• 한국생물정보학회:학술대회논문집
• /
• 한국생물정보시스템생물학회 2005년도 BIOINFO 2005
• /
• pp.109-112
• /
• 2005

Identifying orthologous paralogenes is a fundamental problem in comparative genomics and can facilitate the study of evolutionary history of the species. Existing approaches for locating paralogs make use of local alignment based algorithms such as BLAST. However, there are cases that genes with high alignment scores are not paralogenes. On the other hand, whole genome alignment tools are designed to locate orthologs. Most of these tools are based on some unique substrings (called anchors) in the corresponding orthologous pair to identify them. Intuitively, these tools may not be useful in identifying orthologous paralogenes as paralogenes are very similar and there may not be enough unique anchors. However, our study shows that this is not true. Paralogenes although are similar, they have undergone different mutations. So, there are enough unique anchors for identifying them. Our contributions include the followings. Based on this counter-intuitive finding, we propose to employ the whole genome alignment tools to help verifying paralogenes. Our experiments on five pairs of human-mouse chromosomes show that our approach is effective and can identify most of the mis-classified paralog groups (more than 80%). We verify our finding that whole genome alignment tools are able to locate orthologous paralogenes through a simulation study. The result from the study confirms our finding.

• 대한한의학원전학회지
• /
• 제27권3호
• /
• pp.11-31
• /
• 2014

Objectives : Nomenclature for medical terminology is the most important point in traditional medical standardization. For example, standard nomenclature for acupuncture points, herbal medicines and prescriptions have been treated. However, studies on standard nomenclature for traditional medical books are rare. Methods : Following up all articles in Journal of Korean Medical Classics[JKMC], which have romanized name for medical books and analyzing problems of those. Results : There were so several methods to write in romanized character even to unique and replaceable name. Conclusions : Romanized nomenclature for medical book as a terminology must have unique expression. So we suggest that authors to write articles have to use unique romanized nomenclature for medical books and books published in a certain country should be written in romanized characters with their own languages.

• 대한예방한의학회지
• /
• 제5권2호
• /
• pp.130-138
• /
• 2001

It is thought that Kim Hong-kyeong followed the existing theory of Meridian(經絡) and supplemented his unique perspectives in interpreting it. And he tried to relate Meridian with hygiene of mind. I took up with the research on the assumption that the review of Kim's method can present new perspectives to the study of relationship between Meridian and hygiene of mind. The results of my study are as follows: 1. Kim followed common theory of Meridian and then added his unique perspectives to it. His method of interpretation has one characteristic. By introducing Idealism(唯心論), he understood 'Meridian' as the path of the mind and the emotion. Especially I think his hypothesis that acupuncture can be widely used in mental diseases as well as body related diseases and its applications to treatment are very valuable. 2. Meridian and hygiene of mind are close together. I think Kim's unique trial is something new in studying relationship between Meridian and hygiene of mind but requires more research on it.

• 한국실내디자인학회논문집
• /
• 제19권5호
• /
• pp.48-55
• /
• 2010

Marcel Wanders, one of the greatest designers in the world of contemporary design, was born in the Netherlands. His works run the gamut from interior design to furniture design to lighting design, building a unique world of works. He started to gain fame when he presented "Knotted Chair" at Droog Design in 1996, which was made out of aramid ropes and later became his symbol. In 2000, he established "moooi," a world-renowned design label. By giving characteristic qualities, his works are given meaning, and like a fantastical dream, their images are extremely fantastical and stimulating. As can be seen in his character cover, he puts emphasis on the harmony between minimalism and decoration, establishing his own unique design concept. In this thesis, based on Marcel Wander's design philosophy, his overall design characteristics were classified into theatrical effects and storytelling. Expressive elements depaysement, eclectic mixture, and scale modification were derived from theatrical effects and analyzed; for storytelling, object, semantic cues, and dream and fantasy were derived and analyzed. A distinguishing feature of such analysis is his meaning-centric design approach, the principle by which to form long-term relationships with the users by creating user-centric designs that make them find meaning and values in diverse experiences in their daily routine, giving them familiar yet unique experience.

• 정보관리학회지
• /
• 제22권3호
• /
• pp.213-232
• /
• 2005

본 고의 목적은 초등학생용 독서자료의 텍스트수준에 영향을 미치는 요인들을 규명하여 텍스트수준 측정 공식을 구성함으로써 텍스트의 수준 평가를 자동화하는 데에 있다. 컴퓨터로 계량화할 수 있는 언어적 요인들을 대상으로 표본집단에 부여된 텍스트수준 점수와의 상관관계를 검토한 결과 글자수, 어절수, 이형어절수, 문장수, 단락수 요인이 텍스트수준을 결정하는 요인으로 드러났다. 단순회귀분석을 통해 도출된 회귀방정식들 중에서 이형어절수 모형이 최적의 공식으로 드러났으나, 중회귀분석을 한 결과 이형어절수요인과 새 어절출현비율요인을 결합한 모형은 설명력이 더욱 향상된 공식으로 밝혀졌다. 공식에 따라 측정된 텍스트수준 점수는 학년 내에서 매우 세분된 단계까지 나타내고 있으므로 각 학생별로 그들의 독서능력에 적합한 자료를 추천할 수 있다.

