• 대한수의학회지
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• 제63권3호
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• pp.26.1-26.5
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• 2023

Syringobulbia is a rare neurological disorder characterized by a fluid-filled cavity in the brainstem. In this study, clinical signs, features on magnetic resonance imaging (MRI), and the diseases present concurrently with syringobulbia were investigated in 33 small breed dogs. Most dogs (97%) had concurrent syringomyelia, and some dogs (24%) presented with vestibular or cranial nerve symptoms associated with the medulla oblongata. MRIs revealed slit-like, bulbous, and vertical linear shapes of the cavities on T2-weighted hyperintense and T1-weighted hypointense signals similar to the cerebrospinal fluid. Chiari-like malformations were identified in all dogs. This study highlights the association of syringobulbia with syringomyelia and Chiari-like malformations in small breed dogs with or without brainstem-associated clinical signs.

• 대한통합의학회지
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• 제8권3호
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• pp.133-142
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• 2020

Purpose : The purpose of this study was to investigate the differences in social quotient and sensory processing function between completed-toileting and incomplete-toileting children with autism spectrum disorder (ASD). We aims to provide a basis for the training of children with autism spectrum disorders. Methods : The subjects of this research were children with ASD, aged from 4 to 7, receiving sensory integration therapy at the H-Child Development Research Center in Busan, South Korea. After recruiting 30 parents who had children with ASD, we interviewed them and we divided their children into completed-toileting group and incomplete-toileting group based on the past researches. We assessed them using the Social Maturity Scale and Sensory Profile. Spearman correlation was used to analyze between the sensory processing score and social quotient. Mann-Whitney U test was used to compare the Sensory Profile scores of the two groups. Results : The social quotient was correlated with the sensory processing score in the most of component as for auditory processing, vestibular processing, touch processing, multisensory processing, orosensory processing, except for visual processing. The groups of completed-toileting and incomplete-toileting group showed statistically significant intergroup difference in sensory seeking, emotional reactive, oral-sensory sensitivity, and inattention/distractibility in the sensory factor region. No statistically significant difference from intergroup was observed in any modulation areas, nor in behavioral & emotional response domains. Conclusion : A significant intergroup difference was observed in the most of sensory processing areas, except for modulation areas and behavioral & emotional response domains. The result revealed that toileting is significantly correlated with sensory processing. Therefore, this study suggests that the sensory processing function should be considered in the toilet training of children with ASD.

• 대한감각통합치료학회지
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• 제11권2호
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• pp.1-11
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• 2013

목적 : 본 연구는 감각통합중재가 취학 전 자세조절장애 아동의 자세조절과 작업수행(놀이)에 미치는 영향을 알아보고자 하였다. 연구방법 : 대상은 2012년 대한감각통합치료학회 임상과정에 참여한 만 5세 8개월의 남아이다. 평가결과에 따라 치료목표, 치료계획을 제시하였고 11회기 동안 치료가 진행 되었으며 아동의 활동과 적응반응을 기술하였다. 각 회기별 목표를 목표성취척도(Goal Attainment Scale)를 이용해 측정하였으며 2012년 12월 재평가하였다. 결과 : 치료 후기 아동은 배와위굴곡자세를 20초 이상 유지하여 신체근위부 안정성이 향상되었고, 신체활동놀이 한 가지에 지속적으로 주의집중하여 노는 것이 향상되었다. 결론 : 본 연구를 통하여 고유-전정감각 중심의 감각통합 중재가 취학 전 자세조절장애 아동의 자세조절 향상과 함께 작업수행('신체활동놀이')에도 긍정적인 영향을 미치는 것을 알 수 있었다.

• Archives of Plastic Surgery
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• 제48권3호
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• pp.278-281
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• 2021

Facial palsy (FP) is a functional disorder of the facial nerve involving paralysis of the mimic muscles. According to the principle "time is muscle," early surgical treatment is tremendously important for preserving the mimic musculature if there are no signs of nerve function recovery. In a 49-year-old female patient, even 19 months after onset of FP, successful neurotization was still possible by a V-to-VII nerve transfer and cross-face nerve grafting. Our patient suffered from complete FP after vestibular schwannoma surgery. With continuous application of electrostimulation (ES) therapy, the patient was able to bridge the period between the first onset of FP and neurotization surgery. The significance of ES for mimic musculature preservation in FP patients has not yet been fully clarified. More attention should be paid to this form of therapy in order to preserve the facial musculature, and its benefits should be evaluated in further prospective clinical studies.

• 대한감각통합치료학회지
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• 제21권3호
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• pp.54-64
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• 2023

목적 : 본 연구는 구강감각의 감각조절장애가 있는 발달지연 아동을 대상으로 구강활동을 포함한 감각통합 치료를 적용하여 침 흘림과 구강장난감을 활용한 놀이에 대한 효과를 알아보고자 하였다. 연구방법 : 연구대상은 2세 8개월의 구강감각의 감각조절장애가 있는 발달지연 남아 2명이었다. 단일대상연구 ABA' 중 대상자간 중다기초설계(multiple-baseline design across subjects)를 사용하였다. 목표행동은 목표성취도 척도(Goal Attainment Scale; GAS)를 사용하여 침 흘림과 구강 장난감을 활용한 놀이 대한 관심과 집중으로 측정하였다. 중재기(B) 10회기 동안 구강활동과 고유-전정 중심의 감각통합치료를 아동에게 적용하였다. 결과 : 침 흘림은 기초선 기간에 평균 목표행동 값(GAS)이 A 아동 0.25점, B 아동-0.5점에서 중재 기간에는 A 아동 1.88점, B 아동 1.4점으로 향상했고 유지기 동안 평균은 A, B 아동 모두 3점이었다. 놀이에 대한 기초선 기간에 평균 목표행동 값은 A 아동은 -0.75점, B 아동은 0.75점에서 중재 기간 A 아동은 1.9점, B 아동은 1.1점이었고 유지기 동안 평균은 A 아동 1.33점, B 아동 2점이었다. 결론 : 구강활동을 포함한 고유-전정감각 중심의 감각통합치료는 구강감각의 감각조절문제가 있는 아동에게 침 흘림과 구강장난감을 활용한 놀이에 효과가 있는 것으로 보인다.

