• Structural Engineering and Mechanics
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• 제69권5호
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• pp.487-497
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• 2019

Rapid advances in the engineering applications can bring further areas to provide the opportunity to manipulate anisotropic structures for direct productivity in design of micro/nano-structures. For the first time, magnetic affected wave characteristics of nanosize plates made of anisotropic material is investigated via the three-dimensional bi-Helmholtz nonlocal strain gradient theory. Three small scale parameters are used to predict the size-dependent behavior of the nanoplates more accurately. After owing governing equations of wave motion, an analytical approach based harmonic series is utilized to fine the wave frequency as well as phase velocity. It is observed that the small scale parameters, magnetic field and wave number have considerable influence on the wave characteristics of anisotropic nanoplates. Due to the lack of any study on the mechanics of three-dimensional bi-Helmholtz gradient plates made of anisotropic materials, it is hoped that the present exact model may be used as a benchmark for future works of such nanostructures.

• Structural Engineering and Mechanics
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• 제89권4호
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• pp.335-347
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• 2024

This study pioneers the exploration of creep and shrinkage behavior in ambient-cured geopolymer concrete (GPC), a vital yet under-researched area in concrete technology. Focusing on the influence of sodium hydroxide (NaOH) solution concentration, the research utilizes low calcium fly ash (Class-F) and alkaline solutions to prepare two sets of GPC. The results show distinct patterns in compressive strength development and dry shrinkage reduction, with a 14 M NaOH solution demonstrating a 26.5% lower dry shrinkage than the 16 M solution. The creep behavior indicated a high initial strain within the first 7 days, significantly influenced by curing conditions and NaOH concentration. This study contributes to the existing knowledge by providing a deeper understanding of the time-dependent properties of GPC, which is crucial for optimizing its performance in structural applications.

• Earthquakes and Structures
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• 제11권6호
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• pp.943-966
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• 2016

Recently, magnetorheological elastomer (MRE) material and its devices have been developed and attracted a good deal of attention for their potentials in vibration control. Among them, a highly adaptive base isolator based on MRE was designed, fabricated and tested for real-time adaptive control of base isolated structures against a suite of earthquakes. To perfectly take advantage of this new device, an accurate and robust model should be built to characterize its nonlinearity and hysteresis for its application in structural control. This paper first proposes a novel hysteresis model, in which a nonlinear hyperbolic sine function spring is used to portray the strain stiffening phenomenon and a Voigt component is incorporated in parallel to describe the solid-material behaviours. Then the fruit fly optimization algorithm (FFOA) is employed for model parameter identification using testing data of shear force, displacement and velocity obtained from different loading conditions. The relationships between model parameters and applied current are also explored to obtain a current-dependent generalized model for the control application. Based on the proposed model of MRE base isolator, a second-order sliding mode controller is designed and applied to the device to provide a real-time feedback control of smart structures. The performance of the proposed technique is evaluated in simulation through utilizing a three-storey benchmark building model under four benchmark earthquake excitations. The results verify the effectiveness of the proposed current-dependent model and corresponding controller for semi-active control of MRE base isolator incorporated smart structures.

• 한국정보전자통신기술학회논문지
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• 제13권5호
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• pp.397-402
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• 2020

타입 1 콜라겐 단백질은 인체 내에서 가장 많이 존재하는 단백질이다. 이 단백질은 점탄성 거동을 보이며 이는 힘줄에서도 찾아볼 수 있다. 분자동역학 시뮬레이션 방법에는 rescaling 방법과 reassignment 방법으로 온도를 조절할 수 있다. rescaling 방법은 온도를 주어진 온도로 책정하는 방법이고, reassignment 방법은 원하는 온도로 맥스웰 분포를 이용하여서 온도를 책정하는 방법이다. 우리는 reassignment 방법에서 콜라겐 단백질의 거동이 시간에 따라서 변화하는 현상을 찾아내었다. 반면에 rescaling 방법에서는 시간에 무관하게 거동하였다. 콜라겐에 다른 속도로 인장을 가하였을 경우, 예를 들어 0.5, 1, 2, 5 Å/ps의 속도로 40 Å까지 힘을 가했을 경우, rescaling 방법에서는 속도에 따른 변화가 거의 없었던 반면, reassignment 방법의 경우 대략 80nm, 100nm, 130nm, 180nm까지 인장이 되었음을 보여준다. 이 현상에 대한 물리학적 의미를 명확하게 규명하지는 못하였지만, 단백질에 관한 시뮬레이션을 실행하는데 있어서 주의를 기울여 수행하여야 한다는 점에서 이 논문의 가치가 있다고 생각한다.

