• 제목/요약/키워드: vAm

검색결과 303건 처리시간 0.024초

Growth and characterization of detector-grade CdMnTeSe

  • J. Byun ;J. Seo;J. Seo ;B. Park
    • Nuclear Engineering and Technology
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    • 제54권11호
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    • pp.4215-4219
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    • 2022
  • The Cd0.95Mn0.05Te0.98Se0.02 (CMTS) ingot was grown by the vertical Bridgman technique at low pressure. All wafers showed high resistivity, which suggests potential as a room-temperature semiconductor detector. The resistivity of the CMTS planar detector was 1.47 × 1010 Ω·cm and mobility lifetime product of electrons was 1.29 × 10-3 cm2/V. The spectroscopic property with Am-241 and Co-57 was evaluated. The energy resolution about 59.5 keV gamma-ray of Am-241 was 11% and the photo-peak of 122 keV gamma-ray from Co-57 was clearly distinguished. The result shows the first detector-grade CMTS in the world and proves CMTS's potential as a radiation detector operating at room temperature.

폴리에틸렌 옥사이드가 암포테리신-B의 응집 특성 및 독성에 미치는 영향 (The Effect of Polyethylene Oxide on the Aggregation State and Toxicity of Amphotericin B)

  • 유봉규
    • Journal of Pharmaceutical Investigation
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    • 제31권1호
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    • pp.7-12
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    • 2001
  • Amphotericin B (AmB) is a drug of choice for the treatment of systemic fungal diseases, but its use is considerably limited due to a high incidence of toxicity, particularly nephrotoxicity. It has been demonstrated that the toxicity of AmB is caused by self-aggregated species of the drug and that unaggregated (monomeric) drug is nontoxic but still expresses antifungal activity. Poly (ethylene oxide) (PEO) is a water-soluble polymer, which may impact the aggregation state of AmB. We have studied the aggregation state of AmB as a function of PEO molecular weight and concentration. At 3,000 and 8,000 g/mole, there was minimal or no change of critical aggregation concentration (CAC) of AmB regardless of the concentration of polymer. By contrast at 20,000 g/mole, the CAC of AmB strikingly increased to 24.3 and $37.5\;{\mu}M$ at 5.0% and 10 % w/v of polymer, respectively. The critical overlap concentration (COC) of PEO 20,000 g/mole was 5.5%. It appears that an interaction between monomeric AmB and polymer coil increases above the COC, competing with self-aggregation of the drug. Accordingly, the degree of aggregation of AmB stayed low and the toxicity became less. There was no such effect at 3,000 and 8,000 g/mole of PEO, owing perhaps to small dimensions in comparison to AmB. Based upon these findings, less toxic AmB formulation may be developed by a pharmaceutical technique such as solid dispersion system containing both AmB and PEO 20,000 g/mole.

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Short Range Rear Obstacle Detector for Automobile Using 24GHz AM Radar Sensor

  • Kim, Young Su;Choi, Yun Ho;Han, Soo Deog;Bien, Franklin
    • 대한임베디드공학회논문지
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    • 제6권5호
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    • pp.281-286
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    • 2011
  • FMCW Radar sensor is commonly used for an automobile collision avoidance system for rider's safe. Systems using FMCW radar, however, would be one of expensive solutions for just simple rear obstacle detection purpose due to its high cost. In this letter, a short range rear obstacle detector using novel 24GHz AM radar sensor is presented. It can be implemented at significantly lower cost than FMCW radar for practical commercialization. The proposed AM radar sensor module is fabricated in a single aluminum housing to reduce the overall size while using single power supply voltage of 12V with 1200mA current for automotive applications. The measured detection range is up to 210cm with 10cm of distance resolution, which is suitable for a parking assistance system for automobiles.

Ti-6Al-4V의 AM에서 기계적 성질에 미치는 Interpass Peening의 영향 (The Effect of Interpass Peening on Mechanical Properties in Additive Manufacturing of Ti-6Al-4V)

  • 변재규;이희준;조상명
    • Journal of Welding and Joining
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    • 제35권2호
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    • pp.6-12
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    • 2017
  • Ti-alloys have high specific strength and are widely used for the filed of space aeronautics plant. However, it is difficult to process Ti-Alloys due to its high yield strength and it cannot raise the machining speed because it has a possibility of catching fire while processing. In order to reduce the number of processes for the Ti-alloys, the researches related to Additive Manufacturing(AM) have been actively carried out at the moment. As for the initial stage of AM market related to Ti-alloys, it started to use the raw material of powder metal, and it is currently being developed based on welding. In this study, Interpass peening reduced the size of the primary ${\beta}$ grain in the z-axis direction, increased the nucleation site of ${\alpha}-colony$, and decreased the length and width of ${\alpha}$ laths as though interpass rolling. Interpass peening leads to an increase in yield/ultimate tensile strength without decrease elongation, resulting decrease in anisotropy of the material.

