• Journal of the Korean Society of Clothing and Textiles
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• v.17 no.4
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• pp.587-601
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• 1993

In the order to grasp their physical characteristics stemming from activity amount, this paper has divided elderly women into the following group ; those with high activity in the past, those with low activity in the present, those with high activity in the present and those with low activity in the present. The analyses of the body measurements and the pie chart, and the classification of back shapes by taking photographs have led to the following results. 1. The items of depth and girth among the body measurements were significant in the past and the present activity. Those with high activity in the past had smaller sizes in depth and girth than those with low activity. 2. From the pie chart, it was shown that those with high activity in the past had smaller sizes in every index as well as in girth than those with low activity in the past. Both those with low activity in the present and those with medium activity in the present had somewhat large sizes in waist girth, bust girth, hip girth and abdominal girth and in the indices of these items. 3. The classification of back shapes by taking photograpes has shown that those with high activity in the past had the less bent body type-42 percent of Type A and 6.5 percent of Type D. Among those with medium activity in the present, Type A was most outstanding and Type C and Type D were less, This fact shows that those with medium activity in the present keep the most normal body type. This proves that the medium activity of elderly women is desirable for keeping the normal body type.

• Journal of Families and Better Life
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• v.14 no.2
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• pp.127-138
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• 1996

The purpose of this study is to show farm women's stress under productive activity role multiple overload through family characteristic (pattern and number) and characteristic(type working time and involvement proportion) of productive activity. The outline of the study is as follow; 1. Stress by pattern and number of a family is highest in a four generation family and increases according as the number of the family increases. 2. The characteristic of productive activity : 1) Stress based on type of productive activity is highest in Type III of the most multiple overload roles. 2) in light of stress based working time area of household task activity is in inverse proportion to working time but area of farming and wage earning activity are approximately in direct proportion to it. The two-way ANOVA analysis show that stress in Type I of area of household task increases but in Type IV it decreases as working time increases 3) In stress based on involvement proportion to it. The wo-way ANOVA analysis show that stress in Type I of area of household task increases but in Type IV it decreases as working time increases. 3) In stress based on involvement proportion in three as working time increases 3). In stress based on involvement proportion in three activity areas the more the involvement proportion the less of the stress : an inverse ratio.

• YAKHAK HOEJI
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• v.38 no.2
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• pp.211-217
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• 1994

Copper intoxication and disturbance of copper metabolism induced various oxygen-derived free radicals related damages. The effect of copper ion on xanthine oxidase activity and type conversion of the enzyme which is concerned to generation of reactive oxygen species, was investigated, It was observed that xanthine oxidase activity was increased by addition of copper ion in the reaction mixture in proportional to the concentration of the metal ion until $60\;{\mu}M$, while the enzyme activity was inhibited in higher concentration of copper treatment. On the other hand, xanthine dehydrogenase activity was inhibited by copper ion addition with concentration dependently. Preincubation of enzyme source with $30\;{\mu}M$ of copper ion, which concentration marked increased the xanthine oxidase activity, unchanged the enzyme activity and type conversion compare to control in vitro system. It was also observed that copper induced xanthine oxidase activity and the enzyme type conversion was protected by dithiothreitol and penicillamine. These results indicate that the increment of the type conversion of xanthine oxidase necessarilly need the presence of copper ion in enzyme assay system.

• YAKHAK HOEJI
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• v.47 no.6
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• pp.456-460
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• 2003

In vitro $\beta$-lactamase inhibitory activity of 6-exomethylenepenam compounds ( 1, 2, 3, 4 and 5) was compared with clavulanic acid, sulbactam and tazobactam. The inhibitory activity of compound 3 was stronger than those of sulbactam and clavulanic acid against Type I and II enzymes and stronger than tazobactam against Type III, IV, TEM enzymes. The inhibitory activity of 5 was stronger than sulbactam and clavulanic acid against Type I and II enzymes and stronger than tazobactam against Type III, and IV enzymes. The in vitro antimicrobial activity of 3, 4 and 5 combined with ampicillin and cefoperazone was compared with the sulbactam against $\beta$-lactamase producing 27 strains. But, synergistic activity of 3 and 5 was inferior to tazobactam.

• YAKHAK HOEJI
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• v.46 no.6
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• pp.387-391
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• 2002

In vitro $\beta$-lactamase inhibitory activity of 6-exomethylene sulbactam compounds (CH-120, 130, 140, 145, 150, 155) was compared with clavulanic acid, sulbactam and tazobactam. The inhibitory activity of CH-140 was stronger than sulbactam and clavulanic acid against Type II, III, IV, TEM enzymes and stronger than tazobactam against Type IV enzyme. The inhibitory activity of CH-145 was stronger than sulbactam and clavulanic acid against Type I, II, III, IV, TEM enzymes and stronger than tazobactam against Type III, IV enzymes. The in vitro antimicrobial activity of CH-140 and CH-145 combined with piperacillin and ceftriaxone was compared with the sulbactam and tazobactam against $\beta$-lactamase producing 31 strains. But, synergistic activity of CH-140 and CH-145 was inferior to tazobactam.

