• Title/Summary/Keyword: uncertain data

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Current Research Trend on the Acupuncture and Moxibustion Treatment for Pancreatitis (국내외 췌장염 관련 침구치료 연구 현황)

  • Kang, Ha Ra;Lee, Yeon Sun;Kim, Hye Ryeon;Kim, Eun Jung;Kim, Kyung Ho;Kim, Kap Sung;Jung, Chan Yung;Lee, Jun Kyu
    • Korean Journal of Acupuncture
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    • v.35 no.2
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    • pp.56-69
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    • 2018
  • Objectives : The aim of this study is to review the current research trend on the acupuncture and moxibustion treatment for pancreatitis. Methods : Through nine search engines, articles were collected, which had involved the use of acupuncture and moxibustion treatment for pancreatitis. Data were extracted from the selected articles regarding the year, country, type of pancreatitis, study design, evaluation variable, intervention, point for acupuncture and moxibustion, and effectiveness of treatment. Results : Total 56 articles were reviewed. The number of studies increased gradually every ten years. Fifty-one studies(91%) were conducted in China. Most of clinical studies and animal experimentations reported on acute pancreatitis. Thirty-nine studies were randomized controlled trials(RCTs), but most of them were assessed as uncertain in the risk of bias evaluation. The degree of overall improvement(79%) was used mainly as evaluation variable of clinical studies. In animal experimentations, the examination of pancreatitis tissue(77%) and blood test(77%) were used the most. Most of studies were conducted with the acupuncture, one with moxibustion. Among them, electroacupuncture was the most common intervention of treatment group. ST36 was the most frequently used acupuncture point in the included studies. Effective rate increased and serum amylase, clinical symptoms, recovery time of gastrointestinal function decreased statistically significantly in the treatment group of clinical studies. Conclusions : The result of this study could be used for the future practice and research about the acupuncture and moxibustion treatment for pancreatitis.

Clinical Applications of Chromosomal Microarray Analysis (염색체 Microarray 검사의 임상적 적용)

  • Seo, Eul-Ju
    • Journal of Genetic Medicine
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    • v.7 no.2
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    • pp.111-118
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    • 2010
  • Chromosomal microarray analysis (CMA) enables the genome-wide detection of submicroscopic chromosomal imbalances with greater precision and accuracy. In most other countries, CMA is now a commonly used clinical diagnostic test, replacing conventional cytogenetics or targeted detection such as FISH or PCR-based methods. Recently, some consensus statements have proposed utilization of CMA as a first-line test in patients with multiple congenital anomalies not specific to a well-delineated genetic syndrome, developmental delay/intellectual disability, or autism spectrum disorders. CMA can be used as an adjunct to conventional cytogenetics to identify chromosomal abnormalities observed in G-banding analysis in constitutional or acquired cases, leading to a more accurate and comprehensive assessment of chromosomal aberrations. Although CMA has distinct advantages, there are several limitations, including its inability to detect balanced chromosomal rearrangements and low-level mosaicism, its interpretation of copy number variants of uncertain clinical significance, and significantly higher costs. For these reasons, CMA is not currently a replacement for conventional cytogenetics in prenatal diagnosis. In clinical applications of CMA, knowledge and experience based on genetics and cytogenetics are required for data analysis and interpretation, and appropriate follow-up with genetic counseling is recommended.

The Study on the Parenting Experiences of Mothers with Borderline Intellectual Functioning Adolescents (경계선 지능 청소년 어머니의 양육경험에 관한 연구)

  • Kim, Go Eun;Kim, Hea Re
    • Korean Journal of Family Social Work
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    • no.61
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    • pp.137-168
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    • 2018
  • The purpose of this study was to understand deeply the experience and the meaning of mother's parenting experience on borderline intellectual functioning adolescents. The collected data through an in-depth interviews with six mothers were analyzed according to the Colaizzi's 7 procedures of analysis. This study found out 7 categories, 23 clusters of themes and 92 topics of borderline intellectual functioning adolescents parenting experience of mothers. 'On the borderline, live a life wandering off uncertain course', 'Watching precarious growth of child', 'Adolescence, reachead the limit', 'Being afraid of facing the future', 'A helpless condition', 'Pushing through struggles', 'Hoping the society where my child can live together' was found as the categories of experience of the research objects. With these findings, this study makes some recommendations and suggestions for the practice.

