• 제목/요약/키워드: u-Transport

검색결과 406건 처리시간 0.025초

Binding Interaction Analysis of Neuromedin U Receptor 1 with the Native Protein Neuromedin U

  • Nagarajan, Santhosh Kumar;Madhavan, Thirumurthy
    • 통합자연과학논문집
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    • 제10권1호
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    • pp.14-19
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    • 2017
  • Neuromedin, a neuropeptide, which is involved in various functions that include contractile activity on smooth muscle, controlling the blood flow and ion transport in the intestine, increased blood pressure and regulation of adrenocortical function. It is involved in the pathophysiology of various immune mediated inflammatory diseases like asthma. In this study, we have performed protein-protein docking analysis of neuromedin U - neuromedin U receptor 1 complex. We have developed homology models of neuromedin U, and selected a reliable model using model validation. The model was docked with the receptor model, to analyse the crucial interactions of the complex. This study could be helpful as a tool in developing novel and potent drugs for the diseases related with neuromedin U receptor 1.

수용성 아미노메틸칼릭스아렌의 합성 및 방향족 물질의 통과실험 연구 (Syntheses and Arene Transport Studies of Water Soluble Aminomethylcalixarene)

  • 남계춘;김대순
    • 대한화학회지
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    • 제36권6호
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    • pp.933-940
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    • 1992
  • Calix[6]arene을 포름알데히드와 이차아민과 반응시키면 물에 녹는 칼릭세린 염기가 얻어진다. 이를 메틸요오드로 처리하여 암모늄 염을 만들고 다양한 친핵성 물질과 반응시키면 칼릭세린의 파라위치에 작용기가 포함된 calix[6]arene이 얻어진다. Calix[6]arene도 포름알데히드와 이차의 아릴아민과 반응시켜 물에 녹는 칼릭세린 아민을 만들었다. 이렇게 합성된 칼릭세린중 물에 녹는 아민과 산기가 포함된 calix[6]arene과 calix[8]arene을 운반체로 이용하여 중성의 방향족 물질들을 통과시키는 연구를 U 형태의 유리관을 이용하여 수행하였다. 방향족 기질들로는 나프탈렌, 안트라센, 파이렌, 풀우란텐 등의 고체물질을 사용하였다.

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Modeling the sensitivity of hydrogeological parameters associated with leaching of uranium transport in an unsaturated porous medium

  • Mohanadhas, Berlin;Govindarajan, Suresh Kumar
    • Environmental Engineering Research
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    • 제23권4호
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    • pp.462-473
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    • 2018
  • The uranium ore residues from the legacies of past uranium mining and milling activities that resulted from the less stringent environmental standards along with the uranium residues from the existing nuclear power plants continue to be a cause of concern as the final uranium residues are not made safe from radiological and general safety point of view. The deposition of uranium in ponds increases the risk of groundwater getting contaminated as these residues essentially leach through the upper unsaturated geological formation. In this context, a numerical model has been developed in order to forecast the $^{238}U$ and its progenies concentration in an unsaturated soil. The developed numerical model is implemented in a hypothetical uranium tailing pond consisting of sandy soil and silty soil types. The numerical results show that the $^{238}U$ and its progenies are migrating up to the depth of 90 m and 800 m after 10 y in silty and sandy soil, respectively. Essentially, silt may reduce the risk of contamination in the groundwater for longer time span and at the deeper depths. In general, a coupled effect of sorption and hydro-geological parameters (soil type, moisture context and hydraulic conductivity) decides the resultant uranium transport in subsurface environment.

텔레매틱스 시스템을 이용한 항공 및 항만 물류 정보 연계에 관한 연구;인천 첨단물류도시 대상 (A Study on Concatenation of Air & Sea Logistics' Information Using Telematics System;Case of Inchoen u-City)

  • 홍승범;김웅이
    • 한국항공운항학회지
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    • 제15권4호
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    • pp.100-107
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    • 2007
  • We proposed the concatenation of logistics' Information to constructing the intelligent logistics city that is to manage efficiently cargo distribution as providing at real-time information of cargo location trace and management through the Telematics/RFID. Case of the Incheon of the "Air Logistics Hub", this area is on an increasing trend on the quantity of cargo transport of the Air & Sea cargo system until 2006. As intelligent project of the Air's and the Sea's field is independently developed at each area, it is a problem on the concatenation of logistics' information such as freight location trace and management, operation management and route information of cargo vehicles. Therefore, we propose the advanced transport service model for the concatenating smoothly of Air & Sea cargo system. In this paper, we only manage the model of Air & Sea cargo system of the advance logistics city.

