• Journal of Oriental Neuropsychiatry
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• v.24 no.1
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• pp.123-130
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• 2013

Objectives : During several thousand years, Peucedanum Japonicum Thunberg has been considered as a vegetable side dish in Korea. There is folk knowledge that Peucedanum Japonicum Thunberg prevents vascular disease such as stroke. To identify the effects Peucedanum Japonicum Thunberg, we made up its extract and named it as KH020. Then, we employed common carotid artery ligation (CCAl) surgery for vascular dementia model (VDM), and two types doses of per os (per oral: p.o) treatment. Methods : To confirm prevention and recovery effects for vascular dementia, we treated two doses (100, 400 mg/kg) KH020 in male C57BL/6 mouse during 7 days. After treatment, animals were CCAl operated, and given time to recover. Then, animal were tested in a Y-maze and passive avoidance test. Results : Y-maze results demonstrated that cognition and memory performance were decreased in the VDM group, compared to the sham group. KH020 treatment abolished these effects significantly. The results from the passive avoidance test showed the same phenomenon, but it was not statically significant. Conclusions : Therefore, KH020 prevents the onset of vascular dementia. In future studies, we will evaluate KH020 in regard to alzheimer dementia.

• Journal of Multimedia Information System
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• v.4 no.4
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• pp.163-170
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• 2017

Internet of things (IoT) is a new paradigm for collecting, processing and analyzing various contents in order to detect anomalies and to monitor particular patterns in a specific environment. The collected data can be used to discover new patterns and to offer new insights. IoT-enabled data mashup is a new technology to combine various types of information from multiple sources into a single web service. Mashup services create a new horizon for different applications. Environmental monitoring is a serious tool for the state and private organizations, which are located in regions with environmental hazards and seek to gain insights to detect hazards and locate them clearly. These organizations may utilize IoT - enabled data mashup service to merge different types of datasets from different IoT sensor networks in order to leverage their data analytics performance and the accuracy of the predictions. This paper presents an IoT - enabled data mashup service, where the multimedia data is collected from the various IoT platforms, then fed into an environmental cognition service which executes different image processing techniques such as noise removal, segmentation, and feature extraction, in order to detect interesting patterns in hazardous areas. The noise present in the captured images is eliminated with the help of a noise removal and background subtraction processes. Markov based approach was utilized to segment the possible regions of interest. The viable features within each region were extracted using a multiresolution wavelet transform, then fed into a discriminative classifier to extract various patterns. Experimental results have shown an accurate detection performance and adequate processing time for the proposed approach. We also provide a data mashup scenario for an IoT-enabled environmental hazard detection service and experimentation results.

• Korean Journal of Cognitive Science
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• v.24 no.1
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• pp.1-24
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• 2013

The elderly population continues to increase in Korea and there has been a growing interest in understanding normal aging. In response to this public interest, the present paper reviewed human aging research focusing on recently published neuroimaging studies. For the first half of the paper, I reviewed the effects of aging on the brain and cognition. In normal aging, structural changes in the brain include atrophy and volume reduction in the prefrontal and temporal cortices. Functional changes are exhibited in the form of overactivation of the brain. Moreover, age-related cognitive decline is particularly observed in inhibition and memory, which are also associated with the age-related structural changes in the brain. For the second half of the paper, I introduced physical exercise studies showing that exercise played a protective role in the age-related neurocognitive decline. More specifically, engaging in physical exercise (particularly, aerobic exercise) for a relatively long period of time (e. g., > 6 mon.) protected older adults from volume loss in the prefrontal cortex and the hippocampus, and induced better inhibition and memory. These exercise-induced benefits appear to be associated with changes in neuronal levels, indicating that the aging brain is still plastic and this plasticity can be enhanced by physical exercise.

