• Bulletin of the Korean Chemical Society
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• v.29 no.8
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• pp.1539-1544
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• 2008

A polymeric micelle, based on the poly(benzyl-L-histidine)-b-poly(ethylene glycol) (polyBz-His-b-PEG) diblock copolymer, was designed as a tumor-specific targeting carrier. The micelles (particle size: 67-80 nm, critical micelle concentration (CMC); 2-3 $\mu$g/mL) were formed from the diafilteration method at pH 7.4, as a result of self-assembly of the polyBz-His block at the core and PEG block on the shell. Removing benzyl (Bz) group from polyBz-His block provided pH-sensitivity of the micellar core; the micelles were physically destabilized in the pH range of pH 7.4-5.5, depending on the content of the His group free from Bz group. The ionization of His group at a slightly acidic pH promoted the deformation of the interior core. These pHdependent physical changes of the micelles provide the mechanism for pH-triggering anticancer drug (e.g., doxorubicin: DOX) release from the micelle in response to the tumor’s extracellular pH range (pH 7.2-6.5).

• Land and Housing Review
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• v.8 no.1
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• pp.13-22
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• 2017

In this study, triggering mechanism of ground sinking was analyzed through groundwater flow analysis on the basis of a case of the ground sinking occurred in Yongsan in 2015. The results of geotechnical investigation performed before and after the ground sinking were analyzed for the accurate understanding of geological features in the study area. The numerical groundwater flow analysis was performed to evaluate the influence of the flow behavior from the surrounding area toward the excavated site using software of Visual MODFLOW. As a result, it was found from the geotechnical analysis that the strata of sedimentary layer along the sunken area in the vertical direction was mixed significantly after the ground sinking compared with the status of the soil condition before the ground sinking. Piping was occurred at the toe of cut-off wall in the sandy gravel layer, and this phenomenon was predicted by the numerical flow analysis. Sequential ground displacement scenario of the ground sinking was derived from the geotechnical in situ test and numerical flow analysis performed in this study.

• Ocean and Polar Research
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• v.22 no.2
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• pp.57-67
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• 2000

Time-selective self-triggering water sampler, AUTTLE developed by Jin et al. (1999) has been improved in order to prevent pre-deposition of suspended sediments (SS) before sampling. By using two solenoids, the improved sampler is able to be moored or deployed with inclination. Its position is changed to horizontal position by activating the first solenoid, and then the endcaps of the sampling bottle are closed by the second solenoid that is driven three times to minimize possible failure of sampling. An external control unit for setting sampling time has been also constructed. Additionally, the electric circuit housing of the sampler has been modified to be detached from the sampling bottle when operating manually. Its performance has been confirmed through flume tests and a field experiment. It will serve as a valuable tool in the various fields of oceanography and environmental engineering, especially where seawater sampling synchronized at several sites and/or the information in storm period is important.

• Journal of the Korean Geotechnical Society
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• v.31 no.5
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• pp.47-58
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• 2015

Triggering rainfall and geologic conditions with the state of slope hazard were investigated based on the field investigation and collected data on the slope hazard during the period between 2011 and 2014 in Korea. Analysis results showed that most of slope hazards occurred in metamorphic rock and debris flow was the most frequent type of slope hazard. Slope hazard increased when the higher monthly mean rainfall was recorded. However, most of slope hazard occurred when certain time elapsed after the moment of maximum hourly rainfall. Finally, more than one month of long-term rainfall was shown to be related to the frequency of slope hazard in the period.

• Proceedings of the Korean Geotechical Society Conference
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• 2005.03a
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• pp.185-190
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• 2005

In this study, a probabilistic prediction model for debris flow occurrence was developed using a logistic regression analysis. The model can be applicable to metamorphic rocks and granite area. In order to develop the prediction model, detailed field survey and laboratory soil tests were conducted both in the northern and the southern Gyeonggi province and in Sangju, Gyeongbuk province, Korea. The six landslide triggering factors were selected by a logistic regression analysis as well as several basic statistical analyses. The six factors consist of two topographic factors and four geological and geotechnical factors. The model assigns a weight value to each selected factor. The verification results reveal that the model has 86.5% of prediction accuracy. Therefore, it is possible to predict landslide occurrence in a probabilistic and quantitative manner.