• Architectural research
• /
• 제2권1호
• /
• pp.1-6
• /
• 2000

Ever since Viollet-le-Due began to examine Gothic structural elements using his method of geometrical analysis in the nineteenth century, art and architectural historians and a few engineers have periodically attempted to ascertain the structural advantages of the various characteristic features of Gothic architecture. In none of these studies, however, has the way forces work within the lightweight and spacious masonry Gothic buildings been precisely interpreted. The approach taken by art and architectural historians has therefore tended to be primarily descriptive and to be based on intuitive assumptions. This study intend to analyze the Gothic non-vaulted nef unique(aisleless) structures of Lower Languedoc which has never been scientifically tested, and to provide as comprehensive an explanation as possible of the way in which these non-vaulted buildings work. In order to achieve this goal, this paper Is to examine, by means of finite element analysis. the links between the width of non-vaulted aisleless structures, the configuration of the arches, diaphragm arch, and the buttress. Finite element analysis with a computer provides a more accurate analysis than the methods of analysis that have been heretofore applied to Gothic structures, as well as permits us to visualize the global stress behavior of the structure. Combined with traditional methods of studying historical buildings, therefore, finite element analysis inevitably give us a broader understanding of the processes involved in the design and construction of medieval buildings.

• 대한수학회보
• /
• 제55권2호
• /
• pp.431-448
• /
• 2018

This paper is concerned with the positive definite solutions of the nonlinear matrix equation $X-A^*{\bar{X}}^{-1}A=Q$, where A, Q are given complex matrices with Q positive definite. We show that such a matrix equation always has a unique positive definite solution and if A is nonsingular, it also has a unique negative definite solution. Moreover, based on Sherman-Morrison-Woodbury formula, we derive elegant relationships between solutions of $X-A^*{\bar{X}}^{-1}A=I$ and the well-studied standard nonlinear matrix equation $Y+B^*Y^{-1}B=Q$, where B, Q are uniquely determined by A. Then several effective numerical algorithms for the unique positive definite solution of $X-A^*{\bar{X}}^{-1}A=Q$ with linear or quadratic convergence rate such as inverse-free fixed-point iteration, structure-preserving doubling algorithm, Newton algorithm are proposed. Numerical examples are presented to illustrate the effectiveness of all the theoretical results and the behavior of the considered algorithms.

• Bulletin of the Korean Chemical Society
• /
• 제35권3호
• /
• pp.845-850
• /
• 2014

The rapid development of shotgun proteomics is paving the way for extensive proteome profiling, while providing extensive information on various post translational modifications (PTMs) that occur to a proteome of interest. For example, the current phosphoproteomic methods can yield more than 10,000 phosphopeptides identified from a proteome sample. Despite these developments, it remains a challenging issue to pinpoint the true phosphorylation sites, especially when multiple sites are possible for phosphorylation in the peptides. We developed the Phospho-UMC filter, which is a simple method of localizing the site of phosphorylation using unique mass classes (UMCs) information to differentiate phosphopeptides with different phosphorylation sites and increase the confidence in phosphorylation site localization. The method was applied to large scale phosphopeptide profiling data and was demonstrated to be effective in the reducing ambiguity associated with the tandem mass spectrometric data analysis of phosphopeptides.

• 한국주거학회:학술대회논문집
• /
• 한국주거학회 2009년 춘계학술발표대회 논문집
• /
• pp.321-326
• /
• 2009

For building an urban image, various elements such as symbolic building, ethnic characteristics, historical background, natural environment, and diverse cultural elements can influence on it. Many cities in developed countries are showing their unique urban image reflecting their own culture, history, and aesthetic tastes. Especially color, one of the major design elements, has greater impact than other visual factors to form an urban characteristic. Despite the long history and cultural background, Seoul as a capital city of Korea does not show an unique city image with the perspective of color. Recently, Seoul has been designated as '2010 World Design Capital' and implements various urban design projects. As a leading city of design, Seoul is trying to make its urban identity through the own symbolic environment color. The purpose of this study is to find an environmental color scheme for developing a desirable urban design through several cases of foreign countries. For the purpose, Paris, London, Amsterdam, and Tokyo were selected as case cities. Each of the cities showed their own cultural characteristics and made their unique urban image by appropriate usage of their natural environment, symbolic building, emblem of country, and so on. We need to consider these successful cases to build up the image of Seoul.

• 복식
• /
• 제37권
• /
• pp.149-162
• /
• 1998

This study is thed Embroidery, Cross-stitchery, Weaving, Wax-Printing of technique and design appeared in textile of Miaos dwells in south-west among the minority people of china. The study is as follows. First, the technique of textile1) satin stitch, couching stitch, french-knot stitch, etc. using anther silk thread or cotton thread color 2) cross-stitchery 3) hand-weaving technique which is shaped other warp or weft using simple loom 4) the technique of dyeing of pattern using effect with wax. These methods are singly used mixing together, therefore doubled beauty. Second, these technuque of ornament have other independence, specially ornament apron, sling, sleeve borders, slack borderss, edge of upper garment, take off and put on easily, heighten effect of various ornament, can preserve many years. Third, Maker, female born in this country fashion by need of herself, used liberal method shown in unique creativity of life. This texture make standards capable female proud of intelligent and skill of herself. Fourth, Design appeared in textile like as pattern flying bird in the sky, strolling beast in the field, lion rolling gem, laughing dragon winding snake at gem, birks, flowers, fish, butterfly is used as the wish of long life, a lucky sign. They expressed creativity and unique conception using formation : the technique transform other shape using by omitting or adding or overestimating. Geometric pattern of tartan, revealing, Fifth, composition structure having balance and symmetry or contradiction towards center and circumstance of the center harmonized repeatedly method, expressed unique artful attraction by full composition.