2 weeks, 3 weeks and after 4 weeks of treatment. Constant Shoulder Assessment(CSA), Shoulder Pain and Disability Index(SPADI), Range of Motion(ROM) and the patient's satisfaction concerning the treatment was measured by Visual Analogue Scale(VAS). DITI was measured before treatment and after 4weeks of treatment. The obtained data was analyzed. Results : CSA, SPADI, VAS, adduction and extension showed significant(p<0.05) improvement. Abduction and flexion both improved after 4 weeks of treatment, but the improvement was statistically insignificant(p>0.05). DITI showed improvement but the improvement was insignificant(p>0.05). Conclusion : 4 weeks of acupuncture treatment significantly improved CSA, SPADI, VAS, adduction and extension in frozen shoulder patients(p<0.05). The improvement of abduction and flexion after 4 weeks of acupuncture treatment was insignificant(p>0.05). DITI results improved after 4 weeks of acupuncture treatment. But the change of thermal difference was insignificant(p>0.05).