• Title/Summary/Keyword: two sample t-test

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Clinical Efficacy of Erdosteine in Patients with Acute or Chronic Bronchitis -A Randomized, Double Blind, Comparative Study vs. Ambroxol- (급.만성 기관지염 환자에서 엘도스$^{(R)}$(Erdosteine)의 임상효과 -염산 암브록솔과의 무작위 이중맹검 비교시험-)

  • Kim, Seok-Chan;Lee, Sang-Hoak;Song, So-Hyang;Kim, Young-Kyoon;Moon, Hwa-Sik;Song, Jeong-Sup;Park, Sung-Hak
    • Tuberculosis and Respiratory Diseases
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    • v.44 no.6
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    • pp.1296-1307
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    • 1997
  • Background : Erdosteine is a thiol derivative developed for the treatement of chronic obstructive bronchitis, including acute infective exacerbation of chronic bronchitis. Erdosteine has mucomodulating and antioxidant properties and especially exhibits excellent gastrointestinal tolerability. Methods : The study was conducted as a prospective evaluation, with 2 comparative groups orally treated with erdosteine 300mg (bid.) or ambroxol 30mg (b.i.d.) for 7 days and the design of trial was double-blind. The treatments have been assigned randomly to patients (n=80) with acute or chronic bronchitis. The primary end-point used to determine efficacy in this study was subjective symptoms including expectorating frequence, expectoration volume, expectorating difficulty, expectoration viscosity, cough intensity and dyspnea. The secondary end-points of efficacy was the result of arterial blood gas analysis and pulmonary function test. Safety was evaluated with adverse drug reactions and laboratory tests monitoring. 61 patients was included in the efficacy analysis, due to the fact that 19 patients drop-out for different reasons. The obtained values have been analyzed with paired Hest., ANOVA test., multivariate $t^2$-test, repeated measures analysis of covariance, two sample t-test, loglinear-logit model analysis, Fisher's exact test. Results : 1) There was no significant difference on demographic data and vital signs between erdosteine and ambroxol treated groups. 2) The comparison between erdosteine and ambroxol treated groups showed no significant difference in improvement of each symptom in spite of the more favorable efficacy obtained with erdosteine. No difference on the contrary was observed for arterial blood gas analysis and pulmonary function test. 3) As safety is concerned, no clinical significant changes in laboratory test and symptom were induced in erdosteine and ambroxol treated group and two patients in ambroxol treated group drop-out for adverse reactions in symptom. 4) In the evaluation of final clinical efficacy, erdosteine improved more effectively patient's overall symptoms {very good effect (11/31), good effect (12/31), moderate effect (6/31), no effect (2/31), aggravation (0/31)} than ambroxol {very good effect (6/30), good effect (14/30), moderate effect (5/30), no effect (4/30), aggravation (2/30)}. And the probability of symptomatic improvement by erdosteine compared to ambroxol was 2.5 times. (p<0.05). Conclusion : This study showed that erdosteine was clinically effective and safe drug for treatment of acute and chronic bronchitis.

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An empirical study on a firm's fail prediction model by considering whether there are embezzlement, malpractice and the largest shareholder changes or not (횡령.배임 및 최대주주변경을 고려한 부실기업예측모형 연구)

  • Moon, Jong Geon;Hwang Bo, Yun
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.9 no.1
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    • pp.119-132
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    • 2014
  • This study analyzed the failure prediction model of the firms listed on the KOSDAQ by considering whether there are embezzlement, malpractice and the largest shareholder changes or not. This study composed a total of 166 firms by using two-paired sampling method. For sample of failed firm, 83 manufacturing firms which delisted on KOSDAQ market for 4 years from 2009 to 2012 are selected. For sample of normal firm, 83 firms (with same item or same business as failed firm) that are listed on KOSDAQ market and perform normal business activities during the same period (from 2009 to 2012) are selected. This study selected 80 financial ratios for 5 years immediately preceding from delisting of sample firm above and conducted T-test to derive 19 of them which emerged for five consecutive years among significant variables and used forward selection to estimate logistic regression model. While the precedent studies only analyzed the data of three years immediately preceding the delisting, this study analyzes data of five years immediately preceding the delisting. This study is distinct from existing previous studies that it researches which significant financial characteristic influences the insolvency from the initial phase of insolvent firm with time lag and it also empirically analyzes the usefulness of data by building a firm's fail prediction model which considered embezzlement/malpractice and the largest shareholder changes as dummy variable(non-financial characteristics). The accuracy of classification of the prediction model with dummy variable appeared 95.2% in year T-1, 88.0% in year T-2, 81.3% in year T-3, 79.5% in year T-4, and 74.7% in year T-5. It increased as year of delisting approaches and showed generally higher the accuracy of classification than the results of existing previous studies. This study expects to reduce the damage of not only the firm but also investors, financial institutions and other stakeholders by finding the firm with high potential to fail in advance.