• Journal of Convergence for Information Technology
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• v.10 no.10
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• pp.318-324
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• 2020

The present study was conducted to investigate the influences of emotion priming and the number of negation words on the task of sentential predicate reasoning in groups with or without anxiety symptoms. 3 types of primed emotions and 2 types of stimulus and 3 conditions of negation words were used as a within-subject variable. The subjects were instructed to make facial expressions that match the directions, and were asked to choose the correct answer from the given examples. Mixed repeated measured ANOVA analyses on reaction time first showed main effects for the variables of emotion, stimulus, number of negation words and anxiety level, and the interaction effects for the negation words x anxiety combination. These results are presumably suggested to reflect that externally intervening emotion works on language comprehension in a way that anxiety could delay task processing speed regardless of the emotion and stimulus type, meanwhile the number of negation words can slower language processing only in a anxiety group. Implications and limitations were discussed for the future work.

• The Korean Journal of Rehabilitation Nursing
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• v.11 no.2
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• pp.90-98
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• 2008

Purpose: The purpose of this study was to examine the cognitive function and degree of dementia patient by doing clock drawing test and to explore the relationship among other dementia screening test. Method: The study subjects were 94 dementia in patients department. The data was collected by face to face interview by clinical psychologist from January 2007 to February 2008. The tools were Clock Drawing Test, K-MMSE, K-3MS and CDR Scale. Results: 1) The average score of CDT was 5.13 (2.54), of K-MMSE was 20.53 (4.85), of K-3MS was 61.66 (16.46), and of CDR was 1.2 (.72), those scores showed dementia. 2) There was a statistically the significant difference in CDT (F=2.83, p=.043) and CDR (F=2.00, p=.008) by age. CDT has shown the differences by gender (t=-2.42, p=.018) and education (F=7.66, p=.000). 3) There were significant relationships between CDT and K-MMSE (r=-.294. p=.004), K-3MS (r=-.335, p=.001), and CDR (r=.286, p=.008). Conclusion: It is believed that using CDT which measures the visuospatial ability of dementia patients and K-MMSE which assesses an ability of language and orientation and K-3MS at the same time helps examining the beginning and the progressive degree of dementia more easily and objectively.

• Journal of Korean Academy of Nursing Administration
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• v.14 no.3
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• pp.229-240
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• 2008

Purpose: To develop the patient classification system based on the resource utilization for reimbursement of long-term care hospitals in Korea. Method: Health Insurance Review & Assessment Service (HIRA) conducted a survey in July 2006 that included 2,899 patients from 35 long-term care hospitals. To calculate resource utilization, we measured care time of direct care staff (physicians, nursing personnel, physical and occupational therapists, social workers). The survey of patient characteristics included ADL, cognitive and behavioral status, diseases and treatments. Major category criteria was developed by modified delphi method from 9 experts. Each category was divided into 2-3 groups by ADL using tree regression. Relative resource use was expressed as a case mix index (CMI) calculated as a proportion of mean resource use. Result: This patient classification system composed of 6 major categories (ultra high medical care, high medical care, medium medical care, behavioral problem, impaired cognition and reduced physical function) and 11 subgroups by ADL score. The differences of CMI between groups were statistically significant (p<.0001). Homogeneity of groups was examined by total coefficient of variation (CV) of CMI. The range of CV was 29.68-40.77%. Conclusions: This patient classification system is feasible for reimbursement of long-term care hospitals.

• Korean Journal of Health Education and Promotion
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• v.20 no.3
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• pp.61-76
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• 2003

