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Pilot Study of Measuring Daily Quality of Life in Breast Cancer Patients Through Mobile Application (모바일 응용프로그램을 이용한 유방암 환자의 삶의 질 측정 초기연구)

  • Youn, So Young;Lee, Jong Won;Jung, Kyung Hae;Kim, Jeong Eun;Lee, Jae-Ho;Lee, Guna;Ahn, Sei Hyun;Shin, Yong-Wook
    • Anxiety and mood
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    • v.9 no.2
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    • pp.128-134
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    • 2013
  • Objective : As treatments for breast cancer require long period of time, the patients need continuous monitoring and management of their health related quality of life. The purpose of this preliminary study is to explore the utility of monitoring quality of life using a mobile phone based application, which was developed to enable the patients to report daily quality of life more efficiently. Methods : Department of psychiatry, breast cancer center and U-health team of Asan Medical Center collaborated in developing a mobile application titled 'DugunDugun'. Through the application, patients with breast cancer receiving neo-adjuvant chemotherapy could report on various questions about their daily quality of life. We extracted and explored the daily basis of the data of sleep duration, number of awake, sleep satisfaction, mood and anxiety from nine patients who reported on the questionnaire for more than a month. Results : The longitudinal data collected using our mobile application well represented the characteristics of individual sleep patterns and daily emotional changes. Most of the patients showed high daily variations in the scores of their quality of life while their averaged scores were similar among patients. The patient with highest daily variations in the subjective sleep quality and daily emotional change had highest score corresponding to moderate depression in Beck Depression Inventory (BDI). Conclusion : The results suggest that mobile application could be a useful tool for monitoring and collecting the daily quality of life in the patients with breast cancer. We expect that mobile application could facilitate early detection and proper intervention for the cancer patients at psychological crisis.

Analysis of Slope Fracturing using a Terrestrial LiDAR (지상라이다를 이용한 사면파괴 거동분석)

  • Yoo, Chang-Ho;Choi, Yun-Soo;Kim, Jae-Myeong
    • Spatial Information Research
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    • v.16 no.3
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    • pp.279-290
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    • 2008
  • Landslide, one of the serious natural disasters, has Incurred a large loss of human and material resources. Recently, many forecasting or alarm systems based on various kinds of measuring equipment have been developed to reduce the damage of landslide. However, only a few of these equipments are guaranteed to evaluate the safety of whole side of land slope with their accessibility to the slope. In this study, we performed some experiments to evaluate the applicability of a terrestrial LiDAR as a surveying tool to measure the displacement of a land slope surface far a slope collapsing protection system. In the experiments, we had applied a slope stability method to a land slope and then forced to this slope with a load increasing step by step. In each step, we measured the slope surface with both a total station and a terrestrial LiDAR simultaneously. As the result of Slope Fracturing analysis using all targets, the LiDAR system showed that three was 1cm RMSE on X-axis, irregularity errors on Y-axis and few errors on Z-axis compare with Total Station. As the result of Slope Fracturing analysis using continuous targets, the pattern of Slope Fracturing was different according to the location of continuous targets and we could detect a continuous change which couldn't be found using Total station. The accuracy of the LiDAR data was evaluated to be comparable to that of the total station data. We found that a LiDAR system was appropriate to measuring the behaviour of land slope. The LiDAR data can cover the whole surface of the land slope, whereas the total station data are available on a small number of targets. Moreover, we extracted more detail information about the behavior of land slope such as the volume and profile changes using the LiDAR data.

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Study on the procedure to obtain an attainable speed in pack ice

  • Kim, Hyun Soo;Jeong, Seong-Yeob;Woo, Sun-Hong;Han, Donghwa
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.10 no.4
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    • pp.491-498
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    • 2018
  • The cost evaluation for voyage route planning in an ice-covered sea is one of the major topics among ship owners. Information of the ice properties, such as ice type, concentration of ice, ice thickness, strength of ice, and speed-power relation under ice conditions are important for determining the optimal route in ice and low operational cost perspective. To determine achievable speed at any designated pack ice condition, a model test of resistance, self-propulsion, and overload test in ice and ice-free water were carried out in a KRISO ice tank and towing tank. The available net thrust for ice and an estimation of the ice resistance under any pack ice condition were also performed by I-RES. The in-house code called 'I-RES', which is an ice resistance estimation tool that applies an empirical formula, was modified for the pack ice module in this study. Careful observations of underwater videos of the ice model test made it possible to understand the physical phenomena of underneath of the hull bottom surface and determine the coverage of buoyancy. The clearing resistance of ice can be calculated by subtracting the buoyance and open water resistance form the pre-sawn ice resistance. The model test results in pack ice were compared with the calculation results to obtain a correlation factor among the pack ice resistance, ice concentration, and ship speed. The resulting correlation factors were applied to the calculation results to determine the pack ice resistance under any pack ice condition. The pack ice resistance under the arbitrary pack ice condition could be estimated because software I-RES could control all the ice properties. The available net thrust in ice, which is the over thrust that overcomes the pack ice resistance, will change the speed of a ship according to the bollard pull test results and thruster characteristics (engine & propulsion combination). The attainable speed at a certain ice concentration of pack ice was determined using the interpolation method. This paper reports a procedure to determine the attainable speed in pack ice and the sample calculation using the Araon vessel was performed to confirm the entire process. A more detailed description of the determination of the attainable speed is described. The attainable speed in 1.0 m, 90% pack ice and 540 kPa strength was 13.3 knots.

