• Journal of the Korea institute for structural maintenance and inspection
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• v.16 no.2
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• pp.40-48
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• 2012

Steel corrosion in concrete is a main cause of deterioration and early failure of concrete structures. A novel integration of electromagnetic heat induction and infrared (IR) thermography is proposed for nondestructive detection of steel corrosion in concrete, by taking advantage of the difference in thermal characteristics of corroded and non-corroded steel. This paper focuses on experimental investigation of the concept. An inductive heater is developed to remotely heat the embedded steel from concrete surface, which is integrated with an IR camera. Concrete samples with different cover depths are prepared. Each sample is embedded with a single rebar in the middle, resulting an identical cover depth from the front and the back surfaces, which enable heat induction from one surface and IR imaging from the other simultaneously. The impressed current (IC) method is adopted to induce accelerated corrosion on the rebar. IR video images are recorded during the entire heating and cooling periods. The test results demonstrate a clear difference in thermal characteristics between corroded and non-corroded samples. The corroded sample shows higher rates of heating and cooling than those of the non-corroded sample. This study demonstrates a potential for nondestructive detection of rebar corrosion in concrete.

• YAKHAK HOEJI
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• v.56 no.6
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• pp.377-381
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• 2012

The histidine-rich $Ca^{2+}$ binding protein (HRC) is a $Ca^{2+}$ binding protein in the sarcoplasmic reticulum (SR). In this study, we examined whether the HRC is involved in the regulation of cardiac contraction and $Ca^{2+}$ signaling using HRC knock-out (KO) mouse ventricular myocytes. In field-stimulated single mouse ventricular myocytes, cell shortenings and $Ca^{2+}$ transients were measured using a video edge detection and a confocal $Ca^{2+}$ imaging, respectively. Compared with the wide-type (WT) myocytes, the magnitudes of cell shortenings were significantly larger in HRC KO cells (P<0.01, WT vs. KO). The rate of contraction and relaxation was significantly accelerated in HRC KO myocytes (P<0.05 and P<0.01, respectively, WT vs. KO). The magnitudes of $Ca^{2+}$ transients were increased by HRC KO (P<0.01, WT vs. KO). In addition, the decay of the $Ca^{2+}$ transient was faster in HRC KO cells than in wild-type cells P<0.01, WT vs. KO). These results suggest that HRC may suppress SR $Ca^{2+}$ releases and decay of $Ca^{2+}$ transients during action potentials, thereby attenuating ventricular contraction and relaxation.

• Journal of the Korea Society of Computer and Information
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• v.18 no.8
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• pp.33-41
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• 2013

Intelligent automobile technology and IT convergence, the development of new imaging technology media applications based on open source Android installed on tracked, wheeled smart phone application technology and the development of intelligent vehicles as a new paradigm a lot of research and development being made. Android-based intelligent automotive applications, technology, and evolved into the center of a set of various multimedia technologies move beyond the limits of the means of each of multimedia platforms, services and applications that have been developed in such a distributed environment, has been developed according to a variety of services through technology mobile terminal device technology is an absolute requirement. In this paper, SVC Codec, real-time video and graphics processing and SoC design intelligent vehicles middleware applications with monolithic system specification through Android-based design of intelligent vehicles dedicated middleware research experiments on open platforms, and provides various terminal services functions SoC based on a newly designed and standardized interface analysis techniques in this study were verified through experiments.

• Journal of Korean Elementary Science Education
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• v.38 no.3
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• pp.406-425
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• 2019

The purpose of this study is to analyze The Effect of Teacher Participation-oriented Education Program (TPEP) centered on Multi-Faceted Analysis of Elementary Science Classes on the Class Expertise of novice teacher. First, in order to develop the TPEP, lectures and exploratory science classes were analyzed using imaging and eye-tracking techniques. In this study, the TPEP was developed in five stages: image analysis, eye analysis, teaching language analysis, gesture analysis, and class development. Participants directly analyzed the classes of experienced and novice teachers at each stage. The TPEP developed in this study is different from the existing teacher education program in that it reflected the human performance technology aspects. The participants analyzed actual elementary science classes in a multi-faceted way and developed better classes based on them. The results of this study are as follows. First, at the teacher training institutions and the school sites, pre-service teachers and novice teachers should be provided with various experiences in class analysis and multi-faceted analysis of their own classes. Second, through this study, we were able to identify the limitations of existing class observations and video analysis. Third, the TPEP should be developed to improve the novice teachers' class expertise. Finally, we hope that the results of this study are used as basic data in developing programs to improve teachers' class expertise in teacher training institutions and education policy institutions.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.25 no.10
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• pp.1310-1316
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• 2021