• Journal of Microbiology and Biotechnology
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• 제27권6호
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• pp.1065-1070
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• 2017

This study aimed to examine the anti-candidal efficacy of a novel ketone derivative isolated from Diaporthe sp. ED2, an endophytic fungus residing in medicinal herb Orthosiphon stamieus Benth. The ethyl acetate extract of the fungal culture was separated by open column and reverse phase high-performance liquid chromatography (HPLC). The eluent at retention time 5.64 min in the HPLC system was the only compound that exhibited anti-candidal activity on Kirby-Bauer assay. The structure of the compound was also elucidated by nuclear magnetic resonance and spectroscopy techniques. The purified anti-candidal compound was obtained as a colorless solid and characterized as 3-hydroxy-5-methoxyhex-5-ene-2,4-dione. On broth microdilution assay, the compound also exhibited fungicidal activity on a clinical strain of Candida albicans at a minimal inhibitory concentration of $3.1{\mu}g/ml$. The killing kinetic analysis also revealed that the compound was fungicidal against C. albicans in a concentration- and time-dependent manner. The compound was heat-stable up to $70^{\circ}C$, but its anti-candidal activity was affected at pH 2.

• Advances in materials Research
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• 제1권4호
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• pp.245-268
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• 2012

Results of isothermal torsional oscillation tests are reported on melts of linear low density polyethylene and isotactic polypropylene. Prior to rheological tests, specimens were annealed at various temperatures ranging from $T_a$ = 180 to $310^{\circ}C$ for various amounts of time (from 30 to 120 min). Thermal treatment induced degradation of the melts and caused pronounced decreases in their molecular weights. With reference to the concept of transient networks, constitutive equations are developed for the viscoelastic response of polymer melts. A melt is treated as an equivalent network of strands bridged by junctions (entanglements and physical cross-links). The time-dependent response of the network is modelled as separation of active strands from and merging of dangling strands with temporary nodes. The stress-strain relations involve three adjustable parameters (the instantaneous shear modulus, the average activation energy for detachment of active strands, and the standard deviation of activation energies) that are determined by matching the dependencies of storage and loss moduli on frequency of oscillations. Good agreement is demonstrated between the experimental data and the results of numerical simulation. The study focuses on the effect of molecular weight of polymer melts on the material constants in the constitutive equations.

• Journal of Microbiology and Biotechnology
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• 제23권6호
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• pp.750-758
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• 2013

Anthrax is a bacterial disease caused by the aerobic spore-forming bacterium Bacillus anthracis, which is an important pathogen owing to its ability to be used as a terror agent. B. anthracis spores can escape phagocytosis and initiate the germination process even in antimicrobial conditions, such as oxidative stress. To analyze the oxidative stress response in B. anthracis and thereby learn how to prevent antimicrobial resistance, we performed protein expression profiling of B. anthracis strain HY1 treated with 0.3 mM hydrogen peroxide using a comparative proteomics-based approach. The results showed a total of 60 differentially expressed proteins; among them, 17 showed differences in expression over time. We observed time-dependent changes in the production of metabolic and repair/protection signaling proteins. These results will be useful for uncovering the metabolic pathways and protection mechanisms of the oxidative response in B. anthracis.

• Toxicological Research
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• 제28권3호
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• pp.151-157
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• 2012

This paper describes the effects of thermally oxidized tallow on the serum lipids profile and radical scavenging activity (RSA) of the lipids extracted from the different tissues of the rabbits. Tallow was thermally oxidized at $130^{\circ}C$ for 9, 18, 27, 36 and 45 h respectively. Thermally oxidized tallow was fed to the local strain of Himalayan rabbits for one week. Results show that oxidation increases the formation of hydroperoxides and decrease the level of radical scavenging activity of the tallow. The rabbit serum lipids profile showed a dose dependent increase in triglyceride, total cholesterol and LDL-cholesterol. However, no statistically significant increase was observed in the HDL-cholesterol with an increase of oxidation time. Serum glucose and rabbits body weight decrease significantly (p < 0.05) and was highly correlated with the serum lipids profile. The percent RSA of the lipids extracted from the liver, brain and muscles tissues showed a significant decrease with respect to 0.5, 1.0 and 1.5 g/body weight as well as oxidation time. Data suggests that thermal oxidation and use of thermally oxidized beef tallow is harmful and therefore an alternative way of cooking should be used.

• 대한토목학회논문집
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• 제4권3호
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• pp.43-52
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• 1984

