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A Systematic Review on Antihypertensive Effects of Oryeong-san (오령산의 고혈압 치료 효과에 대한 체계적 고찰 : 임상 논문을 중심으로)

  • Lee, Hye-Yoon;Kang, Ki-Wan;Lee, Eun;Lee, Seung-Ho;Han, Chang-Ho;Jang, In-Soo
    • The Journal of Internal Korean Medicine
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    • v.34 no.3
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    • pp.289-297
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    • 2013
  • Objectives : The purpose of this study was to review the clinical studies on antihypertensive effects of Oryeong-san. Methods : We searched papers using KTKP, Oasis, CNKI, PubMed, Embase, Science Direct, CINAHL, J STAGE and CiNii, and the key words "Oryeong-san (韓)", "Wuling-san (中)", "Gorei-san (日)", and "Hypertension" were used. Search range included randomized controlled trials (RCTs), clinical reports, reviews and animal experiments. Papers not matched with inclusion criteria were excluded. Results : A total 479 studies were found, with 457 excluded during title and screening. After scanning 22 papers, a final 3 RCTs and 6 case reports were selected and analyzed. In the 3 RCTs, the number of patients varied between 65 and 156. Patients with hypertension were randomized into groups for treatment group and control group. They were all treated with antihypertensive drugs (Vamlodipine Besylate, Benazepril, Perindopril); the treatment group was also given modified Oryeong-san. After treatment, results were that blood pressure was significantly decreased in the treatment group, compared to the control. The other 6 case reports reported that modified Oryeong-san alone or the combination of Oryeong-san plus antihypertensive drugs had beneficial effects on blood pressure. Conclusions : Oryeong-san appears to be effective in improving blood pressure and hypertension-related symptoms. The results of this study could be applied to clinical treatment of hypertension. Further large-scale clinical researches should be conducted.

Usefulness of p16INK4a Immunocytochemical staining for the Differentiation between Atrophy and ASCUS in Diagnosis of Uterine Cervical Cancer

  • Hye Ryoung Shin;Taekil Eom;Wan-Su Choi
    • Biomedical Science Letters
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    • v.29 no.3
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    • pp.144-151
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    • 2023
  • A Pap smear is the most important screening test for the diagnosis of cervical cancer. However, subjective judgment by the operator cannot be excluded, and replicability may greatly be reduced if uncertain specimens are examined. Examiners often experience difficulties in differentiating atrophy with inflammatory changes and ASCUS when diagnosing squamous epithelial lesions from a pap smear. Reports often vary between cytologists and pathologists, and misdiagnosis may result in delayed follow-ups and advanced diseases. Hence, auxiliary examinations are necessary when confusing results between atrophy and ASCUS are obtained. The importance of p16INK4a activation due to HPV infection, which is an important factor in the outbreak of cervical cancer, has been highlighted. Recent studies have reported that p16INK4a immunocytochemical staining and HPV high-risk type tests using liquid-based cervical specimens are effective to detect the presence of lesions of grade HSIL or higher in patients with ASC-H. However, no research exists on the utility of HPV and p16INK4a tests on the differential diagnosis of atrophy and ASCUS. This study focused on whether p16INK4a immunocytochemical staining and HPV tests can help diagnose borderline lesions between atrophy and ASCUS. The results reported that p16INK4a activation can significantly (P<0.001) differentiate atrophy from ASCUS in atrophic lesions infected with High risk-HPV. Therefore, it may be concluded that p16INK4a immunocytochemical staining is an effective auxiliary test in lesions infected with HR-HPV when atrophic lesions are difficult to differentiate by morphology. Such results are expected to help decide on adequate follow-up and treatment.

Productivity Measurement Model Based on Quality Cost (품질 코스트를 적용한 생산성측정 모형)

  • Lee, Jae-Ung;Sin, Yong-Baek
    • Journal of Korean Society for Quality Management
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    • v.21 no.2
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    • pp.48-60
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    • 1993
  • We have depended upon the quantitative analysis for productivity measurement. and excluded the qualitative analysis from productivity measurement. But I think that the qualitative analysis must be considered so as to get a effective productivity measurement This paper intened to establish improvement productivity measurement adopted quality cost of all the qualitative elements.

