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A Study of the Reliability and Validity of Standard Tools for the Pattern Identification of Gastroesophageal Reflux Disease (위식도역류질환 변증도구의 신뢰도 및 타당도 평가)

  • Cho, Yun-jae;Ha, Na-Yeon;Ko, Seok-Jae;Park, Jae-Woo;Kim, Jinsung
    • The Journal of Internal Korean Medicine
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    • v.43 no.1
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    • pp.1-21
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    • 2022
  • Purpose: The standard tool for the pattern identification is used for identifying patterns in patients using a questionnaire. The purpose of this study is to reorganize the standard tool for the pattern identification of gastroesophageal reflux disease (GERD) developed in 2017 and to analyze the reliability and validity of the standard tool for pattern identification by applying it to GERD patients. Methods: To reorganize the standard tool for the pattern identification of GERD developed in the previous study, we searched the literature in the main databases, OASIS (Oriental Medicine Advanced Searching Integrated System) and CNKI (China National Knowledge Infrastructure). We added the search results to the data used in the previous study and went through the reorganizing courses, such as evaluating the validity of the translation, the Delphi technique, and a small survey. After reorganization, the patients who visited the Kyunghee University Korean Medicine Center for GERD symptoms were provided the questionnaire, including the reorganized standard tool for pattern identification. We analyzed the survey results to evaluate their reliability and validity. Results: Fifty patients completed the questionnaire. Reliability analysis results showed a pattern identification match rate of 86%, Cronbach's α coefficient of 0.834, and intraclass correlation coefficient of 0.907. The Mann - Whitney U test and logistic regression were implemented to check the relations between the survey questions and pattern identification results; the Pearson correlation, compared with other scales, showed a moderate score. Conclusion: We reorganized the standard tool for the pattern identification of GERD to be updated on current issues and so that it is easily used. The analysis results of the questionnaire showed that the reorganized standard tool had high reliability and moderate validity.

A Study on Verification of Back TranScription(BTS)-based Data Construction (Back TranScription(BTS)기반 데이터 구축 검증 연구)

  • Park, Chanjun;Seo, Jaehyung;Lee, Seolhwa;Moon, Hyeonseok;Eo, Sugyeong;Lim, Heuiseok
    • Journal of the Korea Convergence Society
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    • v.12 no.11
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    • pp.109-117
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    • 2021
  • Recently, the use of speech-based interfaces is increasing as a means for human-computer interaction (HCI). Accordingly, interest in post-processors for correcting errors in speech recognition results is also increasing. However, a lot of human-labor is required for data construction. in order to manufacture a sequence to sequence (S2S) based speech recognition post-processor. To this end, to alleviate the limitations of the existing construction methodology, a new data construction method called Back TranScription (BTS) was proposed. BTS refers to a technology that combines TTS and STT technology to create a pseudo parallel corpus. This methodology eliminates the role of a phonetic transcriptor and can automatically generate vast amounts of training data, saving the cost. This paper verified through experiments that data should be constructed in consideration of text style and domain rather than constructing data without any criteria by extending the existing BTS research.

Conservative Genes among 1,309 Species of Prokaryotes (원핵생물 1,309종의 보존적 유전자)

  • Lee, Dong-Geun
    • Journal of Life Science
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    • v.32 no.6
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    • pp.463-467
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    • 2022
  • As a result of applying the COG (Cluster of Orthologous Groups of Protein) algorithm to 1,309 species to confirm the conserved genes of prokaryotes, ribosomal protein S11 (COG0100) was identified. The numbers of conservative genes were 2, 5, 5, and 6 in 1,308, 1,307, 1,306, and 1,305 species, respectively. Twenty-nine genes were conserved in over 1,302 species, and they encoded 23 ribosomal proteins, 3 tRNA synthetases, 2 translation factors, and 1 RNA polymerase subunit. Most of them were related to protein production, suggesting the importance of protein expression in prokaryotes. The highest conservative COG was COG0048 (ribosomal protein S12) among the 29 COGs. The 29 conserved genes usually have one protein for each prokaryote. COG0090 (ribosomal protein L2) had not only the lowest conservation value but also the largest standard deviation of phylogenetic distance value. As COG0090 is not only a member of the ribosome, but also a regulator of replication and transcription, it could be inferred that prokaryotes have large variations in COG0090 to survive in various environments. This study could provide data necessary for basic science, tumor control, and development of antibacterial agents.

