• Analytical Science and Technology
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• v.27 no.6
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• pp.284-291
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• 2014

The handling process of car indoor air quality is composed of 2 steps of testing. First, assambly part is tested to find a source of car indoor VOCs. Second, cut sample of unit component is tested to find a source material of VOCs emission. If the source material of VOCs emission is found, it can reduce car and assembly part of VOCs by improving material. As cut sample testing has problem of emission from cut surface to find the source of VOCs, it needs to apply unit components testing method. The aim of study is to evaluate VOCs impact factor of unit components in assembly parts. ISO 12219-5 test method reflects not only material effect but also surface area effect by testing unit component without cutting. The unit components of doortrim and console, were tested by ISO12219-5. And it could figure what unit component is main source of VOCs in assembly. And quantity conversion Factor which gets by testing assembly and unit components can be used to make guideline of ISO 12219-5.

• Proceedings of the SAREK Conference
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• 2006.06a
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• pp.1055-1060
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• 2006

The Korean Green Building Certification System was activated from 2005. The purpose of it is to improve the quality of residential unit. Recently, people stay inside of building more than for 90% of a day Accordingly, it is really important for them to make the quality of Indoor Environmental better, in brief, to develop the indoor environmental factor in KGBC is important. One of the best way to develop the system is to do research based on POE because the area of problem can be realized. Accordingly, we get the information about POE from another research for the part of the indoor environment for residential unit to have the critical mind about the KGBC, and tried to compare the factors to another which is from foreign Green Building Certification System such as LEED, BREEAM, GBTool, After they have been analyzed, we could find that some of factor need to be revised and added. Also, there was one problem that many part of factor was created without any consideration of direction of each space in residential unit.

• Nuclear Engineering and Technology
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• v.42 no.4
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• pp.394-413
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• 2010

The object of this paper is to identify the key elements that impact a radiation dose at EAB (Exclusion Area Boundary). This study is based on the AST (Alternative Source Terms) as defined in Regulatory Guide 1.183. The LOCA (Loss of Coolant Accident) and the LRA (Locked Rotor Accident) are selected as limiting cases. A sensitivity analysis of accidental behavior with respect to various parameters during LOCA and LRA at Kori Unit 1 is also undertaken for the following objectives: to determine the limiting parameters, to find the impact trend of the radiation dose, and to find the safety margin between AST and TID (Technical Information Document) methodologies. This work confirms that key parameters are particulate removal rate, decontamination factor, iodine chemical form, gap fraction, partitioning factor, and the impact of isotopes group. Comparing TID with AST, the radiation dose of TID is about 80% greater than that of AST under a LOCA, and about 60% greater than that of AST for the case of a LRA; thus the safety margin is remarkably increased when the AST is used. In this work, the sensitivity analysis results are presented in terms of a sensitivity index called the "NDD (Normalized Dose Difference)", which compares the impact of parameters with that of a reference case. These values are derived by using a combination of the leak rate (primary to secondary), iodine chemical form, gap fraction, partitioning factor, spray removal rate, source term, and other variables.

• Biotechnology and Bioprocess Engineering:BBE
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• v.5 no.2
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• pp.130-135
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• 2000

The characteristics of two different modes of perfusion culture, intermittent and continuous bleedings, were investigated by culturing the hybridoma cells producing von Willebrand Factor (vWF) monoclonal antibody (McAb) in a 15 L bioreactor without clogging the filter. Both culture methods exhibited similar profiles of cell density and metabolite concentrations during the culture period at the cell concentration of around 1${\times}$107 cells/mL. When the perfusion rate was increased, the intermittrnt bleeding culture showed problems of ammonia accumulation and decrease of cell viability. The continuous bleeding culture in terms of nutrient consumption and metabolite production kinetics. But the analysis of specific oxygen consumption rate showed that the specific oxygen consumption rate of intermittent bleeding culture was similar to that of exponential growth phase. The continuous bleeding culture showed higher specific oxygen consumption rate of intermittent bleeding culture. finally we proved the possibility of long-term operation of continuous bleeding culture and produced approximately 40 g of vWF McAb in a 15L bioreactor after one-month operation.

