• The Korean Journal of Physiology and Pharmacology
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• v.8 no.3
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• pp.117-127
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• 2004

The heterodimeric amino acid transporter family is a subfamily of SLC7 solute transporter family which includes 14-transmembrane cationic amino acid transporters and 12-transmembrane heterodimeric amino acid transporters. The members of heterodimeric amino acid transporter family are linked via a disulfide bond to single membrane spanning glycoproteins such as 4F2hc (4F2 heavy chain) and rBAT $(related\;to\;b^0,\;^+-amino\;acid\;transporter)$. Six members are associated with 4F2hc and one is linked to rBAT. Two additional members were identified as ones associated with unknown heavy chains. The members of heterodimeric amino acid transporter family exhibit diverse substrate selectivity and are expressed in variety of tissues. They play variety of physiological roles including epithelial transport of amino acids as well as the roles to provide cells in general with amino acids for cellular nutrition. The dysfunction or hyperfunction of the members of the heterodimeric amino acid transporter family are involved in some diseases and pathologic conditions. The genetic defects of the renal and intestinal transporters $b^{0,+}AT/BAT1\;(b^{0,+}-type\;amino\;acid\;transporter/b^{0,+}-type\;amino\;acid\;transporter\;1)$ and $y^+LAT1\;(y^+L-type\;amino\;acid\;transporter\;1)$ result in the amino aciduria with sever clinical symptoms such as cystinuria and lysin uric protein intolerance, respectively. LAT1 is proposed to be involved in the progression of malignant tumor. xCT (x-C-type transporter) functions to protect cells against oxidative stress, while its over-function may be damaging neurons leading to the exacerbation of brain damage after brain ischemia. Because of broad substrate selectivity, system L transporters such as LAT1 transport amino acid-related compounds including L-Dopa and function as a drug transporter. System L also interacts with some environmental toxins with amino acid-related structure such as cysteine-conjugated methylmercury. Therefore, these transporter would be candidates for drug targets based on new therapeutic strategies.

• Ocean Science Journal
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• v.42 no.2
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• pp.89-102
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• 2007

The surface circulation of northern South China Sea (hereafter SCS) for the period 1987-2005 was studied using the data of more than 500 satellite-tracked drifters and wind data from QuikSCAT. The mean flow directions in the northern SCS except the Luzon Strait (here after LS) during the periods October_March was southwestward, and $April{\sim}September$ northeastward. A strong northwestward intrusion of the Kuroshio through the LS appears during the $October{\sim}March$ period of northeasterly wind, but the intrusion became weak between April and September. When the strong intrusion occurred, the eddy kinetic energy (EKE) in the LS was $388cm^2/s^2$ which was almost 2 times higher than that during the weak-intrusion season. The volume transport of the Kuroshio in the east of the Philippines shows an inverse relationship to that of the LS. There is a six-month phase shift between the two seasonal phenomena. The volume transport in the east of the Philippines shows its peak sis-month earlier faster than that of the LS. The strong Kuroshio intrusion is found to be also related to the seasonal variation of the wind stress curl generated by the north easterly wind. The negative wind stress curl in the northern part of LS induces an anticyclonic flow, while the positive wind stress curl in the southern part of LS induces a cyclonic flow. The northwestward Kuroshio intrusion in the northern part of LS happened with larger negative wind stress curl, while the westward intrusion along $20.5^{\circ}N$ in the center of the LS occurred with weaker negative wind stress curl.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.21 no.4
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• pp.18-29
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• 2022

Since the operation of an reft-turn actuated signal driven mainly by vehicles may increase the waiting time for walking, this signal causes inconvenience or stress to pedestrians. Therefore, in this study, the change in waiting time for walking before and after the application of an reft-turn actuated signal and the stress on the pedestrians were investigated through a questionnaire. The investigation showed that the waiting time for walking increased by 37% during non-peak time. Also the waiting time for walking of 62.1% of pedestrians became longer and 78% of them were stressed because of it. Meanwhile, simulation(VISSIM) showed that the vehicle travel speed slightly decreased to 1.07km/h(a 2.5% decrease), and the average waiting time for walking decreased by 15.51sec(a 28% decrease) with a pedestrian priority actuated signal. Therefore, it is expected that the pedestrian priority actuated signal can reduce the waiting time for walking and relieve pedestrian stress.

• Water for future
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• v.18 no.3
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• pp.235-241
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• 1985

The predictions of the local and regional sand transport of the offshore tidal sand banks tn the west coast of Korea, east of the Yellow San have been performed on the basis of diagrammatical method suggested by Kenyon et al(1981). There is general agreements between these predictions and the earlier predictions(Choi, 1983) of net regional sand transport paths from the numerical simulation of maximum bottom stress vector during the semidiurnal period due to m2 and m4 tides. Further detailed investigations are proposed for the study of Choongang Chontoe where the predicted net sand transport direction is to the dredged navigation channel.

• Transactions on Electrical and Electronic Materials
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• v.16 no.3
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• pp.107-111
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• 2015

Our work is based on the development of a numerical model to develop a methodology for predicting the aging and breakdown in insulation due to the dynamics of space charge packets. The model of bipolar charge transports is proposed to simulate space charge dynamic for high DC voltage in law-density polyethylene (LDPE), taking into account the trapping and detrapping of recombination phenomena, this model has been developed and experimentally validation. Theoretical formulation of the physical problem is based on the Poisson, the continuity and the transport equations as well as on the appropriate models for injection. Numerical results provide temporal and local distributions of the electric field, the space charge density for the different kinds of charges, conduction and displacement current densities, and the external current.