Geochemical Application for Clarifying the Source Material of the Earthenware: A Preliminary Study for Archaeological Application of Geochemical Tool (도토기의 태토(기원물질)산지를 추적하기 위한 지구화학적 응용연구: 지구화학연구기법의 고고학적 응용을 위한 기초연구)

  • Lee, Seung-Gu;Lee, Kil-Yong;Yoon, Yoon-Yeol;Yang, Myeong-Kwon;Kim, Kyu-Ho;Lee, Sung-Joo;Ahn, Sang-Doo
    • The Journal of the Petrological Society of Korea
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    • v.19 no.3
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    • pp.181-197
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    • 2010
  • This study is for finding a geoscientific factor for clarifying the source soil of the ancient earthenware finding. The used samples were the earthenware, soil and rocks, which were collected at the Gyeongju, Gyeongsan and Haman area. The chemical and mineralogical study for the samples were carried out for understanding the change of mineralogical and chemical composition among them. The mineralogical compositions of the earthenware are different from those of the soils from the surrounding area, which suggests that the mineralogical approach for clarifying the source soil of the earthenware should be difficult. Major element compositions of the earthenware also are different from those of the surrounding soils, which suggests that the comparison of the chemical composition using the major elements might be difficult for deducing the source soil of the earthenware. However, PAAS-normalized rare earth element (REE) patterns and Nd model ages among the rock, soils and earthenware from the same sampling sites show similar characteristics one another compared to those of the major element compositions. Nd-Sr isotopic systematics among the earthenware, soils and rocks also show a close relationship. Our results suggest that REE and Nd-Sr isotope geochemistry might be more useful than the other geochemical technique in clarifying the source soils of the ancient earthenware.

Effect of Repetitive Magnetic Stimulation on Proliferation and Viability of Adipose Tissue-Derived Stromal Cells (반복자기자극이 지방유래 중간엽 줄기세포 증식과 활성에 미치는 영향)

  • Kim, Su-Jeong;Park, Hea-Woon;Cho, Yun-Woo;Lee, Joon-Ha;Seo, Jeong-Min;Shin, Hyoun-Jin;Kang, Jae-Hoon;Ahn, Sang-Ho
    • The Journal of Korean Physical Therapy
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    • v.21 no.3
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    • pp.87-93
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    • 2009
  • Purpose: TThis study examined the effect of repetitive magnetic stimulation (RMS) on the viability and proliferative response of human adipose tissue-derived stromal cells (hATSCs) in vitro. Methods: The hATSCs were cultured primarily from human adipose tissue harvested by liposuction and incubated in a $37^{\circ}C$ plastic chamber. The cells were exposed to a repetitive magnetic field using a customized magnetic stimulator (Biocon-5000, Mcube Technology). The RMS parameters were set as follows: repetition rate=10Hz, 25Hz (stimulus intensity 100%= 0.1 Tesla, at 4cm from the coil), stimulated time= 1, 5, and 20 minutes. Twenty four hours after one application of RMS, the hATSCs were compared with the sham stimulation, which were kept under the same conditions without the application of RMS. The cells were observed by optical microscopy to determine the morphology and assessed by trypan blue staining for cell proliferation. The apoptosis and viability of the hATSCs were also analyzed by fluorescence-activated cell sorting (FACS) analysis of Annexin V and MTT assay. Results: After RMS, the morphology of the hATSCs was not changed and the apoptosis of hATSCs were not increased compared to the sham stimulation. The viability of the cells was similar to the cells given the sham stimulation. Interestingly, the level of hATSC proliferation was significantly higher in all RMS groups. Conclusion: The application of RMS may not cause a change in morphology and viability of hATSCs but can increase the level of cell proliferation in vitro. RMS might be useful as an adjuvant tool in combination with stem cell therapy without adverse effects.

