• Title/Summary/Keyword: via in pad

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Effect of Eriobotrya folium on Local Fat via Regulation of Lipase Secretion (비파엽추출물의 지방분해효소 조절을 통한 국소 지방분해 효능)

  • Lee, Woonkyeu;Choi, You Yeon;Yang, Woong Mo
    • Journal of Korean Medicine for Obesity Research
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    • v.17 no.2
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    • pp.101-110
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    • 2017
  • Objectives: In this study, the lipolytic effects of Eriobotrya folium extract (EFE) on local fat was investigated in high fat diet (HFD)-induced obesity mouse and 3T3-L1 adipocytes. Methods: C57BL/6J mice (5 weeks) were fed HFD for 6 weeks to induce obesity. EFE (20 mg/ml, $100{\mu}l$) or saline ($100{\mu}l$) as a normal control was injected into left inguinal fat pad region, 3 times per a week for last 2 weeks. After sacrifice, body weight, and histological changes of the inguinal fat pad were evaluated. The expressions of hormone-sensitive lipase (HSL) and adipose triglyceride lipase (ATGL) in inguinal fat pad were analyzed by Western blotting. Also, lipid accumulation and lipases release were determined in 3T3-L1 adipocytes by oil red o staining. Results: EFE significantly reduced the weight of inguinal fat pad and the size of adipocytes in HFD-induced obesity mice compared to control. The treatment of EFE up-regulated the expressions of HSL and ATGL in inguinal fat pads of obesity mice, as well as 3T3-L1 adipocytes. In addition, EFE inhibited the lipid accumulation in 3T3-L1 adipocytes in a dose dependent manner. Conclusions: EFE showed lipolytic effect on local fat of HFD-induced obesity mice by up-regulation of the lipases secretion. This suggests that EFE could be considered as anti-obese substance with lipolytic property on local fat.

Optimum Stiffness of the Sleeper Pad on an Open-Deck Steel Railway Bridge using Flexible Multibody Dynamic Analysis (유연다물체동적해석을 이용한 무도상교량 침목패드의 최적 강성 산정)

  • Chae, Sooho;Kim, Minsu;Back, In-Chul;Choi, Sanghyun
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.35 no.2
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    • pp.131-140
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    • 2022
  • Installing Continuous Welded Rail (CWR) is one of the economical ways to resolve the challenges of noise, vibration, and the open-deck steel railway bridge impact, and the SSF method using the interlocking sleeper fastener has recently been developed. In this study, the method employed for determining the optimum vertical stiffness of the sleeper pad installed under the bridge sleeper, which is utilized to adjust the rail height and absorb shock when the train passes when the interlocking sleeper fastener is applied, is presented. To determine the optimal vertical stiffness of the sleeper pad, related existing design codes are reviewed, and, running safety, ride comfort, track safety, and bridge vibration according to the change in the vertical stiffness of the sleeper pad are estimated via flexible multi-body dynamic analysis,. The flexible multi-body dynamic analysis is performed using commercial programs ABAQUS and VI-Rail. The numerical analysis is conducted using the bridge model for a 30m-long plate girder bridge, and the response is calculated when passing ITX Saemaeul and KTX vehicles and freight wagon when the vertical stiffness of the sleeper pad is altered from 7.5 kN/mm to 240 kN/mm. The optimum stiffness of the sleeper pad is calculated as 200 kN/mm under the conditions of the track components applied to the numerical analysis.