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The Effect of the Educational Program on Caring-Confidence and Rearing Attitude in Mothers with Newborns (신생아 돌보기 교육이 어머니의 자신감과 양육태도에 미치는 효과)

  • Cho Kyoul-Ja;Lee Kun Ja;Lee Ohk Jaa
    • Child Health Nursing Research
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    • v.5 no.1
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    • pp.84-96
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    • 1999
  • The purpose of this study was to find whether the educational program contributed to the increase of caring confidence and rearing attitude of the newborn mothers. The subjects for this study were 40 newborn mothers-20 control group and 20 experimental group-who delivered a normal neonate and were gotten general informations from the nurses at the K medical center in Seoul. Especially, the experimental group was educated for 30-40 minutes in maternal educational program through lectures, demonstrations, discussion with textbooks and visual materials by a researcher at 2-3 days after delivery. The data were collected two times-at 2-3 days after delivery and at 4 weeks after discharge-from October, 1998 to January, 1999 by investigators interviewing with a structured questionnaire. Pharis(1978)'s self confidence scale was used after some modification to measure caring confidence and Cohler's maternal attitude scale to check mother's rearing attitude. Analysis of data was done by using of frequency, %, x²-test, Independent sample t-test. The results of this study were as follows ; 1. The Confidence of the experimental group was significant higher than the control group (t=2.519, p=.016) and the rearing attitude changed more positively(t=5.545, p=.000). 2. In the confidence scale, the statements having a significant change were holding a baby, changing diapers, feeding, and caring umblicus. 3. In the rearing attitude scale, the statements having a significant change were 12 of 20 statements.

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Technology Teachers' Motivation toward Teaching Biotechnology (생물기술교육에 대한 기술교사의 동기유발)

  • Kwon, Hyuksoo
    • 대한공업교육학회지
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    • v.34 no.1
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    • pp.252-273
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    • 2009
  • Due to the importance of biotechnological literacy, the educational community in fields such as technology education, science education, and agricultural education has acknowledged the importance of biotechnology instruction for secondary school. Although recognized as a content organizer in the field of technology education, the actual teaching of biotechnology has not been broadly implemented in technology education classes. In the perspective of expectancy-value theory, technology teachers' motivation is the key factor for affecting the biotechnology instruction. This study investigates Korean technology teachers' motivational beliefs toward biotechnology and its instruction and their perceived ability and value toward biotechnology learning contents. To measure their motivational beliefs and attitudes, a composite on-line survey (fifteen motivational beliefs items, eight biotechnology content items, and related demographic items) was developed. Based on 114 Korean technology teachers' responses the researcher performed a descriptive analysis, independent t-test, and factor analyses (exploratory and confirmatory factor analysis using M-plus 5.0 and SPSS 16.0). Korean technology teachers' abilities toward eight biotechnology contents indicated lowscores while their values were relatively high. Through the independent sample t-test by two demographic variables (gender and professional development), this study found several significant differences in the perceived value. As a preliminary finding of exploratory factor analysis, fifteen items was separated into two motivational constructs of expectancy (6 items) and value (8 items). One item (item #6) was eliminated due to the cross loading. The final findings of this study may have significant implications for professional development regarding biotechnology and its instruction (both in-service and pre-service training) of technology teachers. Also, the confirmatory facctor analysis supported the preliminary finding. Finally, this study recommends that a validity test for other population, investigation for motivational sub-constructs, and in-depth investigation toward biotechnology instruction.