K-SRI 에서의 방사성 중성자 선원교정 (Radioactive Neutron Source Calibration at the Korea Standards Research Institute)

  • 황선태;최길웅
    • Journal of Radiation Protection and Research
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    • 제10권1호
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    • pp.67-73
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    • 1985
  • 임의 중성자 선원의 중성자 방출율 측정과 경합핵종에 의한 중성자 포획, 열중성자 누출 및 선원자체의 중성자 흡수에 적용되는 보정을 포함하여 한국표준연구소에서의 중성자 선원교정을 위한 $MnSO_4$ 용액 방법을 기술한다. 본 보고서에서는 에너지가MeV 영역에서 사용되는 중성자 방사선 기기의 교정검사를 위하여 상용화되어 있는 중성자 선원 (Am-Be, $^{252}Cf$)을 고려하였다.

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Challenge to Future Displays: Transparent AM-OLED driven by PEALD grown ZnO TFT

  • Ko Park, Sang-Hee;Hwang, Chi-Sun;Byun, Chun-Won;Ryu, Min-Ki;Lee, Jeong-Ik;Chu, Hye-Yong;Cho, Kyoung-Ik;Chae, Jang-Youl;Han, Se-Jin
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2007년도 7th International Meeting on Information Display 제7권2호
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    • pp.1249-1252
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    • 2007
  • We have fabricated 3.5” transparent AM-OLED panel driven by PEALD grown ZnO TFT. The performance of ZnO thin film transistor was improved by adapting top gate structure, protection layer for ZnO from photolithography process, optimizing temperature and plasma power of ZnO growth process. The ZnO-TFT has a mobility of $8.9cm^2/V.s$, a subthreshold swing of 0.95V, and an on/off ratio of $10^7$.

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무선채널의 협대역화에 따른 변조방식 고찰 (A Survey on Modulation Methods for Narrow Bandwidth of Wireless Channel)

  • 박상영;이홍섭
    • 전자통신동향분석
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    • 제9권4호
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    • pp.131-138
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    • 1994
  • 최근 무선통신의 활성화에 따라, V/UHF(very/ultra high Frequency) 대역에서 한정된 주파수를 효율적으로 이용하기 위한 방법의 하나로서, 점차 점유 주파수 대역의 폭을 축소하여 보다 많은 이용자를 수용하도록 무선 채널의 협대역화가 추진되고 있다. 본 고에서는 먼저 V/UHF 대역 무선 통신에서 채널의 협대역화에 관련된 기술 중에서 현재까지 사용되고 있는 FM(frequency modulation), AM(amplitude modulation) 변조 방식의 장,단점을 살펴본후, 새로운 LM(linear modulation) 변조 방식에 대한 기술적 배경 및 특성을 알아보았다. LM은 SSR(single side band)-AM이 발전한 것으로서, TTIB(transparent tone-in-band), CLT(Cartesian loop transmitter), FFSR(feed-forward signal regeneration), DSP(digital signal processing)등 4가지의 기술이 결합하여 만들어진 것이다. LM 방식에 사용된 4가지 기술을 소개하고, 기존의 변조 방식에 비해 개선된 사항에 대해 서술한다.

