• Korea Journal of Hospital Management
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• v.4 no.2
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• pp.286-304
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• 1999

The purpose of the study was to analysis physician's prescribing behavior. Data was collected from 320 medical doctors of 10 general hospitals from August to September in 1996. The major findings are as follows; 1) Prescribing dosage: 74% of total selected middle dosage. Resident doctors used maximum dosage. 2) The number of similar antibiotics: 72.4% of total used 1 antibiotic. Surgery depts. and resident doctors selected 2, 3 antibiotics. Physicians to consider of insurance benefit or non insurance benefit used the number of antibiotics less than not to consider. Physicians to think over patient's economic state used less the number of antibiotics than that not to consider. 3) Used term of antibiotics: Total mean was 7.39 days. medical parts had 9.11 days but surgery used 6.41 days. Specialists consumed 6.57 days and residents applied 7.80 days. Physician to reflect result of claim used short term of antibiotics than that don't reflected. 4) Optional order of antibiotics: First antibiotics were selected 68% of total respondents, by medical depts, but secondary, tertiary antibiotics was used surgery depts. Tertiary antibiotics was used residents doctors, universal hospitals, fill beds and over. 5) The number of the items of oral drug : 3-4 the items of oral drug were used 76% of respondent Surgery parts selected 1-2 the items of oral drug, medical depts. selected five and over. Physician to reflect result of claim used less the number of the items of oral drug than that don't reflected. Physician to prescribe different of class of insurance used less the number of the items of oral drug than that don't prescribe different.

• Journal of Embryo Transfer
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• v.5 no.1
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• pp.1-20
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• 1990

Follicular atresia is a universal and characteristic phenomenon of both non-mammalian and mammalian vertebrates. Generally it is estimated that greater than 99% of follicles become atretic in higher domestic animals and human. The number of selected follicles developing to the preovulatory stage are thus fewer. Follicles can become atretic at any stage of development. The previous studies emphasized on descriptive and retrospect aspects of a limited population of the fully grown preovulatory follicle. The main efforts in ovarian physilogical researches are focused on follicular development culminating in ovulation but recent advances have resulted in a better understanding of atresia. Nowadays, recent studies are concentrated on the induction of atresia in a selected population of follicles and of the associated cellular, endocrine, biochemical and molecular changes. The factors initiating atresia and follicle selections are worthy of investigations. Another intriguing question is whether one can predict when a follicle will become atretic, i.e., what biochemical markers indicate that a follicle is destined for atresia. It is generally agreed that atretic process may vary even in antral follicles at different stages of their differentiations and among species. The dicisive factors are follicular responsiveness and the hormonal milieu. Some generalizations can be made on the basis of experimental induction of atresia. Alteration of the pattern of follicular steroid production is associated with the initiation stage of atretic process. Atresia appears to be a process unfolding gradually and affecting progressively in increasing number of functions and components of the follicle. The oocyte may be the latest to be afflicted in the atretic process. The high steroidogenic activity of atretic follicles lends support to the notion that atresia is not necessarily a degenerative process and that atretic follicles may play an essential role in ovarian physiology. The simultaneous occurence of growth and atretic processes may render the search for regulatory mechanisms involved in atresia difficult extremely. The questions such as how follicles are selected to undergo ovulation rather than atresia or what the mechanism of atresia is remain unanswered. However, the factors regulating or modifying ovarian hormonal milieu for the initiation of follicular growth and maturation or of atresia are being elucidated.

• Journal of the Korea Fashion and Costume Design Association
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• v.17 no.3
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• pp.85-98
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• 2015

