• Bulletin of the Korean Chemical Society
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• v.11 no.2
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• pp.131-134
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• 1990

Cytochrome c induces fusion of phosphatidylserine /phosphatidylethanolamine vesicles while apocytochrome c does not have a fusogenic capability despite the fact that the apoprotein binds to the vesicles more extensively. In order to see whether the difference in the fusogenic behavior comes from the topological variation in membrane bound proteins, the holoprotein and apoprotein were labeled with phenylisothiocyanate, a hydrophobic label, in the presence of its hydrophilic analogue p-sulfophenylisothiocyanate. Apocytochrome c was labeled with the hydrophobic probe more extensively than the cytochrome c, indicating that the apoprotein penetrates deeper into the bilayer than cytochrome c does. The translocation experiments of these proteins by trypsin entrapped vesicles further supported this conclusion.

• Korean Institute of Interior Design Journal
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• v.21 no.4
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• pp.40-47
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• 2012

Courtyard is evolving from the conventional one element of a building far beyond into independent peremeter of urban architecture, of which function has been darmatically upgraded from embedded traditional air fluiding, nutural lighting system into where full fledged function can be experienced so much as your imagimation reaches taking major social responsibility such as intact offline social networking which links people from neighbors, inter / extra buiding openness which allow people can communicate among othewise between themselves and artificial natural environmental emelents supplier where people resort to relaxation and natural healing. Roles of courtyard has been by far streatched out into nearby natural healing space where people can shake off their unavoidable stresses from the modern life relaxing themselves looking at the sky otherwise observe natural surroundigns such as plants, flowers and waters. Thanks to hereonto mentioned its merits, Courtyard building is widely used and seen as a center of modern urban design in residence, public bilding and urban planned buildings. Courtyard biulding is nowadays boasting their morphological diversity brought out from lots of topological variation, type variants, cross section and inter relationship with the other neighboring spaces. Hence, hereby I have been studied how above mentioned three major peremeters of courtyard has been upgraded in modern architecture comparing the period from 1960 to 1990 and the period starting from 1991.

• Journal of the Korean Institute of Intelligent Systems
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• v.13 no.4
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• pp.461-468
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• 2003

In a sequence of images obtained by surveillance cameras, facial regions appear very small and their colors change abruptly by lighting condition. This paper proposes a new face detection scheme, robust on complex background, small size, and lighting conditions. The proposed method is consisted of three processes. In the first step, the candidates for the face regions are selected using face color distribution and motion information. In the second stage, the non-face regions are removed using face color ratio, boundary ratio, and average of column-wise intensity variation in the candidates. The face regions containing eyes and mouth are segmented and classified, and then they are scored using their topological relations in the last step. To speed up and improve a performance the above process, a block based image segmentation technique is used. The experiments have shown that the proposed algorithm detects faced regions with more than 91% of accuracy and less than 4.3% of false alarm rate.

• Progress in Superconductivity
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• v.6 no.1
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• pp.13-18
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• 2004

High-.ate in-situ$ YBa_2$Cu$Cu_3$$O_{7-x}$ (YBCO) film growth was demonstrated by means of the electron beam co-evaporation. Even though our oxygen pressure is low, ∼$5 ${\times}$10^{-5}$ Torr, we can synthesize as-grown superconducting YBCO films at a deposition rate of around 10 nm/s. Relatively high temperatures of around 90$0^{\circ}C$ was necessary in this process so far, and it suggests that this temperature at a given oxygen activity allows a Ba-Cu-O liquid formation along with an YBCO epitaxy. Local critical current density shows a clear correlation with local resistivity. Homogeneous transport properties with a large critical current density ($4 ∼ 5 MA/\textrm{cm}^2$ at 77K, 0T) are observed in top faulted region while it is found that the bottom part carries little supercurrent with a large local resistivity. Therefore, it is possible that thickness dependence of critical current density is closely related with a topological variation of good superconducting paths and/or grains in the film bodies. The information derived from it may be useful in the characterization and optimization of superconducting films for electrical power and other applications.

• Proceedings of the Korean Institute of Surface Engineering Conference
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• 2017.05a
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• pp.3-23
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• 2017

The achievement of tissue engineering can be highly depending on the capability to generate complicated, cell seeded three dimensional (3D) micro/nano-structures. So, various fabrication techniques that can be used to precisely design the architecture and topography of scaffolding materials will signify a key aspect of multi-functional tissue engineering. Previous methods for obtaining scaffolds based on top-down are often not satisfactory to produce complex micro/nano-structures due to the lack of control on scaffold architecture, porosity, and cellular interactions. However, a bioprinting method can be used to design sophisticated 3D tissue scaffolds that can be engineered to mimic the tissue architecture using computer aided approach. Also, in recent, the method has been modified and optimized to fabricate scaffolds using various natural biopolymers (collagen, alginate, and chitosan etc.). Variation of the topological structure and polymer concentration allowed tailoring the physical and biological properties of the scaffolds. In this presentation, the 3D bioprinting supplemented with a newly designed plasma treatment for attaining highly bioactive and functional scaffolds for tissue engineering applications will be introduced. Moreover, various in vivo and in vitro results will show that the fabricated scaffolds can carry out their structural and biological functionality.