Accident Models of Rotary by Vehicle Type (차량유형별 로터리 사고모형)

  • Han, Su-San;Park, Byeong-Ho
    • Journal of Korean Society of Transportation
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    • v.29 no.6
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    • pp.67-74
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    • 2011
  • This study deals with the traffic accidents data from the Korean rotaries (circular intersections) to verify their characteristics affected by different vehicle types. This paper categorized the data into three groups based on vehicle types, and developed a set of accident models. The paper proposed two ZIP models and one negative binomial model through a statistical analysis for three vehicle types: automobile, truck and van, and others. The differences among those models were then statistically compared.

Correlates of Peer Victimization in Boys and Girls - Maternal Parenting and Children's Self-Esteem (남녀 아동의 또래괴롭힘과 관련된 변인들 -어머니의 양육행동과 아동의 자아존중감)

  • Doh Hyun-Sim;Kim Sun-Mi
    • Journal of Families and Better Life
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    • v.24 no.4 s.82
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    • pp.117-126
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    • 2006
  • This study examined the relations of maternal parenting and children's self-esteem to peer victimization as well as the gender differences in peer victimization. A sample of 494 5th- and 6th-grade children in Pusan answered three kinds of questionnaires regarding maternal parenting, children's self-esteem, and peer victimization. Peer victimization consisted of two constructs, bullying and victimization by pun. Data were analyzed by independent samples t-test and correlations. Boys showed more overt bullying and victimization by peers than girls, but relational peer victimization didn't vary as a function of the gender. Overall, the more boys and girls perceived their mothers as rejective/restricted, protective, and physically abusive, the more they were bullied and victimized. Both boys and girls were bullied and victimized by their peers when they showed lower self-esteem. Especially self-esteem was more highly correlated with victimization by peers than bullying.

Evaluation of the effect of two different occlusal splints on maximum occlusal force in patients with sleep bruxism: a pilot study

  • Karakis, Duygu;Dogan, Arife;Bek, Bulent
    • The Journal of Advanced Prosthodontics
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    • v.6 no.2
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    • pp.103-108
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    • 2014
  • PURPOSE. The occlusal splint has been used for many years as an effective treatment of sleep bruxism. Several methods have been used to evaluate efficiency of the occlusal splints. However, the effect of the occlusal splints on occlusal force has not been clarified sufficiently. The purpose of this study was to evaluate the effect of occlusal splints on maximum occlusal force in patients with sleep bruxism and compare two type of splints that are Bruxogard-soft splint and canine protected hard stabilization splint. MATERIALS AND METHODS. Twelve students with sleep bruxism were participated in the present study. All participants used two different occlusal splints during sleep for 6 weeks. Maximum occlusal force was measured with two miniature strain-gage transducers before, 3 and 6 weeks after insertion of occlusal splints. Clinical examination of temporomandibular disorders was performed for all individuals according to the Craniomandibular Index (CMI) before and 6 weeks after the insertion of splints. The changes in mean occlusal force before, 3 and 6 weeks after insertion of both splints were analysed with paired sample t-test. The Wilcoxon test was used for the comparison of the CMI values before and 6 weeks after the insertion of splints. RESULTS. Participants using stabilization splints showed no statistically significant changes in occlusal force before, 3, and 6 weeks after insertion of splint (P>.05) and participants using Bruxogard-soft splint had statistically significant decreased occlusal force 6 weeks after insertion of splint (P<.05). There was statistically significant improvement in the CMI value of the participants in both of the splint groups (P<.05). CONCLUSION. Participants who used Bruxogard-soft splint showed decreases in occlusal force 6 weeks after insertion of splint. The use of both splints led to a significant reduction in the clinical symptoms.