• The Korean Journal of Pain
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• v.35 no.3
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• pp.271-279
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• 2022

Background: Inflammation is known to underlie the pathogenesis in neuropathic pain. This study investigated the anti-inflammatory and neuroprotective mechanisms involved in antinociceptive effects of co-administration of acetaminophen and L-carnosine in chronic constriction injury (CCI)-induced peripheral neuropathy in male Wistar rats. Methods: Fifty-six male Wistar rats were randomly divided into seven experimental groups (n = 8) treated with normal saline/acetaminophen/acetaminophen + L-carnosine. CCI was used to induce neuropathic pain in rats. Hyperalgesia and allodynia were assessed using hotplate and von Frey tests, respectively. Investigation of spinal proinflammatory cytokines and antioxidant system were carried out after twenty-one days of treatment. Results: The results showed that the co-administration of acetaminophen and L-carnosine significantly (P < 0.001) increased the paw withdrawal threshold to thermal and mechanical stimuli in ligated rats compared to the ligated naïve group. There was a significant (P < 0.001) decrease in the levels of nuclear factor kappa light chain enhancer B cell inhibitor, calcium ion, interleukin-1-beta, and tumour necrotic factor-alpha in the spinal cord of the group coadministered with acetaminophen and L-carnosine compared to the ligated control group. Co-administration with acetaminophen and L-carnosine increased the antioxidant enzymatic activities and reduced the lipid peroxidation in the spinal cord. Conclusions: Co-administration of acetaminophen and L-carnosine has anti-inflammatory effects as a mechanism that mediate its antinociceptive effects in CCI-induced peripheral neuropathy in Wistar rat.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.23 no.3
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• pp.310-310
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• 2020

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2002.10a
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• pp.354-361
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• 2002

This paper propose section properties factor to generate stress history for fatigue analysis and safety inspection of steel bridge. A methodology is described for the computation of numerical stress histories in the steel truss bridge, caused by the vehicles using section properties factor. The global 3-D beam model of bridge is combined with the local shell model of selected details. Joint geometry is introduced by the local shell model. The global beam model takes the effects of joint rigidity and interaction of structural elements into account. Connection nodes in the global beam model correspond to the end cross-section centroids of the local shell model. Their displacements are interpreted as imposed deformations on the local shell model. The load cases fur the global model simulate the vertical unit force along the stringers. The load cases fer the local model are imposed unit deformations. Combining these, and applying vehicle loads, numerical stress histories are obtained. The method is illustrated by test load results of an existing bridge.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.18 no.36
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• pp.287-295
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• 1995

This paper is concerned with cost analysis model in periodic maintenance policy. Generally periodic maintenance policy in which item is repaired periodic interval times. And in the article minimal repair is considered. Mimimal repair means that if a unit fails, unit is instantaneously restored to same hazard rate curve as before failure. In the paper periodic maintenance policy with minimal repair is as follows; Operating unit is periodically replaced in periodic maintenance time, if a failure occurs between minimal repair and periodic maintenance time, unit is replaced by a new item until tile periodic maintenance time comes. Also unit undergoes minimal repair at failures in minimal-repair-for-failure interval. Then total expected cost per unit time is calculated according to scale parameter of failure distribution. Maintenance cost factors are included operating, fixed, minimal repair, periodic maintenance and new item replacement cost. Numerical example is shown in which failure time of system has weibull distribution.

• Proceeding of Spring/Autumn Annual Conference of KHA
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• 2006.11a
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• pp.202-207
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• 2006

This study was to find out users' satisfaction on the dormitory high school in Jeonju City and to propose it's physical environmental improvement directions. This was performed by a questionnaire survey method, and the questionnaire was designed by researchers considering relative literatures. Data were collected from 200 students, who had been dwelling 4 high school dormitories in Jeonju City. By analyzing those data, findings were as follows : 1) Users of students were satisfied the whole of their dormitory; facilities, spaces, and living. 2) They were highly concerned about a library and a personal unit space in their dormitory. 3) They needed their personal unit space to be designed bedroom+bathroom type with 2 persons' sharing and be equipped one story bed and desk furniture. Also, they needed improvement on heating & cooling, small space and indoor air quality of unit space. 4) The users' satisfaction on unit space were 3.23, and the space utility and the space size of functional factor and the heating/ventilation of technical factor were highly effected their satisfaction.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2008.11a
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• pp.604-605
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• 2008

Modal participation factor (MPF) is a widely used in a mode-coupling squeal noise problem for finding the most sensitive component over a complex brake system in a vehicle using eigenvectors of sub-components. This methodology requires the problematic total response of system by the unstable squeal noise at a specific frequency as well as eigenvectors of each component belonging to brake system. In this paper, a unit-force response analysis is performed for intact total system to obtain eigenvectors of each component and then such data is directly used for the contribution analysis of a squeal noise problem. Since the eigenvectors of each component induced from virtual unit-excitation is most reliable owing to the intact boundary condition, it can be expected that the corresponding contribution analysis with MPF also provides a trustworthy result.