• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.13 no.2
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• pp.35-46
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• 2018

Objectives : To determine the effectiveness of Chuna manual therapy(CMT) for Adult Visceral Diseases. Methods : To find evidence of CMT for adult digestive system disease, we used 9 electronic databases(Pubmed, CAJ, EMBASE, Cochrane Library, Web of Science, KISS, KISTI, NDSL, RISS) up to April 2018. We reviewed randomized control trials(RCTs) using Chuna for Digestive system disease. To assess the methodological quality of each RCT, we used the Cochrane risk of bias tool. Results : We identified 11 RCTs about irritable bowel syndrome, chronic ulcerative colitis, gastritis, gastroptosis, spleen entropathy, gastrointestinal dysfunction after stroke in 356 studies. All studies used total efficiency rate for main outcome. In all studies, CMT was effective for digestive system disease. Conclusions : CMT was effective for Digestive system disease. Risk of bias was high and the difference between the experimental group and the control group was not great. Considering that there were no reports of side effects, it seems possible to apply CMT to the treatment of adult digestive system disease.

• Journal of Korea Association of Health Promotion
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• v.2 no.1
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• pp.77-83
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• 2004

Recently, peoples of travelling to endemic area of parasitit diseases are rapidly increased and the imported parasitic diseases by tourists have become a public health problem. Here author describess briefly about the imported parasitic in Korea. The 15 kinds of parasitic diseases, I.e., malaria, babesiosis, cutaneous leishmaniasis, visceral leishmaniasis, ancylostomiasis, cutaneous larva migrans, angiostrongylosis, gnathostomiasis,loiasis, heterophyiasis, urinary schistosomiasis, hydatis disease, pentastomiasis, cutaneous myiasis and syngamosis were imported during last thirty years. The most prevalent imported parasitic disease was malaria. Indigenous vivax malaria has been eradicated since 1970s. However imported malaria(1970~1985) was reported 107 cases of patient with a history of travel abroad. Futhermore a case of reemerging vivax malaria was patient were occurred in 2000.These parasitic disease are sometimes overlooked or misdiagnosed. There is a need to concern about travel medicine and imported parasitic diseases.

• Journal of Korea Association of Health Promotion
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• v.3 no.1
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• pp.46-54
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• 2005

The functional dyspepsia is a complex disease reaction that ocurs due to the presence of various factors and its pathophysiology has not been clearly verified until now. This disease is diagnosed after the organic diseases are ruled out. Therefore, the main treatments are limited down to compensating for revealed symptoms through exercising the supportive care. The international prevalence of the functional dyspepsia under the Rome I criterior is approximately 25%. For the cases of Koreans, there are very omnifarious symptoms in gastrointestinal disorders and the medical vocabularies which describe the diagnostic standard are not closely associated with the daily vocabularies, thus there would be a lot of restrictions to directly apply the Rome II criterior. However, the Korean Society of Gastrointestinal motility had decided to promote the use of the international standardized Rome II criterior in order for Korea to be comparable to the clinical studies from the other nations. There should be more extensive studies to differentiate the definitions of symptom descriptions from Korea to foreign countries. The extended researches concerning the pathophysiology are highly recommended which in return, would help enabling the reliable treatment techniques for this disease.

• Journal of mucopolysaccharidosis and rare diseases
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• v.5 no.1
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• pp.1-7
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• 2021

Gaucher disease (GD, OMIM #230800 OMIM#230800) is a rare, autosomal recessive inherited metabolic disorder caused by mutation in GBA1 encoding the lysosomal enzyme, glucocerebrosidase. The deficiency of glucocerebrosidase leads to an accumulation of its substrate, glucosylceramide in macrophages of various tissues. Common clinical manifestations include cytopenia, splenomegaly, hepatomegaly, and bone lesions. The phenotype of GD is classified into three clinical categories: Type 1 (non-neuronopathic) is characterized by involvements on the viscera, whereas types 2 and 3 (neuronopathic) are associated with not only visceral symptoms but also neurological impairment, either severe in type 2 or variable in type 3. A diagnosis of GD can be confirmed by demonstrating the deficiency of acid glucocerebrosidase activity in leukocytes. Mutations in the GBA1 should be identified as they may be of prognostic value in some cases. Biomarkers including Chitotriosidase, CCL18, and glucosylsphingosine (lyso-GL1) are useful in diagnosis and treatment monitoring. Currently available disease-specific treatment in Korea consists of intravenous enzyme replacement therapy and substrate reduction therapy. For enhancing long-term prognosis, the onset of Parkinson's disease and Lewy body dementia, or the occurrence of a blood disease or cancer (hepatocellular carcinoma) should be monitored in older patients. The development of new strategies that can modify the neurological phenotype are expected, especially in Asia including Korea, where the prevalence of neuronopathic GD is relatively higher than that in western countries.

