• Journal of the Korean Statistical Society
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• 제33권4호
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• pp.381-399
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• 2004

Statistical process control (SPC) and engineering process control (EPC) are based on different strategies for process quality improvement. SPC re-duces process variability by detecting and eliminating special causes of process variation, while EPC reduces process variability by adjusting compensatory variables to keep the quality variable close to target. Recently there has been need for an integrated process control (IPC) procedure which combines the two strategies. This paper considers a scheme that simultaneously applies SPC and EPC techniques to reduce the variation of a process. The process model under consideration is an IMA(1,1) model with a step shift. The EPC part of the scheme adjusts the process, while the SPC part of the scheme detects the occurrence of a special cause. For adjusting the process repeated adjustment is applied according to the predicted deviation from target. For detecting special causes the exponentially weighted moving average control chart is applied to the observed deviations. It was assumed that the adjustment under the presence of a special cause may increase the process variability or change the system gain. Reasonable choices of parameters for the IPC procedure are considered in the context of the mean squared deviation as well as the average run length.

• Annals of Clinical Neurophysiology
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• 제16권2호
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• pp.49-54
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• 2014

Heart rate variability is significantly associated with cardiovascular complications in various neurological disorders with cardiac impairment. Measures of spontaneous heart rate variability might be different from provocating tests of heart rate variability such as deep breathing and Valsava maneuver. Methods for analysis are divided into time domain methods and frequency domain methods. There are standard deviation of NN interval, standard deviation of average NN interval, root mean square of the successive differences, NN50, and pNN50 in time domain methods. Frequency domain bands can be divided into very low, low, and high frequency. Each variables are influenced by sympathetic and/or parasympathetic activity.

• 한국운동역학회지
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• 제17권1호
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• pp.129-134
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• 2007

The purpose of this study was to determine the variability of components of the vertical ground reaction force signal to seek the suitable number of attempt datum to be analyzed during running at 2m/s and 4m/s. For this study, six subjects (height mean:$174.5{\pm}4.4cm$, weight $671.5{\pm}116.4N.$, age:$25.0{\pm}yrs.$) were selected and asked to run at least 3 times each run condition randomly. FFT(fast Fourier transform) was used to analyze the frequency domain analysis of the vertical ground reaction forces signal and an accumulated PSD (power spectrum density) was calculated to reconstruct the certain signal. To examine the deviation of the vertical ground reaction between signals collected from an different number of attempt, variability of frequency, magnitude of passive peak, time up to the passive peak and maximum load rate were determined in a coefficient of variance. The variability analysis revealed that when analyze the vertical reaction force components at 2m/s speed running, which belongs to slow pace relatively, it would be good to calculate these components from signal of one attempt, but 4m/s speed running needs data collected from two attempts to decrease the deviation of signal between attempts. In summary, when analyzing the frequency and passive peak of the vertical reaction force signal during the fast run, it should be considered the number of attempt.

• 한국임상약학회지
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• 제30권1호
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• pp.36-43
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• 2020

Background: Tacrolimus, a calcineurin inhibitor, is an immunosuppressant used in post-transplantation maintenance therapy. The drug has a narrow therapeutic range and requires periodic therapeutic drug monitoring. Although many studies have reported the effects of intrapatient variability of tacrolimus on survival, rejection, and complications in renal transplant recipients, very few studies have reported these effects in liver transplant recipients. The purpose of this study was to evaluate the effect of intrapatient variability of tacrolimus on clinical outcomes after liver transplantation. Methods: Intrapatient variability was calculated using individual, averaged tacrolimus concentrations. Patients were divided into two groups according to their median variability value: high-variability and low-variability groups. The rate of deviation from the therapeutic range, incidence of acute rejection, post-transplant diabetes, incidence of infection, and estimated glomerular filtration rate (eGFR) after transplantation were compared between the groups. Results: Of the total patients (n=82), the high-variability group (n=41) exhibited significantly greater deviation from the therapeutic range (65.92% vs. 56.84%; p<0.001). There was no significant difference in acute rejection or post-transplantation diabetes incidence or eGFR; however, the number of infection in the first 6 months was significantly lower in the low-variability group (0.4 vs. 0.9 times; p=0.039). Multiple linear regression analysis showed that the number of infection significantly increased as intrapatient variability increased (p=0.015). Conclusion: High intrapatient variability in tacrolimus concentrations was strongly associated with an increased frequency of deviation from the suggested therapeutic range and an increased number of infection.

