• Title/Summary/Keyword: transit time

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Quantitative Evaluation of Dysphagia Using Scintigraphy (신티그라피를 이용한 연하곤란증의 정량적 평가)

  • Park, Seok-Gun;Hyun, Jung-Keun;Lee, Seong-Jae
    • The Korean Journal of Nuclear Medicine
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    • v.32 no.3
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    • pp.276-289
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    • 1998
  • Purpose: To evaluate dysphagia objectively and quantitatively, and to clarify the effect of neck position and viscosity changes in patients with aspiration and laryngeal penetration. Materials and Methods: We studied 35 patients with dysphagia and 21 normal controls using videofluoroscopy and scintigraphy. Videofluoroscopy was performed with barium with three different viscosity, and scintigraphy was done with water, yogurt, and steamed egg mixed with Tc-99m tin colloid. If aspiration was found during videofluoroscopic examination, patient's neck position was changed and study repeated. Videofluoroscopy was analyzed qualitatively. We calculated 7 quantitative parameters from scintigraphy. According to the videofluoroscopic findings, we divided patients into 3 subgroups; aspiration, laryngeal penetration, and no-aspiration group. Results: The result of videofluoroscopy revealed that the most common finding was the delay in triggering pharyngeal swallow. Pharyngeal transit time (PTT) and pharyngeal swallowing efficiency(PSE) in patients with aspiration were signifi-cantly different from other groups. After neck position change, aspiration could be reduced in all of 7 patients, and laryngeal penetration reduced by about 82%. PTT and PSE were also improved after position change. Aspiration and laryngeal penetration occurred more frequently in thin liquid swallowing than in thick liquid and solid swallowing. Conclusion: PTT and PSE were useful for the evaluation of dysphagia. Aspiration and laryngeal penetration could be reduced when appropriate position assumed. We could decrease the chance of aspiration by changing the patient diet consistency. Scintigraphy might be useful tool to quantitate and follow up these changes.

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Effects of Transient Treatment with Rotenone, a Mitochondrial Inhibitor, on Mouse Subventricular Zone Neural Stem Cells (미토콘드리아 저해제인 rotenone의 일시적 처리가 쥐의 뇌실 하 영역 신경 줄기 세포에 미치는 영향)

  • Park, Ki-Youb;Kim, Man Su
    • Journal of Life Science
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    • v.29 no.12
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    • pp.1329-1336
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    • 2019
  • Subventricular zone (SVZ) in the brain contains neural stem cells (NSCs) which self-renew and differentiate to neurons and glial cells during postnatal period and throughout adulthood. Since fate decision to either proliferation or differentiation has to respond to intracellular and extracellular conditions, many intrinsic and extrinsic factors are involved. Among them, mitochondria have been reported to participate in fate decision of NSCs. In our previous report, we showed that long-term treatment of a mitochondrial inhibitor rotenone greatly inhibited neurogenesis. In this study, we examined the effects of short-term treatment of rotenone on SVZ NSCs. We found that (1) even one-day treatment of rotenone significantly reduced neurogenesis and earlier time points seemed to be more sensitive to rotenone, (2) a number of Mash1+ transit amplifying cells was decreased by one-day treatment of rotenone, (3) short-term treatment of rotenone eliminated most of the differentiated Tuj1+ neurons and Olig2+ oligodendrocytes, while glial fibrillary acidic protein (GFAP)+ astrocytes were not affected, and (4) sulfiredoxin 1 (Srxn1) gene expression was increased after one-day treatment of rotenone, indicating activation of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway. All these results confirm that functional mitochondria are necessary during differentiation to neurons or oligodendrocytes as well as maintenance of neurons after differentiation. Also, these data suggest that temporary exposure to mitochondrial inhibitor such as rotenone might have long-term effects on neurogenic potential of NSCs.