• Journal of the East Asian Society of Dietary Life
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• v.5 no.3
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• pp.215-221
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• 1995

This study was undertaken to investigate the effect of Taraxacum herba extract on the hepatic xanthine oxidase activity as a oxygen free radical generating enzyme in vitro and in vivo. It was observed that partial purified hepatic xanthine oxidase (type O) activity was strongly inhibited by the addition of Taraxacum herba n-butanol extract in vitro. The Km value of xanthine oxidase without affecting the Vmax value for xanthine was significantly increased by the addition of ta-dase (type O) activity was significantly inhibited by the treatment of Taraxacum gerba n-butanol ex-tract for 5days(over 40mg/kg, i.p), whereas, xanthine oxidase (type D) activity was not changed by the injection of Taracacum herba n-butanol extract. Meanwhile, liver weight / body weight(%), serum alanine aminotransferase activity and hepatic lipid peroxide content in Taraxacum herba n-buta-nol extract-treated rat were not changed. These findings led us to conclude that Taraxacum herba n-butanol extract may regulate the hepatic xanthine oxidase type O activity to prevent toxic effect of oxidative stress by the oxygen free radicals.

• Journal of the Korean housing association
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• v.25 no.4
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• pp.83-91
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• 2014

The purpose of this study is to clarify the characteristics between the type of daily routine and spatial configuration of activity areas in classroom and provide alternatives for space planning of activity areas in classroom of child-care centers. This study used the content analysis on daily activity plan and floor plans through field survey. Analysis on floor plans was conducted for 35 classrooms in 9 child-care centers which allowed field survey. The results of this study were as follows; There was no significant difference for classroom size according to the type of daily routine in 3 to 5-year-old classrooms. The average size of classrooms was $61.6m^2$ for care oriented type, $41.4m^2$ for indoor activity oriented type and $48.8m^2$ for group activity oriented type. There was no significant difference in composition of activity areas in classrooms according to the type of daily routine. In case of 0 to 2-year-old classrooms, they were composed of 6 activity areas including gross-motor, role play, block building, language, creative expression, exploration/manipulation. Activity area of the most low frequency was gross-motor area. In case of 3 to 5-year-old classrooms, most classrooms were composed of all the 7 activity areas including art, tone and rhythmic, block building, role play, language, math and science. Most accessible and central areas in 0 to 2-year-old classrooms were gross-motor and role play. Also, most separate areas were exploration/manipulation and block building. Most accessible and central areas in 3 to 5-year-old classroom were art and math. Also, most separate areas were tone and rhythmic and science.

• YAKHAK HOEJI
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• v.23 no.3_4
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• pp.159-166
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• 1979

Twelve derivatives of PAS-sulfonamide were synthesized and tested for their antibacterial activity against various bacterial strains. The derivatives XII and XIV showed relatively potent antibacterial activity to INAH-R strains and INAH-PAS-R strains and type XII to streptococcal strains; type IX and type VI to Pseudomonas aeruginosa.

• Journal of the Korea Fashion and Costume Design Association
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• v.11 no.1
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• pp.111-121
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• 2009

The purpose of this study is to investigate the effect of body type(thin, standard, fat), necktie width(narrow, medium, wide), gender(man, woman) on image formation. Sets of stimulus and response scales(7 point semantic) were used as experimental materials. The stimuli were 9 color pictures manipulated with the combination of necktie-width and body type using computer simulation. The subjects were 116 male undergraduates and 99 female undergraduates living in Gyeongsangnam-do. Image factor of the stimulus was composed of 4 different components, young-activity, attractiveness-gracefulness, stability, and boldness. In the young-activity, attractiveness-gracefulness and stability, body type and necktie-width showed independent effect. In the boldness, body type showed independent effect. Significant interaction effects of body type and necktie-width on young-activity, attractiveness-gracefulness and stability were found. For young-activity image, necktie of narrow width were effective. For attractiveness-gracefulness image, body type of standard were effective. For stability image, body type of standard and body type of thin on necktie of narrow and medium width were effective. The male fashion image can be perceived differently according to combination of the clues used in body type and necktie-width. Therefore, when the male fashion to create images that will have to consider the body type and necktie width.

• The Korean Journal of Physiology and Pharmacology
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• v.24 no.3
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• pp.203-212
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• 2020

Promyelocytic leukemia (PML) gene, through alternative splicing of its C-terminal region, generates several PML isoforms that interact with specific partners and perform distinct functions. The PML protein is a tumor suppressor that plays an important role by interacting with various proteins. Herein, we investigated the effect of the PML isoforms on oncostatin M (OSM)-induced signal transducer and activator of transcription-3 (STAT-3) transcriptional activity. PML influenced OSM-induced STAT-3 activity in a cell type-specific manner, which was dependent on the p53 status of the cells but regardless of PML isoform. Interestingly, overexpression of PML exerted opposite effects on OSM-induced STAT-3 activity in p53 wild-type and mutant cells. Specifically, overexpression of PML in the cell lines bearing wild-type p53 (NIH3T3 and U87-MG cells) decreased OSM-induced STAT-3 transcriptional activity, whereas overexpression of PML increased OSM-induced STAT-3 transcriptional activity in mutant p53-bearing cell lines (HEK293T and U251-MG cells). When wild-type p53 cells were co-transfected with PML-IV and R273H-p53 mutant, OSM-mediated STAT-3 transcriptional activity was significantly enhanced, compared to that of cells which were transfected with PML-IV alone; however, when cells bearing mutant p53 were co-transfected with PML-IV and wild-type p53, OSM-induced STAT-3 transcriptional activity was significantly decreased, compared to that of transfected cells with PML-IV alone. In conclusion, PML acts together with wild-type or mutant p53 and influences OSM-mediated STAT-3 activity in a negative or positive manner, resulting in the aberrant activation of STAT-3 in cancer cells bearing mutant p53 probably might occur through the interaction of mutant p53 with PML.