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Toxicity and Behavioral Changes of Medaka (Oryzias latipes) by Brine Exposure (송사리(Oryzias latipes)를 이용한 고염해수의 생태독성 및 단기적 행동변화에 관한 연구)

  • Yoon, Sung-Jin;Park, Gyung-Soo
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.16 no.1
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    • pp.39-51
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    • 2011
  • Acute toxicity test and behavioral change analysis of seawater acclimated Japanese medaka were conducted to identify the brine effects on fish by seawater desalination. 7 day acute toxicity test of brine revealed linear concentration-response relationship from 40.0~80.0 psu treatment groups. There was no significant brine effect for 30-40 psu groups and mass mortality was observed from >50 psu exposure (7-day $LC_{50}$=51.4 psu). Images from the real time camera system were analyzed to observe the changes in behavioral patterns of medaka exposed to various salinity. 40.0 and 50.0 psu exposed groups were stabilized in behavioral patterns after 3.1 and 4.6 hours, respectively and 60.0 psu group showed sharp increase in activity during first 12 hours and 50% mortality thereafter. Similar patterns were observed to 70 and 80 psu groups and both experimental groups showed 100% mortality within 12 hours. Acute toxicity test and behavioral patterns showed very similar toxicity results which revealed the increases in mortality and behavioral activities from 50.0 psu. This critical salinity for fish impacts must be implemented to brine discharge strategy by seawater desalination into the coastal area. Also, we recommend that real time camera monitoring system must be a useful tool for early warning of fish toxicity for other applications. This research was funded by Ministry of Land, Transport and Maritime Affairs, Korea.

Direct Determination of Soil Nitrate Using Diffuse Reflectance Fourier Transform Spectroscopy (DRIFTS) (중적외선 분광학을 이용한 토양 내의 질산태 질소 정량분석)

  • Choe, Eunyoung;Kim, Kyoung-Woong;Hong, Suk Young;Kim, Ju-Yong
    • Korean Journal of Soil Science and Fertilizer
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    • v.41 no.4
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    • pp.267-272
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    • 2008
  • Mid-infrared (MIR) spectroscopy, particularly Fourier transform infrared spectroscopy (FTIR), has emerged as an important analytical tool in quantification as well as identification of multi-atomic inorganic ions such as nitrate. In the present study, the possibility of quantifying soil nitrate via diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) without change of a sample phase or with least treated samples was examined. Four types of soils were spectrally characterized in terms of unique bands of soil contents and interferences with nitrate bands in the range of $2000-1000cm^{-1}$. In order to reduce the effects of soil composition on calibration model for nitrate, spectra transformed to the 1st order derivatives were used in the partial least squared regression (PLSR) model and the classification procedure associated with input soil types was involved in calibration system. PLSR calibration models for each soil type provided better performance results ($R^2$>0.95, RPD>6.0) than the model considering just one type of soil as a standard.

The Development of HACCP-Based Standardized Recipe and the Quality Assessment of Cook/Chilled Soy Sauce Glazed Mackerel (쿡췰(Cook/Chill)시스템을 이용한 고등어조림의 HACCP 레시피 개발 및 생산과정의 품질평가)

  • Kwak, Tong-Kyung;Lee, Kyung-Eun;Park, Hye-Won;Ryu, Kyung;Hong, Wan-Soo;Choi, Eun-Jung;Jang, Hye-Ja;Kim, Sung-Hee
    • Korean journal of food and cookery science
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    • v.13 no.5
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    • pp.592-601
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    • 1997
  • The purposes of this study were to develop Hazard Analysis Critical Control Point-based standardized recipe applicable to cook/chilled soy sauceglazed mackerel and to evaluate the qualities related to the product flow of this item. After conducting experimental cooking, preliminary test, and analysis of recipes, critical control points were identified, control methods were determined, and HACCP-based recipe was standardized. At each critical control point, time-temperature profile was recorded and microbiological analysis (total aerobic plate counts, psychrotrophic plate count, coliform, and fecal coliform count), chemical analysis (pH, acid value and volatile based nitrogen (VBN)) and sensory evaluation of the item were done. Time-temperature data showed that the time the menu item had passed through temperature danger zone (5∼60$^{\circ}C$) during all phases was 60 min. At rapid cooling, but after cooling at room temperature, the temperature of this menu item did not drop below the ambient temperature. The results of microbiological test were negative throughout all phases following cooking and the results of chemical analysis did not change significantly in terms of storage periods except for VBN which increased on 7th day significantly(p<0.05). After steam/convection oven reheating and microwave oven reheating, the sensory score of the only appearance decreased significantly related to the storage time of overall quality profiles. But significant differences were not detected according to two reheating methods. In conclusion, this HACCP-based recipe was considered as an effective tool for assuring microbial as well as sensory quality of this cook/chilled item.