Optimization of Early-phase Ship Design using Set-Based Design and Genetic Algorithm (집합기반설계와 유전자알고리즘을 이용한 초기단계 함정설계 최적화)

  • Park, Jin-Won
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.10
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    • pp.486-492
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    • 2019
  • The system-based approach is needed to select an optimal mix of weapon systems and ship platform among a variety of design alternatives with the uncertainties of the initial required operational capability. In the early-phase design, which included a feasibility study and concept design, it is possible to cause problems when a review of the operational concept, database development, and systematic design are not done, thereby producing uncertain and unstable requirements. To select the best solution without trial-and-error, the U.S. navy has applied the set-based method for the early-phase design of a new ship-to-shore connector. The ship synthesis model plays an important role in applying the set-based method, but only a few countries possess this model and have prohibited this model from being transferred to other countries. This paper suggests a set-based method using a genetic algorithm and decision-making theory through benchmarking existing ship data. The algorithm was verified using the DDG-51 class ship synthesis model to optimize the weapon system design, which has been released for research purposes.

Determinants of Accessibility to Fintech Lending: A Case Study of Micro and Small Enterprises (MSEs) in Indonesia

  • SAPTIA, Yeni;NUGROHO, Agus Eko;SOEKARNI, Muhammad;ERMAWATI, Tuti;SYAMSULBAHRI, Darwin;ASTUTY, Ernany Dwi;SUARDI, Ikval;YULIANA, Retno Rizki Dini
    • The Journal of Asian Finance, Economics and Business
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    • v.8 no.10
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    • pp.129-138
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    • 2021
  • Several studies have revealed that information on borrower characteristics plays an important factor in approving their credit requests. Though the extent to which such characteritics are also applicable to the case of fintech lending remain uncertain. The aim of this study is, thus, to investigate the determinant factors that influence MSEs in obtaining credit through fintech lending. Here, we emphasize virtual trust in fintech lending encompasing the dimension of social network, economic attributes, and risk perception based on several indicators that are used as proxies. Primary data used in the study was gathered from an online survey to the respondents of MSEs in Java. The result of the study indicates that determinants of MSEs in obtaining credit from lender through fintech lending are statistically influenced by internet usage activities, borrowing history, loan utilization, annuity payment system, completeness of credit requirement documents and compatibility of loan size with the business need. These factors have a significant effect on credit approval because they can generate virtual trust of fintech lender to MSEs as potential borrowers. It concludes that the probability of obtaining fintech loans in accordance with their expectations are influenced by the dimensions of social network, economic attributes and risk perception.

An Empirical Analysis on the Structure and Conduct Methods of the World Rice Market: Focusing on the Top 4 Major Rice Exporting Countries (국제 쌀 시장에 대한 구조와 행위 분석: 주요 쌀 수출국들을 중심으로)

  • Kang, Hyunsoo
    • International Area Studies Review
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    • v.13 no.3
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    • pp.93-119
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    • 2009
  • The purpose of this paper is to analyze the world rice market through structure and conduct frameworks utilizing annual data from 1970 to 2007. The world rice market has been unstable for much of the period post-World War II, with prices volatile and the availability of supplies uncertain. Therefore, analysis of the structure and conduct of the world rice market can provide information to better formulate the direction of future policies. Also, this paper will describe the effects of total production, export rice price, market concentration, and real exchange rate for exporting countries on total export rice volume. On basis of the expected results, the international rice market possesses market power with respects to static calculation and hypothesis test, and it will be demonstrated that exporting countries' currency crucially affects the exporting quantity and market power of those same exporting countries.

Development of Demand Forecasting Model for Seoul Shared Bicycle (서울시 공유자전거의 수요 예측 모델 개발)

  • Lim, Heejong;Chung, Kwanghun
    • The Journal of the Korea Contents Association
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    • v.19 no.1
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    • pp.132-140
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    • 2019
  • Recently, many cities around the world introduced and operated shared bicycle system to reduce the traffic and air pollution. Seoul also provides shared bicycle service called as "Ddareungi" since 2015. As the use of shared bicycle increases, the demand for bicycle in each station is also increasing. In addition to the restriction on budget, however, there are managerial issues due to the different demands of each station. Currently, while bicycle rebalancing is used to resolve the huge imbalance of demands among many stations, forecasting uncertain demand at the future is more important problem in practice. In this paper, we develop forecasting model for demand for Seoul shared bicycle using statistical time series analysis and apply our model to the real data. In particular, we apply Holt-Winters method which was used to forecast electricity demand, and perform sensitivity analysis on the parameters that affect on real demand forecasting.

