• Title/Summary/Keyword: trial test

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Hydrodynamic Evaluation for Developing the New Inflatable Kayak (신형 인플래터블 카약 개발을 위한 유체역학적 성능평가)

  • Hah, Chong-Ku;Kim, Ho;Lim, Lee-Young;Ki, Jae-Suk
    • Journal of Advanced Marine Engineering and Technology
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    • v.39 no.3
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    • pp.334-341
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    • 2015
  • This study is to evaluate hydrodynamic performance evaluation between three kinds of inflatable kayaks, that is, a frame kayak, a needle knife kayak, and a v-hull kayak. In order to test, inclining and turning trial test are performed in the Ocean Engineering Basin. Also, a resistance test is performed with a reduced scale kayak in the circulating water channel. Consequently, First, the moment arm of a v-hull kayak is the largest with 132.4mm, but turning radius of one was the smallest of them. Second, the resistance of a needle knife kayak is the smallest with 71N, the center of gravity of one was the lowest with 0.128m of them, and then needle knife kayak occurs in a draft overall. Consequently, the v-hull kayak has had the advantages on restoring force and turning performance than others. The needle knife kayak has been more excellent on resistance and center of gravity than others.

Suppression and Recognition Reading Span Test (억제와 재인 읽기폭 검사)

  • 이병택;이경민;김정오;홍재성
    • Korean Journal of Cognitive Science
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    • v.13 no.4
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    • pp.91-98
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    • 2002
  • The aim of this study is to make the recall-based reading span test(Daneman & Carpenter, 1980) into the recognition-based test for on-line measuring the capacity of the participant. In order to measure the concurrent validity, a series of experiments is performed with varying features of distractors consisting of the reading span test. In experiment 1, which included irrelevant words as distractor, low correlation was observed. And in experiment 2, including several types of distractors which interfere with the selection of target words, low correlation was observed too. But in experiment 3, including distractors no more relevant in the Present trial but relevant in previous trial, high correlation was observed. The results of this study have theoretical implications on the validity of the reading span test and practical implication in that this study provides the tool for the studies on individual differences in working memory capacity.

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Pooled Analysis of the Cow's Milk-related-Symptom-Score (CoMiSSTM) as a Predictor for Cow's Milk Related Symptoms

  • Vandenplas, Yvan;Steenhout, Philippe;Jarvi, Anette;Garreau, Anne-Sophie;Mukherjee, Rajat
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.20 no.1
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    • pp.22-26
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    • 2017
  • Purpose: The diagnosis of cow's milk (CM) allergy is a challenge. The Cow's Milk-related-Symptom-Score ($CoMiSS^{TM}$) was developed to offer primary health care providers a reliable diagnostic tool for CM related symptoms. The predictive prospective value of the $CoMiSS^{TM}$ was evaluated in three clinical trials. Methods: Pooled analyses of the three studies were conducted based on regressing the results of the month-1 challenge test on the month-1 $CoMiSS^{TM}$, adjusting for baseline $CoMiSS^{TM}$ using a logistic regression model. In addition a logistic regression model was also fitted to the month-1 challenge test result with the change in $CoMiSS^{TM}$ from baseline as a predictor. Results: Results suggest that infants having a low $CoMiSS^{TM}$ (median, 5) after 1 month dietary treatment free from intact CM protein have a significant risk of having a positive challenge test (odds ratio, 0.83; 95% confidence interval, 0.75-0.93; p=0.002). Pooled data suggest that the change in $CoMiSS^{TM}$ from baseline to month-1 can predict CM related symptoms as a confirmed diagnosis according to the challenge test at month-1. However, in order to validate such a tool, infants without CM related symptoms would also need to be enrolled in a validation trial. A concern is that it may not be ethical to expose healthy infants to a therapeutic formula and a challenge test. Conclusion: Pooled data analysis emphasizes that the $CoMiSS^{TM}$ has the potential to be of interest in infants suspected to have CM-related-symptoms. A prospective validation trial is needed.