The Use of Information and Communication Technologies in Education of Students' Civic Responsibility

  • Sadovyi, Mykola;Terenko, Olena;Filimonova, Tetiana;Malanchuk, Serhii;Vovkochyn, Lyudmyla;Paslawska, Alla;Oros, Ildiko
    • International Journal of Computer Science & Network Security
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    • v.22 no.7
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    • pp.213-219
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    • 2022
  • Building Ukraine as an independent, sovereign state requires the education of a citizen-patriot, able to live and work in a democracy, ensure the unity of Ukraine, feel constant responsibility for themselves, their people, country, seek to make a real contribution to the reform process. Modern modernization of the education system requires the search for new information and communication technologies that can ensure the formation of a citizen with an active civic position, which involves not only students mastering the rights and responsibilities of citizens, convincing them of the feasibility of democratic transformation of society, patriotic qualities and feelings, but also the identification of motivated civic actions. The pandemic and hostilities have led to significant changes in the field of education around the world, they have caused educational problems in Ukraine. At the beginning of the quarantine in the spring of 2020, all educational institutions in the emergency mode switched to distance learning. Intensive use of information and communication technologies in the life of modern society has led to a rethinking of the content of education and training of future professionals: the main role is played not so much by the information itself as the ability to work with it, critically comprehend and produce new knowledge; the main thing is not the amount of information, but its quality; information is needed for further practical application and transformation into knowledge, and the ability to work with information becomes one of the important competencies of the modern specialist in the new transformation of society: from information to the knowledge society. In this context, one of the main forms of training is distance learning, which is able to respond to the challenges of society. The main methodological positions that are taken into account in the construction of the structure and dynamics of the formation of civic responsibility of the individual during the use of information and communication technologies are highlighted. The structure of civil responsibility as a holistic system of information and communication technologies is outlined, which includes three subsystems that characterize the natural, social and systemic qualities of citizenship, interconnected hierarchically and synergistically.The constituent elements of the structural part of the model of civic culture of the individual are analyzed.

A Study about Directing Aspects and Contemporary Assessments during the Period of Coterie System(1931.7.8.-1932.12) of Shingeuk Troupe 'Geukyesulyeonguhoe(1931.7.8.-1938.3)' - Focusing on the First Trial Performance (5Act) - (신극 단체 '극예술연구회(1931.7.8.-1938.3)'의 동인제 시기(1931.7.8-1932.12) 연출 양상과 평가들에 관한 논고 - 제1회 시연작 <검찰관>(5막)을 예로 하여 -)

  • Sung, Meung-Heyn
    • The Journal of the Korea Contents Association
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    • v.22 no.9
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    • pp.156-168
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    • 2022
  • This study was conducted to investigate the staging principle, the staging work and the trial performance of Shingeuk troupe Geukyesulyeonguhoe during the period of coterie system, focusing on Gogol work·Ham Daehoon translation·Hong Haeseong directing's (5Act). As a result, the first trial performance was based on a faithful full-scale description rather than an interpretive directing of play. It was a performance that focused on copying and implanting the external form of the performance stage of Shingeki troupe Tsukiji Little Theater. The general review of the time was summarized to the point that it was a relatively successful performance that exceeded expectations as a trial demonstration of amateur actors. However, in terms of the content of play and the form of performance, reservations and lack of contemporary(modern) interpretation caused the problem that the general audience was alienated. Therefore, it was difficult to achieve the effect of reflecting the reality of Chosun through , as Geukyesulyeonguhoe intended.

