• Korean Journal of Pharmacognosy
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• v.40 no.4
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• pp.388-393
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• 2009

Advanced glycation end products (AGEs) have been implicated in the development of diabetic complications. The AGEs inhibitors or cross-link breakers attenuate various functional and structural manifestations of diabetic complications. In this study, 64 herbal medicines from China and Vietnam have been investigated with an in vitro evaluation system using AGEs inhibitory activity. Of these, eight herbal medicines ($IC_{50}$<50 ${\mu}g$/ml) were found to have strong AGEs inhibitory activity compared with aminoguanidine (14 days, $IC_{50}$=75.98 ${\mu}g$/ml; 28 days, $IC_{50}$=88.27 ${\mu}g$/ml). Particularly, four herbal medicines, Buddleja officinalis (whole plant), Syzygium cuminii (leaf), Eugenia caryophyllate (seed), and Paeonia suffruticosa (root) showed more potent inhibitory activity (approximately 5-6 fold) than the positive control aminoguanidine.

• Korean Journal of Pharmacognosy
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• v.42 no.1
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• pp.46-53
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• 2011

Advanced glycation end products (AGEs) have been postulated to play a central role in the development of diabetic complications. A variety of different agents that inhibit AGEs have been under investigation. In this study, 66 herbal medicines from China have been investigated with an in vitro evaluation system using AGEs formation inhibitory activity. Of these, 31 herbal medicines ($IC_{50}$ < $50\;{\mu}g/ml$) were found to have significant AGEs formation inhibitory activity. Particularly, 5 herbal medicines, Camptotheca acuminata (branches and leaves), Quercus franchetii (branches), Camellia pitardii (leaves, branches, and fruits), Antidesma bunius (whole plants), and Loranthus parasiticus (whole plants) showed more potent inhibitory activity (approximately 6-20 fold) than the positive control aminoguanidine ($IC_{50}=52.96\;{\mu}g/ml$).

• Korean Journal of Pharmacognosy
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• v.42 no.2
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• pp.161-168
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• 2011

Advanced glycation end products (AGEs) has been shown to play an important role in the development of the diabetic complications. The AGEs inhibitors or cross-link breakers attenuate various functional and structural manifestations of diabetic complications. In this study, 69 China herbal medicines have been investigated with an in vitro evaluation system using AGEs inhibitory activity. Of these, 28 herbal medicines $IC_{50}$=<50 ${\mu}g/ml$) were found to have stronger AGEs inhibitory activity compared with aminoguanidine ($IC_{50}$=59.77 ${\mu}g/ml$). Particularly, 5 herbal medicines, Camptotheca acuminata (stem, leaf), Eurya groffii (stem, leaf), Cornus Capitata (leaf), Mucuna birdwoodiana (root), Nelumbo nucifera (fruit, seed) showed more potent inhibitory activity (approximately 6-27 fold) than the positive control aminoguanidine.

• Korean Journal of Pharmacognosy
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• v.37 no.1 s.144
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• pp.48-52
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• 2006

Advanced glycation end products (AGEs) are largely involved in the pathogenesis of diabetic complications. As part of our ongoing project directed toward the discovery of preventive and/or delay agents for diabetic complications from natural sources, 92 Korean traditional herbal medicines have been investigated with an in vitro evaluation system using AGEs inhibitory activity. Of these, 17 herbal medicines exhibited a significant inhibitory activity against AGEs formation. Particularly, 9 herbal medicines, i.e., Cinnamomi Cortex, Artemisiae Argyi Herba, Ammoni Tsao-ko Fructus, Menthae Herba, Amomi Semen, Polygoni Avicularis Herba, Lycopi Herba, Salviae Radix, and Nelumbinis Semen showed more potent inhibitory activity (2-4 fold) than the positive control aminoguanidine.

• Korean Journal of Pharmacognosy
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• v.40 no.4
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• pp.382-387
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• 2009

Enhanced formation and accumulation of advanced glycation end products (AGEs) have been implicated as a major pathogenesis process leading to diabetic complications, normal aging, atherosclerosis and Alzheimer's disease. In our ongoing project to discover novel treatments for diabetic complications from natural sources, we have investigated on the inhibitory activity of 67 ethanol extracts from 57 Korean herbal medicines against the formation of AGEs in vitro. Of these, 22 extracts were found to have a significant AGEs inhibitory activity ($IC_{50}$<50 ${\mu}g$/ml) compared with aminoguanidine ($IC_{50}$=75.98 ${\mu}g$/ml). Particularly, 6 extracts from 3 herbal medicines, Castanea crenata (flower, leaf, bark-twig), Acer tatarium subsp. ginnala (fruit) and Sapium japonicum (leaf, twig) showed (approximately 8-17 fold) stronger inhibitory activity than that of aminoguanidine.

• The International Journal of Costume Culture
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• v.4 no.1
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• pp.9-17
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• 2001

The purposes of the study are to find out the effect of clothing colors on perception of stimulus ages, occupations and images using stereotyping and color vision theories. The research method is a qualitative study and materials developed for the study are a set of stimuli and open-ended responses. The subjects were 1138 undergraduate students in Taejoen city, Chungbuk province. The data is analyze using content analysis, supplementary frequency and χ²analysis. The results are as follows : 1) The colors in Korean traditional costumes affected on the wearer's age perception : The red ensemble give the wearer the youngest look while the gray give the oldest look. 2) Mono-color ensemble wearers tend to give older look than bi-color ensemble wearers. 3) The chima colors and the jogori colors have similar impact on the wearer's age perception. 4) On image perception the jogori colors have more impact than the chima colors. 5) The colors in Korean traditional costumes are the clues to estimate the wearer's occupation.