Subjective Recognition Types on Cancer Treatment Cost (암 비용에 대한 주관적 인식 유형)

  • Rhee, Young-Sun;Kim, Su-Yeon;Kim, Hye-Ji;Kim, Han-Na
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.7
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    • pp.281-290
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    • 2019
  • This study analyzed the recognition types of the economic burden for cancer treatment and the characteristics of each recognition type by employing Q methodology. For this study, we determined the final 45 Q statements by conducting literature surveys, internet searches and in-depth interviews. The P samples are 35 people of cancer patients, their family members, and experts. The Q statements were classified according to the forced normal distribution method and the collected data was analyzed using the PC QUANL program. For the analysis results, we extracted four recognition types on the economic burden of cancer treatment, and we named them 'uncertain anxiety', 'acceptance by family burden', 'object to challenge with active response' and 'insurance preparation', depending on their characteristics. The results of this study can be used as a basis for preparing the clinical intervention plan and the policies for cancer patients and the families involved in the fields of medicine, nursing and social welfare.

A Study on the Combination Effect of Herbal Medicine and Western Medicine on BPSD in Patients with Alzheimer's Disease: A Systematic Review (알츠하이머병 환자의 이상행동심리증상(BPSD)에 대한 한약과 양약의 병용 효과에 대한 연구: 체계적 문헌 고찰)

  • Kim, Man-Gi;Chang, Seok-Joo;Hong, Min-Ho;Kim, Geun-Woo;Koo, Byung-Soo
    • Journal of Oriental Neuropsychiatry
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    • v.31 no.4
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    • pp.301-314
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    • 2020
  • Objectives: The purpose of this study was to provide clinical evidence to support the use of herbal medicine combined with western medicine for BPSD. Methods: Studies were identified by searching CNKI, Pubmed, EMBASE, Cochrane Library, SCIENCEON, RISS, KMbase, KISS, OASIS. Literature searches of Chinese, English, and Korean databases were performed. Two authors independently extracted the data and evaluated the quality of each study. Results: The literature search identified 203 articles. Of these, 7 were selected for the analysis. The risk of bias in most studies was unclear. The most frequently used diagnostic tools were the NINCDS-ADRDA and DSM-IV. The most commonly used results indicator was NPI. In 6 of the 7 papers, combination treatment (herbal & Western medicine) was statistically significantly more effective than single treatment (Western medicine alone) for BPSD. No significant adverse events were reported. Conclusions: Herbal medicine in combination with Western medicine is more effective for treating BPSD than Western medicine alone. However, the quality of the studies used in this study was uncertain and the sample size was too small. Based on the findings of this study, more high-quality clinical trials are needed to confirm the efficacy of combination treatment.

Treatment Modality Based Survival in Gastric Carcinoma Patients with Stand-Alone Peritoneal Metastasis: a Case-Control Study

  • Jeong, Oh;Jung, Mi Ran;Kang, Ji Hoon
    • Journal of Gastric Cancer
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    • v.21 no.2
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    • pp.122-131
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    • 2021
  • Purpose: To date, there are no promising treatments for gastric carcinoma with peritoneal metastasis. Some researchers have suggested a survival benefit of gastrectomy in select patients. This study investigated the survival of gastric carcinoma patients with stand-alone peritoneal metastasis according to the type of treatment modality. Materials and Methods: We reviewed the data of 132 patients with gastric carcinoma and stand-alone peritoneal metastasis. We performed gastrectomy when the primary tumor was deemed resectable and systemic chemotherapy was administered. We analyzed patient survival according to the type of treatment, and the prognostic value of gastrectomy was evaluated in univariate and multivariate models. Results: Among all patients, 70 underwent gastrectomy plus chemotherapy, 20 underwent gastrectomy alone, 36 underwent chemotherapy alone, and 6 received supportive care. The median patient survival was 13 months. Patients who underwent gastrectomy had significantly longer survival than those who did not undergo gastrectomy (14 vs. 8 months, P<0.001). Patients who received chemotherapy showed significantly longer survival than those who did not (13 vs. 7 months, P=0.032). Patients who underwent gastrectomy plus chemotherapy showed better survival than those who underwent other treatments. In multivariate analysis, gastrectomy was found to be an independent prognostic factor (hazard ratio, 0.52; 95% confidence interval, 0.33-0.82) in addition to chemotherapy. Conclusions: Our study showed that patients who underwent gastrectomy plus chemotherapy had the best survival. Although the survival benefit of gastrectomy remains uncertain, it is a favorable prognostic indicator in patients with stand-alone peritoneal metastasis.