Recently, with the development of artificial intelligence and IoT technology, the importance of video processing such as object tracking, medical imaging, and object recognition is increasing. In particular, the noise reduction technology used in the preprocessing process demands the ability to effectively remove noise and maintain detailed features as the importance of system images increases. In this paper, we provide a modified weight filter based on pixel matching in an AWGN environment. The proposed algorithm uses a pixel matching method to maintain high-frequency components in which the pixel value of the image changes significantly, detects areas with highly relevant patterns in the peripheral area, and matches pixels required for output calculation. Classify the values. The final output is obtained by calculating the weight according to the similarity and spatial distance between the matching pixels with the center pixel in order to consider the edge component in the filtering process.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.32 no.3
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• pp.547-554
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• 2022

Recently, the field of telemedicine is growing rapidly due to the COVID-19 pandemic. However, the cost of telemedicine services is relatively high, since cloud computing, video conferencing, and cyber security should be considered. Therefore, in this paper, we design and implement a cost-effective P2P-based telemedicine system. It is implemented using the widely used the open source computing platform, Raspberry Pi, and P2P network that frees users from security problems such as the privacy leakage by the central server and DDoS attacks resulting from the server/client architecture and enables trustworthy identifying connection system using SSL protocol. Also it enables users to check the other party's status including body temperature in real time by installing a thermal imaging camera using Raspberry Pi. This allows several medical diagnoses that requires visual aids. The proposed telemedicine system will popularize telemedicine service and meet the ever-increasing demand for telemedicine.

• Korean Journal of Clinical Pharmacy
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• v.34 no.2
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• pp.134-139
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• 2024

Background: Increasing numbers of studies and research about artificial intelligence (AI) and machine learning (ML) have led to their application in clinical trials. The purpose of this study is to analyze computer-based new technologies (AI/ML) applied on clinical trials registered on ClinicalTrials.gov to elucidate current usage of these technologies. Methods: As of March 1st, 2023, protocols listed on ClinicalTrials.gov that claimed to use AI/ML and included at least one of the following interventions-Drug, Biological, Dietary Supplement, or Combination Product-were selected. The selected protocols were classified according to their context of use: 1) drug discovery; 2) toxicity prediction; 3) enrichment; 4) risk stratification/management; 5) dose selection/optimization; 6) adherence; 7) synthetic control; 8) endpoint assessment; 9) postmarketing surveillance; and 10) drug selection. Results: The applications of AI/ML were explored in 131 clinical trial protocols. The areas where AI/ML was most frequently utilized in clinical trials included endpoint assessment (n=80), followed by dose selection/optimization (n=15), risk stratification/management (n=13), drug discovery (n=4), adherence (n=4), drug selection (n=1) and enrichment (n=1). Conclusion: The most frequent application of AI/ML in clinical trials is in the fields of endpoint assessment, where the utilization is primarily focuses on the diagnosis of disease by imaging or video analyses. The number of clinical trials using artificial intelligence will increase as the technology continues to develop rapidly, making it necessary for regulatory associates to establish proper regulations for these clinical trials.

• The Korean Journal of Physiology and Pharmacology
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• v.28 no.4
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• pp.335-344
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• 2024