Modern fashion shows the trend of various styles and the period focusing on only product functions is changed to the period focusing on consumer's sensibility. Consumers show different sensitivities and preference by individual at the stage cognizing and recognizing the stimulation of given image and the method of objective measurement based on the fashion sensible vocabularies is necessary to measure fashion sensibility. Therefore, this research is significant to examine differences of preference to classic fashion by generation and awareness for sensible vocabularies and suggest methodology of design sensible evaluation research through the quantitative evaluation objectifying subjective sensibility. For the method of research, precedent theses related to classic, concept and characteristics of classic in books and definition and characteristics by generation were examined, the best 3 domestic portal sites were selected and adjective vocabularies and images related to classic were collected from 2010 to 2014. Among the 206 adjectives collected, vocabularies whose average is more than 3.5 were drawn by 5-point Likert scale for fashion expert group. And, among the total 306 images collected, 21 representative images were selected by preliminary investigation of fashion expert group. For the classic images and vocabularies selected, frequency analysis, factor analysis and variance analysis were conducted by SPSS 19.0. The results of analysis are as follows. Preference to classic fashion image by generation was analyzed. As a result, both of two generations selected classic fashion as the most classic one. The images of the next orders were analyzed. As a result, Y generation selected basic classic fashion image which is casual with high activity as a classic one. Baby boom generation selected ancient classic fashion image, so there were differences in preference for classic by generation. As a factor analysis on classic adjective vocabularies, they could be divided into 5 factors such as basic form, attractive form, traditional form, vintage form and active form and they verified that credibility of all measuring variables for classic sensible vocabularies was achieved. Differences of classic sensible vocabularies by classic fashion image and generation were examined. As a result, generation and classic fashion image made a significant effect on five factors. Therefore, there were differences of the awareness on classic fashion images and sensible vocabularies among the generations and this thesis can be a fundamental material which objectifies subjective sensibility and suggests the methodology of new research.

• Transactions of the Korean Society of Automotive Engineers
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• v.5 no.3
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• pp.182-190
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• 1997

Recently to develope an automobile with better properties, much researches and investments are executed in many countries. In this paper, it is intended to minimize the weight of an engine block without changing the dynamic characteristics. The weight minimization is executed by the sensitivity of the natural frequency of the engine block. To decrease the engine weight, much less thickness than the original thickness of the engine is selected to initial value and the structure modification is performed to recover the dynamic characteristics of the engine. Here, the original thickness of the engine is 8mm and the initial thickness is selected to 5mm, 6mm and the number if the natural frequencies fitted are 2, 6, 7, respectively. As the results, it is found that; (1) the weight of each case could be reduced without changing the objective natural frequencies. Specially, in the case of fitting 2 natural frequencies with 5mm initial thickness the weight could be reduced to 4.21kg(23.3% for engine weight). (2) according to the driving frequency range of engine, the weight minimization could be performed choicely, (3) improving a vibration characteristics of a orignal structure, the weight minimization could be performed.

• International Journal of Highway Engineering
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• v.18 no.3
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• pp.33-45
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• 2016

PURPOSES : Concrete pavement has been used in the construction of the Jungbu expressway in 1987. More than 60% of the pavement on the expressway is currently made of concrete, but most has been used far beyond their design life. Pavement life has been extended through routine maintenance or overlay. However, the structural capacity of the pavement has reached its limit, and extensive rehabilitation/reconstruction with long time traffic blocking should be considered. The three following issues on concrete rehabilitation/reconstruction will be discussed: (1) economic comparison of asphalt inlay and asphalt overlay, (2) economic comparison preventive overlay on a section which is currently good and routine overlay on the section which will be poor, and (3) economic analysis of early-strength concrete when it is used in concrete reconstruction. METHODS : First, various life cycle cost analysis tools were compared, and the proper tool for the extensive rehabilitation/reconstruction was selected. Second, a sensitivity analysis of the selected tool was performed to find the influential input variables, which should be carefully selected in the analysis. Third, three case studies, which can be issues in the rehabilitation/reconstruction of the expressway concrete pavement in Korea, were performed. RESULTS : Asphalt overlay without milling the deteriorated concrete showed 18~25% lower life cycle cost than the current asphalt inlay with milling. The good current preventive overlay on the section was economically justified within the scope of this study. The construction cost limit of the early strength concrete was suggested to be economical for 1, 3, and 7 days of construction alternative opening. CONCLUSIONS : CA4PRS was a viable tool for comparing various rehabilitation/reconstruction issue alternatives. Several concrete issues associated with the rehabilitation/reconstruction of the deteriorated concrete pavement were discussed as mentioned above.