• Journal of Microbiology and Biotechnology
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• v.25 no.10
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• pp.1670-1679
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• 2015

Two hollow fiber membrane biofilm reactors (HF-MBfRs) were operated for autotrophic nitrification and hydrogenotrophic denitrification for over 300 days. Oxygen and hydrogen were supplied through the hollow fiber membrane for nitrification and denitrification, respectively. During the period, the nitrogen was removed with the efficiency of 82-97% for ammonium and 87-97% for nitrate and with the nitrogen removal load of 0.09-0.26 kg NH₄⁺-N/m³/d and 0.10-0.21 kg NO₃^--N/m³/d, depending on hydraulic retention time variation by the two HF-MBfRs for autotrophic nitrification and hydrogenotrophic denitrification, respectively. Biofilms were collected from diverse topological positions in the reactors, each at different nitrogen loading rates, and the microbial communities were analyzed with partial 16S rRNA gene sequences in denaturing gradient gel electrophoresis (DGGE). Detected DGGE band sequences in the reactors were correlated with nitrification or denitrification. The profile of the DGGE bands depended on the NH₄⁺ or NO₃^- loading rate, but it was hard to find a major strain affecting the nitrogen removal efficiency. Nitrospira-related phylum was detected in all biofilm samples from the nitrification reactors. Paracoccus sp. and Aquaspirillum sp., which are an autohydrogenotrophic bacterium and an oligotrophic denitrifier, respectively, were observed in the denitrification reactors. The distribution of microbial communities was relatively stable at different nitrogen loading rates, and DGGE analysis based on 16S rRNA (341f /534r) could successfully detect nitrate-oxidizing and hydrogen-oxidizing bacteria but not ammonium-oxidizing bacteria in the HF-MBfRs.

• Journal of KIISE:Computer Systems and Theory
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• v.36 no.3
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• pp.149-157
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• 2009

The crossed cube, a variation of the hypercube, possesses a better topological property than the hypercube in its diameter that is about half of that of the hypercube. It has been known that an N-node complete binary tree is a subgraph of an (N+1)-node crossed cube [P. Kulasinghe and S. Bettayeb, 1995]. However, efficient embedding methods have not been known for the case that the number of nodes of the complete binary tree is greater than that of the crossed cube. In this paper, we show that an N-node complete binary tree can be embedded into an M-node crossed cube with dilation 1 and load factor [N/M], N>M$\geq$2. The dilation and load factor is optimal. Our embedding has a property that the tree nodes on the same level are evenly distributed over the crossed cube nodes. The property is especially useful when tree-structured algorithms are processed on a crossed cube in a level-by-level way.

• Computational Structural Engineering
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• v.9 no.3
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• pp.169-177
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• 1996

The focus of this study is on the problem of the design of structure of undetermined topology. This problem has been regarded as being the most challenging of structural optimization problems, because of the difficulty of allowing topology to change. Conventional approaches break down when element sizes approach to zero, due to stiffness matrix singularity. In this study, a novel nonlinear programming formulation of the topology problem is presented. Its main feature is the ability to account for topology variation through zero element sizes. Stiffness matrix singularity is avoided by embedding the equilibrium equations as equality constraints in the optimization problem. Although the formulation is general, two dimensional plane elasticity examples are presented. The design problem is to find minimum weight of a plane structure of fixed geometry but variable topology, subject to constraints on stress and displacement. Variables are thicknesses of finite elements, and are permitted to assume zero sizes. The examples demonstrate that the formulation is effective for finding at least a locally minimal weight.

• Journal of the Korean Institute of Intelligent Systems
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• v.11 no.3
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• pp.223-230
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• 2001

Since self-organizing map (SOM) preserves the topology of ordering in input spaces and trains itself by unsupervised algorithm, it is Llsed in many areas. However, SOM has a shortcoming: structure cannot be easily detcrmined without many trials-and-errors. Structure-adaptive self-orgnizing map (SASOM) which can adapt its structure as well as its weights overcome the shortcoming of self-organizing map: SASOM makes use of structure adaptation capability to place the nodes of prototype vectors into the pattern space accurately so as to make the decision boundmies as close to the class boundaries as possible. In this scheme, the initialization of weights of newly adapted nodes is important. This paper proposes a method which optimizes SASOM with genetic algorithm (GA) to determines the weight vector of newly split node. The leanling algorithm is a hybrid of unsupervised learning method and supervised learning method using LVQ algorithm. This proposed method not only shows higher performance than SASOM in terms of recognition rate and variation, but also preserves the topological order of input patterns well. Experiments with 2D pattern space data and handwritten digit database show that the proposed method is promising.

• Journal of the Architectural Institute of Korea Planning & Design
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• v.35 no.12
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• pp.83-92
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• 2019

The purpose of this study is to analyze the continuous forms of time and space that work as architectural design principles of the Memorial to the Murdered Jews of Europe (Jewish Memorial). Continuity is divided into two, physical and non-physical attributes. The former extends from small installations to furnitures, finishes, spatial composition, and even spatial networks that complete architecture, and the latter is tied to time, from traditional to historical, developmental, commemorative or memorial elements. They are inherent in architecture as continuous forms. The Jewish Memorial is analyzed by the analysing framework of these two items. The analysis of the two layers can be summarized as follows; physical continuity is found in the space networks of the Memorial's inside and outside, the undulating spaces, the finishes, the small furnitures and installations, the entrances of staircases, the expanded underground of the ground order, and non-physical continuity manifests in the topological variation of spatiality, the morphological development of memorial architecture, the connection of semantic sense of space, and the superposition of historicity and modernity. These forms of continuity do not aestheticize the German enormity history, but make the meaning of the Memorial into non-superficial, in-depth architecture as a monument. Thus, the results of this study show that physical and non-physical continuity should be considered as the important design principles of architecture that makes the Memorial architecture possible.