• Journal of the Korean Society of Mechanical Technology
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• v.20 no.6
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• pp.830-835
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• 2018

The tubular link chain conveyor works under very extreme conditions such as high tensile load, friction, and dangerous operating environments. In this study, we propose an optimal design plan for reducing cost and improving performance through weight reduction of tubular link chain conveyors for sludge transport. For light weight of tubular link chain conveyor, the optimization software using SHERPA algorithms, HEEDS was used in conjunction with ANSYS Mechanical V14.5, which is widely used in structural analysis, to achieve optimal tubular link chain. Through the optimization process, 19% light weight was achieved.

• Transactions of the Korean Society of Pressure Vessels and Piping
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• v.18 no.2
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• pp.50-53
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• 2022

To investigate the validity of the finite element analysis program to assess structural integrity of a spent nuclear fuel transport cask subjected to extreme impact loads, structural integrity of the cask for the case of an aircraft engine collision is evaluated using three FE analysis programs: Autodyn, Speed and ABAQUS explicit version. As a result of all analyses, it is confirmed that no penetration occurred in the cask wall. Even though the different programs are used, it is identified that there are insignificant differences in the FE analysis variables such as von Mises effective stress and equivalent plastic strain among the programs.

• Journal of Applied Biological Chemistry
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• v.63 no.4
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• pp.347-355
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• 2020

Several sensors have been developed for soil and plants to assess plant stress due to climate change. Therefore, the objective of the study is to nondestructively evaluate temperature stress on plant by monitoring climatic and soil conditions and plant responses using various sensors. Plant responses were monitored by electrical conductivity in plant stem and sap flow rate. Electrical conductivity in plant stem reflects the physiological activity of plants including water and ion transport. Fully grown Brassica oleracea var. italica was exposed to 20/15 ℃ (day/night) with 16 h photoperiods as a control, low temperature 15/10 ℃, and high temperature 35/30 ℃ while climatic, soil, and plant conditions were monitored. Electrical conductivity in plant stem and sap flow rate increased during the day and decreased at night. Under low temperature stress, electrical conductivity in plant stem of Brassica oleracea var. italica was lower than control while under high temperature stress, it was higher than control indicating that water and ion transport was affected. However, chlorophyll a and b increased in leaves subjected to low temperature stress and there was no significant difference between high temperature stressed leaves and control. Free proline contents in the leaves did not increase under low temperature stress, but increased under high temperature stress. Proline synthesis in plant is a defense mechanism under environmental stress. Therefore, Brassica oleracea var. Italica appears to be more susceptible to high temperature stress than low temperature.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.26 no.5B
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• pp.529-537
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• 2006

This paper investigates the impacts of the drag-related weighting coefficients on mean velocity and turbulence structures. The transport equations for the Reynolds stress of vegetated open-channel flows are derived by using the temporal- and horizontal-averaging scheme. It is found that the total Reynolds stress of vegetated open channel flows consists of the Reynolds stress due to temporally fluctuating velocities and the Reynolds stress due to spatially fluctuating velocities. The drag-related weighting coefficient $C_{fk}$ for the total Reynolds stress component is found to be unit, while the coefficient for the Reynolds stress due to temporally fluctuating velocities can be negligible. This is the reason why very small weighting coefficients in previous studies yield very good agreements with measured data. In other words, the Reynolds stress due to spatially fluctuating velocities remains still unknown, especially due to the large number of measuring locations. Through a developed Reynolds stress model, vegetated open-channel flows are simulated and compared with measured data from the literature. Comparisons reveal that the computed mean flow and Reynolds stress structures are hardly affected by the drag-related weighting coefficients. However, the computed turbulence intensity profiles are significant different with the drag-related weighting coefficients. A budget analysis of the transport equations for the Reynolds stress component is carried to investigate why turbulence intensity is affected by the drag-related weighting coefficients.

• KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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• v.27 no.2
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• pp.109-114
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• 2021

The characteristics of vibrational stress (shock and vibration) during transport and the possibility of damage to the packaged pears by functional PLA tray were investigated. And this study was conducted to analyze how environmental conditions by simulated transport environment affect quality factors such as weight loss (%) and soluble solid content (SSC, %), and firmness (bioyield strength, kPa) of packaged pears by PLA tray and Expanded PET foam pad (Group 1), EPE cushion cup pad and net (Group 2) for exporting. Pears with or without vibration stress were stored for 30 days at low temperatures (5 ± 0.8℃, 80 ± 5% relative humidity). There was the statistically significant difference (p ≤ 0.05) between pears with and without vibration stress for weight loss, soluble solid content, and firmness (bioyield strength) after 30 days storage. Vibration stress accelerated pear quality deterioration during storage, resulting in increased weight loss, soluble solids content, and reduced hardness. The firmness (bioyield strength) and weight changes of pears with PLA trays were smaller than those of conventional packaging box systems. It was determined that the firmness of agricultural products was a quality factor closely related to the storage period and that PLA could be applied.