It has well reported that tumor markers have many advantages like minimally invasive, convenient use, low cost but also has many limitations like low sensitivity and specificity, relevance of prognosis, low organ specificity. Although no tumor markers are ideal, many tumor markers are used for cancer diagnosis, treatment monitoring, and surveillance monitoring after treatment. We review the classification and characteristics of tumor markers according cancer types and clinical roles in current times.
Journal of the Korean Institute of Landscape Architecture
/
v.40
no.2
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pp.97-111
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2012
This study aims to find a proper construction cost calculation method by comparing unit prices of cost estimate in landscape construction among other public ordering construction projects. There were 7 out of 12 items from the actual work cost in the first half of 2011 were compared. The 12 items were classified as landscape Architectural construction and the 7 items were the approximate standard. As applied construction types, the comparable 35 items out of the 80 actual work cost items applied to 5 sites were compared to the unit price of the standard quantity per unit in March 2011, which was the approximate standard. Actual construction rate of the 7 items in the category of landscape sector was 104.86% for each item and 92.09% as a total construction cost. The high actual construction rate was caused by the high rate of seed spray depending on the status of applying rocks. However, there were more fundamental reasons for the cost generated from aslope treatment for grass and seed spray. So, it requires more detailed regulations on the modification factors for each soil type, the standard and needs to improve theillogical standard quantity per unit system. Actual construction rate of the 35 items in the applied sectors of civil engineering and architecture was 78.65% for each item and 71.31% (70.17%) as a total construction cost. This shows that actual unit cost cannot reflect actual cost structurally and standard quantity per unit system lacks practicality in terms of construction due to thelabor force. 85.1~91.2 % actual construction rate announced by the Ministry of Land and Maritime Affairs referred to the newly switched items. So the result was estimated as actual construction rate. This requires supplementation after verification in order to make the actual work cost produce at a proper rate. Also, standard quantity per unit system needs complementation with these actual data and so on.
The purpose of this study was to investigate applicability of pretreatment on the existing biological treatment for domestic wastewater reclamation. From Jar Tests, it was found that optimum dosage of coagulant was PAC 0.5mg/L and $FeCl_3$ 180mg/L for urban sewage. In this study, PAC 0.5mg/L was selected considering sludge production and the amount of coagulant required. In a continuous experiment performed with combining chemical coagulation and biological treatment, a considerable removal efficency was obtained in term of BOD, SS, T-N, T-P and ABS. When the raw sewage was supplied into the pre-chamical treatment facility, the removal of BOD and SS was 48.3% and 81.1%. However T-N removal was very low which means T-N consists of $NH_3-N$ mostly. T-P was almost completely recluced by the chemical addition. The effluent BOD & SS was 57~76 and 21~43mg/L, which could reduce the size of biological treatment facility. From the cost estimation pre-chemical treatment could save around half of the area required for biological treatment with post ceagulation.
Journal of The Korean Society of Grassland and Forage Science
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v.13
no.3
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pp.228-233
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1993
Method for the sun curing dehydration of pig excreta by using vinyl house was described. We determined effects of the dehydrated pig excreta on the yields of whole crop corn and proximate chemical composition of whole crop corn. Pig excreta were dehydrated upto 15% of moisture content by the 3-4 days of sun curing dehydration in vinyl house in the summer period. There was no significant difference between the dehydrated pig excreta treatment and the chemical fertilizer treatment on dry matter(DM) content, DM yield and crude protein contents of whole crop corn. Ca and Mg contents by the dehydrated pig excreta treatment were lower than those by thechemical fertilizer treatment. In the contrast, K content by the dehydrated pig excreta treatment was higher than those by the chemical fertilizer treatment. and dehydrated pig excreta treatments were higher in K/Ca+Mg ratio than chemical fertilizer treatment. These results suggested the availability of the sun curing dehydration of pig excreta in vinyl house in small-scale animal industry. In addition, the dehydrated pig excreta treatment showen similar effects to the chemical fertilizer treatment on dry matter yields and contents of chemical composition of whole crop corn. These results suggest that using the sun curing dehydration of pig excreta could reduce the chemical fertilizer cost. However, we need more study to the relationship between the unbalanced mineral contents and animal health.