Effects of Korean Red Ginseng on Cognitive and Motor Function: A Double-blind, Randomized, Placebo-controlled Trial

  • Yeo, Hye-Bin;Yoon, Ho-Kyoung;Lee, Heon-Jeong;Kang, Seung-Gul;Jung, Ki-Young;Kim, Leen
    • Journal of Ginseng Research
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    • v.36 no.2
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    • pp.190-197
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    • 2012
  • Ginseng has a long history of use for health enhancement, and there is some evidence from animal studies that it has a beneficial effect on cognitive performance. The purpose of this study was to investigate the effect of Korean red ginseng on cognitive performance in humans. A total of 15 healthy young males with no psychiatric or cognitive problems were selected based on an interview with a board-certified psychiatrist. The subjects were randomly assigned to receive a daily dose of 4,500 mg red ginseng or placebo for a 2-week trial. There were 8 subjects in the red ginseng group and 7 subjects in the placebo group. All of the subjects were analyzed with the Vienna test system and a P300 event-related potential (ERP) test. There were no significant differences in the Vienna test system scores between the red ginseng group and the placebo group. In the event-related potential test, the C3 latency of the red ginseng group tended to decrease during the study period (p=0.005). After 2 wk, significant decreases were observed in the P300 latencies at Cz (p=0.008), C3 (p=0.005), C4 (p=0.002), and C mean (p=0.003) in the red ginseng group. Our results suggest that the decreased latency in ERP is associated with improved cognitive function. Further studies with a higher dosage of ginseng, a larger sample size, and a longer follow-up period are necessary to confirm the clinical efficacy of Korean red ginseng.

Evaluation of the Effectiveness and Safety of Zanthoxylum piperitum Leaf Extract against Mild Degenerative Osteoarthritis of Knee: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial (경증의 퇴행성 슬관절염에 대한 초피나무잎 추출물의 유효성 및 안전성 평가: 무작위 배정, 이중맹검, 위약대조 임상연구)

  • Jeong, Ji-Hong;Lee, Soo-Hwan;Yoon, Hong-Ryoul;Kim, Soon-Joong
    • Journal of Korean Medicine Rehabilitation
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    • v.31 no.4
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    • pp.167-191
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    • 2021
  • Objectives Degenerative osteoarthritis of knee is a disease with an increasing number of patients worldwide and its general treatments have some side effects. Methods 102 subjects were classified into test group 1, test group 2, and control group, and clinical trial products were taken for 12 weeks. The effectiveness was evaluated with changes in visual analogue scale, Korean-Western Ontario and McMaster Universities Osteoarthritis Index, inducible nitric oxide synthase, and cyclooxygenase-2. Results Both test group 1 and test group 2 were effective in reducing the pain of degenerative osteoarthritis of knee, and only test group 2 was effective in improving the ability to perform daily activities. No clinically significant changes were observed for any safety parameter. Conclusions In conclusion, the data of this study indicate that Zanthoxylum piperitum leaf extract has effectiveness and safety against mild degenerative osteoarthritis of knee.

A Randomized trial to investigate the effect of Asparagus racemosus root tablet in Relieving Postmenopausal Hot Flashes