본문(本文)은 재생성(再生成)한 해성점토(海成粘土)에 대한 점토(粘土)의 시간효과특성(時間効果特性)과 정규압밀(正規壓密)된 점토(粘土)의 시간의존성거동(時間依存性擧動)을 보편적(普遍的)으로 설명(說明)할 수 있는 구성방정식(構成方程式)과 관계(關係)가 있다. 따라서 본문(本文)에서는 T. Adachi와 F. Oka가 제안(提案)한 구성식(構成式)을 채택(採擇)하였으며 이 구성방정식(構成方程式)은 Cam-clay 이론(理論)을 Perzyna외 탄일점소성연속체이론(彈一粘塑性連續體理論)에 적용(適用)하여 수립(樹立)된 것이다. 그리고 이 구성방정식(構成方程式)이 재생성(再生成)한 무안점토(務安粘土)에 대하여 어떻게 적용(適用)될 것인가를 실험적(實驗的)으로 연구(硏究)한 것이다. 본(本) 연구(硏究)에서 얻어진 결론(結論)의 주요(主要)한 것은 다음과 같다. 1. 등방압밀(等方壓密)과 등방응력완화시험(等方應力緩和試驗)의 결과(結果)로부터 정적(靜的), 동적(動的)인 강복면(降伏面)이 각각 존재(存在)함을 확인(確認)할 수 있었다. 2. 일정변형전단시험(一定變形剪斷試驗)과 응력완화시험(應力緩和試驗)의 결과(結果)로부터 시간효과(時間効果)의 특성(特性) 즉 응력(應力)-변형율(變形率)-시간간(時間間)의 유일(唯一)한 관계(關係)가 존재(存在)함을 알 수 있다. 3. Cam-clay 이론(理論)에 의한 응력경로(應力經路)와 변형율(變形率) 추정(推定)에 있어서 이론치(理論値)와 실험치간(實驗値間)에는 차이(差異)가 있다. 4. Cam-clay 이론(理論)을 Perzyna의 탄일점소성체이론(彈一粘塑性體理論)에 적용(適用)시킨 구성방정식(構成方程式)(6)은 비배수상태(非排水狀態)의 등방응력완화과정중(等方應力緩和過程中) 발생(發生)하는 간극수압(間隙水壓)의 거동(擧動)을 설명(說明)할 수 있다. 그리고, 동일(同一)한 혹은 다른 압밀이력(壓密履歷) 받은 점토(粘土)에 대하여 다른 변형속도(變形速度) 적용(適用)한 비배수(非排水) 3축시험(軸試驗)의 결과(結果)를 예측(豫測)하는데 상당한 적합성(適合性)이 있음을 알았다. 5. 이 구성방정식(構成方程式)에는 8개의 재료상수(材料常數)가 있는데 3축압축시험(軸壓縮試驗)을 통하여 쉽게 얻어진다.

• 대한치과보철학회지
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• 제48권1호
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• pp.55-60
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• 2010

연구 목적: 치과용 레진시멘트의 중합 수축은 수복물이 치아에 정확하게 합착되는 것을 방해하고, 내부 응력의 원인이 되어 치아에 여러 문제점을 일으킬 수 있다. 이러한 임상적인 문제점을 줄이기 위해서 사용하는 치과용 레진시멘트의 중합 수축률에 대해 아는 것이 중요하다. 본 연구에서는 상업적으로 이용되고 있는 몇 가지 레진시멘트의 시간에 따른 중합 수축률을 측정, 서로 비교하고자 하였다. 연구 재료 및 방법: 3종류의 자가 중합형 레진시멘트(Fujicem, Superbond, M bond)와 3종류의 이원 중합형 레진시멘트(Maxcem, Panavia F, Variolink II) 별로 각각 5개의 시편을 이용하였다. 각 재료의 중합 수축률은 Bonded disk method를 이용하여 측정하였다. 안쪽 직경 16 mm, 두께 1 mm 의 동으로 제작된 링을 유리판 ($74\;mm\;{\times}\;25\;mm\;{\times}\;3\;mm$) 위의 중앙에 위치시켜 부착하고, 그 유리판 중앙에 실험 재료를 구 형태로 만들어 올리고, 다른 유리판으로 눌러서 원판 형태 (직경 8 mm, 두께 1 mm)의 시편을 제작하였다. 시편의 중합 수축률은 재료가 중합이 시작된 후 120분동안, $23^{\circ}C$에서 측정하였다. 시간에 따른 수축량에 대한 kinetics curve를얻고, 각 실험 재료의 수축률의 평균값 (%)과 표준편차를 구한 뒤, one-way ANOVA 및 Scheffe post hoc test를 유의수준 0.05 에서 처리하여 그 결과 값을 비교하였다. 결과: 1. 실험에 사용된 Fujicem, Maxcem, M bond, Panavia F, Superbond, Variolink II 은 중합이 시작 된 120 분 후의 중합 수축률이 각각 3.72%, 4.19%, 4.13%, 2.44%, 7.57%, 2.90%의 값을 보였다. 2. Panavia F가 중합 수축률이 가장 작았고, Superbond가 중합 수축률이 가장 컸다 (P<.05). 3. Maxcem 과 M Bond 간에는 유의한 차이가 없었다 (P>.05). 4. 6종류의 레진 시멘트에서 90% 이상의 대부분의 수축은 중합이 개시된 30분 내에 거의 일어났다. 결론: 자가 중합형 레진시멘트의 혼합 후 나타나는 중합 수축이 이원 중합형 레진시멘트보다 천천히 일어나지만, 혼합 120분 뒤의 중합 수축은 이원 중합형 레진 시멘트 보다 유의할 정도로 높았다. 치과용 레진시멘트의 중합 수축은 혼합한 후 30 분내에 대부분 일어난다.