Case Report on Dysphagia Related to The Wallenberg's Syndrome Improved by Acupuncture Therapy (침구치료를 통한 Wallenberg's syndrome 환자의 연하장애 치험례)

  • Yun Jone-Min;Park Sae-Wook;Lee Sun-Woo;Son Ji-Woo;Kim Yong-Jeong;Lee Seung-Eon;Cho Chang-Hyun;Cho Yoon-Soong;Lee In;Moon Byung-Soon;Lee Min-Goo
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.19 no.6
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    • pp.1701-1705
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    • 2005
  • Dysphagia is Swallowing disorder characterized by difficulty in oral preparation for the swallow or in moving material from the mouth to the stomach. Dysphagia is the one of the most symptom of CVA and predisposes to medical complications such as aspiration pneumonia in poststroke patients. This study was designed to report the clinical effects of acupuncture for dysphagia on a patient with Wallenberg's syndrome. 8 acupoint were used and videofluoroscopic evaluation were performed. According to the above evaluation, 'Oral transit time' decreased within 1.5 sec and 'Coating of pharyngeal wall after swallow' were disappeared. The above results suggest that acupuncture is beneficial for dysphagia.

A Study on the Satisfaction Differences in Dockless Bike in Suwon City (스테이션 없는 공유자전거 이용 만족도 차이 분석연구(수원시 사례를 중심으로))

  • Kim, Sukhee;Lee, Nam il
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.40 no.2
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    • pp.157-166
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    • 2020
  • The city of Suwon has introduced a dockless bike for the first time in Korea. In this study, a questionnaire was conducted for citizens to suggest improvement through satisfaction analysis. As a result of the survey, 88 % of respondents awarded the presence of a bike, and 90 % answered positively in terms of bike policy; whereas mature civic ethics showed an low satisfaction. For the purpose of usage, approximately 75 % of users mainly used for commuting, business, shopping, and the connection with mass transit. In the result of the primary means of a trip, a private car was most preferred before operation; However, it was found that mode transition has been actively carried out. This suggests significant implications for implementing sustainable urbanism. Meanwhile, The level of satisfaction significantly differed in the field of payment method, charge, usage guidance and publicity by an occupation and age groups commonly. Satisfaction in bike maintenance was statistically differed by an occupation. Satisfaction in Rental-return and registration procedures showed differences by an age groups. The results of this study will contribute to establishment related policies and to more activate dockless shared bike.

On the Development of Safety Requirements Based on Functional Analysis of LRT Stations in Concept Development Stage (경전철 역사 개념설계 단계에서 기능분석 결과를 활용한 안전요구사항의 생성방법에 관한 연구)

  • Kim, Joo-Uk;Jung, Ho-Jeon;Park, Kee-Jun;Kim, Joorak;Han, Seok Youn;Lee, Jae-Chon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.4
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    • pp.382-391
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    • 2016
  • For safety-critical systems including railways, there has been a growing need for effective and systematic safety management processes. The outcomes of efforts in this area are international safety standards, such as IEC 61508, 62278, and ISO 26262. One of the principal activities in the safety process is hazard analysis. For this reason, considerable efforts have been directed toward methods of hazard analysis. On the other hand, the hazard analysis methods reported thus far appear to be unclear in terms of their relationship with the system design process. In addition, in some cases, the methods appear to rely heavily on information regarding the hardware and software components, the number of which is increasing. These aspects can become troublesome when design changes are necessary. To improve the situation, in this paper, hazard analysis was carried out using the result of functional analysis early in the concept development stage for a safety-critical system design. Because hazard analysis is carried out at the system level and the result is then used to develop the safety requirements, improvements can be expected in terms of the development time and cost when design changes are required due to changes in the requirements. As a case study, the generation of safety requirements for the development of light rail transit stations is presented.