Preliminary Psychometric Properties of the Chinese Version of the Work-Related Quality of Life Scale-2 in the Nursing Profession

  • Lin, Shike;Chaiear, Naesinee;Khiewyoo, Jiraporn;Wu, Bin;Johns, Nutjaree Pratheepawanit
    • Safety and Health at Work
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    • v.4 no.1
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    • pp.37-45
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    • 2013
  • Objectives: As quality of work-life (QWL) among nurses affects both patient care and institutional standards, assessment regarding QWL for the profession is important. Work-related Quality of Life Scale (WRQOLS) is a reliable QWL assessment tool for the nursing profession. To develop a Chinese version of the WRQOLS-2 and to examine its psychometric properties as an instrument to assess QWL for the nursing profession in China. Methods: Forward and back translating procedures were used to develop the Chinese version of WRQOLS-2. Six nursing experts participated in content validity evaluation and 352 registered nurses (RNs) participated in the tests. After a two-week interval, 70 of the RNs were retested. Structural validity was examined by principal components analysis and the Cronbach's alphas calculated. The respective independent sample t-test and intra-class correlation coefficient were used to analyze known-group validity and test-retest reliability. Results: One item was rephrased for adaptation to Chinese organizational cultures. The content validity index of the scale was 0.98. Principal components analysis resulted in a seven-factor model, accounting for 62% of total variance, with Cronbach's alphas for subscales ranging from 0.71 to 0.88. Known-group validity was established in the assessment results of the participants in permanent employment vs. contract employment (t = 2.895, p < 0.01). Good test-retest reliability was observed (r = 0.88, p < 0.01). Conclusion: The translated Chinese version of the WRQOLS-2 has sufficient validity and reliability so that it can be used to evaluate the QWL among nurses in mainland China.

Mandibular arch orthodontic treatment stability using passive self-ligating and conventional systems in adults: A randomized controlled trial

  • Rahman, Norma Ab;Wey, Mang Chek;Othman, Siti Adibah
    • The korean journal of orthodontics
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    • v.47 no.1
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    • pp.11-20
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    • 2017
  • Objective: This randomized controlled trial aimed to compare the stability of mandibular arch orthodontic treatment outcomes between passive self-ligating and conventional systems during 6 months of retention. Methods: Forty-seven orthodontic patients with mild to moderate crowding malocclusions not requiring extraction were recruited based on inclusion criteria. Patients (mean age $21.58{\pm}2.94years$) were randomized into two groups to receive either passive self-ligating ($Damon^{(R)}$ 3MX, n = 23) or conventional system (Gemini MBT, n = 24) orthodontic treatment. Direct measurements of the final sample comprising 20 study models per group were performed using a digital caliper at the debonding stage, and 1 month, 3 months, and 6 months after debonding. Paired t-test, independent t-test, and non-parametric test were used for statistical analysis. Results: A significant increase (p < 0.01) in incisor irregularity was observed in both self-ligating and conventional system groups. A significant reduction (p < 0.01) in second interpremolar width was observed in both groups. Mandibular arch length decreased significantly (p = 0.001) in the conventional system group but not in the self-ligating system group. A similar pattern of stability was observed for intercanine width, first interpremolar width, intermolar width, and arch depth throughout the 6-month retention period after debonding. Comparison of incisor irregularity and arch dimension changes between self-ligating system and conventional system groups during the 6 months were non-significant. Conclusions: The stability of treatment outcomes for mild to moderate crowding malocclusions was similar between the self-ligating system and conventional system during the first 6 months of retention.

A Convergence Study on the Demographic Differences in Technostressors (테크노 스트레스 유발 요인의 인구통계학적 차이에 관한 융복합 연구)

  • Yim, Myung-Seong
    • Journal of the Korea Convergence Society
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    • v.8 no.3
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    • pp.1-13
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    • 2017
  • The aim of this study is to investigate the demographical differences in technostressors(cause technological stresses). Although previous studies have been conducted to investigate the factors that affect technostress, little studies have examined the differences in demographic factors. Therefore, this study empirically attempts to investigate how level of technostressors differ by demographic factors. Independent sample t-test was used to identify differences after dividing sample into two groups. The technostressors used in this work are work overload, life invasion, complexity of technology, job insecurity, pace of technological change. We found that, sex and position show a significant difference in pace of technological change. In the educational level, there is a difference between work overload. Work overload, life invasion, complexity of technology, and pace of change show differences in age group. In computer knowledge, there are differences in complexity technology, job insecurity, and pace of change. On the other hand, there is no difference in computer using hours. Conclusions and implications are discussed in final section.