• 한국IT서비스학회:학술대회논문집
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• 2009.05a
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• pp.91-105
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• 2009

현 정부는 신성장동력의 녹색기술산업 분야에서 첨단그린도시를 선정하여, 향후 많은 지자체 등에서 앞다투어 U-City 건설을 목표로 많은 서비스를 도입할 것으로 예상된다. 그러나, U-City 서비스, 프로세스, 필요한 H/W 등에 대한 표준화는 이루어져 있지 않은 상황이다. 이에 본 연구에서는 U-City 건설에 활용될 수 있는 IT 기반의 U-City 서비스 개발 방법론을 제안하고자 한다. 이를 위해 본 연구에서는 U-City와 NSD(New Service Development) 방법론들에 대한 문헌연구를 중심으로 U-City Service 개발 방법론 도출을 위한 분석을 하였다. 이러한 U-City 서비스 개발 방법론 연구결과를 통하여 U-City 서비스 도입을 위한 지침서를 제공할 수 있는 토대를 마련할 것이다.

• Clinical and Experimental Pediatrics
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• v.61 no.1
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• pp.24-29
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• 2018

Purpose: The aim of this study was to evaluate the diagnostic accuracy of urinary biomarkers, such as neutrophil gelatinase-associated lipocalin (uNGAL) and ${\beta}-2$ microglobulin (uB2MG), in early detection of urinary tract infection (UTI) in infants aged <3 months with fever. Methods: A total of 422 infants aged <3 months (male:female=267:155; mean age, 56.4 days), who were admitted for fever, were retrospectively included in this study. We compared uNGAL and uB2MG between the UTI and non-UTI groups at the time of admission. The sensitivity, specificity, accuracy, and area under the curve (AUC) of uNGAL and uB2MG for use in diagnosing UTI were assessed. Results: Among 422 patients, 102 (24.2%) were diagnosed with UTI. Levels of uNGAL were higher in the UTI group than in the non-UTI group (366.6 ng/mL vs. 26.9 ng/mL, P<0.001). Levels of uB2MG were not different between the 2 groups. Multivariate analysis revealed that uNGAL was an independent predictive factor for UTI (P=0.033). The sensitivity, specificity, and accuracy were 90.2%, 92.5%, and 91.9% for uNGAL, and 48.0%, 43.8%, and 44.8% for uB2MG, respectively. AUC of uNGAL was 0.942 and that of uB2MG was 0.407. Conclusion: Accuracy of uNGAL in the diagnosis of UTI is high in febrile infants aged <3 months. uNGAL can help in the early diagnosis and treatment of UTI in infants.

• The Pure and Applied Mathematics
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• v.21 no.3
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• pp.147-163
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• 2014

In this paper, we study the existence of positive solutions for singular impulsive differential equations with integral boundary conditions $$\{u^{{\prime}{\prime}}(t)+q(t)f(t,u(t),u^{\prime}(t))=0,\;t{\in}\mathbb{J}^{\prime},\\{\Delta}u(t_k)=I_k(u(t_k),u^{\prime}(t_k)),\;k=1,2,{\cdots},p,\\{\Delta}u^{\prime}(t_k)=-L_k(u(t_k),u^{\prime}(t_k)),\;k=1,2,{\cdots},p,\\u=(0)={\int}_{0}^{1}g(t)u(t)dt,\;u^{\prime}=0,$$) where the nonlinearity f(t, u, v) may be singular at v = 0. The proof is based on the theory of Leray-Schauder degree, together with a truncation technique. Some recent results in the literature are generalized and improved.

• Proceedings of the KIEE Conference
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• 1987.07a
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• pp.205-208
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• 1987

• Proceedings of the Korea Information Processing Society Conference
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• 2010.04a
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• pp.922-925
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• 2010

u-Health 기술의 표준화 추진 및 국내 자체의 원천 기술 개발을 위한 노력이 지속적으로 이루어지는 시점에서 이에 따른 u-Health 소프트웨어의 품질평가 요구에 대응하기 위해, 본 연구에서는 u-Health 소프트웨어 분야 기반기술을 조사하고 u-Health 소프트웨어 기능성 평가모델을 개발하고자 한다.

• Bulletin of the Korean Mathematical Society
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• v.60 no.6
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• pp.1523-1537
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• 2023

Let R be a commutative ring with identity and S a multiplicative subset of R. First, we introduce and study the u-S-projective dimension and u-S-injective dimension of an R-module, and then explore the u-S-global dimension u-S-gl.dim(R) of a commutative ring R, i.e., the supremum of u-S-projective dimensions of all R-modules. Finally, we investigate u-S-global dimensions of factor rings and polynomial rings.

• Molecules and Cells
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• v.38 no.2
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• pp.156-162
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• 2015

Urokinase plasminogen activator (uPA) and urokinase plasminogen activator receptor (uPAR) play a major role in the infiltrative growth of glioblastoma. Downregulatoion of the uPA and uPAR has been reported to inhibit the growth glioblastoma. Here, we demonstrate that tristetraprolin (TTP) inhibits the growth of U87MG human glioma cells through downregulation of uPA and uPAR. Our results show that expression level of TTP is inversely correlated with those of uPA and uPAR in human glioma cells and tissues. TTP binds to the AU-rich elements within the 3' untranslated regions of uPA and uPAR and overexpression of TTP decreased the expression of uPA and uPAR through enhancing the degradation of their mRNAs. In addition, overexpression of TTP inhibited the growth and invasion of U87MG cells. Our findings implicate that TTP can be used as a promising therapeutic target to treat human glioma.

• 대한예방의학회:학술대회논문집
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• 2000.10a
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• pp.233-233
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• 2000

• 대한예방의학회:학술대회논문집
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• 2000.10a
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• pp.234-235
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• 2000

• 대한예방의학회:학술대회논문집
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• 2000.10a
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• pp.231-232
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• 2000