• 제목/요약/키워드: ultraviolet-irradiation

검색결과 544건 처리시간 0.031초

흰쥐에 조사한 자외선B가 Nitric Oxide의 활성에 미치는 효과 (I) (Effects of ultraviolet light B irradiation on nitric oxide activity in the sprague-dawley rat in vivo (I))

  • 민경옥;김중환
    • 대한물리치료과학회지
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    • 제6권3호
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    • pp.63-82
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    • 1999
  • Recent studies have revealed that Nitric oxide(NO) was one of the demonstration for the physiological regulator, endothelial derived relaxing factor(EDRF) and that NO was produced by ultraviolet irradiation in human. Thus, the present author have carried out a experimental study on the change of hematological, histological value of ultraviolet irradiation in sprague-dawley rats. The subjects were divided into four groups of ten rats each selected at random. There were 4 groups: 1. no irradiation control; 2. ultraviolet $75mJ/cm^2$ irradiation group; 3. ultraviolet $150mJ/cm^2$ irradiation group; 4. ultraviolet $225mJ/cm^2$ group. After a irradiation, hematological and histological tests were performed to observe erythrocyte, hemoglobin, hematocrit, MCH, MCHC, MCV, $O_2$ saturation, pH, $PO_2,\;PCO_2$ value and to observe histological changes. In hematological tests, erythrocyte, hemoglobin, hematocrit significantly increased in $75mJ/cm^2$ than control group and more $150mJ/cm^2$ ultraviolet irradiation group respectively. Also In blood gas tests, $PO_2$ significantly increased in $75mJ/cm^2$ and more $150mJ/cm^2$ group than control group. Whereas $PCO_2$ significantly decreased in $75mJ/cm^2$ and more $150mJ/cm^2$ group than control group (Duncan-Tukey test, P<0.05). In histological tests, control and $75mJ/cm^2$ group unchanged, but more $150mJ/cm^2$ group changed that it was cytolysis, cytotoxic effect, acanthosis, proliferation of keratinocyte, appearance of amorphous cell and pyknotic nucleus, production of sunburn cell. In conclusion, the present author results support the importance of the relation between NO effect and hematological, histological value by ultraviolet B irradiation.

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Flavonoid Compounds from Viola hondoensis and Their Effect on Matrix Metalloproteinase-1 in Ultraviolet Irradiation of Cultured Human Skin Fibroblasts

  • Moon, Hyung-In;Lee, Joong-Ku;Zee, Ok-Pyo;Chung, Jin-Ho
    • Food Science and Biotechnology
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    • 제14권1호
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    • pp.143-146
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    • 2005
  • Although many studies have been performed to elucidate the molecular consequences of ultraviolet irradiation, little is known about the effect of natural products. Ultraviolet irradiation is widely considered to be an environmental stress. Here we investigated the effect of 2',4',7-trihydroxyisoflavone on the regulation of MMP-1 and type 1 procollagen in Ultraviolet irradiation of cultured human dermal fibroblasts. Phytochemical investigation of the whole plants of Viola hondoensis led to the isolation of five flavonoids. The structures of these compounds were identified 2',4',5,7-tetrahydroxyisoflavone (1), 2',4',7-trihydroxyisoflavone (2), 4',7-dihydroxyflavone (3), isoorientin (4), and isovitexin (5) using spectroscopic analysis. Among these, 2',4',7-trihydroxyisoflavone reduced the expression of MMP-1 at the protein levels in a dose-dependent manner by ultraviolet irradiation. Taken together, our results suggest that 2',4',7-trihydroxyisoflavone an important role in the reduction of MMP-1 induction by ultraviolet irradiation.