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Study on White Precipitate in Most of Waters after Thawing (물이 해동한 다음 발생하는 휜 침전물의 정성분석 및 이온의 변화)

  • 윤수철;박해룡;윤형식;김창수
    • Journal of Food Hygiene and Safety
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    • v.17 no.1
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    • pp.15-19
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    • 2002
  • The objectives of this study were to investigate the change of silicon, cations and anions dissolved in water before and after thawing, and analyzed what the white-colored precipitate (WP) farmed after thawing was composed of. The silicon concentration that has been changed might have been compared with the weight of WP under water-free state. The major component of WP has been approved to be a silicon, while calsium was only a little contained. As the weight of WP has been nearly equal to the reduced silicon concentration, the weight of its could be changeable calculated by silica (SiO$_2$) molecular weight. Therefore, WP could have been presumed to be a silica. The more silicon concentration was increased, the more weight of silicon was increased. Except for the sample "C", the amounts of cations and anions could be found to be unchangeable nearly. As a result of that, WP has been apparent to be silica itself while most of ions (excluded with Si) of any others were not changed.

Heavy Metal Uptake by Native Plants in Mine Hazard Area (광해지역 토착 자생식물에 의한 중금속 흡수)

  • Choi, Hyung-Wook;Choi, Sang-Il;Yang, Jae-Kyu
    • Journal of Soil and Groundwater Environment
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    • v.15 no.3
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    • pp.27-33
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    • 2010
  • The purpose of this study was in search of native plant species showing metal-resistant property and excessively accumulating heavy metals in metal-contaminated soil or abandoned mines as well as in evaluation of applicability of phytoremediation. In the study area, species showing excessively accumulating heavy metals were a shepherd´s purse, pampas grass, a Korean lettuce, a Hwansam vine, the Korean persicary, a foxtail, a goosefoot, and a water pepper. The first screened plant species in Sambo mine were as shepherd's purse, Korean lettuce and pampas grass Among them the shepherd´s purse can be excluded because it is a seasonal plant and has lower removal capacity for heavy metals. The Korean lettuce was also excluded because of having lower removal capacity for heavy metals. Pampas grass is a highly bionic plant species constantly growing from spring. However it has weak points such as little accumulation capacity for zinc as well as small values of an accumulation factor and a translocation factor. Another problem is regarded as removal of roots after the clean up if pampas grass is applied to a farmland. In Sanyang mine, wormwood and Sorijaengi were considered as adaptable species.

Impact of dental imaging on pregnant women and recommendations for fetal radiation safety: A systematic review

  • Thiago Oliveira Gamba;Fernanda Visioli;Deise Renata Bringmann;Pantelis Varvaki Rados;Heraldo Luis Dias da Silveira;Isadora Luana Flores
    • Imaging Science in Dentistry
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    • v.54 no.1
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    • pp.1-11
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    • 2024
  • Purpose: This study was conducted to investigate the safety of dental imaging in pregnant women with respect to fetal health. Materials and Methods: Searches were conducted of the PubMed, Scopus, and Web of Science databases in May 2023. The inclusion criteria encompassed cross-sectional and longitudinal studies that focused on the analysis of diagnostic dental imaging in pregnant women, as well as studies utilizing phantoms to simulate imaging examinations. The exclusion criteria consisted of reviews, letters to the editor, book chapters, and abstracts from scientific conferences and seminars. Results: A total of 3,913 articles were identified. Based on a review of the titles and abstracts, 3,892 articles were excluded, leaving 21 articles remaining for full-text review. Of these, 18 were excluded, and 4 additional articles were included as cross-references. Ultimately, 7 articles underwent quantitative-qualitative analysis. Three retrospective studies were focused on pregnant women who underwent dental imaging procedures. The remaining 4 studies utilized female phantoms to simulate imaging examinations and represent the radiation doses absorbed by the uterus or thyroid. Conclusion: Few dental radiology studies have been conducted to determine the safe radiation threshold for pregnant women. Additionally, the reviewed articles did not provide numbers of dental examinations, by type, corresponding to this dose. Dental imaging examinations of pregnant women should not be restricted if clinically indicated. Ultimately, practitioners must be able to justify the examination and should adhere to the "as low as diagnostically acceptable, being indication-oriented and patient-specific" (ALADAIP) principle of radioprotection.

A Study on the Site Selection of Public Libraries Using Analytic Hierarchy Process Technique and Geographic Information System (계층분석법과 지리정보시스템을 이용한 공공도서관 입지선정에 관한 연구)

  • Park, Sung-Jae;Lee, Jee-Yeon
    • Journal of the Korean Society for information Management
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    • v.22 no.1 s.55
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    • pp.65-85
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    • 2005
  • This study proposes a new site selection model which reflects integrated opinions of several groups and identifies sites through objectivity of selection procedure. The proposed model consists of two parts, Analytic Hierarchy Process(AHP) and Geographic Information(GIS). This model was applied to Seocho-gu in Seoul. First, library site selection criteria were determined through literature study. Hierarchical relationship based on the questionnaire was determined and refined to be suited to Seocho-gu case. A survey was conducted with three groups, namely, library users, librarians, and public worker. A few inconsistent answers to the survey questionnaire were excluded and the relative importance of each criterion was measured. Next, an overlay method was used and the relative importance was used as a weight for selecting candidates. This process excluded the areas where a library was unable to be built, for example, rivers, military areas, other restricted areas by law, etc. and resulted in seventy-five sites. Five groups of candidates were identified according to the similarity of criteria. Finally, four groups, after eliminating one lowly fitted group, were determined.