• Korean Journal of Community Nutrition
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• v.13 no.4
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• pp.463-475
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• 2008

This study investigated intake patterns of health functional foods(HFF) in elementary school children and requirements of their parents in the Daejeon area using a questionnaire by 432 parents. Participating parents were composed of female, 83.6% and male, 16.4%. Most of the parents were in their 40's(53.0%) and 30's(45.8%). 47.9% of the children were male and 52.1% were female. The school year of the children was distributed evenly, ranging from the first year to the sixth year. The intake rate of HFF for parents appeared to be 65.3% and for children it appeared to be 63.2%. The primary reason of using HFF to their child was 'For health promotion'(54.4%); the largest reason of non-using HFF was 'Do not feel necessity because is healthy'(48.8%). In regards to purchase place, 'Drugstore' was most selected by 26.1%, while the largest amount of purchase motive was 'Decided by oneself for children's health'(37.7%). The average expense per month was, 'Less than 50 thousand portion'(20.3%). The intake period, 'less than 6 months' was won' for 54.9%. For intake items, 'Vitamin supplementation products' was the largest portion'(20.3%) was indicated. The intake period, less than 6 months' was the most selected by 51.3%. Most people(66.7%) selected '1 kind' of intake item. As for intake effect, 45.4% claimed 'A little help'. In regard to experiencing side effects, 'Is not' was 92.7%, however, diarrhea, nettle rash, nausea etc. were a little. The biggest problem of HFF was 'Falsehood/exaggerative advertisement' as identified by 53.1%. For improvement of the HFF system was, 'Verify by more strict formality' as selected by 55.8%. In regards to experience of nutrition education on HFF, 'Is not' was most selected by 51.0%. The most desirous form of nutrition education was, 'Simple paper material'(31.3%). The most desirous content of nutrition education was, 'nutritional management of classified by life cycle'(37.2%). Therefore, HFF must be used properly to promote the health and growth development of children by acquiring scientific and reasonable information about the ability and usage of the food.

• Toxicological Research
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• v.17 no.3
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• pp.181-186
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• 2001

The estrogenic potency of bisphenol A using reverse trancriptase-PCR response of liver vitellogenin mRNA in male carp was studied. For this, six combination of primers which were synthesized on the basis of cDNA consensus region of various species, were evaluated and one pair of primers was selected as the best to show 286 bp size-transcript. By using the selected primers, vitellogenin mRNA induction in carp treated with bisphenol A was measured and the chemical showed dose-and time-dependent Induction response. From this result, it was concluded that RT-PCR technique wing the selected primers in this study can be wed to monitor the estrogenic effects exerted In carp living in Korean freshwater.

• Steel and Composite Structures
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• v.20 no.2
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• pp.399-412
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• 2016

This paper evaluates the seismic response of three dimensional steel space buildings using the spread plastic hinge approach. A numerical study was carried out in which a sample steel space building was selected for pushover analysis and incremental nonlinear dynamic time history analysis. For the nonlinear analysis, three earthquake acceleration records were selected to ensure compatibility with the design spectrum defined in the Turkish Earthquake Code. The interstorey drift, capacity curve, maximum responses and dynamic pushover curves of the building were obtained. The analysis results were compared and good correlation was obtained between the idealized dynamic analyses envelopes with and static pushover curves for the selected building. As a result to more accurately account response of steel buildings, dynamic pushover envelopes can be obtained and compared with static pushover curve of the building.

• Earthquakes and Structures
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• v.8 no.1
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• pp.133-152
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• 2015

This paper investigates the soil effect on seismic behaviour of reinforced concrete (RC) buildings by using the spread plastic hinge model which includes material and geometric nonlinearity of the structural members. Therefore, typical reinforced concrete frame buildings are selected and nonlinear dynamic time history analyses and pushover analyses are performed. Three earthquake acceleration records are selected for nonlinear dynamic time history analyses. These records are adjusted to be compatible with the design spectrum defined in Turkish Seismic Code. Interstory drifts and damages of selected buildings are compared according to local soil classes. Also, capacity curves of these buildings are compared with maximum responses obtained from nonlinear dynamic time history analyses. The results show that, soil class influences the seismic behaviour of reinforced concrete buildings, significantly.

• Archives of Pharmacal Research
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• v.6 no.1
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• pp.7-16
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• 1983

A methadone-diazepam interaction study in rats was performed in which conjugated metabolites of methadone were analyzed using deuterated biosynthetic internal standards. Diazepam (5mg/kg) was given to rats through a cannulate djugular vein and a subcutaneous dose of methadone (10mg/kg) was given. Bile was collecte through the cannulate dbile duct over a period of 24 hours. The deuterium label of the internal standards was found to be stable under conditions of the prolonged incubation. There was no significant difference in the excretion of the metabolites between the control and the diazepam treated rats. Feasibility of using biosynthetic internal standards with selected ion monitoring was established for the drug metabolism and kinetic studies.