Effects of Resistant Starch on Gut Functions and Plasma Lipid Profiles in Rats Fed High Fat Diet (난소화성전분의 섭취가 고지방식이를 섭취한 흰쥐에서 장 기능과 혈액지방에 미치는 영향)

  • 정미경;김명환;강남이;김우경
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.31 no.2
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    • pp.271-276
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    • 2002
  • We have investigated the intestinal functions and hypolipidemic effects of resistant starch (RS) in rats. Experimental groups were CON (cooked starch 45% + RS 7%), RSIO (cooked starch 35% +RS 10%), RS20 (cooked starch 25%+RS20%), and RS30 (cooked starch 15%+RS 30%). The weight gains during experimental period were slightly decreased by intake of resistant starch and the weights of epididymal fat pad were lower in resistant starch intake groups than in CON, although the difference was not significant. In intestinal functions, water contents of fecal, transit time and colon cell proliferation were affected by resistant starch. Plasma total lipid and triglyceride concentrations were significantly decreased, dose-dependently, by resistant starch intake. Conclusively, it is important to intake resistant starch in order to decrease plasma lipids and to improve intestinal functions.

The Design of Feature Selection Classifier based on Physiological Signal for Emotion Detection (감성판별을 위한 생체신호기반 특징선택 분류기 설계)

  • Lee, JeeEun;Yoo, Sun K.
    • Journal of the Institute of Electronics and Information Engineers
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    • v.50 no.11
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    • pp.206-216
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    • 2013
  • The emotion plays a critical role in human's daily life including learning, action, decision and communication. In this paper, emotion discrimination classifier is designed to reduce system complexity through reduced selection of dominant features from biosignals. The photoplethysmography(PPG), skin temperature, skin conductance, fontal and parietal electroencephalography(EEG) signals were measured during 4 types of movie watching associated with the induction of neutral, sad, fear joy emotions. The genetic algorithm with support vector machine(SVM) based fitness function was designed to determine dominant features among 24 parameters extracted from measured biosignals. It shows maximum classification accuracy of 96.4%, which is 17% higher than that of SVM alone. The minimum error features selected are the mean and NN50 of heart rate variability from PPG signal, the mean of PPG induced pulse transit time, the mean of skin resistance, and ${\delta}$ and ${\beta}$ frequency band powers of parietal EEG. The combination of parietal EEG, PPG, and skin resistance is recommendable in high accuracy instrumentation, while the combinational use of PPG and skin conductance(79% accuracy) is affordable in simplified instrumentation.

Characterizing Par ticle Matter on the Main Section of the Seoul Subway Line-2 and Developing Fine Particle Pollution Map (서울시 지하철 2호선 본선구간의 입자상물질 농도 특성 및 미세분진의 오염지도 개발)

  • Lee, Eun-Sun;Park, Min-Bin;Lee, Tae-Jung;Kim, Shin-Do;Park, Duck-Shin;Kim, Dong-Sool
    • Journal of Korean Society for Atmospheric Environment
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    • v.32 no.2
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    • pp.216-232
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    • 2016
  • In present, the Seoul City is undergoing traffic congestion problems caused by rapid urbanization and population growth. Thus the City government has reorganized the mass transportation system since 2004 and the subway has become a very important means for public transit. Since the subway system is typically a closed environment, the indoor air quality issues have often raised by the public. Especially since a huge amount of PM (particulate matter) is emitted from ground tunnels passing through the subway train, it is now necessary to assess the characteristics and behaviors of fine PM inside the tunnel. In this study, the concentration patterns of $PM_1$, $PM_{2.5}$, and $PM_{10}$ in the Seoul subway line-2 were analyzed by real-time measurement during winter (Jan 13, 2015) and summer (Aug 7, 2015). The line-2 consisting of 51 stations is the most busy circular line in Seoul having the railway of 60.2 km length. The the one-day average $PM_{10}$ concentrations were $148{\mu}g/m^3$ in winter and $66.3{\mu}g/m^3$ in summer and $PM_{2.5}$ concentrations were $118{\mu}g/m^3$ and $58.5{\mu}g/m^3$, respectively. The $PM_{2.5}/PM_{10}$ ratio in the underground tunnel was lower than the outdoor ratio and also the ratio in summer is higher than in winter. Further the study examined structural types of underground subsections to explain the patterns of elevated PM concentrations in the line-2. The subsections showing high PM concentration have longer track, shorter curvature radius, and farther from the outdoor stations. We also estimated the outdoor PM concentrations near each station by a spatial statistical analysis using the $PM_{10}$ data obtained from the 40 Seoul Monitoring Sites, and further we calculated $PM_{2.5}/PM_{10}$ and $PM_1/PM_{10}$ mass ratios near the outdoor subway stations by using our observed outdoor $PM_1$, $PM_{2.5}$, and $PM_{10}$ data. Finally, we could develop pollution maps for outdoor $PM_1$ and $PM_{2.5}$ near the line-2 by using the kriging method in spatial analysis. This methodology may help to utilize existing $PM_{10}$ database when managing and control fine particle problems in Korea.