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High School Students' Knowledge and Attitude about Smoking according to Their Smoking Status (일 지역 고등학생의 흡연상태에 따른 흡연지식과 흡연태도)

  • Choi, Yeon-Hee;Paek, Kyung-Shin
    • Research in Community and Public Health Nursing
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    • v.15 no.2
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    • pp.277-288
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    • 2004
  • Purpose: This study was to provide basic information for preventing high school students from smoking by examining their actual smoking condition and their knowledge and attitude about smoking. Method: The subjects were 515 students selected from six(6), high schools in Jecheon. Data were collected using a questionnaire from the 1st to the 17th of December 2002. The author prepared the tool by modifying the scale of knowledge and attitude about smoking developed by Moon(2001). Data were analyzed with SPSS/WIN program using frequencies, percentages, $x^2$-test, t-test, ANOVA. Duncan test and Pearson's correlation coefficient. Result: 1. The percentage of ex-smoking students was 29.9% of male students and 18.6% of female ones. The percentage of currently smoking students was 23.9% of male students and 3.0% of female ones. The percentage of non-smoking students was 46.2% of male students and 78.4% of female ones, 2. There were not significant differences in smoking knowledge according to smoking status in male and female students. 3. There were significant differences in smoking attitude according to smoking status in male(F=32.70, p=.000) and female(F=11.15, p=.000) students. 4. In smoking status according to general characteristics, there were significant differences according to the type of school($x^2$=32.93, p=.000), grade($x^2$=11.91, p=.018), educational level of the father($x^2$=30.52, p=.000) and the mother($x^2$=14.23, p=.027), monthly allowance($x^2$=17.19, p=.028), harmony of family members($x^2$=15.23, p=.019), school life($x^2$=26.96, p=.00l) and school record($x^2$=30.24, p=.000). 5. In smoking status according to smoking-related characteristics, there were significant differences according to experience in cigarette purchase($x^2$=150.04. p=.000), experience in errands for cigarette($x^2$=20.00, p=.000), knowledge of cigarette price($x^2$=72.52, p=.000), close friends' smoking($x^2$=107.41. p=.000) and smoking of brothers and sisters($x^2$=16.97, p=.002). 6. There were significant correlation between knowledge and attitude about smoking in the whole students(r=.337. p=.000), ex-smokers(r=.324. p=.000), non-smokers(r=.369. p=.000) but there was not a significant correlation between knowledge and attitude about smoking in current smokers(r=.128. p=.30l). Conclusion: Smoking prevention education should considered students' smoking status. Current smokers need smoking prevention education aiming to change their attitude toward smoking in order for them to reduce smoking and to practice smoking cessation.

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The Effectiveness of Cardiopulmonary Resuscitation Training Targeted for Nursing Students (간호학생에게 실시한 심폐소생술 교육의 효과)

  • Han Jung-Suk;Ko Il-Sun;Kang Kyu-Sook;Song In-Ja;Moon Seong-Mi;Kim Sun-Hee
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.6 no.3
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    • pp.493-506
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    • 1999
  • The purpose of the study is to evaluate the effectiveness and competence level of trainees of Cardiopulmonary resuscitation training targeted for nursing students. 70 nursing students of Y nursing college are recruited as subjects from Dec. 1st, 1998 through Dec. 8th. 1998. For the pre-test. demographic data related to CPR and knowledge of CPR were evaluated. For the post-test, the next week of pre-test, three difference groups of subjects were tested their knowledge of CPR. CPR training was designed by two components which were 90 mins lecture and demonstration by one professor and individual practice using two educational models with two professors. As the tool of measurement estimating pre or post knowledge of CPR. questionnaires were developed based on self-diagnosis questionnaires of American Heart Association(AHA). The questionnaires were multiple choices (50 questions) and open end questions regarding CPR process. Each multiple choices questions valued 2 points (Score varied min. 0 point to max 100 points.). Collected data were computerized and analyzed by SPSS-WIN. Frequency and percentage of each questions analyzed. The differences of the knowledge and competency level of subjects between pre and post test was analyses by paired t-test. The followings are research outcome. 1. In the pre-test, 95% of subjects answered that they already knew what CPR was. but only 82% described correctly what CPR was. 49% learned CPR before, and 80s5 of them learned at high school. 2. 37 questions scores increases, and 10 questions scores decreased. 3 questions didnt change their score. After getting training, ratio of 80% correct score significantly increased 4 times. 3. In post-test. knowledge level of trainees increased compared to that of pre-test. (t=-15.075, p=.000) 4. Competence level also increased (t=-14.86, p=.00). In result, after getting CPR training, most CPR knowledge increased except open the air tract, toddler CPR, and alternative behavior when the air tract is blocked. CPR training needs to extend the educational scope not only CPR lecture but also psychomotor skill practice. CPR trainees are in need of appropriate feedback as well as enough opportunities of skill practice.

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