Influence of Smart Phone Food Delivery Apps' Service Quality on Emotional Response and App Reuse Intention - Focused on PAD Theory - (스마트 폰 배달 앱의 서비스품질이 감정반응과 앱 재이용의도에 미치는 영향 - PAD 이론을 중심으로 -)

  • Jeon, Hyeon-Mo;Kim, Min-Jung;Jeong, Hyun-Chul
    • Culinary science and hospitality research
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    • v.22 no.2
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    • pp.206-221
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    • 2016
  • This study presented the need to research into 'emotional response' and 'willingness to use apps', perceived by consumers using food delivery apps amidst the spread of smartphones and surge in use of food delivery apps. This study was also intended to present 'service quality' of food delivery apps, along with 'arousal' and 'pleasure' which represented the 2 types of emotional dimension of Pleasure-Arousal-Dominance(PAD), as variables that could strengthen the willingness to use food delivery apps and examine their roles. On the basis of results of such analysis, we intended to provide basic data necessary for development and operation of food delivery app contents. For subjects and spatial scope of this study, we selected domestic male and female residents nationwide who were aged 20 or older and had experience of using food delivery apps over the last 3 months. Among the subjects of this study, we surveyed foodservice consumers who had experienced of ordering food via food delivery apps such as Baedal Minjok, Yogiyo, and Baedaltong. Based on results of this study, it was found that design and sympathy related to food delivery app service quality had a positive effect on arousal while design and reliability had a positive effect on pleasure. Both informativity and mobility of food delivery app service quality were found to have a positive effect on the willingness to use apps. The pleasure from PAD had a positive effect on willingness to use apps, while arousal did not have any effect on willingness to use apps. The results of this study suggested that design and reliability, informativity, mobility were very important factors in inducing foodservice consumers to use food delivery apps continuously.

Study on the Durability of Composite Tilting Pad Journal Bearing for Turbo Compressor System under Oil-cut Situation (터보 컴프레셔용 복합재료 틸팅 패드 저널 베어링의 오일 공급 중단 상황에서의 내구성 연구)

  • Choe, Kang-Yeong;Jung, Min-Hye;You, Jun-Il;Song, Seung-A;Kim, Seong-Su
    • Composites Research
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    • v.29 no.3
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    • pp.111-116
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    • 2016
  • The tilting pad journal bearing for the turbo compressor application has a role to support high speed and heavy loading rotor. White metal has been widely used for the bearing material but the conventional bearing is immediately suspended and induces serious serious damage to the rotor under the unexpected oil cut situation or the insufficient oil film formation. The carbon fiber reinforced composite having high specific stiffness, specific strength and excellent tribological characteristics can solve these seizure problems. In this work, the study on the durability of high thermal resistance carbon fiber/epoxy composite tilting pad journal bearing under oil cut situation was conducted. The material properties of the composite materials including tensile, compressive and interlaminar properties were measured at room and high temperature of oil cut situation. To investigate the possibility of failure of composite tilting pad journal bearing under oil cut situation, the stress distribution of the composite bearing was analyzed via finite element analysis and the Tsai-Wu Failure index was calculated. To verify the failure analysis results, the oil cut tests for the composite tilting pad journal bearing were conducted using industrial test bench.

Glow Discharge as Detector for Gas Chromatography (글로우방전을 이용한 가스크로마토그라프 검출기의 개발)

  • 김효진;박일영;장성기;김박광;박만기
    • YAKHAK HOEJI
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    • v.37 no.1
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    • pp.76-83
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    • 1993
  • The changes in discharge current, emission and/or oscillation frequency of the electric oscillation of a glow discharge are the potential sensitive measure of the concentration of an impurity in the argon plasma supporting gas. A single jet enhanced glow discharge has been interfaced with the gas chromatograph via 1/8" O.D. tube with a heating pad to study the changes in discharge current. To investigate the optimum operating conditions of the glow discharge system as detector for gas chromatography, pressure, gas flow rate, discharge current, distance between the anode and the cathode have been studied.