• 대한후두음성언어의학회지
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• 제10권1호
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• pp.43-49
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• 1999

Objectives : The purpose of this study was to systematically analyze and compare e acoustic sound structure of vocal major student's singing voice. Materials and Methods : The nineteen vocal major students were the subject group and healthy nineteen females were the control group for this study. The subject group was taken a strobovideolaryngoscopy by the use of flexible nasopharyngoscopy. And acoustic analysis was taken between two groups. Additionally the inquiry on usual voice problems and management was performed by thirty-six vocal major students. Results : The subject group presents many functional voice disorder findings such as AP contraction(44%), phase difference(36%) tremor(25%), posterior gap(17%), hyperadduction of vestibular fold(6%), and anterior gap(3%) on strobovideolaryngoscopy. And the vocal major students did reveal an enhanced number of high frequency harmonic partials when singing compared to the control group in the narrow band spectrum study. But there was no significant difference in jitter, shimmer and noise to harmonic ratio in both groups. Almost all vocal major students present a lot of voice problems in singing such as loss of high note(17%), loss of quiet voice(17%), effortful and tired voice(36%) etc on inquiry. And they always effort to prevent vocal dysfunction by the use of various type of method such as voice rest(28%), hydration(28%), gargling with salt(11%) etc. Conclusions : The vocal major students always take care of maintaining a good voice condition, but a lot of vocal major students revealed abnormal strobovideolaryngoscopic findings and they are absent in the conception of systemic and scientific voice management. Therefore, the young singers need a good voice training and voice therapy Program under the good ralationship of laryngologist and voice training teacher.

• The Korean Journal of Physiology and Pharmacology
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• 제21권6호
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• pp.675-686
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• 2017

Orthostatic hypotension (OH) is associated with symptoms including headache, dizziness, and syncope. The incidence of OH increases with age. Attenuation of the vestibulosympathetic reflex (VSR) is also associated with an increased incidence of OH. In order to understand the pathophysiology of OH, we investigated the physiological characteristics of the VSR in the disorder. We applied sodium nitroprusside (SNP) to conscious rats with sinoaortic denervation in order to induce hypotension. Expression of pERK in the intermediolateral cell column (IMC) of the T4~7 thoracic spinal regions, blood epinephrine levels, and blood pressure were evaluated following the administration of glutamate and/or SNP. SNP-induced hypotension led to increased pERK expression in the medial vestibular nucleus (MVN), rostral ventrolateral medullary nucleus (RVLM) and the IMC, as well as increased blood epinephrine levels. We co-administered either a glutamate receptor agonist or a glutamate receptor antagonist to the MVN or the RVLM. The administration of the glutamate receptor agonists, AMPA or NMDA, to the MVN or RVLM led to elevated blood pressure, increased pERK expression in the IMC, and increased blood epinephrine levels. Administration of the glutamate receptor antagonists, CNQX or MK801, to the MVN or RVLM attenuated the increased pERK expression and blood epinephrine levels caused by SNP-induced hypotension. These results suggest that two components of the pathway which maintains blood pressure are involved in the VSR induced by SNP. These are the neurogenic control of blood pressure via the RVLM and the humoral control of blood pressure via epinephrine release from the adrenal medulla.

• Research in Vestibular Science
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• 제17권4호
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• pp.152-159
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• 2018

Objectives: The Korean Dizziness Handicap Inventory (KDHI), which includes 25 patient-reported items, has been used to assess self-reported dizziness in Korean patients with Parkinson disease (PD). Nevertheless, few studies have examined the KDHI based on item-response theory within this population. The aim of our study was to address the feasibility and clinimetric properties of the KDHI instrument using polytomous Rasch measurement analysis. Methods: The unidimensionality, scale targeting, separation reliability, item difficulty (severity), and response category utility of the KDHI were statistically assessed based on the Andrich rating scale model. The utilities of the orderedresponse categories of the 3-point Likert scale were analyzed with reference to the probability curves of the response categories. The separation reliability of the KDHI was assessed based on person separation reliability (PSR), which is used to measure the capacity to discriminate among groups of patients with different levels of balance deficits. Results: Principal component analyses of residuals revealed that the KDHI had unidimensionality. The KHDI had satisfactory PSR and there were no disordered thresholds in the 3-point rating scale. However, the KDHI showed several issues for inappropriate scale targeting and misfit items (items 1 and 2) for Rasch model. Conclusions: The KDHI provide unidimensional measures of imbalance symptoms in patients with PD with adequate separation reliability. There was no statistical evidence of disorder in polytomous rating scales. The Rasch analysis results suggest that the KDHI is a reliable scale for measuring the imbalance symptoms in PD patients, and identified parts for possible amendments in order to further improve the linear metric scale.