• Journal of Chest Surgery
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• v.43 no.6
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• pp.747-752
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• 2010

Surgical repair of thoracoabdominal aortic aneurysm (TAAA) remains a formidable challenge associated with significant rates of mortality and morbidity, especially in patients with high risk. Use of endovascular stent graff in aortic aneurysm disease is now accepted as an alternative treatment to surgery. But the saving of visceral arteries is the chief obstacle to endovascular repair of TAAA. We successfully treated two patients of TAAA with high risk by hybrid procedure including open visceral debranching and concomitant endovascular aneurysm exclusion.

• YAKHAK HOEJI
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• v.50 no.3
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• pp.160-165
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• 2006

Germanium is found in a range of minerals and ores and is present in foods including beans, tomato juice, oysters, tuna and garlic. Germanium is a non-metallic element, which can exist in valence states of 2 and 4. Clinical trials and use in private practices for more than a decade have demonstrated organic germanium's efficacy in treating serious disease including cancer, arthritis and senile osteoporosis. But it was rarely reported that inorganic germanium has biological properties. STB-BM contains mineral complex, rare earth elements and a little amount of Inorganic germanium. The experiment was carried out the anti-obesity effect. To investigate anti-obesity effect of STB-BM, we measured the effect of body weight, fat weight (subcutaneous fat, epididymal fat, visceral fat, kidney fat and total fat) and serum biochemical level in rats fed high fat diets. STB-BM 35 mg/kg suppressed the increasing ratio of body weight, epididymal fat weight, visceral fat weight, total fat weight, triglyceride and LDL-cholesterol (p<0.05).

• Journal of Oriental Neuropsychiatry
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• v.12 no.2
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• pp.37-51
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• 2001

The clinical study was carried out the 43 patients with Depression who were treated in Department of Neuropsychiatry, College of Oriental Medicine, Dae Jeon University from 22 February 2000 to 14 November 2001. The results were summarized as follows. 1. The ratio of male and female was 10:33, 60's(32.6%) was frequent, no inducing factor(38.3%) was seen in a lot of cases and many patients came to our hospital by way of west-neuropsychiatry(56.8%). 2. The period of clinical history was frequent from 3 to 10 years(23.2%), the most frequent preceding disease was cardiovascular systemic disease(18.4%). 3. The main clinical symptoms were apprehension alpitation(13.4%), anorexia(9.8%), headache nuchal region stiffness(9.8%), general body weakness(6.5%), chest discomfort(6.5%), dizziness(5.7%), febris(5.3%) and constipation(5.3%). 4. The patient's tongue aspect had pink tongue and empty fur(32.6%) and pulse type had thin and deficient pulse(39.5%). The prescription drugs were Chunggansoyo-san(30.0%), purging liver and alleviating depression to regulate qi, and Guibiondam-tang(15.8%) eliminating phlegm, cooling pericardium and warming gallbladder. 5. The curve was within normal range at Psychoneural system(81.4%), and Visceral system(90.1%). 6. The regulation was Normal(48.1%), RL(27.9%), RR(20.2%) at Psychoneural system and Normal(45.9%), RL(28.5%), RR(20.3%) at Visceral system. 7. Activity and Reactivity had much lower response at 1th, 2th, 3th, 4th, 7th SANGHAN, Polalization had much higher response at 1th, 4th, SANGHAN and much lower response at 2th, 3th, 7th SANGHAN.