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Estrogen Attenuates the Pressor Response Mediated by the Group III Mechanoreflex (폐경전후 여성의 Group III 기계적 수용기 자극 시 운동승압반사의 비교)

  • Park, Seung-Ae;Kim, Jong-Kyung
    • Journal of Korean Academy of Nursing
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    • v.41 no.2
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    • pp.191-196
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    • 2011
  • Purpose: We investigated the effects of group III mechanoreceptors to cardiovascular responses in both pre-menopausal woman and post-menopausal woman during passive ankle dorsiflexion (PAD). Methods: Twenty healthy volunteers (10 post-menopausal women and 10 pre-menopausal women) were recruited for this study. Stroke volume (SV), heart rate (HR), cardiac output (CO), and total vascular conductances (TVC) were measured continuously throughout the experiment. To stimulate the group III mechanoreceptors, PAD was performed for one minute. Results: The results showed that mean arterial pressure (MAP) mediated by the mechanoreflex activation was significantly increased in both groups. However, this pressor response was significantly higher in post-menopausal women. This reflex significantly increased both SV and CO in pre-menopausal women, while there were no differences in post-menopausal women. There was no difference in HR in either group. The mechanoreflex significantly decreased TVC in post-menopausal woman, while there was no difference in pre-menopausal woman. Conclusion: The results indicate that the excessive pressor response mediated by the mechanoreflex occurs due to overactivity of group III mechanorecptors and the mechanism is produced mainly via peripheral vasoconstriction in post-menopausal women.

The Effect of Ephedra sinica Pharmacopuncture on Lipid Metabolism in an Experimental Mouse Model of Obesity (마황약침(麻黃藥鍼)이 비만 유발 생쥐의 지방대사에 미치는 영향)

  • Kim, Hyo-jae;Kim, Eun-ji;Han, Yang-hee
    • The Journal of Internal Korean Medicine
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    • v.37 no.4
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    • pp.579-590
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    • 2016
  • Objectives: This study aimed to investigate the impact of Ephedra sinica pharmacopuncture on the weight and lipid metabolism of obese mice.Methods: Obesity was induced in male C57BL/6 mice by a 60% fat diet. The animals were divided into three groups (n=5) fed a normal diet, high-fat diet, and high-fat diet with Ephedra sinica pharmacopuncture. After 13 wk, fasting blood sugar levels were measured in each group, and oral glucose tolerance tests were conducted. After 15 wk, body weight, epididymal fat pad weight, subcutaneous fat pad weight, and serum lipid and gene expression of hormone sensitive lipase (HSL), adipose triglyceride lipase (ATGL), monoacylglycerol lipase (MGL), perilipin, and peroxisome proliferator-activated receptor (PPAR)-γ were measured in each group.Results: In the Ephedra group, body weight, fasting blood sugar, and oral glucose tolerance were significantly decreased. In addition, in the Ephedra group, the gene expression of HSL was significantly increased, whereas that of perilipin was significantly decreased.Conclusions: These results provide evidence that E. sinicapharmacopuncture affects obesity and obesity-induced metabolic syndrome, including insulin resistance and dyslipidemia, by activating lipolysis via the HSL pathway in adipose tissue.

Lateral arthroplasty along with buccal fat pad inter-positioning in the management of Sawhney type III temporomandibular joint ankylosis

  • Malhotra, Vijay Laxmy;Singh, Virendra;Rao, JK Dayashankara;Yadav, Sunil;Gupta, Pranav;Shyam, Radhey;Kirti, Shruti
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.45 no.3
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    • pp.129-134
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    • 2019
  • Objectives: The objective of this study was to highlight the role of lateral arthroplasty along with interposition of the buccal fat pad (BFP) in the management of Sawhney type III temporomandibular joint (TMJ) ankylosis. Materials and Methods: Ten patients with TMJ ankylosis (7 unilateral and 3 bilateral, total of 13 joints) were treated with lateral arthroplasty and BFP interposition. The bony bridge of the ankylotic mass on the lateral aspect was resected, leaving a distance of 1.5 to 2.0 cm from the base of the skull to the neck of the condyle. The condyle was left intact. Coronoidectomy was performed on the ipsilateral side via the same approach in all cases. The inter-incisal opening was measured at that time, and if it was less than 35 mm, contralateral coronoidectomy was performed by using the intra-oral approach. After satisfactory inter-incisal mouth opening (${\geq}35mm$) was achieved, the TMJ surgical site was revisited, and BFP was retrieved and used to cover the lateral aspect of the medially placed condyle. Results: With lateral arthroplasty, the medially displaced condyle can be left in-situ to maintain the mandibular ramal height and function and to act as a growth center in children. Interposition of the BFP prevents reformation of the lateral bony bridge that was removed. Conclusion: Lateral arthroplasty along with interpositioning of the BFP is a novel technique for managing Sawhney type III ankylosis that achieves management goals while avoiding complex and advanced reconstructive surgical procedures.