Real-time Reefer Container Control Device Using M2M Communication (M2M통신을 이용한 실시간 냉동컨테이너 제어 장비)

  • Moon, Young-Sik;Choi, Sung-Pill;Lee, Eun-Kyu;Kim, Tae-Hoon;Lee, Byung-Ha;Kim, Jae-Joong;Choi, Hyung-Rim
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.18 no.9
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    • pp.2216-2222
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    • 2014
  • A recent trend of increasing container traffic volume using reefer container demands continuous management of reefer container in transit. However, reefer containers can only be monitored at terminal or in ship during marine transportation instead of throughout entire section. In the case of inland transportation section using truck or train, monitoring is not possible currently. The reason is because the reefer container monitoring method using PCT recommended by IMO and conventional monitoring methods using TCP/IP, RFID communication require establishing additional communication infrastructure. This paper will propose a new reefer container control device that not only solves these problems and monitors during inland transportation section but also controls reefer container. Using data port attached to every reefer container, the proposed device collects the information of reefer container and using M2M communication technology, it transmits information to server without the need to establish additional communication infrastructure. In addition, it can control the operational status of reefer container upon receiving control information set in server such as temperature of reefer container.

Analytical Study on the Potential Risks from Right-Handled Vehicle Drivers (우측핸들차량 운전자의 잠재적 위험성 분석연구)

  • Park, Jun-Tae;Kim, Jeong-Hyun;Kang, Young-Kyun;Kim, Jang-Wook
    • Journal of Korean Society of Transportation
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    • v.30 no.2
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    • pp.67-78
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    • 2012
  • The current traffic regulations in Korea stipulate that traffic should keep to the right according to the Road Traffic Act; thus, customarily, the 'seat-on-the-left' system has been maintained. However, an increased number of 'seat-on-the-right' vehicles are being imported via a variety of routes from foreign countries, especially from Japan. According to the data from July 2004, 1,343 cargo vehicles and 593 passenger vehicles (for diplomats, etc.) were currently being driven on domestic road. As these 'seat-on-the-right' vehicles are not compatible with the domestic transportation system of driving on the right side of the road, there is a high risk of accidents. Experiments show that such system-driver mismatch causes longer operation time for directional signals, higher error frequency in yielding due to additional mental adjustments for 'seat-on-the-right' vehicle drivers. These are, therefore, influential factors which can lead to possible accidents. Furthermore, when the experiments test the visual range during overtaking maneuvers, the visual range of the drivers in the 'seat-on-the-left' vehicle was 2.95 meters as opposed to 1.7 meters for the drivers in the 'seat-on-the-right' vehicle. (In the experiment, the drivers were instructed to look at the paper cup 10 meters away from the back of drivers' seat.) The results demonstrate that it is necessary to have additional safety measures be implemented for the 'seat-on-the-right' vehicles.