• 복식문화연구
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• 제23권4호
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• pp.604-615
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• 2015

The objectives of this study were to investigate whether heel height changes in the U.S. market occur in a cyclical pattern and heel heights show greater within-year variability over time. Heel height data from U.S. Vogue's spring and fall editions were analyzed over the time period 1950~2014. A total of 1581 pieces of data were measured in millimeter units using Adobe Illustrator and standardized by dividing the height of the heel by the shoe length through the curved sole line. To analyze the cycle pattern of heel heights, the yearly averages were standardized by using three-year moving average technique to average out the irregular components of time series data and give a better indication of the long-term fluctuation of heel height. To identify the degree of within-year variability of heel height, the standard deviation of the average measurements for a year was calculated, and then decade averages were drawn from the yearly averaged standard deviation. One-way ANOVA was conducted to compare the within-year variability of data in heel height over the time period studied by decade. The results showed: First, there was a trend toward higher heels from the early 1950s to 2011. Second, four cyclical movements of heel height were observed from 1950 to 2007, and heel heights gradually decreased after 2008. Third, the within-year variability significantly increased over time, especially after the 1980s.

• 한국지구물리탐사학회:학술대회논문집
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• 한국지구물리탐사학회 2003년도 Proceedings of the international symposium on the fusion technology
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• pp.192-197
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• 2003

It can be said that rock mass properties are characterized not by a mean value but by values with variation due to its characteristic uncertainty. This characteristic is one of the most important parts for the design of underground structures, but yet to be fully examined. Stochastic finite element method (SFEM) has been developed in order to take the randomness of structural systems into account. Using SFEM, the response variability of structural system can be obtained and it leads probabilistic stability of structure to be analyzed. In this study, displacements response variability of circular opening with hydrostatic stress field are analyzed in terms of rock mass properties having a certain mean and a standard deviation using the SFEM. The analyzed response variability shows that the necessity of probabilistic stability analysis of underground structures using reliable mean value and standard deviation of deformation modulus.

• 한국전기전자재료학회논문지
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• 제24권7호
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• pp.605-608
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• 2011

In this study, OSA (the obstructive sleep apnea) periods were detected in patients with OSA during sleep because of the treatment was different according to the frequency and symptoms of obstructive sleep apnea. ANS (autonomic nervous activity) was changed by obstructive sleep apnea periods so we intended to detect the periods to care the obstructive sleep apnea patients. RR intervals, SDNN (standard deviation of normal to normal) and RMSSD (root mean square standard deviation) were calculated in time domain analysis and LF (low frequency), HF (high frequency), NHF (normalized high frequency), NLF (normalized low frequency) were calculated in frequency domain analysis of HRV (heart rate variability) with obstructive sleep apnea patients. In this paper, SDNN (standard deviation of normal to normal) of time domain analysis were decreased in the obstructive sleep apnea periods. And NLF and LF/HF ratio were increased and NHF (normalized high frequency) was decreased in the frequency domain analysis. The parameters can be used to treat obstructive sleep apnea patients by detecting the obstructive sleep apnea periods such as CPAP (continuous positive airway pressure).