Calibration of Thermal Camera with Enhanced Image (개선된 화질의 영상을 이용한 열화상 카메라 캘리브레이션)

  • Kim, Ju O;Lee, Deokwoo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.4
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    • pp.621-628
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    • 2021
  • This paper proposes a method to calibrate a thermal camera with three different perspectives. In particular, the intrinsic parameters of the camera and re-projection errors were provided to quantify the accuracy of the calibration result. Three lenses of the camera capture the same image, but they are not overlapped, and the image resolution is worse than the one captured by the RGB camera. In computer vision, camera calibration is one of the most important and fundamental tasks to calculate the distance between camera (s) and a target object or the three-dimensional (3D) coordinates of a point in a 3D object. Once calibration is complete, the intrinsic and the extrinsic parameters of the camera(s) are provided. The intrinsic parameters are composed of the focal length, skewness factor, and principal points, and the extrinsic parameters are composed of the relative rotation and translation of the camera(s). This study estimated the intrinsic parameters of thermal cameras that have three lenses of different perspectives. In particular, image enhancement based on a deep learning algorithm was carried out to improve the quality of the calibration results. Experimental results are provided to substantiate the proposed method.

A Comparative Analysis of Economic Terms & Function Notations and Function Graphs in High School <Mathematics for Economics>, <Economics> Textbooks (고등학교 수학과 <경제 수학>, 사회과 <경제> 교과서에 나타난 경제 용어, 함수 기호 및 함수 그래프의 비교 분석)

  • Lee, Kyungwon;Kwon, Oh Nam
    • Communications of Mathematical Education
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    • v.36 no.4
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    • pp.559-587
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    • 2022
  • The purpose of this study is to derive implications for the development of the next curriculum and textbooks by comparing and analyzing the textbooks of the 2015 revised high school mathematics curriculum <Mathematics for Economics> and social studies curriculum <Economics>. In the <Mathematics for Economics> textbooks, economic terms and function notations should be introduced. Additionally, the use of graphs for economic-related functions is different from the use of graphs in mathematics in the <Mathematics for Economics> textbooks. For these reasons, the usage of economic terms, function notations, and function graphs covered in the <Mathematics for Economics> textbooks were compared and analyzed with the usage in the <Economics> textbooks. In the <Mathematics for Economics> textbooks, economic terms that are highly related to mathematics are defined and presented. Contrary to the conventions of mathematics and economics, the function notations in the <Mathematics for Economics> textbooks were used inconsistently because uppercase and lowercase letters were mixed in the function notations. Function graphs in the <Mathematics for Economics> textbooks had differences in the range of values represented by the variables regarding axes and scaling. The <Mathematics for Economics> textbooks did not provide a mathematical interpretation of the translation or slope. In the course of <Mathematics for Economics>, it is necessary to specify considerations for teaching and learning, and assessment in the curriculum to promote students' understanding of mathematics and economics. The descriptions in the curriculum document and textbooks of <Mathematics for Economics> should be supplemented to provide learning opportunities for mathematical interpretation of economics-related contents.

National Agenda Service Model Development Research of Policy Information Portal of National Sejong Library (국립세종도서관 정책정보포털 국정과제 서비스 모형개발 연구)

  • Younghee, Noh;Inho, Chang;Hyojung, Sim
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.33 no.4
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    • pp.73-92
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    • 2022
  • This study intends to design a model that can effectively service policy data necessary for the implementation of new national agenda in order to provide high-quality policy information services that go beyond those of the existing Policy Information Portal (POINT) of National Sejong Library. To this end, it was determined that providing an integrated search environment, in lieu of data search through individual access, was necessary. Subsequently, four possible models for a national agenda service model were presented. First, designing a computerized system for both interface and electronic information source aspects was proposed for the national agenda service system operation. Second, designing the Linked Open Data system and the time-series service system for national policy information, providing the translation service of overseas original data, and securing the researcher's desired data were presented for the national agenda service information source operation. Third, strengthening public relations for policy users, building and promoting the site brand, operating SNS channels, and reinforcing the activation of auxiliary materials and the accessibility of external services were proposed for public relations of national agenda service. Fourth, expanding the information network with Open API, cloud service, and overseas libraries was proposed for collaborating and cooperating with the agenda service.