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MCCARD: MONTE CARLO CODE FOR ADVANCED REACTOR DESIGN AND ANALYSIS

  • Shim, Hyung-Jin;Han, Beom-Seok;Jung, Jong-Sung;Park, Ho-Jin;Kim, Chang-Hyo
    • Nuclear Engineering and Technology
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    • 제44권2호
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    • pp.161-176
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    • 2012
  • McCARD is a Monte Carlo (MC) neutron-photon transport simulation code. It has been developed exclusively for the neutronics design of nuclear reactors and fuel systems. It is capable of performing the whole-core neutronics calculations, the reactor fuel burnup analysis, the few group diffusion theory constant generation, sensitivity and uncertainty (S/U) analysis, and uncertainty propagation analysis. It has some special features such as the anterior convergence diagnostics, real variance estimation, neutronics analysis with temperature feedback, $B_1$ theory-augmented few group constants generation, kinetics parameter generation and MC S/U analysis based on the use of adjoint flux. This paper describes the theoretical basis of these features and validation calculations for both neutronics benchmark problems and commercial PWR reactors in operation.

금강 부유물중 미량 금속의 함량과 이동 (Trace Metals of Suspended Particulate Matters in the Keum River)

  • 최만식;이창복
    • 한국해양학회지
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    • 제30권5호
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    • pp.371-381
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    • 1995
  • 금강 기원 부유물중 금속의 함량과 이동양상을 파악하기 위하여 상류의 한 지점에 서 1년 동안 총 18개 부유물 시료를 주기적으로 채취하였으며, 이를 대상으로 주성분 원소(Al, Fe, P, Mn)와 미량 원소(Cr, Co, Ni, Cu, Zn, Cd, Pb, U)를 분석하였다. Al 및 Fe을 제외한 금속들의 함량은 계절에 따라 큰 폭으로 변화하였으며, 유랑이 작고 부유물 농도가 낮은 겨울철에 최대값을, 부유물 농도가 높은 홍수기와 봄철에 최소값 을 보였다. 각 금속별 함량은 중국의 황하와 양자강의 부유물에 비해 Fe, Co, Cr, Cu 및 N은 비슷하였으나 Mn, Zn, Cd, Pb 및 U의 함량은 금강에서 매우 높았다. 이러한 하 천간 금속함량 차이는 집수역의 지질(U) 및 인위적인 영향의 차이(Mn, Pb) 때문으로 해석된다. 금강을 통한 입자상 금속의 이동량은 부유물 농도가 높은 홍수기에 가장 큰 값을 보였으며, Mn, P 및 Cd을 제외한 모든 금속에서 풍수기 동안 이동되는 양이 전체 이동량의 7% 이상을 차지하였다. 이동 형태별 금속의 이동량을 파악하기 위하여 부유 물중 금속의 존재형태를 쇄절성 및 비쇄설성 부분으로 나누었고, 각 부분의 이동량을 용존상과 함께 비교하였다. 각 금속별 용존상과 비쇄설성 부분의 합이 차지하는 비율 은 총 이동량의 50%(Co)에서 92%(Mn) 범위였으며, Mn>Cd, U>Cu>Zn>Ni>Pb>Co 순으로 이 부분의 비율이 감소하였다.

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새로운 컨테이너 이송차량 기술대안 개발 (Development of Technical Alternative on the Container Transport Vehicle of New Type)

  • 김우선;최용석
    • 한국항해항만학회:학술대회논문집
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    • 한국항해항만학회 2006년도 춘계학술대회 및 창립 30주년 심포지엄(논문집)
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    • pp.367-372
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    • 2006
  • 본 연구의 목적은 기존의 컨테이너터미널 이송차량의 기술대안을 분석하여 터미널 생산성을 높일 수 있는 새로운 이송차량 대안을 개발하는 것이다. 대안 개발을 위해 YT(Yard Trailer), S/C(Straddle Carrier), SHC(Shuttle Carrier), AGV(Automated Guided Vehicle) 등의 이송차량에 대한 기술적 사양을 분석하며, 이송차량의 기술단계별 세대를 분류하기 위하여 운영과 성능을 조사한다. 본 연구에서 제시하는 이송차량의 개발 대안은 향후 고생산성의 진보된 컨테이너 터미널에 유용 할 것이다.

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제3회 전국기술사대회 특집(3차분) - U-City 개요 - 건축전기설비 - (The 3rd National Conference Of Professional engineers - Outline of U-City)

  • 윤길재
    • 기술사
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    • 제42권6호
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    • pp.28-30
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    • 2009
  • There is a proverb in Korea "Don't chase after another." It can be a right proverb in sometimes. However, usually it doesn't fit in these various society, information knowledge society. Modern society requires convergence technology. IBS (Intelligent Building System) requires knowledge of architecture field, electric field, communication field, and computation field. ITS (Intelligent Transport Systems) which is constructing in many cities requires various knowledge as engineering works, electricity, computation, communication and transportation. In the case of u-City, it requires technology of many fields as architecture, electricity, communication, engineering works, transportation, and computation. Anyone who wants to participate in u-City should study and acquire knowledge in various field. Otherwise, it must be failed because of lack of communication like as the Tower of Babel. U-City is not a portion of one field. Therefore, engineers in many fields should cooperate with each other to make u-city as the best product in the world.

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