• Korean Institute of Interior Design Journal
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• v.25 no.1
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• pp.56-64
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• 2016

Housing for the elderly should be planned on the base of elder's needs and preferences as well as their physical, emotional, and socio-psychological characteristics. This study examined the interior style of bedroom and living room the elderly preferred and these preferences are significantly different depending on their characteristics and cognitive ages, or not. This study was carried out by face to face interview with a questionnaire and 6 colored printed 3D images. The subjects were 202 old aged who lives in Busan. The interior style of bedroom and living room were classified into 3 styles; Korean traditional style, Western classical style, and modern style. The subjects made a choice their preferred interior style among three 3D images per each room and answered the reasons. Also, they answered their cognitive ages and general characteristics, and their preferences for the layout of living room-dining room-kitchen, use pattern, floor finishes, and furniture of bedroom and living room. The results were as follows; 1) The subjects preferred bed in bedroom and sofa in living room. Also, they wanted to finish the floor of bedroom and living room by using synthetic material, traditional floor paper, and wood. 2) The elderly preferred Western classical style of bedroom. The reasons were general mood such as warm, comfort, or bright, and the color. 3) These preferred styles were not any significant differences according to their characteristics and cognitive ages. 4) They preferred Korean traditional style, Western classical style, and modern style, in order. They preferred them for their general mood and window. 5) Their preferred styles were significantly different according to their housing types and cognitive ages.

• Journal of the Korean Society of Food Culture
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• v.7 no.2
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• pp.157-171
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• 1992

This study attempted to investigate the effect of housemaker's interest in dietary life on the knowledge of cooking principles and cooking methods, and on the daily meal management. Housemakers whose age ranged from 20 to 50 were surveyed in their residence. The results of this study were as follows. First, the level of interest in dietary life was positively related with ages, education and income levels. Moreover, housemaker who did not work or did not take care of relatives had higher level of interest in dietary life than those who did. Second, most housemakers bought foods and prepared a meal by themselves. The average time spent in preparing meals was 2 to 3 hours, and the number of side dishes cooked per day expect for the main dish was 5.46 percent of the total respondents ate out more than once a month for a 'family tie'. Third, there was no relation between the knowledge of cooking principle and the variables such as ages, education and income levels. Fourth, the level of the knowledge of cooking method about Korean traditional dishes was positively related with ages, education and income levels. In addition, housemakers who did not work or did not take care of relatives had less knowledge of Korean traditional dishes than those who did. Finally, the interest in dietary life was significantly correlated with the knowledge of cooking principle and cooking method of Korean traditional dishes.

• Korean Institute of Interior Design Journal
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• v.24 no.3
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• pp.95-103
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• 2015

Many housing alternatives and design guidelines for the elderly have been suggested along with the rapid increase of old persons. However, most of them focused on the spatial composition and fixtures. They do not address on interior style which affects on interior mood. The interior style is especially important to the elderly who spend most of their time in indoor space, such as housing unit or nursing home. On the base of these backgrounds, the purpose of this study is to examine what interior style of bedroom and living room where the elderly lives are and whether they are significantly different depending on their cognitive ages, or not. The subject were 202 old persons who lived in Busan. Their ages were more than 65 years. They were interviewed by using 3D images of bedroom and living room. Each one consisted of three interior styles; Korean traditional style, Western classical style, and modern style. The results were as followings; The interior style of bedroom and living room which the old persons lived were different depending on the elderly's cognitive ages. The younger the old persons' cognitive ages were, they lived in bedroom or living room of modern style. Also, the older their cognitive ages were, they lived in bedroom or living room of Korean traditional style. These results show that the cognitive age of the old persons affect the characteristics of interior design which they live. Also, it implies that the elderly are not one homogeneous group, but a heterogeneous one.

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.383.2-383.2
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• 2002

Diabetic nephropathy is major chronic complication of diabetes mellitus. Advanced glycation endproducts(AGEs) are largely involved in the pathogenesis of diabetic nephropathy. The irreversibly formed AGEs do not return to normal even if hyperglycemia is corrected and continue to accumulate over the lifetime of protein. The AGEs inhibitor. aminoguanidine(AG), is the only protein glycation inhibitor currently under development. its safety however is desirable. To find possible AGEs inhibitor in herbal medicines, bovine serum albumin was added to a mixture of sugars and some of processed. unprocessed herbal medicines or AG. Cyperi rhizoma was processed in four different methods according to chinese pharmacopoeia and traditional literatures. In comparision to the negative control with no inhibitor and positive control with AG. alcoholic extracts of these processed cyperi rhizoma proved to have more potent inhibitory activities than that of unprocessed cyperi rhizoma. These results revealed that some processed herbal medicines have a more potent in vitro inhibitory action on AGEs formation than AG. suggesting the possible candidate for diabetic nephropathy from the processed herbal medicines.