• Tuberculosis and Respiratory Diseases
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• v.45 no.3
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• pp.649-653
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• 1998

Pulmonary arteriovenous fistula is a congenital vascular malformation in lung resulting from abnormal capillary development and the exact etiology is not well known but it may occur with or without hereditary hemorrhagic telangiectasia. Hereditary hemorrhagic telangiectasia (HHT) or Rendu-osler-Weber disease is an autosomal dominant vascular disorder which associates epistaxis, mucocutaneous and visceral telangicetases, and recurrent hemorrhage with chronic anemia and visceral shuntings. Recently we experienced a case of the pulmonary arteriovenous fistula in a 23 year-old woman with a family history of this disease, which was confirmed by pulmonary angiography.

• Journal of Korean Medical classics
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• v.33 no.3
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• pp.21-36
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• 2020

Objectives : This paper aims to understand the meaning of '少陰人 心之範圍' and to determine its clinical implication. Methods : First, the meaning of the verb '範圍' was examined in 『IChing·XiCi(周易·繫辭傳)』 from where it originated. Based on the findings, the meaning of '心之範圍' in the context of the nature and emotion[性情] of So-eumin as explained in the 『DongUisusebowon(東醫壽世保元)』 was further investigated. Moreover, the clinical significance of the observation of '心之範圍' in relation to determining prognosis was discussed in regards to 'visceral syncope[藏厥]' and 'exuberating yin separating yang[陰盛隔陽]' which come under the severe symptoms[危證] category in the disease pattern of So-eumin. Results : '範圍' as mentioned in 『IChing·XiCi(周易·繫辭傳)』 refers to the process of creating a framework that takes after the tendencies of the patterns of change of the external world that influences mankind. The objective of this process is to prepare for the excessiveness and insufficiency of the change that happens in the external world so as to ultimately protect all existences. The workings of '範圍' could be assumed on a personal level as well. As the nature and emotion of So-eumin is closely related to the purpose and object of '範圍', Yi Jema suggested that through observing whether the So-eumin exhibits '心之範圍' or not, that it could be determined whether his/her innate nature is being properly exercised or not. Conclusions : Whether one's agitation calms down or not even for a moment is the criteria for determining prognosis of the entire disease, while its calming-down relies on proper functioning of '心之範圍'. The way to determine this is through observation of the manifest attitude of the So-eumin. If the So-eumin displays a poised and autonomous[綽綽卓卓] attitude even for a moment, it could be understood as the '心之範圍' process being properly functioning, indicating the overall direction to be heading towards relief of the sense of instability, allowing for a positive outlook on treatment.

• Journal of Korean Medical classics
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• v.29 no.3
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• pp.13-40
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• 2016

Objectives : The practice of bloodletting therapy has taken place for several millenia all over the world. The therapy is still one of the most popular oriental treatments in Korea. This paper studies bloodletting therapy in Huangdineijing to provide the Korean Medicine doctors with knowledge of the therapy to effectively utilize it in their clinics. Methods : The author studied all of the diseases treated by bloodletting therapy in Huangdineijing, and placed them into three categories: the visceral and bowel diseases, the meridian diseases, and miscellaneous diseases. The author reviewed reference documents that show clinical experiences of using the therapy and the results from the research on the therapy's therapeutic dynamics. Results : The treatment principals such as diagnostic methods, meridian points selection, acupuncture methods, and tools for the bloodletting therapy were provided. Most of the diseases treated by the therapy were identified by the visceral pattern identification or meridian pattern identification except miscellaneous diseases. The characteristics of the diseases treated by the therapy were studied and the diseases were placed into categories such as fever, pain, qi counterflow, first-aid, mental disease, and deep-seated disease. Theoretical basis of the mechanism of bloodletting therapy was drawn from several researches and a number of clinical theses related to bloodletting therapy. Conclusions : Results of this study on bloodletting therapy in Huangdineijing could be a useful knowledge for the Korean medicine doctors to be utilized their clinics. Future studies on this type of therapy should be performed to identify the diseases that may be effectively treated by bloodletting therapy.