Substance abuse among teenagers has been spreading widely and become a serious social problem. However, teachers hardly realize its importance. Recently, substance abuse prevention programs show a tendency towards one time education. This study aims to research the effect of substance abuse prevention on high school students using the Life Skills Training Program. Two classes(36 students in the experimental group, 35 in the control group) at W High School in Daejeon were randomly sampled for this study from May to June 2002. Substance knowledge and attitude, problem solving, and assertiveness were examined as Pre and Post-Tests. The data was analyzed using frequencies, t-test, means, and covariance(ANCOVA). The results of this study were as follows； 1. Compared with the control group, substance knowledge in the experimental group was significantly improved(F＝176.317, P＝.000). And compared with the control group, substance attitudes in the experimental group were improved significantly.(F＝207.682, P＝.000). 2. Compared with the control group, cognitions to problem solving in the experimental group was significantly improved(F＝100.937, P＝.000). 3. Compared with the control group, assertiveness behaviors in the experimental group were increased significantly(F＝207.255, P＝.000). The study showed that Substance Abuse Prevention of High School Students was effective in improving substance knowledge and attitude, cognition to problem solving, and assertiveness behavior. Some suggestions based on the result are as follows； 1. Substance abuse preventive programs must be practiced properly and systematically with high school students in their regular classes. 2. Various preventive education programs must be developed for substance abuse where high school students can join in a community center, such as Community Welfare Center, Alcoholic Counseling Center, and Mental Health Center. 3. For the furthering of substance abuse preventive education, there must be continued research about not only students with problems of substance misuse and abuse, but also students without them. 4. There must be early determination of students with problems of substance misuse to be able provide school social workers with the opportunity for intervention.

• Research in Community and Public Health Nursing
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• v.4 no.2
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• pp.91-99
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• 1993

This research is undertaken for the purpose of providing basic data to improve the occupational health service for future. 415 workers of 46 firms in Seoul are included in this data points. Results from this analyzing are the following. 1) The level of knowledge, attitude and practice of workers on the occupational health is moderate. 2) The cognition of necessity about special health examination gains the highest point(3.94), but the understanding of the occupational health educational program gains the lowest point (.85) in the knowledge region. 3) In the attitude region, the highest point is marked by the workers' prudence of expending time on medical examination(3.45). The lowest one by the workers' feeling of satisfaction of the follow-up service after medical examination(1.79). 4) The workers' participation in medical examination is the most active(3.15), and that in occupational health education in the least active(.86) in the practical region.

• The Journal of the Korea Contents Association
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• v.14 no.10
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• pp.171-179
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• 2014

The purpose of this study was to analyze the relationships among social activities, self-efficacy and the level of life satisfaction of the elderly. 394 structured questionnaires were collected from the elderly aged 60 plus who live in Joonggu, Dajeon City, and the frequency analysis, factor analysis, reliability analysis and hierarchical regression analysis were carried out through SPSS Ver 18.0. The results were as follows. First, the frequencies of the learning and cultural activity, social collective activity and family community activity showed relatively high. The participation frequencies showed as 30% for one or two times per week and 20% for nearly no. And the participation time lasted only one or two hours which meat very low level. Second, the positive cognition on the participation in social activities and taking an active part in social activities had an positive effect on self-efficacy and the level of life satisfaction of the elderly.

• Biomolecules & Therapeutics
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• v.21 no.6
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• pp.462-469
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• 2013

Eucommia ulmoides Oliv. Bark (EUE) is commonly used for the treatment of hypertension, rheumatoid arthritis, lumbago, and ischialgia as well as to promote longevity. In this study, we tested the effects of EUE aqueous extract in graded doses to protect and enhance cognition in scopolamine-induced learning and memory impairments in mice. EUE significantly improved the impairment of short-term or working memory induced by scopolamine in the Y-maze and significantly reversed learning and memory deficits in mice as measured by the passive avoidance and Morris water maze tests. One day after the last trial session of the Morris water maze test (probe trial session), EUE dramatically increased the latency time in the target quadrant in a dose-dependent manner. Furthermore, EUE significantly inhibited acetylcholinesterase (AChE) and thiobarbituric acid reactive substance (TBARS) activities in the hippocampus and frontal cortex in a dose-dependent manner. EUE also markedly increased brain-derived neurotrophic factor (BDNF) and phosphorylation of cAMP element binding protein (CREB) in the hippocampus of scopolamine-induced mice. Based on these findings, we suggest that EUE may be useful for the treatment of cognitive deficits, and that the beneficial effects of EUE are mediated, in part, by cholinergic signaling enhancement and/or protection.