Purpose: By investigating oral health knowledge and oral health behavior of orthodontic patients, we intend to identify factors that affect their satisfaction with orthodontic treatment and use them as fundamental data for improving the satisfaction of orthodontic patients. Methods: Busan from February 1st to March 31st, 2021. Dental disease in Gyeongsangnam-do. A self-contained survey was conducted on patients undergoing orthodontic treatment in the clinic. A total of 185 copies were analyzed. Using the lBM SPSS Statistics 21 program, multiple regression analysis was conducted by setting oral health knowledge and oral health behavior as independent variables to determine factors affecting remedial treatment satisfaction. Results: The satisfaction level of orthodontic treatment was 1.53 points higher than 'understanding the cost of orthodontic treatment' and 'smooth relationship with related staff while receiving orthodontic treatment' was low at 1.23. The average calibration satisfaction was 1.34. Factors affecting remedial treatment satisfaction were shown in the order of oral health behavior (p<0.000), educational experience (p<0.010), gender (p<0.015) and oral health knowledge (p<0.020). Conclusions: Through the above results, it is necessary to develop programs to improve oral health knowledge through customized individual oral health education by enhancing individual oral health behaviors of individuals.
Journal of the Korea Society of Computer and Information
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v.23
no.12
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pp.171-177
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2018
Purpose : This study is conducted to research the attitude of social workers toward withdrawing life sustaining treatment and compare and analyze the different types of their attitudes. Methods : Research design of this study is Q methodology approach. The study population is 23 social workers. Q sample to investigate the attitude of social workers toward withdrawing life sustaining treatment included 30 statements. After listening to the purpose and method of the study, the 23 social workers agreed to fill out a survey asking sociodemographic information and have been forced to be distributed in 9 scale Q-sample. Results : The collected data was processed through QUANL PC program, sorted into 3 types as followings. The first type was 'the pursuit of quality of life' that the quality of life is more important than the length of life, the second 'choosing to withdraw life sustaining treatment' that they want to write or encourage family to write advanced directive, the third 'withholding life sustaining treatment' regardless of the cost. Conclusion : In conclusion, the social workers attitudes toward withdrawing life sustaining treatment were grouped as three different types, the first type was 'the pursuit of quality of life', the second 'choosing to withdraw life sustaining treatment', the third 'withholding life sustaining treatment'.
Objectives: Since 1991, nationwide massive neonatal screening program for phenylketonuria (PKU) and congenital hypothyroidism have been performed in Korea. As in many other countries, efficiency of this program has not been definitely concluded. For the purpose of evaluation of this program, from the perspective of efficiency, a cost-benefit analysis was carried out. Methods: Costs of the detection and the treatment program were compared with the projected benefit(avoided costs) that results from the prevention of the mental retardation associated with the disorders due to PKU and hypothyroidism. Costs and benefits were discounted at an annual rate of 5%, and duration of life-long labor was assumed to be 30 years. Cost and benefit were estimated based on the detection rates of one case of PKU per 5,572 and one case of congenital hypothyroidism per 32,554 babies screened during 1991-1997. Results: The benefit-cost ratio was 0.418. The sensitivity analysis for the discount rates and labor durations showed that most cost-benefit ratios were lower than one(1.0) except when discount rate was changed to 3% and detection rate to two- or threefold and/or labor duration to 40 years. Conclusion: The result of this study suggested that present program of mass screening for PKU and congenital hypothyroidism could not be justified in terms of efficiency. It doesn't coincide with the results of previous studies in major developed countries, presumably because of difference in detection rates and welfare cost for the disabled.