Diphenyleneiodonium (DPI) has been widely used as an inhibitor of NADPH oxidase (Nox) to discover its function in cardiac myocytes under various stimuli. However, the effects of DPI itself on Ca²⁺ signaling and contraction in cardiac myocytes under control conditions have not been understood. We investigated the effects of DPI on contraction and Ca²⁺ signaling and their underlying mechanisms using video edge detection, confocal imaging, and whole-cell patch clamp technique in isolated rat cardiac myocytes. Application of DPI suppressed cell shortenings in a concentration-dependent manner (IC₅₀ of ≅0.17 µM) with a maximal inhibition of ~70% at ~100 µM. DPI decreased the magnitude of Ca²⁺ transient and sarcoplasmic reticulum Ca²⁺ content by 20%-30% at 3 µM that is usually used to remove the Nox activity, with no effect on fractional release. There was no significant change in the half-decay time of Ca²⁺ transients by DPI. The L-type Ca²⁺ current (I_Ca) was decreased concentration-dependently by DPI (IC₅₀ of ≅40.3 µM) with ≅13.1%-inhibition at 3 µM. The frequency of Ca²⁺ sparks was reduced by 3 µM DPI (by ~25%), which was resistant to a brief removal of external Ca²⁺ and Na⁺. Mitochondrial superoxide level was reduced by DPI at 3-100 µM. Our data suggest that DPI may suppress L-type Ca²⁺ channel and RyR, thereby attenuating Ca²⁺-induced Ca²⁺ release and contractility in cardiac myocytes, and that such DPI effects may be related to mitochondrial metabolic suppression.

• Clinical Endoscopy
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• v.55 no.2
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• pp.270-278
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• 2022

Background/Aims: Endoscopic evaluation of intraductal papillary mucinous neoplasms (IPMNs) is useful in determining whether the lesions are benign or malignant. This study aimed to examine the usefulness of peroral pancreatoscopy (POPS) in determining the prognosis of IPMNs. Methods: POPS with videoscopy was performed using the mother-baby scope technique. After surgery, computed tomography/magnetic resonance cholangiopancreatography or ultrasonography and blood tests were performed every 6 months during the follow-up. Results: A total of 39 patients with main pancreatic duct (MPD)-type IPMNs underwent POPS using a videoscope, and the protrusions in the MPD were observed in 36 patients. The sensitivity and specificity of cytology/biopsy performed at the time of POPS were 85% and 87.5%, respectively. Of 19 patients who underwent surgery, 18 (95%) patients had negative surgical margins and 1 (5%) patient had a positive margin. Conclusions: In IPMNs with dilatation of the MPD, POPS is considered effective if the lesions can be directly observed. The diagnosis of benign and malignant lesions is possible depending on the degree of lesion elevation. However, in some cases, slightly elevated lesions may increase in size during the follow-up or multiple lesions may be simultaneously present; therefore, careful follow-up is necessary.

• Journal of radiological science and technology
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• v.32 no.2
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• pp.183-194
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• 2009

Purpose : This study was performed not only to compare the brain activation regions associated with sexual arousal induced by visual stimulation and SP6 acupuncture, but also to evaluate its differential neuro-anatomical mechanism in healthy women using functional magnetic resonance imaging (fMRI) at 3 Tesla (T). Subjects and methods : A total of 21 healthy right-handed female volunteers (mean age 22 years, range 19 to 32) underwent fMRI on a 3T MR scanner. The stimulation paradigm for sexual arousal consisted of two alternating periods of rest and activation. It began with a 1-minute rest period, 3 minutes of stimulation with either of an erotic video film or SP6 acupuncture, followed by 1-minute rest. In addition, a comparative study on the brain activation patterns between an acupoint and a shampoint nearby GB37 was performed. The fMRI data were obtained from 20 slices parallel to the AC-PC line on an axial plane, giving a total of 2,000 images. The mean activation maps were constructed and analyzed by using the statistical parametric mapping (SPM99) software. Results : As comparison with the shampoint, the acupoint showed 5 times and 2 times higher activities in the neocortex and limbic system, respectively. Note that brain activation in response to stimulation with the shampoint was not observed in the regions including the HTHL in the diencephalon, GLO and AMYG in the basal ganglia, and SMG in the parietal lobe. In the comparative study of visual stimulation vs. SP6 acupuncture, the mean activation ratio of stimulus was not significantly different to each other in both the neocortex and the limbic system (p < 0.05). The mean activities induced by both stimuli were not significantly different in the neocortex, whereas the acupunctural stimulation showed higher activity in the limbic system (p < 0.05). Conclusions : This study compared the differential brain activation patterns and the neural mechanisms for sexual arousal, which were induced by visual stimulation and SP6 acupuncture by using 3T fMRI. These findings will be useful to understand the theory of traditional acupuncture and acupoint channel in scientific point of view.