• 대한간호학회지
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• 제41권6호
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• pp.788-794
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• 2011

Purpose: Reduced heart rate variability significantly increases cardiovascular mortality. Metabolic syndrome increases the cardiac autonomic dysfunction. Recently, increasing cardiovascular mortality has been reported in patients with schizophrenia. This study was done to compare heart rate variability between adults with and without schizophrenia and to compare the relationship of heart rate variability to metabolic syndrome in hospitalized patients with schizophrenia. Methods: This was a descriptive and correlational study in which 719 adults without schizophrenia and 308 adults with schizophrenia took part between May and June 2008. We measured the following: five-minute heart rate variability; high-frequency, low-frequency, the ratio of low-frequency to high-frequency, and the Standard Deviation of all the normal RR intervals. Data was also collected on metabolic syndrome, abdominal obesity, triglycerides, HDL cholesterol, blood pressure and fasting glucose. Results: The Standard Deviation of all the normal RR intervals values of heart rate variability indices were $1.53{\pm}0.18$. The low-frequency and high-frequency values of heart rate variability indices were significantly higher in hospitalized patients with schizophrenia ($3.89{\pm}1.36$; $3.80{\pm}1.20$) than those in the healthy participants ($2.20{\pm}0.46$; $2.10{\pm}0.46$). There were no significant differences between the schizophrenic patients with and without metabolic syndrome. Conclusion: The results of this study indicate that schizophrenia patients have significantly lower cardiac autonomic control, but they have significantly higher low-frequency and high-frequency values than those of healthy adults. Use of antipsychotic drug may affect the autonomic nervous system in schizophrenic patients. Metabolic syndrome was not associated with cardiac autonomic control in schizophrenia patients.

• 대한한방부인과학회지
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• 제30권3호
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• pp.54-64
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• 2017

Objectives: The purpose of this study is to demonstrate Heart Rate Variability characteristics of menopausal patients with insomnia. Methods: From March 1, 2014 to June 20, 2017, Heart Rate Variability was measured in 102 menopausal patients who visited Cheonan Korean Medicine Hospital of Daejeon University. We compared accompanying symptoms and Heart Rate Variability values depending on sleep quality in menopausal women. Results: The accompanying symptoms of menopausal patients were as follows: hot flushes (45.1%), tiredness (25.49%), chest discomfort and palpitations (23.53%), headache (17.65%), arthralgia and muscular pain (17.65%), cold sensitivity of hands and feet (15.69%), urinary frequency (14.71%) and anxiety (10.78%). The frequency of chest discomfort and palpitation was significantly higher in the menopausal insomnia group than in normal sleep group. Comparing Heart Rate Variability between two groups, Standard deviation of the NN interval (SDNN), Total Power (TP), and Low Frequency (LF) values were significantly lower in insomnia group. Conclusions: Chest discomfort and palpitations were more frequent in insomnia patients in menopausal women than normal sleep group, and Standard deviation of the NN interval (SDNN), Total Power (TP), Low Frequency (LF) were significantly lower in HRV values.

• The Journal of Korean Physical Therapy
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• 제29권6호
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• pp.303-306
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• 2017

Purpose: Gait variability is defined as the intrinsic fluctuations which occur during continuous gait cycles. Increased gait variability is closely associated with increased fall risk in older adults. This study investigated the influence of attention-demanding tasks on gait variability in elderly healthy adults. Methods: We recruited 15 healthy elderly adults in this study. All participants performed two cognitive tasks: a subtraction dual-task (SDT) and working memory dual-task (WMDT) during gait plus one normal gait. Using the $LEGSys^+$ system, we measured the coefficient of variation (CV %=$100{\times}$[standard deviation/mean]) for participants' stride time, stride length, and stride velocity. Results: SDT gait showed significant increment of stride time variability compared with usual gait (p<0.05), however, stride length and velocity variability did not difference between SDT gait and usual gait (p>0.05). WMDT gait showed significant increment of stride time and velocity variability compared with usual gait (p<0.05). In addition, stride time variability during WMDT gait also significantly increased compared with SDT gait (p<0.05). Conclusion: We reported that SDT and WMDT gait can induce the increment of the gait variability in elderly adults. We assume that attention demanding task based on working memory has the most influence on the interference between cognitive and gait function. Understanding the changes during dual task gait in older ages would be helpful for physical intervention strategies and improved risk assessment.