Adsorption Behavior of PAHs in Cigarette Smoke on Glass Beads - Effect of Plasma Polymerization Coating (담배 연기 내 PAH의 유리입자에 대한 흡착거동 - 플라즈마 고분자 중합 코팅 영향)

  • Basarir, Fevzihan;Rhee, Moon-Soo;Lee, Young-Taek;Yoon, Tae-Ho
    • Journal of Adhesion and Interface
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    • v.11 no.4
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    • pp.137-143
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    • 2010
  • Glass beads (GBs) were modified via plasma polymerization coatings in order to enhance the adsorption of polycyclic aromatic hydrocarbons (PAHs) in cigarette smoke and activated carbons (ACs) were also utilized for comparative purposes. First, GBs and ACs were subjected to surface modification via plasma polymerization coating of acrylic acid, acrylonitrile, 1,3-diaminopropane, thiophene or dimethylphosphite with a RF plasma (13.56 MHz) generator. Next, their adsorption behavior was evaluated with a home-made 4-port smoking machine by collecting the total particulate matters (TPMs) on a Cambridge filter pad, followed by the separation of PAHs via solid phase extraction and analysis with GC/MS. Finally, the plasma polymerization coatings were analyzed by FT-IR/ATR to elucidate the adsorption mechanism, while the topology of the modified GBs and ACs were studied by FE-SEM.

EFFECT OF CIGARETTE PAPER ON CIGARETTEAPPEARANCE BURN RATE AND SIDESTREAM SMOKE

  • Jr Vladimir Hampl
    • Proceedings of the Korean Society of Tobacco Science Conference
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    • 2000.05a
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    • pp.12-21
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    • 2000
  • The smoke from a burning cigarette is classified as mainstream, which is the smoke inhaled by the smoker during a puff, and sidestream, which is defined by ISO 10185 as all smoke which leaves a cigarette during the smoking process other than from the butt end. Most of the sidestream smoke is generated during static burn, that is, in between puffs. The amount of sidestream smoke generated by a cigarette depends on the cigarette construction, tobacco blend, and properties of the cigarette paper, The main paper properties affecting sidestream smoke generation are: porosity, basis weight, type and amount of filler, type and amount of burn additive.Sidestream smoke is composed of a visible phase (small liquid droplets) and an invisible phase (gaseous molecules). This paper focuses on the visible portion of the sidestream smoke. Optical methods, which are based on the relationship between light scattering and density of the rising plume of smoke, have been used successfully by the industry. However, the present trend is to use gravimetric methods where the particulate matter is captured on a Cambridge(R) filter pad and weighed. The gaseous portion of the sidestream smoke, which does not contribute to the visible sidestream smoke, passes through the Cambridge filter pad.Sidestream smoke reduction is achieved by modifying certain mass transport processes occurring in a smoldering cigarette. There are four main pathways for reducing sidestream smoke: A) less tobacco burned, B) slower rate of tobacco combustion, C) more efficient trapping of smoke by the cigarette paper, and D) more complete combustion of tobacco. This paper discusses how the physical properties of paper and cigarette construction affect sidestream smoke reduction via the above four mechanisms.

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