Analysis of Problems in the Phase Diagram of the 2015 Revised Curriculum Chemistry II Textbook (2015 개정 교육과정 화학II 교과서의 상평형 그림에 대한 문제점 분석)

  • Youngha, Hwang;Seoung-Hey, Paik
    • Journal of the Korean Chemical Society
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    • v.67 no.1
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    • pp.54-63
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    • 2023
  • In this study, six types of 2015 revised curriculum ChemistryII textbooks were analyzed for conditions, definitions, whether or not critical points were displayed, and real-life examples of phase diagram. In this study, it was confirmed that the problems pointed out in several previous studies were not reflected in the 2015 revised curriculum ChemistryII textbook. The same as the situation defining the phase diagram, the translation of the phase diagram into a phase equilibrium diagram, the distinction between phase and state being unclear, the critical point not being shown in the phase diagram, real life examples are very limited what is being presented as is suggested as a problem. Therefore, it is necessary to reflect the results of various previous studies in the revised curriculum ChemistryII textbook that will be made in the future, specify the conditions under which the phase diagram is drawn, newly model the situation defining the phase diagram, and translate the phase diagram as a 'phase diagram'. It is necessary to use the term, clarify the distinction between phase and state, mark the critical point in the phase diagram, and develop various real-life examples.

Effect of serotonin on the cell viability of the bovine mammary alveolar cell-T (MAC-T) cell line

  • Xusheng, Dong;Chen, Liu;Jialin, Miao;Xueyan, Lin;Yun, Wang;Zhonghua, Wang;Qiuling, Hou
    • Journal of Animal Science and Technology
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    • v.64 no.5
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    • pp.922-936
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    • 2022
  • 5-Hydroxytryptamine (5-HT), a monoamine, as a local regulator in the mammary gland is a chemical signal produced by the mammary epithelium cell. In cows, studies have shown that 5-HT is associated with epithelial cell apoptosis during the degenerative phase of the mammary gland. However, studies in other tissues have shown that 5-HT can effectively promote cell viability. Whether 5-HT could have an effect on mammary cell viability in dairy cows is still unknown. The purpose of this study was to determine: (1) effect of 5-HT on the viability of bovine mammary epithelial cells and its related signaling pathways, (2) interaction between prolactin (PRL) and 5-HT on the cell viability. The bovine mammary alveolar cell-T (MAC-T) were cultured with different concentrations of 5-HT for 12, 24, 48 or 72 hours, and then were assayed using cell counting kit-8, polymerase chain reaction (PCR) and immunobloting. The results suggested that 20 μM 5-HT treatment for 12 or 24 h promote cell viability, which was mainly induced by the activation of 5-HT receptor (5-HTR) 1B and 4, because the increase caused by 5-HT vanished when 5-HTR 1B and 4 was blocked by SB224289 and SB204070. And protein expression of mammalian target of rapamycin (mTOR), eukaryotic translation elongation factor 2 (eEF2), janus kinase 2 (JAK2) and signal transducer and activator of transcription 5 (STAT5) were decreased after blocking 5-HT 1B and 4 receptors. When MAC-T cells were treated with 5-HT and PRL simultaneously for 24 h, both the cell viability and the level of mTOR protein were significantly higher than that cultured with 5-HT or PRL alone. In conclusion, our study suggested that 5-HT promotes the viability of MAC-T cells by 5-HTR 1B and/or 4. Furthermore, there is a reciprocal relationship between PRL and 5-HT.