Triterpenoid from Tiarella polyphylla, Regulation of Type 1 Procollagen and MMP-1 in Ultraviolet Irradiation of Cultured Old Age Human Dermal Fibroblasts

  • Moon, Hyung-In;Lee, Joong-Ku;Zee, Ok-Pyo;Chung , Jin-Ho
    • Archives of Pharmacal Research
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    • 제27권10호
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    • pp.1060-1064
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    • 2004
  • Although many studies have been performed to elucidate the molecular consequences of ultraviolet irradiation, little is known about the effect of natural products. Ultraviolet irradiation is widely considered to be an environmental stress. Here we investigated the effect of 3,23-dihydroxy- 20(29)-lupen-27-oic acid on the regulation of MMP-1 and type 1 procollagen in Ultraviolet irradiation of cultured old age human dermal fibroblasts. 3, 23-dihydroxy-20(29)-lupen-27- oic acid was isolated from Tiarella polyphylla D. Don (Saxifragaceae). Among them, 3, 23- dihydroxy-20(29)-lupen-27-oic acid induced the regulation of Type 1- procollagen and reduced the regulation of MMP-1 at the protein levels in a dose-dependent manner by ultraviolet irradiation. Taken together, our results suggest that 3, 23-dihydroxy-20(29)-lupen-27-oic acid plays an important role in the induction of Type 1-procollagen and reduction of MMP-1 by ultraviolet irradiation in old age human dermal fibroblasts.

자외선 조사에 의한 피부 반응의 디지털 영상분석 (Analysis of Digital Images of Skin Reaction Induced By Ultraviolet Irradiation)

  • 이동엽;두영택;이정우
    • 대한임상전기생리학회지
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    • 제8권2호
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    • pp.39-43
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    • 2010
  • Purpose : The purpose of this study was to analyze skin reactions induced by ultraviolet irradiation using digital imagery. Methods : We recruited 15 women and ultraviolet irradiation was applied to their lumbar area. (The degree of inflammatory reaction was set on the basis of the third erythema dose. Image analysis was divided by Photoshop CS (8 bit RGB scale and gray scale). Then, images were processes using Image Pro Plus 4.5 program analyzing R, G, B, chromatic red value, luminance value and gray value. Results : As a result of analyzing changes in RGB scale, there were statistically significant differences in R, G, and chromatic red values. As a result of analyzing changes in gray scale, there were statistically significant differences in gray value. Analysis of changes in B and luminance values showed that there was no statistically significant difference. Conclusion : This study found that ultraviolet irradiation had influence on RGB and gray scale. These results suggest that changes to digital images on skin reaction by ultraviolet irradiation are related to erythema. In particular, these changes are related to R and gray values.

폴리이미드막표면위에 경사진 자외선 조사를 이용한 네마틱 액정의 배향에 관한 연구 (A Study on Alignment of Nematic Liquid Crystal by Using Slanted Non-polarized Ultraviolet Light Irradiation on Polyimide Film)

  • 서대식;황율연;이보호
    • E2M - 전기 전자와 첨단 소재
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    • 제10권5호
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    • pp.461-466
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    • 1997
  • In this paper, we developed the new non-rubbing liquid crystal (LC) alignment techniques in the cell with slanted non-polarized ultraviolet (UV) light irradiation on polyimide (PI) film. It is shown that the uniform alignment for nematic (N) LC is obtained by using slanted non-polarized UV light irradiation on PI surface. We successfully obtained that the pretilt angle of NLC is generated about 3.3 degree in the cell with slanted non-polarized UV light irradiation with 70 degree on PI surface, for the first time. It is considered that the pretilt angle generation in NLC is attributed to interaction between the LC molecular and the PI, which is broken the polymer by slanted non-polarized UV irradiation. Therefore, we concluded that the uniform LC alignment is attributed to anisotropic dispersion force due to photo depolymerization with slanted non-polarized UV light irradiation on PI surface.