• Journal of the korean society of oceanography
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• v.34 no.4
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• pp.200-206
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• 1999

Seawater sampling is the primary task for the study of the marine environmental parameters that require shipboard or laboratory experiments for their analyses, and is also required for the calibration of some instruments for in situ measurement. A new automatic bottle (AUTTLE) is developed for seawater sampling at any desired time and water depth by self-triggering. Both any type of single or assembled mooring for 15 days and manual actuation by using a remote messenger as existing instantaneous single point water samplers are possible. Its sampling capacity and the resolution of time setting are 2 liters and 1 second, respectively. The result of a field experiment with an optical backscattering sensor (OBS) and a total of 14 AUTTLES for the in situ calibration of the OBS shows that the AUTTLE must improve our understanding on the behavior of the sand/mud mixtures in the environments with high waves and strong tides. The AUTTLE will serve as a valuable instrument in the various fields of oceanography, especially where synchronized seawater sampling at several sites is required and/or the information in storm period is important.

• Archives of Reconstructive Microsurgery
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• v.23 no.1
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• pp.29-32
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• 2014

Few articles have been written about the flexor tendon sheath ganglion in the finger, especially, between A1 pulley and A2 pulley. We report on rare cases of flexor tendon sheath ganglion with one symptomatic and two asymptomatic. All masses were evaluated using real-time ultrasonography and well-defined anechoic cystic lesions with posterior enhancement were observed. A 17-year-old female had a small mass at the 4th metacarpophalageal joint of her right hand, with pain and triggering. The patient underwent simple excision and a ganglion measuring $1.0{\times}0.8$ cm in size was derived from Camper's chiasm, between A1 pulley and A2 pulley. In two asymptomatic cases, ganglia measuring less than 0.5 cm in size observed. Based on our experience, real-time ultrasonography would be an excellent diagnostic modality in determining the treatment method in flexor tendon sheath ganglia, and surgical excision is recommended in symptomatic, especially triggering patients.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.57 no.2
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• pp.155-163
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• 2008

This paper presents a novel framework for analysis of power system wide-area blackout based on so called fault cascading scenarios. For a given power system operating state, "triggering" faults or a "seed faults" are chosen based on the probabilities estimated from the hazard rates. The fault probabilities reflect both the load and the weather conditions. Effects of hidden failures in protection systems are also reflected in establishing the fault propagation scenarios since they are one of the major causes for the wide-area blackouts. A tree type data structure called a PS-BEST(Power System Blackout Event Scenario Tree) is proposed for construction of the fault cascading scenarios, in which nodes represent various power system operating states and the arcs are the events causing transitions between the states. Arcs can be either probabilistic or deterministic. For a given initial fault, the total probability of leading to wide-area blackout is estimated by aggregating the individual probability of each fault sequence route leading to wide-area blackout. A case study is performed on the IEEE RTS-79(24 bus) system based on the fault data presented by the North American Electrical Reliability Council(NERC). Test results demonstrate the potentials and the effectiveness of the proposed technique for the future wide-area blackout analysis.

• Proceedings of the Botanical Society of Korea Conference
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• 1996.07a
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• pp.10-18
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• 1996

Recently, we have reported a rice MADS-box gene, OsMADS1, as a molecular factor triggering flower formation; this has been well studied in a heterologous system (Chung et al., 1994). In order to study whether the OsMADS1 homolog exists in other plant species, the OsMADS1 cDNA was used as a probe to screen a tobacco cDNA library, and a potential homolog, NtMADS3, was isolated. Sequence analysis revealed that the gene shares 56.1% identity in whole amino acids with OsMADS1. Like OsMADS1, the NtMADS3 gene starts to express at a very early stage of flower development, and the expression continues up to flower maturation. In the tobacco flower, the gene is expressed in whorl 2,3 and 4, corresponding to the petal, stamen, and carpel, respectively. Upon ectopic expression in the homologous system, NtMADS3 caused a trasition from inflorescence shoot meristem into floral meristem, reducing flowering time dramatically. These phenotypes strongly suggest the NtMADS3 gene is the OsMADS1 homolog of tobacco. Hybrids between the OsMADS1 and the NtMADS3 plants were also generated. The hybrids flowered even earlier than these two transgenic plants. The detailed studies are discussed here.

• KIEE International Transactions on Electrophysics and Applications
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• v.5C no.4
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• pp.145-151
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• 2005

The synthetic breaking test method was developed to evaluate the breaking performance of ultra high-voltage circuit breaker and made up of two independent circuits; current source circuit and voltage source circuit. In application of this test method, it is necessary to extend the arc of the test breaker. So, the new re-ignition system using VTGS (Vacuum Triggered Gap-Switch) was constructed to improve the efficiency and reliability of this test. In this re-ignition system, VTGS operates in high vacuum state of $5{\time}10^{17}$torr and control system consists of the triggering device and the air M-G (Motor-Generator). This re-ignition system showed the operating characteristics, such as delay time ($t_d$) and jitter time ($t_j$ not exceeding 5us and 1us respectively, and had the operating voltage of $25\~150kVdc$ at the gap distance of 24mm.