  • K.M. Hina Fatima;Mariyam Roqaiya;Nawazisha
    • CELLMED
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    • v.14 no.10
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    • pp.10.1-10.6
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    • 2024
  • Background and Objectives: As per the available data, 75% peri and postmenopausal women experience hot flashes having negative effect on their quality of life. Using herbal medicines are stepping forward to alleviate hot flashes as the available hormonal medications have been reported the presence of side effects. This study was planned with the intention to investigate the effect of Asparagus racemosus root in the treatment of postmenopausal hot flashes in comparison to the placebo. Methods: This prospective patient blinded clinical trial randomly assigned 40 postmenopausal women with symptoms of hot flashes to receive either test drug (n=20) comprising Asparagus racemosus tablet of 1g in the dosage of 2 tablet thrice in a day for the duration of 60 days continuously or to receive placebo tablet prepared from roasted wheat flour in the same dosage and duration as test drug. The efficacy was determined by reduction in the frequency and intensity of hot flashes assessed by daily diary along with the improvement in quality of life assessed through Hot Flash-Related Daily Interference Scale. Statistical analysis was accomplished by student t test and Chi-square/Fisher Exact test. Results: Test drug significantly (p <0.001) reduced the intensity and frequency of hot flashes as well as improved the quality of life without showing any side effect. Discussion & Conclusion: According to Unani scriptures, the treatment is to treat the underlying cause, such as aberrant temperament and psychological and environmental issues. Unani drugs have emmenagogue, anti-inflammatory, analgesic, and neuroprotective qualities that can help alleviate premenstrual symptoms. Unani herbs such as C. sativus, Vitex, agnus castus, P. vulgare, N. Jatamansi, M. officinalis, and Z. officinalis have been clinically demonstrated to be effective in PMS. Thus, traditional knowledge authentication and conservation are vital for future research and appreciated for application in the modern day. Furthermore, randomised controlled trials, comprehensive reviews, and meta-analyses are suggested.

Analysis of IP Subnet Allocation Method for Access Network in a Broadband Trial Network (초고속시범망 엑세스 네트워크의 IP 서브넷 할당방식 분석)

  • 이운영;임병학오채형이정수
    • Proceedings of the IEEK Conference
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    • 1998.10a
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    • pp.11-14
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    • 1998
  • Recently, the users of internet are increasing yearly with the rapid spread of internet. So, the shortage of IPv4 address is important issue to ISP. Many ISP is searching for efficient method to use IP address in ATM Network. Korea Telecom has constructed ATM Network test-bed to verify available technologies necessary for ATM Network. This paper, concerning with the configuration of subscribers in ATM Network test bed, analyze the available usage of IP address.

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Likelihood Ratio Test for the Equality of Two Order Restricted Normal Mean Vectors

  • Jeon Hyojin;Choi Sungsub
    • Proceedings of the Korean Statistical Society Conference
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    • 2000.11a
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    • pp.159-164
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    • 2000
  • In the study of the isotonic regression problem, several procedures for testing the homogeneity of a normal mean vector versus order restricted alternatives have been proposed since Barlow's trial(1972). In this paper, we consider the problem of testing the equality of two order restricted normal mean vectors based on the likelihood ratio principle.

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Study on the performance verification of IEC 61850 communication service on domestic IEDs (국내 IED 시작품대상 IEC 61850 통신서비스 성능 검증에 관한 연구)

  • Lee, N.H;Jang, B.T.
    • Proceedings of the KIEE Conference
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    • 2008.11a
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    • pp.3-5
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    • 2008
  • Korea Electric Power Research Institute has being carried out an IEC 61580 based communication service test on domestic IED trial products developed related to power IT project. This paper describes IEC 61850-10 conformance test and testing items established by UCA international Users Group and this study is on the analysis of testing results from IED communication service with selected testing blocks, which consist of Basic association, Dataset, Reporting and GOOSE.

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Heteroscedasticity of Random Effects in Crossover Design

  • Ahn, Chul-H.
    • Proceedings of the Korean Statistical Society Conference
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    • 2002.11a
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    • pp.79-83
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    • 2002
  • A phase III clinical trial of a new drug for neutropenia induced by chemotherapy is presented and consider adding random effects in crossover design which was used in the clinical study. The diagnostics for its heteroscedasticity based on score statistic is derived for detecting homoscedasticity of errors in crossover design. A small simulation study is peformed to investigate the finite sample behaviour of the test statistic which is known to have an asymptotic chi-square distribution under the null hypothesis.

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