The Effect of Program on Emotion of Patients with Schizophrenia: A systematic review of randomized controlled trials (조현병 환자의 정서를 위한 프로그램의 효과: 무작위 대조군 실험연구의 체계적 고찰)

  • Eun-Sol Ju
    • Journal of The Korean Society of Integrative Medicine
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    • v.11 no.2
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    • pp.77-86
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    • 2023
  • Purpose : This study systematically assessed 9 emotion-function programs for schizophrenic individuals that have been implemented over the past 10 years in Korea and abroad, with the objective of providing clinical grounds and data for further programs. Methods : This study identified 2,558 studies from among those registered in the RISS, KISS, EMbase, PubMed and Scopus databases from 2013 to September 2023, using 'schizophrenia' AND 'emotion' AND ('program' OR 'therapy') as keywords. Of the 2,558 studies retrieved from electronic databases, 602 duplicate papers were excluded. After this process, 1,915 papers that did not meet the study's inclusion and exclusion criteria were excluded based on their titles and abstracts. Following a review of the texts of the remaining 41 papers, nine papers were finally selected, excluding 32 papers according to the selection and exclusion criteria. Results : Programs for the emotional function of patients with schizophrenia have continued to be researched. The results of an evaluation on the quality of the selected literature confirmed that a majority of the reviewed items were "uncertain", confirming that there was a risk of bias. The interventions for emotions included art, cognitive-behavioral, and physical programs, of which art programs were frequently applied. Most of the interventions were implemented in hospitals. The dependent variables for evaluating emotions included emotional expression, depression, anxiety, and positive emotions, and among them, emotional expression was used most frequently. Accordingly, the Berkeley expressivity questionnaire was commonly used as an evaluation tool. Conclusion : This study is significant for intending to analyze domestic and overseas programs for the emotions of patients with schizophrenia, thereby proposing the direction for planning and applying interventions in clinical settings. In follow-up studies, it will be necessary to develop a protocol that confirms interventions according to the settings and patient characteristics of programs and expands the scope of literature reviews.

Pulmonary Atresia with Intact Ventricular Septum (둔형 폐동맥 폐쇄증 1)

  • 손영상
    • Journal of Chest Surgery
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    • v.20 no.2
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    • pp.432-437
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    • 1987
  • Pulmonary atresia with intact ventricular septum is a extremely rare congenital cardiac anomaly. With the history of cyanosis and failure to thrive, this anomaly should not be excluded and emergency management is necessary. Our patient was 69 day-old male with pulmonary atresia which was confirmed by cardiac angiography. Prostaglandin E1 was used for maintenance of pulmonary blood flow preoperatively. Right ventricular outflow reconstruction with pericardial patch and concomitant pulmonary valvotomy were done on beating heart for palliation. With this method, growing of right ventricle and tricuspid annulus are highly expected.

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A Review of the Chinese Traditional Medicine Thesis on the Treatment of Hyperopia (원시(遠視) 치료에 관한 중의(中醫) 논문 고찰)

  • Kang, Jae-Hyun;Hong, Jin-Young;Seo, Hyung-Sik
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.34 no.4
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    • pp.37-48
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    • 2021
  • Objectives : The purpose of this study is to investigate treatment trends on hyperopia of chinese traditional medicine. Methods : We searched papers using CNKI and Pubmed. The keyword used on searching was 'Hyperopia' combined with 'Chinese medicine', 'Acupuncture' and 'herbal medicine'. Searching duration was not specified. The search was conducted from January 2020 to July 2021, and the final selected papers were from 1983 to 2014. Results : Studies found in CNKI were 27 and 20 sutdies were excluded. Studies found in Pubmed were 57 and 57 studies were excluded. Finally 7 sutdies were selected and analyzed. Five studies of selected ones were case reports and two were review papers. Among 5 case reports, two of them used herbal medicine with pressing auricular acupoints with beans. Another one used electronic plum acupuncture only. Another one used acupuncture with electronic heat and pulsed current stimulation. The other one compared acupuncture alone and acupuncture combined with massage. All studies report high efficacy rates on treatments. Conclusions : According to this study we found the possibility of acupuncture and herbal medicine on hyperopia. We expect that further studies will be conducted and the results of them could be actively applied to clinical treatments.