Park, Soon-Dong;Kim, Kwang-Mo;Jun, Byung-Hyuk;Han, Young-Hee;Kim, Chan-Joong
Progress in Superconductivity
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v.13
no.2
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pp.133-138
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2011
To reduce the processing cost of the single grain REBCO (RE: Rare-earth elements) bulk superconductors, a cost-effective process should be developed. One possible way of developing the cost-effective process is the use of low-cost precursor powders. In this study, the single grain YBCO superconductors were fabricated using a home made powder. $YBa_2Cu_3O_{7-y}$ (Y123) powders were synthesized at $850-900^{\circ}C$ in air by the powder calcination method with repeated crushing and heat treatment steps. The processing parameters for the fabrication of single grain Y123 bulk superconductors, $T_{max}$ (maximum temperature), $T_p$ (peritectic temperature) and a cooling rate through $T_p$ were optimized. To enhance the flux pinning capacity of the single grain Y123 samples, $Y_2BaCuO_5$ (Y211) particles were dispersed in the Y123 matrix by adding $Y_2O_3$ powder to the calcined Y123 powder. Applying the optimized processing condition, the single grain Y123 superconductors with $T_c=91\;K$ and $J_c=1.5{\times}10^4\;A/cm^2$ at 2 T were successfully fabricated using a home made powder. The levitation forces and trapped magnetic field at 77 K measured using a Nd-B-Fe permanent magnet of 5300 G were 47 N and 3000 G, respectively, which are comparable to those obtained for the samples fabricated using a commercial grade Y123 powders.
Background: To determine the outcome and cost saving by placing ultrasound guided surgical clips for tumor localization in patients undergoing neo-adjuvant chemotherapy for breast cancer. Materials and Methods: This retrospective cross sectional analytical study was conducted at the Department of Diagnostic Radiology, Aga Khan University Hospital, Karachi, Pakistan from January to December 2014. A sample of 25 women fulfilling our selection criteria was taken. All patients came to our department for ultrasound guided core biopsy of suspicious breast lesions and clip placement in the index lesion prior to neo-adjuvant chemotherapy. All the selected patients had biopsy proven breast cancer. Results: The mean age was $45{\pm}11.6years$. There were no complications seen after clip placement in terms of clip migration or hemorrhage. The cost of commercially available markers was approximately PKR 9,000 (US$ 90) and that of the surgical clip was PKR 900 (US$ 9). The cost of surgical clips in 25 patients was PKR 22,500 (US$ 225), when compared to the commercially available markers which may have incurred a cost of PKR 225,000 (US$ 2,250). The total cost saving for 25 patients was PKR 202,500 (US$ 2, 025), making it PKR 8100 (US$ 81) per patient. Conclusions: The results of our study show that ultrasound guided surgical clip placement in index lesions prior to neo-adjuvant therapy is a safe and cost effective method to identify tumor bed and response to treatment for further management.
Purpose: This study aimed to evaluate the profitability of four selective mechanization systems in rice cultivation. Methods: Field experiments were conducted in the farmers' field during the wet season (June to November) of 2015 in Bangladesh. Mechanization systems were applied to evaluate four different selective levels (treatment) in eleven consequent operations. Seedlings were raised in a traditional seedbed and trays for manual and mechanical transplanting, respectively. Land preparation, irrigation, fertilizer, pesticide, carrying, and threshing and cleaning operations were performed using the same method in all the experimental plots. The mechanical options in the transplanting, weeding, and harvesting operations were changed. The mechanization systems were $S_1$ = hand transplanting + hand weeding + harvesting by sickle, $S_2$ = mechanical transplanting + Bangladesh Rice Research Institute (BRRI) weeder + reaper, $S_3$ = mechanical transplanting + BRRI power weeder + reaper, and $S_4$ = mechanical transplanting + herbicide + reaper. This experiment was performed in a randomized complete block design with four replications. Power tiller, rice transplanter, BRRI weeder, BRRI power weeder, self-propelled reaper, BRRI open drum thresher, and BRRI winnower were used in the respective operations. Accordingly, the techno-economic performances of the different technologies were calculated and compared with those of the traditional system. Results: The mechanically transplanted plot produced 6-10% more yield than the hand transplanted plot because of the use of tender-aged seedlings. Mechanical transplanting reduced 61% labor and 18% cost compared to manual transplanting. The BRRI weeder, BRRI power weeder, and herbicide application reduced 74, 91, and 98% labor, respectively. The latter also saved 72, 63, and 82% cost, respectively, compared to hand weeding. Herbicide application reduced the substantial amount of labor and cost in the weeding operation. Mechanical harvesting also saved 96% labor and 72% cost compared to the traditional method of harvesting using sickle. Selective mechanization saved 15-17% input cost compared to the traditional method of rice cultivation. Conclusions: Mechanical transplanting with the safe use of herbicide and harvesting by reaper is the most cost- and labor-saving operation. The method might be the recommended set of selective mechanization for enhancing productivity.
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