Prosodic Boundary Effects on the V-to-V Lingual Movement in Korean

  • Cho, Tae-Hong;Yoon, Yeo-Min;Kim, Sa-Hyang
    • 말소리와 음성과학
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    • 제2권3호
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    • pp.101-113
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    • 2010
  • The present study investigated how the kinematics of the /a/-to-/i/ tongue movement in Korean would be influenced by prosodic boundary. The /a/-to-/i/ sequence was used as 'transboundary' test materials which occurred across a prosodic boundary as in /ilnjəʃ$^h$a/ # / minsakwae/ ('일년차#민사과에' 'the first year worker' # 'dept. of civil affairs'). It also tested whether the V-to-V tongue movement would be further influenced by its syllable structure with /m/ which was placed either in the coda condition (/am#i/) or in the onset condition (/a#mi). Results of an EMA (Electromagnetic Articulagraphy) study showed that kinematical parameters such as the movement distance (displacement), the movement duration, and the movement velocity (speed) all varied as a function of the boundary strength, showing an articulatory strengthening pattern of a "larger, longer and faster" movement. Interestingly, however, the larger, longer and faster pattern associated with boundary marking in Korean has often been observed with stress (prominence) marking in English. It was proposed that language-specific prosodic systems induce different ways in which phonetics and prosody interact: Korean, as a language without lexical stress and pitch accent, has more degree of freedom to express prosodic strengthening, while languages such as English have constraints, so that some strengthening patterns are reserved for lexical stress. The V-to-V tongue movement was also found to be influenced by the intervening consonant /m/'s syllable affiliation, showing a more preboundary lengthening of the tongue movement when /m/ was part of the preboundary syllable (/am#i/). The results, together, show that the fine-grained phonetic details do not simply arise as low-level physical phenomena, but reflect higher-level linguistic structures, such as syllable and prosodic structures. It was also discussed how the boundary-induced kinematic patterns could be accounted for in terms of the task dynamic model and the theory of the prosodic gesture ($\pi$-gesture).

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Amphotericin B의 가용화 및 방출지속화를 위한 아르기닌 함유 폴록사머 하이드로젤의 제조 및 특성분석 (Preparation and Characterization of L-Arginine Containing Poloxamer Hydrogels for Solubilization and Sustained Release of Amphotericin B)

  • 신백기;백은정;김예태;정지웅;노영창;임윤묵;박종석;허강무;박정숙
    • 폴리머
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    • 제34권5호
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    • pp.459-463
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    • 2010
  • 전신 진균감염 치료에 널리 사용되는 광범위 항진균제이며 대표적인 소수성 약물인 amphotericin B(AmB)의 효과적인 점막부착형 약물전달체로서 가용화제인 L-arginine, 점착성 고분자인 카보폴(carbopol), 온도감응성 고분자인 Poloxamer 407(P 407)로 구성된 하이드로젤 제형을 제조하였다. L-Arginine의 첨가로 AmB의 용해도가 2.6 mg/mL까지 향상되었으며, P 407 수용액은 20% w/v 이상의 농도에서 온도 변화에 따른 졸-젤-졸 상전이(phase transition)를 보였다. 이러한 상전이 온도는 약물 및 L-arginine의 존재에 의해 영향을 받았고, 점착성 고분자인 카보폴의 혼합에 의해 상전이 영역이 확장되었다. L-Arginine의 가용화 효과로 AmB의 약물방출특성이 향상되었고, 점착성 고분자인 카보폴의 첨가는 농도에 의존하여 약물방출을 지연시키는 효과가 있었다.

Polyamine류와 Imidazole 유도체가 배위된 Ni(Ⅱ) 착물의 저해 효과에 관한 분자궤도함수론적 해석 (Molecular Orbital Interpretation on the Inhibitory Effect of the Ni(Ⅱ) Complexes with Polyamines and Imidazole Derivatives)

  • 김정성;송영대
    • 대한화학회지
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    • 제48권2호
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    • pp.123-128
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    • 2004
  • 폴리아민과 이미다졸 유도체에 대해서 AM1, PM3, ZINDO/1법으로 형성엔탈피(${\Delta}H_f$), HOMO, LUMO에너지 및 쌍극자힘(${\mu}_D$) 값을 얻었다. 이들 리간드를 Ni(II)에 배위시킨 Ni(II)착물의 저해활성효과를 ZINDO/1(Zerner''s Intermediate Neglect of Differential Overlap No.1)법으로 조사하였다. Ni(II)착물의 중심금속의 알짜전하 값이 0.03 이상과 형성엔탈피가 음의 값으로 300 eV이상에서 실험적인 저해활성 값이 나타남을 보였다. 그 결과 Ni(II)착물은 불안정한 5배위 사각피라미드형인 [Ni(dpt)(tn)]$^{2+}$(dpt=3,3''-diaminodipropylamine)(tn=1,3-diaminopropane)와 일그러진 사면체인 [Ni(N-PropIm)$_2$(NCS))$_2$](N-PropIm=N-Propylimidazole)를 제외한 착물에서는 저해활성 값이 나타남을 알 수 있었다.