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A Study of Antibacterial Efficiency according to Direction of UV Irradiation in Cosmetic Case

  • Jeong, Jae Young;Hwang, You Jin
    • 한국컴퓨터정보학회논문지
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    • 제26권2호
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    • pp.119-124
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    • 2021
  • 본 연구에서는 자외선 조사 방향에 따른 화장품 살균 효율성을 확인하고자 하였다. 실험에는 그람양성균인 S.aureus에 대하여 자외선 살균의 실효 조사 각을 측정하였고 자외선 조사 방향에 따른 거리별 살균 영역의 변화를 연구하였다. 그리고 자외선 수평 조사 시 살균 효율을 높일 수 있는 방법으로서 누출 자외선을 반사시키는 방법을 제시해보았다. 그 결과 자외선 조사 각은 제품 설명에 비해 더 작게 측정되었고 자외선 조사 방향에 따른 살균 영역의 경우 수직 조사 시 시료와의 거리가 멀어질수록, 수평 조사 시 시료와의 거리가 가까울수록 살균 영역이 증가하였다. 또한 자외선 수평 조사 시 누출 자외선을 반사시키는 것으로 살균 효율을 높일 수 있는 것을 확인 하였다.

자외선 조사로 유발된 피부 염증성 반응에 맥동성 초음파가 미치는 영향 (The Effect of Pulsed Ultrasound on Skin Inflammatory Reaction Induced by Ultraviolet Irradiation)

  • 이정우;박수지;윤세원
    • The Journal of Korean Physical Therapy
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    • 제23권4호
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    • pp.53-58
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    • 2011
  • Purpose: This study aims to examine the effects of pulsed ultrasound on skin inflammatory reaction induced by ultraviolet irradiation. Methods: Twenty subjects were selected for this study. Inflammatory reaction was induced by ultraviolet irradiation in two areas of the lumbar region of the subjects. Pulsed ultrasound (3 MHz) was applied to one of the two areas of inflammatory reaction at a pulse ratio of 1:4, intensity of $0.5W/cm^2$, once a day for 5 min, and pulsed ultrasound was not applied to the other area. Wound color (chromatic red), luminance (gray) and wound contraction (area) were measured using digital imaging processing method. Results: There was a significant difference in wound color (chromatic red) in the interaction between time and area. There was a significant difference in luminance in the interaction between time and area. There was a significant difference in wound contraction between the two areas. Conclusion: These results indicate that pulsed ultrasound increased the wound contraction rate and reduced the inflammatory reaction activity such as erythema induced by ultraviolet irradiation.

제1형 당뇨토끼에서 자외선 혈액 조사 효과 (Effects of Ultraviolet Blood Irradiation in a Type 1 Diabetic Rabbit)

  • 양영석;김기범
    • 대한의용생체공학회:의공학회지
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    • 제40권3호
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    • pp.81-96
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    • 2019
  • The purpose of this study is to evaluate the effects of ultraviolet blood irradiation on the blood when a low dose of ultraviolet (UV) C is directly irradiated to the blood in a diabetic rabbit model and to evaluate the effects on treatment for diabetes. This study results indicate that the reduced body weight is increased and blood glucose levels are significantly reduced after the UBI treatment is performed when compared to those prior to the UBI treatment. In addition, $HCO_3{^-}$ levels and blood pH were elevated and lowered, respectively. When the UBI treatment is performed in a diabetic rabbit model, in this result indicate that blood glucose levels are reduced.

증착 중 자외광 노광에 의한 산화 아연 박막의 특성 변화 (The Effect of in situ Ultraviolet Irradiation on the Chemical Vapor Deposited ZnO Thin Films)

  • 김보석;백승재
    • 한국전기전자재료학회논문지
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    • 제29권4호
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    • pp.241-246
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    • 2016
  • ZnO thin films have wide application areas due to its versatile properties as transparent conductors, wide-bandgap n-type semiconductors, gas sensor materials, and etc. We have performed a systematic investigation on ultraviolet-assisted CVD (chemical vapor deposition) method. Ultraviolet irradiation during the deposition of ZnO causes chemical reduction on the growing surface; which results in the reduction of the deposition rate, increase in the surface roughness, and decrease of the electrical resistivity. These effects produce larger characteristic variation with various deposition conditions in terms of surface morphology and optical/electrical properties compared to normal CVD deposited ZnO thin films. This versatile controllability of ultraviolet-assisted CVD can provide a larger processing options in the fabrication of nano-structured materials and flexible device applications.